Fatal Illness (fatal + illness)

Distribution by Scientific Domains


Selected Abstracts


Friedrich Nietzsche's mental illness , general paralysis of the insane vs. frontotemporal dementia

ACTA PSYCHIATRICA SCANDINAVICA, Issue 6 2006
M. Orth
Objective:, For a long time it was thought that Nietzsche suffered from general paralysis of the insane (GPI). However, this diagnosis has been questioned recently, and alternative diagnoses have been proposed. Method:, We have charted Friedrich Nietzsche's final fatal illness, and viewed the differential diagnosis in the light of recent neurological understandings of dementia syndromes. Results:, It is unclear that Nietzsche ever had syphilis. He lacked progressive motor and other neurological features of a progressive syphilitic central nervous system (CNS) infection and lived at least 12 years following the onset of his CNS signs, which would be extremely rare for patients with untreated GPI. Finally, his flourish of productivity in 1888 would be quite uncharacteristic of GPI, but in keeping with reports of burgeoning creativity at some point in the progression of frontotemporal dementia (FTD). Conclusion:, We suggest that Nietzsche did not have GPI, but died from a chronic dementia, namely FTD. [source]


Anticipatory grieving among parents living with a child with cancer

JOURNAL OF ADVANCED NURSING, Issue 9 2010
Ekhlas Al-Gamal
al-gamal e. & long t. (2010) Anticipatory grieving among parents living with a child with cancer. Journal of Advanced Nursing,66(9), 1980,1990. Abstract Aim., This paper is a report of a comparative study of anticipatory grief of parents of children newly diagnosed with cancer and those whose children were diagnosed 6,12 months earlier. Background., Public perceptions of cancer as a fatal illness persist despite improved prognosis for children. Parents may experience feelings of despair, hopelessness, and worthlessness , the most common psychological expressions of anticipatory grief. With a focus on developing more effective therapeutic intervention, healthcare professionals have developed greater interest in the concept of anticipatory grief. Method., One hundred and forty parents, divided between ,newly diagnosed' and ,6,12 months after diagnosis' groups, were recruited in 2006 from two hospitals representative of the healthcare sector in Jordan. Structured interviews were conducted to assess anticipatory grief, using the Marwit and Meuser Caregiver Inventory: Childhood Cancer. Analysis was performed using t -tests. Results., Fewer than half of the parents in both groups reported being at peace with themselves and their situation in life. Parents of newly diagnosed children reported more severe anticipatory grief responses than those in the second group. No statistically significant differences were found in responses between mothers and fathers. Conclusion., Healthcare professionals should encourage parents to discuss negative feelings related to their child's illness and potential outcome. Hospital policies need to include the provision and promotion of support group services for parents, and nurses should encourage parents to exploit such services. [source]


Oral pemphigus: long term behaviour and clinical response to treatment with deflazacort in sixteen cases

JOURNAL OF ORAL PATHOLOGY & MEDICINE, Issue 4 2000
Michele D. Mignogna
Abstract: Systemic corticosteroids remain the mainstay of therapy for pemphigus. Their use has transformed what was almost invariably a fatal illness into one whose mortality is now below 10%. Unfortunately, the high doses and prolonged administration of corticosteroids that are often needed to control the disease result in numerous side effects, many of which are serious or even life-threatening. Sixteen patients affected by oral pemphigus vulgaris were retrospectively examined to illustrate the natural course of the disease and to describe the efficacy of the treatment we utilised. Deflazacort, used with azathioprine, is the steroid of first choice in our therapeutic protocols, while cyclophosphamide and methylprednisolone "pulse therapy" are reserved for cases unresponsive to high doses of oral corticosteroids. In addition, the literature on oral pemphigus vulgaris was reviewed with respect to clinical history, signs and symptoms, management, and treatment outcome. [source]


Giancarlo Rastelli: The Scientist, the Man

CLINICAL CARDIOLOGY, Issue 9 2007
Umberto Squarcia M.D
Doctor Giancarlo Rastelli graduated from the University of Parma, Italy (cum laude) in July 1957, and in 1961, moved to the Mayo Clinic, Rochester, New York. The name of Dr. Rastelli is recognized worldwide for the classification of the atrioventricular (AV) canal and for the procedure relating to the anatomical repair of transposition of the great arteries (TGA) with ventricular septal defect (VSD) and pulmonary stenosis (PS). The most extraordinary aspect of his successful research work was that it was mostly done during the five years when Dr. Rastelli was fighting against his fatal illness. He died at the age of 36 years. Dr. Rastelli's fame as a scientist now belongs to the history of medicine. Copyright © 2007 Wiley Periodicals, Inc. [source]