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Facile Entry (facile + entry)

Distribution by Scientific Domains
Chemistry100%

Selected Abstracts

ChemInform Abstract: Phosphine-Promoted [3 + 3] Annulations of Aziridines with Allenoates: Facile Entry into Highly Functionalized Tetrahydropyridines.

CHEMINFORM, Issue 38 2009
Hongchao Guo
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

Sodium Borohydride,Iodine Mediated Reduction of ,-Lactam Carboxylic Acids Followed by DDQ Mediated Oxidative Aromatization: A Facile Entry to N-Aryl-formylpyrroles.

CHEMINFORM, Issue 23 2005
Pranab Haldar
No abstract is available for this article. [source]

Lewis Acid Promoted Annulation of p-Quinoneimines by Allylsilanes: A Facile Entry into Benzofused Heterocycles.

CHEMINFORM, Issue 35 2002
Vijay Nair
Abstract For Abstract see ChemInform Abstract in Full Text. [source]

Fluorinated Analogues of Amicetose and Rhodinose , Novel Racemic and Asymmetric Routes

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 7 2009
Jonathan M. Percy
Abstract Trifluoroethanol was converted into difluorinated (racemic) analogues of amicetose and rhodinose by metallated difluoroenol acetal chemistry, protection, release of the latent difluoromethyl ketone, stereoselective reduction and ozonolysis in acidic methanol. A fortuitous separation of diastereoisomers allowed the diastereoisomeric pyranoses to be obtained cleanly. Though reductive defluorination allowed a facile entry to the route, the corresponding monofluoro sugar analogues could not be separated. Instead, Sharpless asymmetric epoxidation followed by epoxide ring-opening with an unusual nucleophilic fluoride source allowed enantiomerically highly enriched and selectively protected fluorodiols to be obtained. Ozonolysis then afforded the methyl pyranosides, which could be transformed in a number of ways. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009) [source]

Facile regiospecific syntheses of N -,,N -1(,)-dialkyl-l-histidines

JOURNAL OF HETEROCYCLIC CHEMISTRY, Issue 6 2007
Surendra Kumar Nayak
Two diverse methodologies describe the first synthesis of suitably protected N -,,N -1(,)-dialkyl-Lhistidine derivatives. Synthesis of suitably protected N -,,N -1(,)-dialkyl-L-histidines 7-9 containing different alkyl groups at the N -, and N -1(,) positions was achieved in four steps starting from L-histidine methyl ester. Whereas, in the one-step alternate route N -,-Boc-L-histidine methyl ester upon direct and simultaneous N -, and N -1(,) alkylation with various alkyl halides in the presence of sodium hydride in DMF easily afforded N -,,N -1(,)-dialkyl-L-histidines 14 containing identical alkyl group at the N -, and N -1(,) positions in high yields. Both procedures allowed facile entry to methyl and other higher alkyl groups at the N -,-position of the histidine ring [source]