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Facial Transplantation (facial + transplantation)

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Medical Sciences100%

Selected Abstracts

An Ongoing Issue Concerning Facial Transplantation

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 5 2010
C. Strong
The risk of chronic rejection in facial transplantation continues to cause concern. See article by Siemionow and Gordon on page 1290. [source]

Facial transplantation as an option in reconstructive surgery: no mountains too high?

ANZ JOURNAL OF SURGERY, Issue 12 2009
Wojciech B, ogowski
Abstract Background:, Human facial allotransplantation (FA) is a testament to the impressive progress, which was and is still happening in the field of transplantation medicine and reconstructive surgery. Like every pioneering treatment option, FA faces both the clinicians' and public opinion with a huge amount of medical and psychosocial dilemmas, which, in order to introduce FA as a scientifically and socially accepted procedure into clinical practice, need to be discussed, answered and solved. Methods:, This review is based on a detailed literature research in all relevant databases (MEDLINE, PubMed, Cochrane Library, specialist textbooks), however, recent papers (published between 2006 and 2008) were given highest priority for inclusion. Results:, In this review, two main limitations associated with facial tissue allotransplantation, that is, shortage of donations and life-long need for immunosuppressive treatment, are discussed and presented in both psychosocial and medical terms. Conclusion:, Although both of these limitations potentially could successfully inhibit the transformation of FA from an experimental therapy to the treatment of choice for patients with severe functional facial impairment, recent literature suggest that FA will find a meaningful place in facial reconstructive surgery. [source]

An Ongoing Issue Concerning Facial Transplantation

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 5 2010
C. Strong
The risk of chronic rejection in facial transplantation continues to cause concern. See article by Siemionow and Gordon on page 1290. [source]

Overview of Guidelines for Establishing a Face Transplant Program: A Work in Progress

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 5 2010
M. Siemionow
Since 2005, nine face transplants have been performed in four countries: France, the United States (US), China and Spain. These encouraging short-term outcomes, with the longest survivor approaching 5 years, have led to an increased interest in establishing face transplant programs worldwide. Therefore, the purpose of this article is to facilitate the dissemination of relevant details as per our experience in an effort to assist those medical centers interested in establishing a face transplant program. In this article, we address the logistical challenges involved with face transplantation; including essential program requirements, protocol details, face transplant team assembly, project funding, the organ procurement organization and the coroner. It must be emphasized that face transplantation is still experimental and its therapeutic value remains to be validated. All surgical teams pursuing this endeavor must dedicate an attention to detail and should accept a responsibility to publish their outcomes in a transparent manner in order to contribute to the international field. However, due to its inherent complexity, facial transplantation should only be performed by university-affiliated medical institutions capable of orchestrating a specialized multidisciplinary team with a long-term commitment to its success. [source]