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Eye Abnormalities (eye + abnormality)
Selected AbstractsModeling and simulation of bioheat transfer in the human eye using the 3D alpha finite element method (,FEM)INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING, Issue 8 2010Eric Li Abstract Computational modeling is an effective tool for the detection of eye abnormalities and a valuable assistant to hyperthermia treatments. In all these diagnoses and treatments, predicting the temperature distribution accurately is very important. However, the standard finite element method (FEM) currently used for such purposes has strong reliance on element meshes and the discretized system exhibits the so-called ,overly stiff' behavior. To overcome this shortcoming, this paper formulates an alpha finite element method (,FEM) to compute two-dimensional (2D) and three-dimensional (3D) bioheat transfer in the human eyes. The ,FEM can produce much more accurate results using triangular (2D) and tetrahedron (3D) elements that can be generated automatically for complicated domains and hence is particularly suited for modeling human eyes. In the ,FEM, a scaling factor ,,[0, 1] is introduced to combine the ,overly stiff' FEM model and ,overly soft' node-based finite element method (NS-FEM) model. With a properly chosen ,, the ,FEM can produce models with very ,close-to-exact' stiffness of the continuous system. Numerical results have shown that the present method gives much more accurate results compared with the standard FEM and the NS-FEM. Copyright © 2010 John Wiley & Sons, Ltd. [source] Case study on eye abnormalities in tank-reared hybrid walleyes (Sander vitreus×S. canadensis)AQUACULTURE RESEARCH, Issue 5 2006Mary Ann Garcia-Abiado Abstract Hybrid walleye is important for recreational fisheries and is a potential aquaculture species in the north central region of the United States. Stress related to intensive culture conditions has been documented to cause eye lesions in fish. Finfish eyes do not have eyelids, hence the cornea is permanently exposed to mechanical damage and toxic substances. We documented various disorders of the eye in juvenile hybrid walleyes reared in a flow-through tank system. Abnormalities include exophthalmia, enophthalmia, unilateral loss of globe and bilateral loss of globe. These lesions negatively affected body weight, specific growth rate and condition factor of hybrid walleyes reared in tanks. [source] Premature arthritis is a distinct type II collagen phenotypeARTHRITIS & RHEUMATISM, Issue 5 2010Peter Kannu Mutations in the gene encoding type II collagen (COL2A1) give rise to a spectrum of phenotypes predominantly affecting cartilage and bone. These chondrodysplasias are typically characterized by disproportionately short stature, eye abnormalities, cleft palate, and hearing loss. It is less recognized that mutations in COL2A1 can also present as degenerative joint disease in the absence of any other phenotypic clues. We report 2 Australian families presenting with an isolated arthritis phenotype, segregating as a dominant trait affecting both large and small joints, prior to age 30 years. Sequencing of COL2A1 in the propositi revealed 2 sequence changes resulting in glycine substitutions in the triple-helical domain of type II collagen. We review the increasing evidence implicating COL2A1 mutations in individuals presenting with isolated degenerative joint disease, aiming to alert physicians who assess these patients to this possibility. The importance of finding a COL2A1 mutation in such patients lies in the subsequent ability to accurately assess recurrence risks, offer early (including prenatal) diagnosis, and provide information regarding the natural history of the condition. Most importantly, it enables at-risk individuals to be identified for implementation of preventative strategies (i.e., weight loss, joint-friendly exercise programs) and early ameliorative management of their condition. [source] Erythropoietic protoporphyria with eye complicationsTHE JOURNAL OF DERMATOLOGY, Issue 11 2007Hiromi TSUBOI ABSTRACT We herein report a case of erythropoietic protoporphyria (EPP) complicated by a decrease in eyesight that occurred in a Japanese male. An ophthalmologist initially thought that the eyesight loss might be the result of idiopathic optic nerve atrophy due to a vascular obstruction in the fundus. There are no previous reports of EPP cases with eye complications. However, an eye abnormality has been reported in an animal model of protoporphyria after long-term, low-level exposure to blue light. As a result, in our case, it is therefore possible that a relationship may have existed between EPP and the onset of eye complications. [source] | ||||||||||