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Experienced Loss (experience + loss)
Selected AbstractsMaternal resolution of loss and abuse: Associations with adjustment to the transition to parenthoodINFANT MENTAL HEALTH JOURNAL, Issue 2 2004Kim Leon This study examined relationships between mothers' resolution of past loss and abuse and their adjustment to the transition to parenthood. Three groups of mothers were compared: 1) those who were unresolved with respect to loss or abuse (Unresolved Loss/Abuse), 2) those who had experienced loss or abuse, but were considered resolved (Resolved Loss/Abuse), and 3) those who had not experienced loss or abuse (No Loss/Abuse). Mothers in the Resolved Loss/Abuse group reported more negative perceptions of the transition to parenthood than did mothers in the No Loss/Abuse group, which may reflect a greater awareness of negative emotions and a greater ability to communicate openly about them. Although mothers who have experienced loss or abuse and appear to have resolved these experiences may be at risk for distress during the transition to parenthood, they do not appear to be at risk for insensitive care giving. Unresolved loss, however, was associated with less sensitive care giving. The findings of this study highlight the importance of examining current state of mind regarding past experiences when investigating relationships between childhood loss and abuse and adjustment to subsequent life transitions. ©2004 Michigan Association for Infant Mental Health. [source] The efficacy and safety of a third anti-TNF monoclonal antibody in Crohn's disease after failure of two other anti-TNF antibodiesALIMENTARY PHARMACOLOGY & THERAPEUTICS, Issue 1 2010M. ALLEZ Summary Background, Adalimumab (ADA) and certolizumab pegol (CZP) have demonstrated efficacy in Crohn's disease (CD) patients previously treated with infliximab (IFX). Aim, To assess the efficacy and tolerability of a third anti-TNF in CD after failure of and/or intolerance to two different anti-TNF antibodies. Methods, Crohn's disease patients who received ADA or CZP after loss of response and/or intolerance to two anti-TNF agent were included in this retrospective study. Data were collected using a standardized questionnaire. Clinical response, duration, safety and reasons for discontinuation were assessed. Results, Sixty-seven patients treated with CZP (n = 40) or ADA (n = 27) were included. A clinical response was observed in 41 (61%) at week 6 and 34 patients (51%) at week 20. The probability of remaining under treatment at 3 months, 6 months and 9 months was 68%, 60% and 45%, respectively. At the end of follow-up, the third anti-TNF had been stopped in 36 patients for intolerance (n = 13), or failure (n = 23). Two deaths were observed. Conclusions, The treatment with a third anti-TNF (CZP or ADA) agent of CD patients, who have experienced loss of response and/or intolerance to two anti-TNF antibodies, has favourable short-term and long-term efficacy. It is an option to be considered in patients with no other therapeutic options. [source] The Platysma Myocutaneous Flap: Underused Alternative for Head and Neck Reconstruction,THE LARYNGOSCOPE, Issue 7 2002Wayne M. Koch MD Abstract Objectives The use, advantages, and disadvantages of the platysma flap were assessed. Study Design Retrospective review of the medical records of patients undergoing platysma flap reconstruction of the upper aerodigestive tract from 1987 to 2001. Methods Information regarding the tumor, surgical procedure, flap design, and outcome emphasizing complications and function was extracted. Associations between putative risk factors for flap failure and outcome were assessed using the ,2 test. Results Thirty-four patients underwent reconstruction with platysma flaps. Surgical defects included the oropharynx, oral cavity, and hypopharynx. Nine patients had had prior radiation therapy and all had some dissection of the ipsilateral neck. There were 5 postoperative fistulas (15%), flap desquamation was noted in 6 cases (18%), and 2 patients experienced loss of the distal skin closing the donor site. Complications were not associated with prior radiation. Hospital stay ranged from 5 to 21 days (mean, 10 d). There were no returns to the operating room or need for additional reconstruction. All but 1 patient resumed a normal diet within 3 months of surgery. There were no recurrences of cancer in the dissected neck regions. Conclusions The platysma flap is simple and versatile with properties similar to the radial forearm free flap. The rate of complications is similar to other published series, and problems encountered were manageable using conservative methods with excellent functional and cosmetic outcomes. These facts support the contention that the platysma myocutaneous flap can serve as a viable alternative to free tissue transfer and has advantages over pectoralis major pedicled flaps for reconstruction of many head and neck defects. [source] Use of a probiotic to control lactococcosis and streptococcosis in rainbow trout, Oncorhynchus mykiss (Walbaum)JOURNAL OF FISH DISEASES, Issue 12 2005J Brunt Abstract From a comparison of 125 bacterial isolates recovered from the digestive tract of rainbow trout, Oncorhynchus mykiss, and carp, Cyprinus sp., a culture was obtained which was effective at preventing clinical disease caused by Lactococcus garvieae and Streptococcus iniae when used as a feed additive. The culture, Aeromonas sobria GC2, was incorporated into the feed and fed to rainbow trout (average weight = 20 g) for 14 days at a dose equivalent to 5 × 107 cells g,1 of feed. Whereas the untreated controls experienced losses of 75,100% when challenged intraperitoneally with L. garvieae and S. iniae, the probiotic-treated groups remained healthy with total mortalities of only 0,6%. Formalized and sonicated preparations of GC2 and cell-free supernatant fared less well. The mode of action reflected stimulation of innate immunity, namely an increased number of leucocytes and enhanced phagocytic and respiratory burst activity. [source] The labour market effects of globalization in KenyaJOURNAL OF INTERNATIONAL DEVELOPMENT, Issue 1 2004Damiano Kulundu Manda Since the 1980s, Kenya has been gradually integrating with the global economy. Using both industry-level and firm-level data, the paper examines the effects of globalization on employment and earnings in the Kenyan manufacturing sector. The industry-level analysis suggests that the overall effect of international trade on manufacturing employment has been negative in the 1990s. The firm-level analysis indicates that less skilled workers experienced losses in earnings, and that the inequality in earnings between skilled and unskilled workers increased during this period. This suggests that globalization has been associated with adverse labour market outcomes in Kenya. Copyright © 2004 John Wiley & Sons, Ltd. [source] | |||||||||||||