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Expeditious Synthesis (expeditious + synthesis)
Selected AbstractsExpeditious Syntheses of Conjugated Allenyl Esters and Oxazoles Through a Cascade Reaction of ,-Alkynyl Malonates under Alkaline Conditions.CHEMINFORM, Issue 28 2006Shigeki Sano Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] An Expeditious Synthesis of N -Acetylneuraminic Acid ,- C -Glycosyl Derivatives (",- C -Glycosides") from the Anomeric AcetatesEUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 19 2007Adeline Malapelle Abstract The reductive metallation of the readily available peracetylated derivatives of methyl N -acetylneuraminate 3a and 3b by samarium diiodide without any additive generates the corresponding anomeric samarium(III) organometallics. These intermediates react efficiently with carbonyl compounds under Barbier conditions, providing a fast synthesis of C -ketosides. The ,- and ,-acetates are equally effective, and excellent yields are obtained for coupling with cyclic ketones. The procedure has been conveniently applied to the synthesis of a C -ketoside of N -acetylneuraminic acid with an attached linker, ready to use as a building block in the elaboration of multivalent biological probes. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007) [source] ChemInform Abstract: Expeditious Synthesis of Highly Substituted Indolizinones via a Palladium-Catalyzed Domino Sequence.CHEMINFORM, Issue 43 2010Ikyon Kim Abstract Aminopalladation, reductive elimination and 1,2-shift allow the synthesis of a broad spectrum of indolizinones as an interesting pharmacophore from propargylic alcohols (I) and aryl iodides. [source] ChemInform Abstract: Expeditious Synthesis of Benzopyrans via Lewis Acid-Catalyzed C,H Functionalization: Remarkable Enhancement of Reactivity by an ortho Substituent.CHEMINFORM, Issue 34 2010Keiji Mori Abstract ortho-Substitution to the alkoxy group enhances the reactivity of the substrates and leads to the higher yields of the corresponding products [cf. [source] ChemInform Abstract: L-Proline-Catalyzed One-Pot Expeditious Synthesis of Highly Substituted Pyridines at Room Temperature.CHEMINFORM, Issue 29 2010Chhanda Mukhopadhyay Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: An Expeditious Synthesis and Anticancer Activity of Novel 4-(3,-Indolyl)oxazoles.CHEMINFORM, Issue 28 2010Dalip Kumar Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: An Expeditious Synthesis of 4-Fluoropiperidines via Aza-Prins Cyclization.CHEMINFORM, Issue 27 2010J. S. Yadav Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Expeditious Synthesis of 1,1-Diarylethylenes Related to Isocombretastatin A-4 (isoCA-4) via Palladium-Catalyzed Arylation of N-Tosylhydrazones with Aryl Triflates.CHEMINFORM, Issue 10 2010Bret Treguier Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Efficient and Expeditious Synthesis of Di- and Trisubstituted Thiazoles in PEG under Catalyst-Free Conditions.CHEMINFORM, Issue 5 2010Dongjian Zhu Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: First Expeditious Synthesis of 6,11-Diamino-[6]carbohelicenes.CHEMINFORM, Issue 50 2009Gregory Pieters Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: The First Ionic Liquid Promoted Three-Component Coupling Strategy for an Expeditious Synthesis of ,-Nitrocarbonitriles/Thiocyanates.CHEMINFORM, Issue 18 2009Lal Dhar S. Yadav Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: An Efficient and Expeditious Synthesis of Di- and Monosubstituted 2-Aminoimidazoles.CHEMINFORM, Issue 24 2008Chai Hoon Soh Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: An Expeditious Synthesis of Substituted Pyrrolidines and Tetrahydrofurans Starting from Baylis,Hillman Adducts.CHEMINFORM, Issue 10 2008Saravanan Gowrisankar Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Expeditious Synthesis of 3-Arylidenelactams and 3-Arylidenelactones from N-Tosylaziridine Derivatives.CHEMINFORM, Issue 26 2007Ka Young Lee Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Expeditious Synthesis of the Aromatic Spiroketal Skeleton Using Hetero-Diels,Alder Cycloaddition.CHEMINFORM, Issue 35 2006Guanglian Zhou Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Expeditious Synthesis of Sulfoazetidine spiro-C-Glycosides from Ketose Acetals.CHEMINFORM, Issue 22 2006Francisco J. Sayago Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Two Successive One-Pot Reactions Leading to the Expeditious Synthesis of (-)-Centrolobine.CHEMINFORM, Issue 50 2004Lucie Boulard Abstract For Abstract see ChemInform Abstract in Full Text. [source] An Expeditious Synthesis of a (3S,4S,5R)-Trihydroxyazepane.CHEMINFORM, Issue 52 2003Dilip D. Dhavale Abstract For Abstract see ChemInform Abstract in Full Text. [source] ChemInform Abstract: Microwave-Assisted Amination of Quinolone Carboxylic Acids: An Expeditious Synthesis of Fluoroquinolone Antibacterials.CHEMINFORM, Issue 50 2001P. Ganapati Reddy Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Ionic liquid catalyzed expeditious synthesis of 2-aryl-2,3-dihydroquinolin-4(1H)-ones and 2-aryl-2,3-dihydro-4H -chromen-4-ones under microwave irradiationJOURNAL OF HETEROCYCLIC CHEMISTRY, Issue 4 2009Dalip Kumar A facile and convenient synthesis of 2-aryl-2,3-dihydroquinolin-4(1H)-one and 2-aryl-2,3-dihydro-4H -chromen-4-one has been described using ionic liquid catalyzed intramolecular cyclization of the corresponding 2,-aminochalcones and 2,-hydroxychalcones, respectively. The rapid and fairly general protocol affords product in good yield. Ionic liquid, 1-butyl-3-methylimidazolium tetrafluoroborate, was recovered and reused without loosing its efficiency. J. Heterocyclic Chem., (2009) [source] ,-Oxoanilides in heterocyclic synthesis: An expeditious synthesis of new polyfunctionally substituted pyridine and pyrazole derivativesJOURNAL OF HETEROCYCLIC CHEMISTRY, Issue 6 2008A. M. Hussein 3-Oxo- N -{4-[(pyrimidin-2-ylamino)sulfonyl]phenyl}butanamide 3 was condensed with (DMF-DMA) in refluxing dry dioxane to yield branched structure 4 not its linear isomeric 5. Compound 4 readily reacted with active methylene to yield compounds 8a-c, 14, 17 and 20 respectively. Also enaminone 4 reacted with phenyl hydrazine giving 24 and 25. In contrast, when compound 4 reacted with hydrazine hydrate in the same experimental conditions pyrazole derivative 27 was obtained. Furthermore, condensation of anilide 3 with triethylorthoformate in refluxing acetic anhydride afforded the ethoxy methylene derivative 28. On the other hand, compound 28 was reacted with active methylene reagents, and hydrazines to afford the products identical in all respects (mp., mixed mp., and spectral data) with those corresponding to compounds 6-27 respectively. Similarly, compound 3 was reacted with hydrazine hydrate to afford the reaction product 29. Also, compound 3 reacted with cyanoacetamide in refluxing ethanolic pipridine solution to yield the pyridine derivative 30. Finally, 3 reacted with hydroxylamine hydrochloride in refluxing ethanol/sodium acetate solution to yield the acyclic oxime derivative 31. [source] Efficient synthesis of polyoxygenated flavones from naturally occurring flavanonesJOURNAL OF PHARMACY AND PHARMACOLOGY: AN INTERNATI ONAL JOURNAL OF PHARMACEUTICAL SCIENCE, Issue 12 2007Paolo Bovicelli Flavonoids are constituents of the human diet (they are present in many beverages and food), and in organisms they are responsible for several biological functions, including that of antioxidant. Because of the increasing interest in these molecules, methods for their synthesis and structural modification are of great importance; studies on the biological activities of many of these compounds are insufficient because of their scarcity and/or high cost. We have developed an expeditious synthesis of polyoxygenated flavones, starting from available and inexpensive flavanones, using a bromination-methoxylation procedure. A series of flavonoids that are not otherwise accessible can be prepared using this method. As an example, 3,-demethoxysudachitin, a limited flavone possessing antimicrobial activity against methicillin-resistant Staphylococcus aureus and Helicobacter pylori and acting as a 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenger, was prepared in fairly satisfactory yield. [source] | ||||||||||