Age Strata (age + stratum)

Distribution by Scientific Domains


Selected Abstracts


Sedimentary and crustal structure from the Ellesmere Island and Greenland continental shelves onto the Lomonosov Ridge, Arctic Ocean

GEOPHYSICAL JOURNAL INTERNATIONAL, Issue 1 2010
H. Ruth Jackson
SUMMARY On the northern passive margin of Ellesmere Island and Greenland, two long wide-angle seismic reflection/refraction (WAR) profiles and a short vertical incident reflection profile were acquired. The WAR seismic source was explosives and the receivers were vertical geophones placed on the sea ice. A 440 km long North-South profile that crossed the shelf, a bathymetric trough and onto the Lomonosov Ridge was completed. In addition, a 110 km long profile along the trough was completed. P -wave velocity models were created by forward and inverse modelling. On the shelf modelling indicates a 12 km deep sedimentary basin consisting of three layers with velocities of 2.1,2.2, 3.1,3.2 and 4.3,5.2 km s,1. Between the 3.1,3.2 km s,1 and 4.3,5.2 km s,1 layers there is a velocity discontinuity that dips seaward, consistent with a regional unconformity. The 4.3,5.2 km s,1 layer is interpreted to be Palaeozoic to Mesozoic age strata, based on local and regional geological constraints. Beneath these layers, velocities of 5.4,5.9 km s,1 are correlated with metasedimentary rocks that outcrop along the coast. These four layers continue from the shelf onto the Lomonosov Ridge. On the Ridge, the bathymetric contours define a plateau 220 km across. The plateau is a basement high, confirmed by short reflection profiles and the velocities of 5.9,6.5 km s,1. Radial magnetic anomalies emanate from the plateau indicating the volcanic nature of this feature. A lower crustal velocity of 6.2,6.7 km s,1, within the range identified on the Lomonosov Ridge near the Pole and typical of rifted continental crust, is interpreted along the entire line. The Moho, based on the WAR data, has significant relief from 17 to 27 km that is confirmed by gravity modelling and consistent with the regional tectonics. In the trough, Moho shallows eastward from a maximum depth of 19,16 km. No indication of oceanic crust was found in the bathymetric trough. [source]


Benefit of Adherence With Bisphosphonates Depends on Age and Fracture Type: Results From an Analysis of 101,038 New Bisphosphonate Users,,

JOURNAL OF BONE AND MINERAL RESEARCH, Issue 9 2008
Jeffrey R Curtis
Abstract The relationship between high adherence to oral bisphosphonates and the risk of different types of fractures has not been well studied among adults of different ages. Using claims data from a large U.S. health care organization, we quantified adherence after initiating bisphosphonate therapy using the medication possession ratio (MPR) and identified fractures. Cox proportional hazards models were used to evaluate the rate of fracture among nonadherent persons (MPR < 50%) compared with highly adherent persons (MPR , 80%) across several age strata and a variety of types of clinical fractures. In conjunction with fracture incidence rates among the nonadherent, these estimates were used to compute the number needed to treat with high adherence to prevent one fracture, by age and fracture type. Among 101,038 new bisphosphonate users, the proportion of persons with high adherence at 1, 2, and 3 yr was 44%, 39%, and 35%, respectively. Among 65- to 78-yr-old persons with a physician diagnosis of osteoporosis, the crude and adjusted rate of hip fracture among the nonadherent was 1.96 (95% CI, 1.48,2.60) and 1.74 (95% CI, 1.30,2.31), respectively, resulting in a number needed to treat with high adherence to prevent one hip fracture of 107. The impact of high adherence was substantially less for other types of fractures and for younger persons. Analysis of adherence in a non,time-dependent fashion artifactually magnified differences in fracture rates between adherent and nonadherent persons. The antifracture effectiveness associated with high adherence to oral bisphosphonates varied substantially by age and fracture type. These results provide estimates of absolute fracture effectiveness across age subgroups and fracture types that have been minimally evaluated in clinical trials and may be useful for future cost-effectiveness studies. [source]


Dental nomograms for benchmarking based on the study of health in Pomerania data set

JOURNAL OF CLINICAL PERIODONTOLOGY, Issue 12 2004
C. Schwahn
Abstract Aim: Benchmarking is a means of setting goals or targets. On an oral health level, it denotes retaining more teeth and/or improving the quality of life. The goal of this pilot investigation was to assess whether the data generated by a population-based study (SHIP 0) can be used as a benchmark data set to characterize different practice profiles. Material and Methods: The data collected in the population-based study SHIP (n=4310) in eastern Germany were used to generate nomograms of tooth loss, attachment loss, and probing depth. The nomograms included twelve 5-year age strata (20,79 years) presented as quartiles, and additional percentiles of the dental parameters for each age group. Cross-sectional data from a conventional dental office (n=186) and from a periodontology unit (n=130, Greifswald) in the study region as well as longitudinal data set of a another periodontology unit (n=135, Kiel) were utilized in order to verify whether the given practice profile was accurately reflected by the nomogram. Results: In terms of tooth loss, the data from the conventional dental office agree with the median from the nomogram. For attachment loss and probing depth, some age groups yielded slight but not uniform deviations from the median. Cross-sectional data from the periodontology unit Greifswald showed attachment loss higher than the median in younger but not in older age groups. The probing depth was uniformly less than the median and tended toward the 25th percentile with increasing age. The longitudinal data of the Unit of Periodontology in Kiel showed a pronounced trend towards higher percentiles of residual teeth, meaning that the patients retained more teeth. Conclusion: The profile of the Pomeranian dental office does not deviate noticeably from the population-based nomograms. The higher attachment loss of the Unit of Periodontology in Greifswald in younger age strata clearly reflects their selection because of periodontal disease; the combination of higher attachment loss and decreased probing depth may reflect the success of the treatment. The tendency of attachment loss towards the median with increasing age may indicate that the Unit of Periodontology in Greifswald does not fulfill its function as a special care unit in the older subjects. The longitudinal data set of the Unit of Periodontology in Kiel impressively reflects the potential of population-based data sets as a means for benchmarking. Thus, nomograms can help to determine the practice profile, potentially yielding benefits for the dentist, health insurance company, or , as in the case of the special care unit , public health research. [source]


Multidrug intravenous anesthesia for children undergoing MRI: a comparison with general anesthesia

PEDIATRIC ANESTHESIA, Issue 12 2007
AHMED A. SHORRAB MD
Summary Background:, We used a multidrug intravenous anesthesia regimen with midazolam, ketamine, and propofol to provide anesthesia for children during magnetic resonance imaging (MRI). This regimen was compared with general anesthesia in a randomized comparative study. Outcome measures were safety, side effects and recovery variables in addition to adverse events in relation to age strata. Methods:, The children received either general anesthesia with propofol, vecuronium and isoflurane [general endotracheal anesthesia (GET) group; n = 313] or intravenous anesthesia with midazolam, ketamine, and propofol [intravenous anesthesia (MKP) group; n = 342]. Treatment assignment was randomized based on the date of the MRI. Physiological parameters were monitored during anesthesia and recovery. Desaturation (SpO2 < 93%), airway problems, and the need to repeat the scan were recorded. The discharge criteria were stable vital signs, return to baseline consciousness, absence of any side effects, and ability to ambulate. Results:, With the exception of two children (0.6%) in the MKP group, all enrolled children completed the scan. A significantly greater number (2.3%) required a repeat scan in the MKP group (P < 0.05) and were sedated with a bolus dose of propofol. The total incidence of side effects was comparable between the MKP (7.7%) and GET groups (7.0%). Infants below the age of 1 year showed a significantly higher incidence of adverse events compared with the other age strata within each group. Within the MKP group, risk ratio was 0.40 and 0.26 when comparing infants aged below 1 year with the two older age strata, respectively. Recovery characteristics were comparable between both groups. Conclusions:, Intravenous midazolam, ketamine and propofol provides safe and adequate anesthesia, comparable with that obtained from general endotracheal anesthesia, for most children during MRI. [source]


Sexlessness among Married Chinese Adults in Hong Kong: Prevalence and Associated Factors

THE JOURNAL OF SEXUAL MEDICINE, Issue 11 2009
Jean H. Kim ScD
ABSTRACT Introduction., Despite recent media coverage in the topic of sexless marriages in East Asia, population-based studies examining the absence of sexual activity among nonelderly married individuals are scant. Previous studies have not simultaneously examined sociodemographic, physiological, and lifestyle predictors of sexless marriages. Aims., To determine the prevalence of past-year sexlessness and the associated factors among the married Chinese adults in Hong Kong. Methods., An anonymous, population-based telephone survey was conducted on 2,846 married Chinese men and women between the ages of 25 and 59 in Hong Kong. Main Outcome Measures., The prevalence of past-year sexlessness and the associated factors and mental health symptoms were examined. Results., The prevalence of past-year sexlessness between the ages of 25,34 years, 35,44 years and 45,59 years was 5.5, 5.1, and 17.0%, respectively, among married males, and 8.3, 12.4, and 31.6%, respectively, among married females. Older age and poor spousal relationship were associated with sexlessness for females, whereas lack of interest in sex, older age, and lower education were significant factors for males. Married women demonstrated statistically significant associations between sexlessness and poorer mental health indicators, such as lower quality of life and being bothered by the unavailability of a sex partner. Conclusions., Sexlessness is prevalent among certain subgroups of urban Chinese couples in Hong Kong, and the large discrepancy in sexlessness between married men and women in each age strata suggests a high prevalence of extramarital relationships. Contrary to commonly held beliefs, there was a stronger association between sexlessness and poorer psychosocial symptoms among married females than males. Sexless marriages are an underappreciated phenomenon among urban Chinese individuals. Kim JH, Lau JTF, and Cheuk KK. Sexlessness among married Chinese adults in Hong Kong: Prevalence and associated factors. J Sex Med 2009;6:2997,3007. [source]


Overactive Bladder Is Associated with Erectile Dysfunction and Reduced Sexual Quality of Life in Men

THE JOURNAL OF SEXUAL MEDICINE, Issue 12 2008
Debra E. Irwin MSPH
ABSTRACT Introduction., The prevalence of sexual dysfunction, including erectile dysfunction (ED), is greater in men with lower urinary tract symptoms (LUTS), including overactive bladder (OAB), than in men without LUTS. Aim., To evaluate the prevalence of ED, the impact of urinary symptoms on sexual activity and sexual enjoyment, and sexual satisfaction in men with OAB. Methods., A nested case-control analysis was performed on data from a subset of men with (cases) and without (controls) OAB frequency-matched for age (5-year age strata) and country from the EPIC study. Respondents were asked about OAB symptoms (using the 2002 International Continence Society [ICS] definitions) and sexual activity. Sexually active respondents were asked about ED, sexual enjoyment, and overall satisfaction with their sex lives. Conditional logistic regression was used to assess factors associated with ED. Main Outcome Measures., The percentage of cases and controls reporting ED, a reduction in the frequency of sexual activity or enjoyment of sexual activity because of urinary symptoms, and overall satisfaction with their sex lives was determined for cases and controls. Results., A total of 502 cases and 502 controls were matched for age strata and country. Significantly more cases (14%) reported reduced sexual activity because of urinary symptoms compared with controls (4%; P , 0.05). Among sexually active respondents, cases were significantly more likely to have ED than were controls (prevalence odds ratio, 1.5; 95% confidence interval, 1.1,2.2); the prevalence of ED was similar to that for men with hypertension or diabetes. Significantly more cases (15%) reported decreased enjoyment of sexual activity because of urinary symptoms relative to controls (2%; P , 0.05), and significantly fewer cases were satisfied with their sex lives (81% vs. 90%; P , 0.05). Conclusions., OAB, as defined by the ICS, was significantly associated with increased prevalence of ED, reduced sexual activity and sexual enjoyment because of urinary symptoms, and reduced sexual satisfaction. Irwin DE, Milson I, Reilly K, Hunskaar S, Kopp Z, Herschorn S, Coyne KS, Kelleher CJ, Artibani W, and Abrams P. Overactive bladder is associated with erectile dysfunction and reduced sexual quality of life in men. J Sex Med **;**:**,**. [source]