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Selected AbstractsProperties and applications of supports for enzyme-mediated transformations in solid phase synthesisJOURNAL OF CHEMICAL TECHNOLOGY & BIOTECHNOLOGY, Issue 10 2006Alessandra Basso Abstract With the increasing interest in automated synthesis and screening protocols, solid supported chemistry and biochemistry have become attractive technologies. Furthermore, the use of enzymes in solid phase synthesis has opened the route to selective and mild processes. The efficiency of enzymes in transforming substrates that are bound on solid supports is strictly related to the availability of polymers endowed with specific properties, above all permeability to enzymes. This review describes how the recent developments of this rapidly evolving area have made possible novel challenging applications of enzymes in solid phase synthesis. Copyright © 2006 Society of Chemical Industry [source] Nurse-led discharge from high dependency unitNURSING IN CRITICAL CARE, Issue 2 2003Gillian Knight Summary ,High dependency care is a rapidly evolving area of critical care, with high patient turnover, which ultimately leads to high levels of pressure for beds ,There is a growing trend emerging, recognizing the importance and value of nurse-led initiatives in delivering effective nursing care in acute care settings ,One specific nurse-led initiative this author has developed is that of nurse-led discharge (NLD) from the high dependency unit (HDU), in order to optimize the utilization of critical care beds within the HDU ,An audit of the current practice was undertaken, which ultimately led to the implementation of NLD ,Early experiences indicate that HDU beds are now being used more effectively [source] Computational Biology: Toward Deciphering Gene Regulatory Information in Mammalian GenomesBIOMETRICS, Issue 3 2006Hongkai Ji Summary Computational biology is a rapidly evolving area where methodologies from computer science, mathematics, and statistics are applied to address fundamental problems in biology. The study of gene regulatory information is a central problem in current computational biology. This article reviews recent development of statistical methods related to this field. Starting from microarray gene selection, we examine methods for finding transcription factor binding motifs and cis -regulatory modules in coregulated genes, and methods for utilizing information from cross-species comparisons and ChIP-chip experiments. The ultimate understanding of cis -regulatory logic in mammalian genomes may require the integration of information collected from all these steps. [source] Instrumental analysis of gas hydrates propertiesASIA-PACIFIC JOURNAL OF CHEMICAL ENGINEERING, Issue 2 2010Y. Rojas Abstract Gas hydrates attracted intense research interest when it was first recognised some 70 years ago that they were responsible for the blockage of flow lines, valves and well heads, thereby causing great loss of production and other severe safety hazards to the oil and gas industry. After many decades, these compounds are still the topic of research activities in various multi-disciplinary fields, including chemical and petroleum engineering, earth and geophysics, chemistry and environmental sciences. This is not only due to the great impact that these compounds have on the oil and gas industry, but also to the potential applications they have in many evolving areas, including, but not only, natural gas storage and transportation, carbon dioxide sequestration, and sea-water desalination. It is generally accepted that gas hydrates represent the largest source of hydrocarbons on earth, something which has not been appreciated until only recently. Management, either prevention or application or both, of gas hydrates requires a complete knowledge and understanding of the formation, decomposition and inhibition mechanisms of gas hydrates, which in turn demands advanced experimental methods and instrumental techniques for gas hydrate characterisation. This paper reviews a broad range of techniques that have been used for natural gas hydrate characterisation. It includes the basic physical science principles of each method and the gas hydrate properties that each method is capable of detecting, including some modern instrumental analyses that enable direct determination of gas hydrate phases and possible measurement of molecular interactions within the fluid phases. Copyright © 2009 Curtin University of Technology and John Wiley & Sons, Ltd. [source] | ||||||||||