Agricultural Pesticides (agricultural + pesticide)

Distribution by Scientific Domains


Selected Abstracts


Relocated Citizens' Perceptions and Attitudes Regarding Indoor Application of Toxic Agricultural Pesticides

JOURNAL OF CONTINGENCIES AND CRISIS MANAGEMENT, Issue 3 2000
Olurominiyi O. Ibitayo
This study investigates the viewpoints of relocated citizens regarding the effects of relocation, perceptions of the potential hazards of indoor application of a toxic agricultural pesticide , methyl parathion , and the efficacy of the risk information emphasizing the adverse health effects of this inappropriate use of the pesticide. The surveyed citizens were those relocated because the levels of the pesticide contaminant in their homes were high. Despite the extensive information , through the mass media and face-to-face warnings and activities such as assessment of contamination levels, decontamination of homes and relocation , the respondents, regardless of race, consistently perceived relatively low levels of risks from the indoor application of methyl parathion. The disruption of family life, loss of peace of mind and the loss of contaminated property were the most mentioned problems caused by the relocation. In contrast to past research, the disruption of social ties or networks was hardly mentioned. The results of this study suggest that the perceived personal benefits of home-use of methyl parathion, and the voluntariness and controllability of exposure may have been the overriding factors of the respondents' risk perception, more than the clarity, content, consistency, and credibility of the risk information. The fact that the relocation was temporary must have contributed to the low level of importance attached by the respondents to the disruption of social ties as one of the adverse effects of the relocation. [source]


Agricultural pesticides and selected degradation products in five tidal regions and the main stem of Chesapeake Bay, USA

ENVIRONMENTAL TOXICOLOGY & CHEMISTRY, Issue 12 2007
Laura L. McConnell
Abstract Nutrients, sediment, and toxics from water sources and the surrounding airshed are major problems contributing to poor water quality in many regions of the Chesapeake Bay, an important estuary located in the mid-Atlantic region of the United States. During the early spring of 2000, surface water samples were collected for pesticide analysis from 18 stations spanning the Chesapeake Bay. In a separate effort from July to September of 2004, 61 stations within several tidal regions were characterized with respect to 21 pesticides and 11 of their degradation products. Three regions were located on the agricultural Delmarva Peninsula: The Chester, Nanticoke, and Pocomoke Rivers. Two regions were located on the more urban western shore: The Rhode and South Rivers and the Lower Mobjack Bay, including the Back and Poquoson Rivers. In both studies, herbicides and their degradation products were the most frequently detected chemicals. In 2000, atrazine and metolachlor were found at all 18 stations. In 2004, the highest parent herbicide concentrations were found in the upstream region of Chester River. The highest concentration for any analyte in these studies was for the ethane sulfonic acid of metolachlor (MESA) at 2,900 ng/L in the Nanticoke River. The degradation product MESA also had the greatest concentration of any analyte in the Pocomoke River (2,100 ng/L) and in the Chester River (1,200 ng/L). In the agricultural tributaries, herbicide degradation product concentrations were more strongly correlated with salinity than the parent herbicides. In the two nonagricultural watersheds on the western shore, no gradient in herbicide concentrations was observed, indicating the pesticide source to these areas was water from the Bay main stem. [source]


Relocated Citizens' Perceptions and Attitudes Regarding Indoor Application of Toxic Agricultural Pesticides

JOURNAL OF CONTINGENCIES AND CRISIS MANAGEMENT, Issue 3 2000
Olurominiyi O. Ibitayo
This study investigates the viewpoints of relocated citizens regarding the effects of relocation, perceptions of the potential hazards of indoor application of a toxic agricultural pesticide , methyl parathion , and the efficacy of the risk information emphasizing the adverse health effects of this inappropriate use of the pesticide. The surveyed citizens were those relocated because the levels of the pesticide contaminant in their homes were high. Despite the extensive information , through the mass media and face-to-face warnings and activities such as assessment of contamination levels, decontamination of homes and relocation , the respondents, regardless of race, consistently perceived relatively low levels of risks from the indoor application of methyl parathion. The disruption of family life, loss of peace of mind and the loss of contaminated property were the most mentioned problems caused by the relocation. In contrast to past research, the disruption of social ties or networks was hardly mentioned. The results of this study suggest that the perceived personal benefits of home-use of methyl parathion, and the voluntariness and controllability of exposure may have been the overriding factors of the respondents' risk perception, more than the clarity, content, consistency, and credibility of the risk information. The fact that the relocation was temporary must have contributed to the low level of importance attached by the respondents to the disruption of social ties as one of the adverse effects of the relocation. [source]


Cytogenetic damage in female Chilean agricultural workers exposed to mixtures of pesticides

ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, Issue 1 2005
Carolina Márquez
Abstract The VIII Region of Bío-Bío is a major fruit-growing area of Chile that makes intensive use of agricultural pesticides. The cytogenetic damage associated with exposure to mixtures of pesticides was evaluated by comparing peripheral blood lymphocyte micronucleus (MN) frequencies in a group of 64 female agricultural workers and 30 female controls. The exposed subjects worked during the spring and summer in thinning and pruning fruit trees and in harvesting and packing different fruits, such as raspberries, grapes, apples, and kiwis. They did not use any protective measures during their work activities. A significant increase in the frequency of binucleated cells with micronuclei (BNMN) was found in the exposed women as compared with the controls (36.94 ± 14.47 vs. 9.93 ± 6.17 BNMN/1000 BN cells; P < 0.001). The frequency of BNMN varied as a function of age in both the exposed and control groups, but no correlation was found between BNMN frequency and the duration of exposure. Also, smoking and other habits had no effect on MN frequency. Our study confirms that occupational exposure to pesticide mixtures results in cytogenetic damage. Environ. Mol. Mutagen., 2005. © 2004 Wiley-Liss, Inc. [source]


Cell-cycle deregulation in BALB/c 3T3 cells transformed by 1,2-dibromoethane and folpet pesticides

ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, Issue 5 2003
Maria Alessandra Santucci
Abstract The cell-transforming potential of 1,2-dibromoethane and folpet, two widely used agricultural pesticides that are potential sources of environmental pollution, has been previously ascribed to their promoting activity. In this study, we investigated whether BALB/c 3T3 transformation by these chemicals was associated with the deregulation of signals involved in cell-cycle progression and in cell-cycle checkpoint induction. We found that two BALB/c 3T3 cell clones transformed by in vitro medium-term (8-week) exposure to the carcinogens had a constitutive acceleration of cell transition from G1 to S phase and an abrogation of the radiation-induced G1/S checkpoint. These events involved multiple signals; in particular, the inhibitors of cyclin/cyclin-dependent kinase complexes p21 and p27 were significantly down-modulated and the positive regulators of cell-cycle progression cyclin D3 and E were up-modulated. As anticipated for cells where the G1/S checkpoint was abrogated, the transformed cells exhibited a significant reinforcement of the radiation-induced G2/M checkpoint, the only checkpoint remaining to protect genomic integrity. However, cyclin A1 and B1 coexpression and cyclin A1 overexpression were found despite the G2 arrest in irradiated cells and these signals likely attenuate the G2/M checkpoint. These alterations to normal cell cycling may promote the emergence of both numerical and structural chromosomal abnormalities and their tolerance. Such a condition could play a key role in neoplastic transformation and be crucial in tumor progression. Furthermore, cyclin A1 overexpression may play an autonomous role in the neoplastic transformation of BALB/c 3T3 cells, as it does in other cell types of mesenchymal origin. Environ. Mol. Mutagen. 41:315,321, 2003. © 2003 Wiley-Liss, Inc. [source]


Evaluating acute toxicity of methyl parathion application in constructed wetland mesocosms,

ENVIRONMENTAL TOXICOLOGY, Issue 5 2004
C. D. Milam
Abstract Wetland ecosystems have reduced ambient levels of various organic and metallic compounds, although their effectiveness on agricultural pesticides is not well documented. Five stations within each of two 10 × 50 m constructed wetlands (two vegetated, two nonvegetated) were selected to measure the fate and effects of methyl parathion (MeP). Following a simulated storm event (0.64 cm of rainfall), aqueous, sediment, and plant samples were collected and analyzed spatially (5, 10, 20, and 40 m from the inlet) and temporally (after 3,10 days) for MeP concentrations and for the impact of those concentrations on the aquatic fauna. Aqueous toxicity to fish decreased spatially and temporally in the vegetated mesocosm. Pimephales promelas survival was significantly reduced, to 68%, at the 10-m station of the nonvegetated wetlands (3 h postapplication), with pesticide concentrations averaging 9.6 ,g MeP/L. Ceriodaphnia in both the vegetated and nonvegetated wetlands was sensitive (i.e., a significant acute response to MeP occurred) to pesticide concentrations through 10 days postapplication. Mean MeP concentrations in water ranged from 0.5 to 15.4 ,g/L and from 0.1 to 27.0 ,g/L in the vegetated and nonvegetated wetlands, respectively. Hyalella azteca aqueous tests resulted in significant mortality in the 5-m vegetated segment 10 days after exposure to MeP (2.2 ,g/L). Solid-phase (10-day) sediment toxicity tests showed no significant reduction in Chironomus tentans survival or growth, except for the sediments sampled 3 h postapplication in the nonvegetated wetland (65% survival). Thereafter, midge survival averaged >87% in sediments sampled from both wetlands. These data suggest that wetlands play a significant role in mitigating the effect of MeP exposure in sensitive aquatic biota. © 2004 Wiley Periodicals, Inc. Environ Toxicol 19: 471,479, 2004. [source]


Epoxiconazole causes changes in testicular histology and sperm production in the Japanese quail (Coturnix coturnix japonica)

ENVIRONMENTAL TOXICOLOGY & CHEMISTRY, Issue 11 2008
Konstanze Grote
Abstract The fungicide epoxiconazole (Epox), a triazole, belongs to the group of azole compounds that are extensively used as fungicides in various fruit crops. The frequent use of agricultural lands for wintering by migrating birds can be the source of their increased dietary intake of agricultural pesticides. We investigated whether exposure to Epox causes effects on avian fertility and reproduction, using the Japanese quail (Coturnix coturnix japonica) as a model species for the assessment of reproductive effects of pesticides in wild birds. Epox was administered to adult Japanese quail for three weeks at dietary levels of 10, 50, and 500 ppm, and possible effects on reproduction were investigated. Epox administration resulted in a significantly decreased number of spermatids in the 50- and 500-ppm dose groups. Histopathology showed a reduced number of testicular canaliculi with visible germ cells and a reduction in spermatid number. However, testis weight was not affected up to the highest dose level. No impact was observed on hormone levels, fertility, and reproductive outcome, as laying rate and percentage of fertile eggs were not altered. Likewise, treatment had no influence on the egg or chick parameters evaluated. A time- and dose-related transfer of Epox into the eggs was determined in all treatment groups. We conclude that dietary treatment of Japanese quail with 50 and 500 ppm of the triazole fungicide Epox resulted in a clear impact on the testis. The evaluation of the additional endpoints spermatid count and testicular histology have proven useful and are recommended for future studies on avian reproduction. [source]


Burrowing owls and agricultural pesticides: Evaluation of residues and risks for three populations in California, USA

ENVIRONMENTAL TOXICOLOGY & CHEMISTRY, Issue 2 2000
Jennifer A. Gervais
Abstract We examined selenium, organophosphorus, and organochlorine pesticide residues in egg, footwash, and feather samples from burrowing owls in three populations in central and southern California. Eggs from all sites contained detectable levels of p,p,-dichlorodiphenyldichloroethylene, with the San Joaquin Valley site containing up to 33 ,g/g (geometric mean x¯ = 7.52). Only low levels of polychlorinated biphenyls were detected, however (geometric mean x¯ = 1.98, n = 2). Selenuim concentrations were low in all samples (geometric mean x¯ = 0.426, n = 20). Eggshells collected in 1996 were 22% thinner than eggs collected prior to 1937. In addition, feather samples contained low levels of dichlorodiphenyldichloroethylene, and footwash samples indicated exposure to the pesticide chlorpyrifos. Pesticide-use records indicated that one population might also be at risk from applications of aldicarb near nests during the breeding season. [source]


Semen quality in fertile US men in relation to geographical area and pesticide exposure

INTERNATIONAL JOURNAL OF ANDROLOGY, Issue 1 2006
Shanna H. Swan
Summary We conducted the first US study to compare semen quality among study centres using standardized methods and strict quality control. We present data on semen quality in partners of 493 pregnant women recruited through prenatal clinics in four US cities during 1999,2001. Sperm concentration, semen volume and motility were determined at the centres and morphology was assessed at a central laboratory. While between-centre differences in sperm morphology and sample volume were small, sperm concentration and motility were significantly reduced in Columbia, MO (MO) relative to men in New York, NY, Minneapolis, MN and Los Angeles, CA; total number of motile sperm was 113 × 106 in MO and 162, 201 and 196 × 106 in CA, MN and NY respectively. Differences among centres remained significant in multivariate models that controlled for abstinence time, semen analysis time, age, race, smoking, history of sexually transmitted disease and recent fever (all p -values <0.01). We hypothesized that poorer sperm concentration and motility in MO men relative to other centres might be related to agricultural pesticides that are commonly used in the mid-west. We investigated this hypothesis by conducting a nested case,control study within the MO cohort. We selected 25 men in this cohort for whom all semen parameters (concentration, % normal morphology and % motile) were low as cases and an equal number of men for whom all semen parameters were within normal limits as controls. We measured metabolites of eight non-persistent, current-use pesticides in urine samples the men had provided at the time of semen collection. Pesticide metabolite levels were elevated in cases compared with controls for the herbicides alachlor and atrazine, and for the insecticide diazinon (2-isopropoxy-4-methyl-pyrimidinol) (p -values for Wilcoxon rank test = 0.0007, 0.012, and 0.0004 for alachlor, atrazine and diazinon respectively). Men with higher levels of alachlor or diazinon were significantly more likely to be cases than men with low levels [odds ratios (OR) = 30.0, 16.7 for alachlor and diazinon respectively], as were men with atrazine over the limit of detection (OR = 11.3). These associations between current-use pesticides and reduced semen quality suggest that agricultural chemicals may have contributed to the reduced semen quality seen in fertile men from mid-Missouri. [source]


Pesticide use and colorectal cancer risk in the agricultural health study

INTERNATIONAL JOURNAL OF CANCER, Issue 2 2007
Won Jin Lee
Abstract We investigated the relationship between agricultural pesticides and colorectal cancer incidence in the Agricultural Health Study. A total of 56,813 pesticide applicators with no prior history of colorectal cancer were included in this analysis. Detailed pesticide exposure and other information were obtained from self-administered questionnaires completed at the time of enrollment (1993,1997). Cancer incidence was determined through population-based cancer registries from enrollment through December 31, 2002. A total of 305 incident colorectal cancers (212 colon, 93 rectum) were diagnosed during the study period, 1993,2002. Although most of the 50 pesticides studied were not associated with colorectal cancer risk, chlorpyrifos use showed significant exposure response trend (p for trend = 0.008) for rectal cancer, rising to a 2.7-fold (95% confidence interval: 1.2,6.4) increased risk in the highest exposure category. Aldicarb was associated with a significantly increased risk of colon cancer (p for trend = 0.001), based on a small number of exposed cases, with the highest exposure category resulting in a 4.1-fold increased risk (95% confidence interval: 1.3,12.8). In contrast, dichlorophenoxyacetic acid showed a significant inverse association with colon cancer but the association was not monotonic. Our findings should be interpreted cautiously since the literature suggesting that pesticides are related to colorectal cancer is limited. Nonetheless the possibility of an association between exposure to certain pesticides and incidence of colorectal cancer among pesticide applicators deserves further evaluation. © 2007 Wiley-Liss, Inc. [source]


Use of models to assess the reduction in contamination of water bodies by agricultural pesticides through the implementation of policy instruments: a case study of the Voluntary Initiative in the UK

PEST MANAGEMENT SCIENCE (FORMERLY: PESTICIDE SCIENCE), Issue 12 2006
James Garratt
Abstract Through normal agricultural use, pesticides may reach environmental water bodies via several routes of entry. Various policies and initiatives exist to reduce the effects of pesticides in the environment. One such initiative in place in the UK is the Voluntary Initiative (VI). The VI is a voluntary scheme put forward by the Crop Protection Association with other crop protection and farming organisations to reduce the environmental impacts of pesticides. Mathematical models of pesticide fate can usefully be applied to examine the impact of factors influencing the contamination of water bodies by pesticides. The work reported here used water quality models to examine how changes in farmer behaviour could potentially impact pesticide contamination of environmental water bodies. As far as possible, uncalibrated, standard regulatory models were used. Where suitable models were not available, simple models were defined for the purposes of the study and calibrated using literature data. Scenarios were developed to represent different standards of practice with respect to pesticide user behaviour. The development of these scenarios was guided by the Crop Protection Management Plan (CPMP) aspect of the VI. A framework for the use of modelling in the evaluation of the VI is proposed. The results of the modelling study suggest that, in several areas, widespread adoption of the measures proposed in the VI could lead to reductions in pesticide contamination of environmental water bodies. These areas include pesticide contamination from farmyards, spray drift and field runoff. In other areas (including pesticide leaching to groundwater and contamination of surface water from field drains) the benefits that may potentially be gained from the VI are less clear. A framework to evaluate the VI should take into consideration the following aspects: (1) groundwater is more at risk when there is a combination of leachable compounds, vulnerable soils, shallow groundwater and high product usage; (2) surface water contamination from drains is most likely when heavy rain falls soon after application, the soils are vulnerable and product usage is high; (3) surface water contamination from drift is most likely when the distance between the spray boom and water body is small and product usage is high; (4) surface water contamination from farmyards is dependent on the nature of the farmyard surface, the competence of the spray operator and the level of product usage. Any policy or initiative to reduce pesticide contamination should be measured against farmer behaviour in these areas. © Crown copyright 2006. Reproduced with the permission of Her Majesty's Stationery Office. Published by John Wiley & Sons, Ltd. [source]