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Emerging Technology (emerging + technology)
Selected AbstractsCommentary: The federal ,Prenatally and Postnatally Diagnosed Conditions Awareness Act'PRENATAL DIAGNOSIS, Issue 9 2009Philip R. Reilly Abstract The recently enacted federal law, the ,Prenatally and Postnatally Diagnosed Conditions Awareness Act' (United States Public Law 110,374) seeks to improve opportunities for parents and pregnant women to anticipate and understand the likely life course of children born with Down syndrome and other (unspecified) conditions. The law is in part a response to the continued growth of prenatal screening and testing. For example, the American College of Obstetricians and Gynecologists' Practice Bulletin 77 recommends that ,Screening and invasive diagnostic testing for aneuploidies be available to all women who present for prenatal care before 20 weeks of gestation regardless of maternal age.' Emerging technologies anticipate an era in which the scope of prenatal screening and testing will be much larger than it is today. Inevitably, more women will find themselves facing the hard question of whether to continue or end a pregnancy in which a fetus has been found to have a significant abnormality. While the new federal law is not likely to have a major impact on obstetric practice, it may be a harbinger of renewed wide-scale public debate concerning the ethics of prenatal screening. Copyright © 2009 John Wiley & Sons, Ltd. [source] Subclinical Atherosclerosis: Evolving Role of Carotid Intima-Media ThicknessPREVENTIVE CARDIOLOGY, Issue 4 2010FRCPC, Farouk Mookadam MD Cardiovascular risk factors have utility in risk prediction but have limitations in predicting individual risk. Identifying an individual's risk remains a challenge. Emerging technologies such as carotid artery ultrasonography and measures of carotid intima-media thickness (CIMT) may be useful in identifying the susceptible patient who may benefit from more aggressive preventive therapy. This screening test is noninvasive, reproducible, inexpensive, and radiation-free. Recent data have improved our understanding of the application of CIMT as a screening tool for cardiovascular disease. CIMT measurement may place an individual into a higher- or lower-risk category, allowing for appropriate institution of preventive strategies. Prev Cardiol. 2010;13:186,197.©2010 Wiley Periodicals, Inc. [source] Ovarian cancer proteomics: Many technologies one goalPROTEOMICS - CLINICAL APPLICATIONS, Issue 2 2008Kothandaraman Narasimhan Abstract The last decade has seen major changes in the technologies used to identify markers for diagnosing cancer. This review focuses on recent developments on the evolving field of biomarker discovery, and validation techniques using proteomics platforms for ovarian cancer. It is possible now to diagnose various disease conditions using microliter quantities of body fluids. Currently the major developments were made in three distinct areas: (i) protein profiling, (ii) high-throughput validation techniques, and (iii) solid and liquid phase protein microarray platforms for analyzing candidate markers across subclasses and stages of cancers. The recent addition to the long list of technologies is metabolomics using metabolite profiling and informatics-based filtering of information for biomarker discovery of ovarian cancer. Emerging technologies need to address ways to eliminate the limitations posed by the complex dynamic nature of body fluids as well as ways to enrich low-abundance tumor markers if they were to become a successful biomarker discovery tool. These new technologies hold significant promise in identifying more robust markers for ovarian cancer. Since the prevalence of this disease in the population is low, the test must have a high specificity. [source] The molecular journey from ductal carcinoma in situ to invasive breast cancerCANCER, Issue 10 2008Lisa Wiechmann MD Abstract Ductal carcinoma in situ (DCIS) accounts for approximately 20% of mammographically detected breast cancers. DCIS can recur or progress to invasive breast cancer, but the ability to predict the outcome of patients with DCIS remains limited, leading to inappropriate treatment choices. To the authors' knowledge to date, the hunt for molecular prognostic markers for DCIS has been unsuccessful. Emerging technologies, however, are shedding new light on the biologic course of DCIS. In the current study, the authors review recent findings elucidating the molecular journey from DCIS to invasive cancer and discuss how these findings will lead to more effective treatment with minimization of morbidity. Cancer 2008. © 2008 American Cancer Society. [source] Professional and economic factors affecting access to mammography: A crisis today, or tomorrow?,CANCER, Issue 3 2005Results from a national survey Abstract BACKGROUND Objective data and anecdotal reports have suggested that access to mammography may be declining because of facility closures and difficulty in recruiting and retaining radiologists and radiologic technologists. To gain insight into the practice patterns, use of emerging technologies, and concerns of breast imagers in current practice, the Society of Breast Imaging (SBI) conducted a national survey of breast imaging practices in the U.S. METHODS Between October 2003 and April 2004, the SBI conducted a survey of the SBI membership database, and received completed surveys from 575 breast imaging practices in the U.S. Responses to the survey regarding practice characteristics, the utilization of standard and emerging technologies, staffing, malpractice, finance, and morale were analyzed. RESULTS Job vacancies for radiologists who read mammograms were reported in 163 practices (29%), 59 of which (10%) had 2 or more openings. A higher proportion of practices with job openings had long appointment waiting times for asymptomatic women when compared with fully staffed practices. Unfilled fellowship positions also were common, with 41 of 65 practices that offer fellowships reporting 47 openings. Among 554 responding practices, 55% reported that someone in their practice was sued because of a mammography related case within the past 5 years, and 50% of practices reported that the threat of lawsuits made radiologist staffing "moderately" or "a lot" more difficult. Of 521 responding practices, 35% reported financial losses in 2002. One in 5 respondents reported that they would prefer to spend less time in mammography, and fewer than 1 in 3 would recommend a breast imaging fellowship to a relative or friend. Emerging technologies, such as breast magnetic resonance imaging and screening ultrasound, currently are being performed in many practices. CONCLUSIONS The survey results provide support for anecdotal reports that breast imaging practices face significant challenges and stresses, including shortages of key personnel, a lack of trainees, malpractice concerns, financial constraints, increased workload due to emerging technologies, low appeal of breast imaging as a career specialty, and the steady rise in the population of women of screening age. Cancer 2005. © 2005 American Cancer Society. [source] Long-term study of a portable field robot in urban terrainJOURNAL OF FIELD ROBOTICS (FORMERLY JOURNAL OF ROBOTIC SYSTEMS), Issue 8-9 2007Carl Lundberg The armed forces have a considerable amount of experience in using robots for bomb removal and mine clearing. Emerging technology also enables the targeting of other applications. To evaluate if real deployment of new technology is justified, tactical advantages gained have to be compared to drawbacks imposed. Evaluation calls for realistic tests which in turn require methods dictating how to deploy the new features. The present study has had two objectives: first, to gain a comprehensive view of a potential user of man-portable robots; second, to embed a robot system with users for assessment of present technology in real deployment. In this project we investigated an army company specialized in urban operations performing their tasks with the support of the iRobot Packbot Scout. The robot was integrated and deployed as an ordinary piece of equipment which required modifying and retraining a number of standard behaviors. The reported results were acquired through a long-term test ranging over a period of six months. This paper focuses on the characteristics of the users and their current ways of operation; how the robot was implemented and deployed. Additionally, this paper describes benefits and drawbacks from the users' perspective. A number of limitations in current robot technology are also identified. The findings show that the military relies on precise and thoroughly trained actions that can be executed with a minimum of ambiguity. To make use of robots, new behavioral schemes, which call for tactical optimization over several years, are needed. The most common application during the trials was reconnaissance inside buildings with uncertain enemy presence when time was not critical. Deploying the robot took more time than completing the task by traditional means, but in return kept the soldiers out of harm's way and enabled them to decrease weapon deployment. The range of the radio link, limited video feedback, and the bulky operator control unit were the features constraining the system's overall performance the most. On the other hand, did properties of the system, such as ruggedness, size, weight, terrain ability, and endurance, prove to match the application. The users were of the opinion that robots such as the Packbot Scout would be a valuable standard feature in urban intervention. © 2007 Wiley Periodicals, Inc. [source] MANAGEMENT OF NATURAL AND BIOTERRORISM INDUCED PANDEMICSBIOETHICS, Issue 7 2007MICHAEL G. TYSHENKO ABSTRACT A recent approach for bioterrorism risk management calls for stricter regulations over biotechnology as a way to control subversion of technology that may be used to create a man-made pandemic. This approach is largely unworkable given the increasing pervasiveness of molecular techniques and tools throughout society. Emerging technology has provided the tools to design much deadlier pathogens but concomitantly the ability to respond to emerging pandemics to reduce mortality has also improved significantly in recent decades. In its historical context determining just how ,risky' biological weapons is an important consideration for decision making and resource allocation. Management should attempt to increase capacity, share resources, provide accurate infectious disease reporting, deliver information transparency and improve communications to help mitigate the magnitude of future pandemics. [source] Technology Trends in Staffing and Assessment: A Practice NoteINTERNATIONAL JOURNAL OF SELECTION AND ASSESSMENT, Issue 2-3 2003John W. Jones This practice note listed and described, from a practitioner's perspective, ten dominant technology trends that are impacting the personnel testing industry. Five trends were classified as ,platform-centric,' and five were classified as ,information-centric.' Platform-centric trends were related to virtual career centers, integrated assessment platforms, media-rich assessments, technology-friendly tests, and the adaptation of personnel tests to emerging technologies. Information-centric trends were related to Internet-age access and fairness concerns, computer-enabled scoring innovations, strategic HR data warehousing and mining, satisfaction with computer-based assessments, and computer-based testing standards. A review of these ten technology trends suggests that the personnel testing industry is keeping pace with rapid technological innovations. [source] Thyroid tumor marker genomics and proteomics: Diagnostic and clinical implicationsJOURNAL OF CELLULAR PHYSIOLOGY, Issue 3 2010Angelo Carpi Two systems biology concepts, genomics and proteomics, are highlighted in this review. These techniques are implemented to optimize the use of thyroid tumor markers (TTM). Tissue microarray studies can produce genetic maps and proteomics, patterns of protein expression of TTM derived from preoperative biopsies and specimens. For instance, papillary and medullary thyroid cancers harbor RAS, RET, and BRAF genetic mutations. Follicular thyroid cancers harbor translocations and fusions of certain genes (PAX 8 and PPAR-gamma). Proteomic analysis from various tissue sources can provide useful information regarding the overall state of a thyroid cancer cell. Understanding the molecular events related to these genetic and protein alterations can potentially clarify thyroid cancer pathogenesis and guide appropriate molecular targeted therapies. However, despite the realization that these emerging technologies hold great promise, there are still significant obstacles to the routine use of TTM. These include equivocal thyroid nodule tissue morphologic interpretations, inadequate standardization of methods, and monetary costs. Interpretative shortcomings are frequently due to the relative scarcity of cellular material from fine-needle aspiration biopsy (FNAB) specimens. This can be rectified with large needle aspiration biopsy (LNAB) techniques and is exemplified by the favorable performance of galectin-3 determinations on LNAB specimens. J. Cell. Physiol. 224: 612,619, 2010. © 2010 Wiley-Liss, Inc. [source] DES Design: Theoretical Advantages and Disadvantages of Stent Strut Materials, Design, Thickness, and Surface CharacteristicsJOURNAL OF INTERVENTIONAL CARDIOLOGY, Issue 2009F.A.C.C., F.A.H.A., F.S.C.A.I., STEVEN R. BAILEY M.D. Endovascular stents have historically been manufactured using metals and metal composites. While metallic implants in nonvascular locations have been biologically well tolerated, endovascular implants have been plagued by neointimal proliferation resulting in recurrent stenosis. Using prior in vitro and in vivo outcomes, novel research projects are under way to improve vascular implants. This review summarizes prior investigations of metal stents, analyzes new biopolymeric systems, and examines emerging technologies and manufacturing processes for surface modifications as well as bioabsorbable stent materials. Limitations of these new materials and manufacturing processes will be discussed along with potential new biologic applications. [source] Technologies, Security, and Privacy in the Post-9/11 European Information SocietyJOURNAL OF LAW AND SOCIETY, Issue 2 2004Michael Levi Since 11 September 2001, many ,hard' and ,soft' security strategies have been introduced to enable more intensive surveillance and control of the movement of `suspect populations'. Suicide bombings have since generated a step-change in asymmetric threat analysis and public perceptions of risk. This article reviews how post-9/11 ,security' issues intersect with existing and emerging technologies, particularly those relating to identity, location, home, and work that will form the backbone of the European Information Society. The article explores the complexities generated by the way that these technologies work, sites of nationalist resistance, and formal bureaucratic roles. Many of the planned surveillance methods and technologies are convergence technologies aiming to bring together new and existing data sources, but are unable to do so because of poor data quality and the difficulty of using the integrated data to reduce serious crime risks. The delay may enable legal compliance models to be developed in order to protect the principles of privacy that are set out in the ECHR and the EC Data Protection Directive. Though (moral) panics produce changes in law, the article emphasizes the constraining effects of law. [source] Strategies for development of vaccines for control of ixodid tick speciesPARASITE IMMUNOLOGY, Issue 7 2006J. DE LA FUENTE SUMMARY Ticks are distributed worldwide and impact human and animal health, as well as food animal production. Control of ticks has been primarily by application of acaricides, which has resulted in selection of resistant ticks and environmental pollution. Vaccines have been shown to be a feasible tick control method that offers a cost-effective, environmentally friendly alternative to chemical control. However, identification of tick-protective antigens remains the limiting step in vaccine development. Tick antigens exposed naturally to the host during tick feeding and those concealed have both shown promise as candidate vaccine antigens. Development of vaccines against multiple tick species may be possible using highly conserved tick-protective antigens or by antigens showing immune cross-reaction to different tick species. Vaccines made from a combination of key protective antigens may greatly enhance vaccine efficacy. Preliminary studies have suggested the possibility of vaccine strategies directed toward both tick control and the blocking of pathogen transmission. Characterization of the tick genomes will have a great impact on the discovery of new protective antigens. The future of research directed toward tick vaccine development is exciting because of new and emerging technologies for gene discovery, and vaccine formulation and delivery. [source] Three-dimensional surface acquisition systems for the study of facial morphology and their application to maxillofacial surgeryTHE INTERNATIONAL JOURNAL OF MEDICAL ROBOTICS AND COMPUTER ASSISTED SURGERY, Issue 2 2007Chung How Kau Abstract Background There has been a growing interest in three-dimensional (3D) surface imaging devices over the last few years. Methods This comprehensive review discusses the various emerging technologies in this field of 3D imaging and applies the use of technology to oral and maxillofacial imaging. Results The paper shows that there is increased awareness and application of technology to the field. Conclusion 3D surface acquisition technology is improving at a rapid pace and has a place in oral and maxillofacial surgery. Copyright © 2007 John Wiley & Sons, Ltd. [source] Evaluating Oversight Systems for Emerging Technologies: A Case Study of Genetically Engineered OrganismsTHE JOURNAL OF LAW, MEDICINE & ETHICS, Issue 4 2009Jennifer Kuzma The U.S. oversight system for genetically engineered organisms (GEOs) was evaluated to develop hypotheses and derive lessons for oversight of other emerging technologies, such as nanotechnology. Evaluation was based upon quantitative expert elicitation, semi-standardized interviews, and historical literature analysis. Through an interdisciplinary policy analysis approach, blending legal, ethical, risk analysis, and policy sciences viewpoints, criteria were used to identify strengths and weaknesses of GEOs oversight and explore correlations among its attributes and outcomes. From the three sources of data, hypotheses and broader conclusions for oversight were developed. Our analysis suggests several lessons for oversight of emerging technologies: the importance of reducing complexity and uncertainty in oversight for minimizing financial burdens on small product developers; consolidating multi-agency jurisdictions to avoid gaps and redundancies in safety reviews; consumer benefits for advancing acceptance of GEO products; rigorous and independent pre- and post-market assessment for environmental safety; early public input and transparency for ensuring public confidence; and the positive role of public input in system development, informed consent, capacity, compliance, incentives, and data requirements and stringency in promoting health and environmental safety outcomes, as well as the equitable distribution of health impacts. Our integrated approach is instructive for more comprehensive analyses of oversight systems, developing hypotheses for how features of oversight systems affect outcomes, and formulating policy options for oversight of future technological products, especially nanotechnology products. [source] Developing the Media Zoo in Second LifeBRITISH JOURNAL OF EDUCATIONAL TECHNOLOGY, Issue 3 2009Matthew Wheeler Second Life (SL), an immersive virtual environment, is increasingly being adopted in education for both formal and informal teaching and learning uses. This paper addresses the process of developing a demonstrator presence in SL, the potential of the system for formal teaching and some practical ideas on how to successfully integrate such emerging technologies into practice. [source] Professional and economic factors affecting access to mammography: A crisis today, or tomorrow?,CANCER, Issue 3 2005Results from a national survey Abstract BACKGROUND Objective data and anecdotal reports have suggested that access to mammography may be declining because of facility closures and difficulty in recruiting and retaining radiologists and radiologic technologists. To gain insight into the practice patterns, use of emerging technologies, and concerns of breast imagers in current practice, the Society of Breast Imaging (SBI) conducted a national survey of breast imaging practices in the U.S. METHODS Between October 2003 and April 2004, the SBI conducted a survey of the SBI membership database, and received completed surveys from 575 breast imaging practices in the U.S. Responses to the survey regarding practice characteristics, the utilization of standard and emerging technologies, staffing, malpractice, finance, and morale were analyzed. RESULTS Job vacancies for radiologists who read mammograms were reported in 163 practices (29%), 59 of which (10%) had 2 or more openings. A higher proportion of practices with job openings had long appointment waiting times for asymptomatic women when compared with fully staffed practices. Unfilled fellowship positions also were common, with 41 of 65 practices that offer fellowships reporting 47 openings. Among 554 responding practices, 55% reported that someone in their practice was sued because of a mammography related case within the past 5 years, and 50% of practices reported that the threat of lawsuits made radiologist staffing "moderately" or "a lot" more difficult. Of 521 responding practices, 35% reported financial losses in 2002. One in 5 respondents reported that they would prefer to spend less time in mammography, and fewer than 1 in 3 would recommend a breast imaging fellowship to a relative or friend. Emerging technologies, such as breast magnetic resonance imaging and screening ultrasound, currently are being performed in many practices. CONCLUSIONS The survey results provide support for anecdotal reports that breast imaging practices face significant challenges and stresses, including shortages of key personnel, a lack of trainees, malpractice concerns, financial constraints, increased workload due to emerging technologies, low appeal of breast imaging as a career specialty, and the steady rise in the population of women of screening age. Cancer 2005. © 2005 American Cancer Society. [source] METHODS FOR STUDYING THE PHYSIOLOGY OF KIDNEY OXYGENATIONCLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, Issue 12 2008Roger G Evans SUMMARY 1An improved understanding of the regulation of kidney oxygenation has the potential to advance preventative, diagnostic and therapeutic strategies for kidney disease. Here, we review the strengths and limitations of available and emerging methods for studying kidney oxygen status. 2To fully characterize kidney oxygen handling, we must quantify multiple parameters, including renal oxygen delivery (DO2) and consumption (VO2), as well as oxygen tension (Po2). Ideally, these parameters should be quantified both at the whole-organ level and within specific vascular, tubular and interstitial compartments. 3Much of our current knowledge of kidney oxygen physiology comes from established techniques that allow measurement of global kidney DO2 and VO2, or local tissue Po2. When used in tandem, these techniques can help us understand oxygen mass balance in the kidney. Po2 can be resolved to specific tissue compartments in the superficial cortex, but not deep below the kidney surface. We have limited ability to measure local kidney tissue DO2 and VO2. 4Mathematical modelling has the potential to provide new insights into the physiology of kidney oxygenation, but is limited by the quality of the information such models are based on. 5Various imaging techniques and other emerging technologies have the potential to allow Po2 mapping throughout the kidney and/or spatial resolution of Po2 in specific renal tissues, even in humans. All currently available methods have serious limitations, but with further refinement should provide a pathway through which data obtained from experimental animal models can be related to humans in the clinical setting. [source] Recent Advances in the Recovery and Improvement of Functional Proteins from Fish Processing By-Products: Use of Protein Glycation as an Alternative MethodCOMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY, Issue 4 2009Esther Sanmartín ABSTRACT:, The recovery of proteins from fish by-products for their utilization as food ingredients is becoming of increasing interest in the food industry as they may possess good functional and nutritional properties. This article reviews the main processing methods, such as enzymatic hydrolysis, pH shifting, membrane filtration, and some emerging technologies, used for the recovery of proteins from fish processing by-products. The impact of these methods on the yield and, especially, on the functionality of the recovered proteins is discussed in detail. Considering that there is a huge amount of fish by-products destined for nonfood use, one of the current challenges of the food industry is the development of technologies that allow the recovery of ingredients from the fish processing by-products with potential to provide new and natural sources of high-value functional ingredients for human consumption. In this sense, this review explores the potential use of the glycation reaction to increase the yield of proteins extracted from fish by-products, as well as the effect of this reaction on their functional and biological properties. [source] Security Maintenance Mediation: a technology for preventing unintended security breachesCONCURRENCY AND COMPUTATION: PRACTICE & EXPERIENCE, Issue 1 2004Roger (Buzz) KingArticle first published online: 4 DEC 200 Abstract Web-resident information is becoming ,smarter', in the sense that emerging technology will support the annotation of it with ontological terms, which will be used to locate and reuse information. This will pose a great security risk in the form of unintended breaches (as distinct from deliberate invasions). Web-resident information will be far more readily available and relevant, thus causing inadvertent releases of secure information to potentially cause it to be diffusely spread across the Internet. Then as this information is iteratively transformed and integrated with other information, it will become irretrievable and potentially used in a myriad of unpredictable ways. The problem is that ontological annotations, while making information more understandable in its original form, do not provide a means for easily capturing the complex semantics of information that has been transformed via abstraction, aggregation, and integration. This demands the development of a semantically rich way of specifying ,views' of Web information, to which security controls can be attached. Also needed is a way for users of secure information to easily and voluntarily blend,and thereby propagate,security controls as information is transformed. Information mediators designed by collaborative teams of experts are proposed as the vehicle for wrapping information, so that at each step of reuse, high-level views and their corresponding integrity controls can be made easily accessible to trusted users who will then be able to ensure their proper maintenance. Copyright © 2004 John Wiley & Sons, Ltd. [source] Use of Dynamic Telepathology in Mohs Surgery: A Feasibility StudyDERMATOLOGIC SURGERY, Issue 5 2002Kishwer S. Nehal MD background. Telepathology is an emerging technology for remote pathology consultation and diagnosis. objective. To assess the diagnostic accuracy and utility of a dynamic telepathology system in the setting of Mohs surgery. methods. Using a dynamic telepathology system, a single dermatopathologist at a remote site assessed the following cases: (1) 50 fixed-tissue slides of basal and squamous cell carcinomas for pathologic diagnosis; (2) 40 frozen-section slides from Mohs surgery for the presence or absence of tumor; (3) 20 frozen-section slides from Mohs surgery for intraoperative consultation with the Mohs surgeon. All 110 slides were then randomly reviewed by the same dermatopathologist by conventional light microscopy. Telepathology and conventional light microscopy diagnoses were then compared. results. There was complete agreement between telepathology and conventional light microscopy diagnoses. conclusion. Dynamic telepathology is a convenient, useful, and accurate system for remote diagnosis and consultation in the setting of Mohs surgery. [source] Glucose sensors: a review of current and emerging technologyDIABETIC MEDICINE, Issue 3 2009N. S. Oliver Abstract Glucose monitoring technology has been used in the management of diabetes for three decades. Traditional devices use enzymatic methods to measure glucose concentration and provide point sample information. More recently continuous glucose monitoring devices have become available providing more detailed data on glucose excursions. In future applications the continuous glucose sensor may become a critical component of the closed loop insulin delivery system and, as such, must be selective, rapid, predictable and acceptable for continuous patient use. Many potential sensing modalities are being pursued including optical and transdermal techniques. This review aims to summarize existing technology, the methods for assessing glucose sensing devices and provide an overview of emergent sensing modalities. [source] Digital Imaging: A Promising Tool for Mushroom IdentificationACADEMIC EMERGENCY MEDICINE, Issue 7 2003Connie B. Fischbein BA Mushroom poisoning is a diagnostic and treatment dilemma for health care professionals. Decisions regarding treatment following ingestions are usually made without a firm identification of the fungus and tend to be more aggressive than necessary. The identification of mushrooms is beyond the scope of health care professionals, and a mycologist is essential to make an accurate identification. Telemedicine and digital imaging is an emerging technology that can assist in mushroom identification and facilitate patient care. The efficacy of using digital images sent over the Internet was tested in a pilot project. This article describes three cases in which digital images and verbal descriptions assisted in mushroom identification. When the actual specimen was sent to a mycologist, a definitive identification was obtained and compared with the presumptive identification. Digital images alone do not permit definitive identification; however, they often contain sufficient information to help the clinician rule out the possibility of a severely toxic species. Data accumulated to date indicate that digital imaging can be an important tool in the diagnosis and treatment of mushroom ingestion, and possibly other biologicals such as plants, insects, and reptiles. [source] Endovascular stent implantation for treatment of peripheral artery diseaseEUROPEAN JOURNAL OF CLINICAL INVESTIGATION, Issue 3 2007M. Schillinger Endovascular stent implantation is a rapidly emerging technology for treatment of arterial obstructions in the entire circulation. During recent years, several randomized studies evaluated the effects of stenting in lower limb arteries. We herein provide an overview on data of trials in the iliac and femoropopliteal vessel area discussing the benefits and limitations of endovascular stents. In the iliac arteries, midterm and long-term data from one randomized trial including analysis on patency, clinical outcomes, cost-effectiveness and quality of life indicate that balloon angioplasty with selective stenting remains the therapy of choice for endovascular revascularization. In the femoropopliteal arteries, balloon-expanding stents were not superior to balloon angioplasty for treatment of short lesions, and self-expanding nitinol stents also failed to show a beneficial effect in short lesions below 5 cm. However, including longer lesions, one randomized trial indicated a beneficial effect of nitinol stents in lesions with a median length around 10,12 cm. Further studies and longer follow-up intervals are needed to confirm these data. Meanwhile, balloon angioplasty with optional stenting also remains the recommended endovascular approach for the femoropopliteal segment. [source] Controllable Shifts in Threshold Voltage of Top-Gate Polymer Field-Effect Transistors for Applications in Organic Nano Floating Gate MemoryADVANCED FUNCTIONAL MATERIALS, Issue 2 2010Kang-Jun Baeg Abstract Organic field-effect transistor (FET) memory is an emerging technology with the potential to realize light-weight, low-cost, flexible charge storage media. Here, solution-processed poly[9,9-dioctylfluorenyl-2,7-diyl]-co-(bithiophene)] (F8T2) nano floating gate memory (NFGM) with a top-gate/bottom-contact device configuration is reported. A reversible shift in the threshold voltage (VTh) and reliable memory characteristics was achieved by the incorporation of thin Au nanoparticles (NPs) as charge storage sites for negative charges (electrons) at the interface between polystyrene and cross-linked poly(4-vinylphenol). The F8T2 NFGM showed relatively high field-effect mobility (µFET) (0.02,cm2 V,1 s,1) for an amorphous semiconducting polymer with a large memory window (ca. 30,V), a high on/off ratio (more than 104) during writing and erasing with an operation voltage of 80,V of gate bias in a relatively short timescale (less than 1,s), and a retention time of a few hours. This top-gated polymer NFGM could be used as an organic transistor memory element for organic flash memory. [source] Nanotechnologies: Tools for sustainability in a new wave of water treatment processesINTEGRATED ENVIRONMENTAL ASSESSMENT AND MANAGEMENT, Issue 4 2006Jean-Yves Bottero Abstract In the environmental technology industry alone, nanomaterials will enable new means of reducing the production of industrial wastes, using resources more sparingly, remediating industrial contamination, providing potable water, and improving the efficiency of energy production. This paper discusses three new kinds of nanotechnology materials that should be developed in the future: Membranes, oxidants, and adsorbents. Nanoscale control of membrane architecture may yield membranes of greater selectivity and lower cost in both water treatment and water fabrication. Fullerene-based oxidant nanomaterials such as C60 have a high electron affinity and reactivity, and are capable of producing reactive oxygen species such as singlet oxygen and superoxides. Fullerenes might be used in engineered systems to photocatalytically oxidize organic contaminants, or inhibit or inactivate microbes. The ability to tailor surfaces can help to increase adsorbing capacities or recognize specific contaminants. The potential environmental risks are that nanomaterials could interact with biota and that their toxicity adversely may affect ecosystems. As nanochemistry emerges as an important force behind new environmental technologies, we are also presented with the responsibility of considering the environmental implications of an emerging technology at its inception and taking every precaution to ensure that these technologies develop as tools of sustainability rather than becoming future liabilities. [source] Status and development of PEM fuel cell technologyINTERNATIONAL JOURNAL OF ENERGY RESEARCH, Issue 5 2008F. Barbir Abstract Fuel cells are an emerging technology with applications in transportation, stationary and portable power generation, with outputs ranging from mW to MW. The most promising and most widely researched, developed and demonstrated type of fuel cells is proton exchange membrane (PEM) fuel cell. State of the art in PEM fuel cell technology and challenges in their development and widespread applications are discussed. Copyright © 2007 John Wiley & Sons, Ltd. [source] On the business value and technical challenges of adopting Web servicesJOURNAL OF SOFTWARE MAINTENANCE AND EVOLUTION: RESEARCH AND PRACTICE, Issue 1-2 2004S. Tilley Abstract This paper provides a balanced perspective of the business value and technical challenges of adopting Web services. Technology adoption is a continual challenge for both tool developers and enterprise users. Web services are a prime example of an emerging technology that is fraught with adoption issues. Part of the problem is separating marketing hype from business reality. Web services are network-accessible interfaces to application functionality. They are built using Internet technologies such as XML and standard protocols such as SOAP. The adoption issues related to Web services are complex and multifaceted. For example, determining whether this technology is a fundamental advance, rather than something old under a new name, requires technical depth, business acumen, and considerable historical knowledge of past developments. A sample problem from the health care industry is used to illustrate some of the adoption issues. Copyright © 2004 John Wiley & Sons, Ltd. [source] A model for quantitative evaluation of an end-to-end question-answering systemJOURNAL OF THE AMERICAN SOCIETY FOR INFORMATION SCIENCE AND TECHNOLOGY, Issue 8 2007Nina Wacholder We describe a procedure for quantitative evaluation of interactive question-answering systems and illustrate it with application to the High-Quality Interactive Question-Answering (HITIQA) system. Our objectives were (a) to design a method to realistically and reliably assess interactive question-answering systems by comparing the quality of reports produced using different systems, (b) to conduct a pilot test of this method, and (c) to perform a formative evaluation of the HITIQA system. Far more important than the specific information gathered from this pilot evaluation is the development of (a) a protocol for evaluating an emerging technology, (b) reusable assessment instruments, and (c) the knowledge gained in conducting the evaluation. We conclude that this method, which uses a surprisingly small number of subjects and does not rely on predetermined relevance judgments, measures the impact of system change on work produced by users. Therefore this method can be used to compare the product of interactive systems that use different underlying technologies. [source] Governing nursing conduct: the rise of evidence-based practiceNURSING INQUIRY, Issue 3 2002Sarah Winch Governing nursing conduct: the rise of evidence-based practice Drawing on the Foucauldian concept of ,governmentality' to analyse the evidence-based movement in nursing, we argue that it is possible to identify the governance of nursing practice and hence nurses across two distinct axes; that of the political (governance through political and economic means) and the personal (governance of the self through the cultivation of the practices required by nurses to put evidence into practice). The evaluation of nursing work through evidence-based reviews provides detailed information that may enable governments to target and instruct nurses regarding their work in the interest of preserving the health of the population as a whole. Political governance of the nursing population becomes possible through centralised discursive mechanisms, such as evidence-based reviews that present nursing practice as an intelligible field whose elements are connected in a more or less systematic manner. The identity of the evidence-based nurse requires the modern nurse to develop new skills and attitudes. Evidence-based nursing is an emerging technology of government that judges nursing research and knowledge and has the capacity to direct nursing practice at both the political and personal level. [source] The Use of Natural Systems to Remediate Groundwater: Department of Energy Experience at the Savannah River SiteREMEDIATION, Issue 3 2002Gerald C. Blount Natural remediation is moving toward the forefront as engineers clean groundwater at the Savannah River Site (SRS), a major Department of Energy (DOE) installation near Aiken, South Carolina. This article reviews two successful, innovative remediation methods currently being deployed: biosparging to treat chlorinated solvents and phytoremediation to address tritium in groundwater. The biosparging system reintroduces oxygen into the groundwater and injects nutrient compounds for in-situ remediation. The system has greatly reduced the concentrations of trichloroethylene (TCE) and vinyl chloride in wells downgradient from a sanitary landfill (SLF). Phytoremediation is an emerging technology that promises effective and inexpensive cleanup of certain hazardous wastes. Using natural processes, plants can break down, trap and hold, or transpire contaminants. This article discusses the use of phytoremediation to reduce the discharge of tritium to an on-site stream at SRS. © 2002 Wiley Periodicals Inc.* [source] | ||||||||||||||||||||||||||||||||||||||||