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Emerging Class (emerging + class)
Selected AbstractsA Design Theory Approach to Building Strategic Network-Based Customer Service Systems,DECISION SCIENCES, Issue 3 2009M. Kathryn Brohman ABSTRACT Customer service is a key component of a firm's value proposition and a fundamental driver of differentiation and competitive advantage in nearly every industry. Moreover, the relentless coevolution of service opportunities with novel and more powerful information technologies has made this area exciting for academic researchers who can contribute to shaping the design and management of future customer service systems. We engage in interdisciplinary research,across information systems, marketing, and computer science,in order to contribute to the service design and service management literature. Grounded in the design-science perspective, our study leverages marketing theory on the service-dominant logic and recent findings pertaining to the evolution of customer service systems. Our theorizing culminates with the articulation of four design principles. These design principles underlie the emerging class of customer service systems that, we believe, will enable firms to better compete in an environment characterized by an increase in customer centricity and in customers' ability to self-serve and dynamically assemble the components of solutions that fit their needs. In this environment, customers retain control over their transactional data, as well as the timing and mode of their interactions with firms, as they increasingly gravitate toward integrated complete customer solutions rather than single products or services. Guided by these design principles, we iterated through, and evaluated, two instantiations of the class of systems we propose, before outlining implications and directions for further cross-disciplinary scholarly research. [source] Fibroblast cell attachment and growth on nanoengineered sculptured thin filmsJOURNAL OF BIOMEDICAL MATERIALS RESEARCH, Issue 1 2007M. C. Demirel Abstract Nanoengineered parylene-C sculptured thin films (STFs) are deposited on glass and silicon substrates using a direct one-step growth technique. The deposited STFs support fibroblast cell attachment and proliferation in vitro, which is an early indication of biocompatibility and bioactivity of this emerging class of biomaterials. Surface modification of endoprostheses of the small joints of the hand, which heal with fibrous stabilization, may be greatly enhanced by such nanoengineered biomaterials. © 2006 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2006 [source] Interactions of the "piano-stool" [ruthenium(II) (,6 -arene)(en)CL]+ complexes with water and nucleobases; ab initio and DFT studyJOURNAL OF COMPUTATIONAL CHEMISTRY, Issue 12 2009k Futera Abstract Piano stool ruthenium complexes of the composition [Ru(II)(,6 -arene)(en)Cl]+/2+ (en = ethylenediamine) represent an emerging class of cisplatin-analogue anticancer drug candidates. In this study, we use computational quantum chemistry to characterize the structure, stability and reactivity of these compounds. All these structures were optimized at DFT(B3LYP)/6-31G(d) level and their single point properties were determined by the MP2/6-31++G(2df,2pd) method. Thermodynamic parameters and rate constants were determined for the aquation process, as a replacement of the initial chloro ligand by water and subsequent exchange reaction of aqua ligand by nucleobases. The computations were carried out at several levels of DFT and ab initio theories (B3LYP, MP2 and CCSD) utilizing a range of bases sets (from 6-31G(d) to aug-cc-pVQZ). Excellent agreement with experimental results for aquation process was obtained at the CCSD level and reasonable match was achieved also with the B3LYP/6-31++G(2df,2pd) method. This level was used also for nucleobase-water exchange reaction where a smaller rate constant for guanine exchange was found in comparison with adenine. Although adenine follows a simple replacement mechanism, guanine complex passes by a two-step mechanism. At first, Ru-O6(G) adduct is formed, which is transformed through a chelate TS2 to the Ru-N7(G) final complex. In case of guanine, the exchange reaction is more favorable thermodynamically (releasing in total by about 8 kcal/mol) but according to our results, the rate constant for guanine substitution is slightly smaller than the analogous constant in adenine case when reaction course from local minimum is considered. © 2008 Wiley Periodicals, Inc. J Comput Chem, 2009 [source] The Chemical Interaction of Silver,Palladium Alloy Electrodes with Bismuth-Based PiezomaterialsJOURNAL OF THE AMERICAN CERAMIC SOCIETY, Issue 4 2010Denis Schuetz Multilayer technology relies heavily on the chemical compatibility of metal and ceramic. This work focuses on the ceramic,electrode interaction between 92Bi0.5Na0.5TiO3,6 BaTiO3,2K0.5Na0.5NbO3 [(Bi0.46Na0.47Ba0.06K0.01)(Nb0.02Ti0.98)O3], a promising actuator material and forerunner to an emerging class of lead-free actuator materials, and a silver,palladium alloy for inner electrodes, the only currently viable material for the firing temperatures necessary (1100°C). Of special concern was the high content of bismuth in the ceramic since prior investigations suggest that Bi2O3 (as well as various bismuth titanates) used as a fluxor in electroceramics are prone to forming the intermediate-phase bismuth palladate (Bi2PdO4), which can lead to poor contacting and delamination of multilayer stacks. Remarkably, no evidence of bismuth palladate formation could be found. However, the phase relations of the bulk ceramic have proven to be quite complex. Potassium was being drained out of the bulk ceramic either constituting the secondary phase K4Na2(TiO3)3 in unmodified experiments or evaporating and being replaced by silver in samples in contact with Ag. Mechanisms for the formation of these phases or the lack thereof are proposed. These findings were obtained by XRD, TG-DSC, and SEM with EDX, and LA-ICPMS. [source] Between love and property: Voice, sentiment, and subjectivity in the reform of daughter's inheritance in NepalAMERICAN ETHNOLOGIST, Issue 3 2009LAURA KUNREUTHER ABSTRACT In this article, I trace the relation between the figure of voice and subjectivity by examining a Nepali reform movement that sought to give daughters a birth right to ancestral property. At its heart was a contest over emerging class and gender subjectivities that were repeatedly defined through the figure of the voice and related practices of address, hailing, and recognition. The competing formations of voice I discuss here entail shifting notions of intimacy. To challenge property relations thus meant to change existing practices of speech, sentiment, and the meaning of voice itself. [voice, sentiment, property, subjectivity, Nepal, gender, class distinction] [source] Therapeutic potential of RNA interference against cancerCANCER SCIENCE, Issue 8 2006Fumitaka Takeshita One of the most dramatic events of the past 5 years in the field of molecular biology has been the discovery of RNA interference (RNAi). Although RNAi is an evolutionarily conserved phenomenon for sequence-specific gene silencing in mammalian cells, exogenous small interfering RNA (siRNA) and vector-based short hairpin RNA (shRNA) can also invoke RNAi responses. Both are now not only experimental tools for analyzing gene function but are expected to be excellent avenues for drug target discovery and the emerging class of gene medicine for targeting incurable diseases such as cancer. The success of cancer therapeutic use of RNAi relies on the development of safe and efficacious delivery systems that introduce siRNA and shRNA expression vectors into target tumor cells. For their delivery, a variety of strategies have been used, most of them based on traditional gene therapy delivery systems. In this review, we present siRNA delivery method strategies and discuss the potential of RNAi-based gene therapy in cancer treatment. (Cancer Sci 2006; 97: 689,696) [source] | ||||||||||