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Electrophilic Fluorination (electrophilic + fluorination)

Distribution by Scientific Domains
Chemistry100%

Selected Abstracts

Convenient Electrophilic Fluorination of Functionalized Aryl and Heteroaryl Magnesium Reagents,

ANGEWANDTE CHEMIE, Issue 12 2010
Shigeyuki Yamada Dr.
Ganz einfach: Die elektrophile Fluorierung einer Vielzahl aromatischer und heteroaromatischer Grignard-Reagentien gelingt glatt mit (PhSO2)2NF als Fluorierungsmittel in einer 4:1-Mischung aus CH2Cl2 und Perfluordecalin (siehe Schema). In diesem Lösungsmittelsystem sind die meisten Nebenreaktionen zurückgedrängt. [source]

ChemInform Abstract: Convenient Electrophilic Fluorination of Functionalized Aryl and Heteroaryl Magnesium Reagents.

CHEMINFORM, Issue 29 2010
Shigeyuki Yamada
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

ChemInform Abstract: Facile Synthesis of Monofluoro ,-Lactones and Pyrrolidine Derivatives via Electrophilic Fluorination of Allenoic Acids and Amides.

CHEMINFORM, Issue 20 2009
Haifeng Cui
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

Copper(II) Triflate-bis(oxazoline)-Catalyzed Enantioselective Electrophilic Fluorination of ,-Ketoesters.

CHEMINFORM, Issue 28 2004
Jun-An Ma
No abstract is available for this article. [source]

Ionic Liquids as Solvents of Choice for Electrophilic Fluorination: Fluorination of Indoles by F-TEDA-BF4.

CHEMINFORM, Issue 48 2002
Jerome Baudoux
Abstract For Abstract see ChemInform Abstract in Full Text. [source]

ChemInform Abstract: Electrophilic Fluorination Mediated by Cinchona Alkaloids: Highly Enantioselective Synthesis of ,-Fluoro-,-phenylglycine Derivatives.

CHEMINFORM, Issue 14 2002
Barbara Mohar
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

ChemInform Abstract: Diastereoselective Electrophilic Fluorination of Enantiopure ,-Silylketones Using N-Fluoro-benzosulfonimide: Regio- and Enantioselective Synthesis of ,-Fluoroketones.

CHEMINFORM, Issue 10 2002
Dieter Enders
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

ChemInform Abstract: The First Application of Selectfluor in Electrophilic Fluorination of Amines: A New Route to -NF2, -NHF, and >NF Compounds.

CHEMINFORM, Issue 40 2001
Rajendra P. Singh
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

Trifluoromethanesulfonic acid, an alternative solvent medium for the direct electrophilic fluorination of DOPA: new syntheses of 6-[18F]fluoro- L -DOPA and 6-[18F]fluoro- D -DOPA

JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS, Issue 14 2007
Babak Behnam Azad
Abstract Previous work from this laboratory has shown that the direct fluorination of 3, 4-dihydroxy-phenyl- L -alanine (L -DOPA) in anhydrous HF (aHF) or BF3/HF with F2 is an efficient method for the synthesis of 6-fluoro- L -DOPA. Since then, 18F-labeled 6-fluoro- L -DOPA ([18F]6-fluoro- L -DOPA) has been used to study presynaptic dopaminergic function in the human brain and to monitor gastrointestinal carcinoid tumors. This work demonstrates that the reactivity and selectivity of F2 toward L -DOPA in CF3SO3H is comparable with that in aHF. This new synthetic procedure has led to the production of [18F]fluoro- L -DOPA and [18F]fluoro-D-DOPA isomers in 17±2% radiochemical yields (decay corrected with respect to [18F]F2). The 2- and 6-FDOPA isomers were separated by HPLC and subsequently characterized by 19F NMR spectroscopy. The corresponding [18F]-FDOPA enantiomers have been obtained in clinically useful quantities by a synthetic approach that avoids the use of aHF. Copyright © 2007 John Wiley & Sons, Ltd. [source]