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Efficient Cross-Coupling (efficient + cross-coupl)

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Chemistry100%

Selected Abstracts

Extremely Efficient Cross-Coupling of Benzylic Halides with Aryltitanium Tris(isopropoxide) Catalyzed by Low Loadings of a Simple Palladium(II) Acetate/Tris(p -tolyl)phosphine System

ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 10 2010
Chi-Ren Chen
Abstract Highly efficient coupling reactions of benzylic bromides or chlorides with aryltitanium tris(isopropoxide) [ArTi(O- i- Pr)3] catalyzed by a simple palladium(II) acetate/tris(p -tolyl)phosphine [Pd(OAc)2/ P(p -tolyl)3] system are reported. The coupling reactions proceed in general at room temperature employing low catalyst loadings of 0.02 to 0.2,mol%, affording coupling products in excellent yields of up to 99%. For benzylic bromides bearing strong electron-withdrawing cyano (CN) or trifluoromethyl (CF3) substituents, the reactions require a higher catalyst loading of 1,mol%, or the reactions are carried out at 60,°C. The catalytic system also tolerates (1-bromoethyl)benzene bearing ,-hydrogen atoms while using a catalyst loading of 1,mol% to afford the coupling product in a 70% yield. [source]

Nickel(0)/Imidazolium Carbene Catalyst System for Efficient Cross-Coupling of Aryl Bromides and Chlorides with Organomanganese Reagents

ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 9 2006
Anne Leleu
Abstract N,N, -Bis(2,6-diisopropylphenyl)imidazolium chloride associated with nickel(II) acetylacetonate (3,5 mol,%) was used as catalyst to efficiently cross-couple functionalized aryl bromides with organomanganese reagents. The reactions were performed between 0,°C and room temperature, giving unsymmetrical biaryls in 0.25 to 24,h with 52 to 100,% yields for isolated materials. Aryl chlorides showed slightly diminished reactivity in Ni/2 IPr-catalyzed cross-couplings and good yields could only be attained with activated or neutral substrates. [source]

ChemInform Abstract: A Novel and Efficient Cross-Coupling of Tris(fluorinated phenyl)boroxins with Disulfides Catalyzed by CuI/1,10-Phenanthroline.

CHEMINFORM, Issue 42 2010
Chuanming Yu
Abstract Boroxin (I) or its tris(3-fluorophenyl) analogue give by coupling with aromatic or aliphatic disulfides the corresponding sulfides. [source]

Efficient Cross-Coupling of Functionalized Arylzinc Halides Catalyzed by a Nickel Chloride,Diethyl Phosphite System.

CHEMINFORM, Issue 10 2006
Andrei Gavryushin
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]