Home About us Contact
|
Home About us Contact | ||
|
|
||
Efficient Asymmetric Synthesis (efficient + asymmetric_synthesis)
Selected AbstractsAn Efficient Asymmetric Synthesis of 2-Substituted 1,4-Benzodiazepin-3-one as a Potential Molecular ScaffoldEUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 8 2005Nuria Cabedo Abstract 2-Substituted 1,4-benzodiazepine-2-one compounds (9,12) were obtained by a highly diastereoselective alkylation of a seven-membered ring benzolactam (8) in the presence of (R)-phenylglycinol as a chiral inductor. The corresponding acid derivative (16) afforded a conformationally constrained structure suitable for preparing peptidomimetic analogues useful as a novel molecular scaffold. After cleavage of the chiral appendage this approach might also lead efficiently to enantiomerically pure 2-substituted benzodiazepines (15). (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005) [source] ChemInform Abstract: An Efficient Asymmetric Synthesis of the Potent ,-Blocker ICI-118,551 Allows the Determination of Enantiomer Dependency on Biological Activity.CHEMINFORM, Issue 43 2010James R. Baker Abstract A highly efficient asymmetric synthesis of the title compound is developed. [source] An Efficient Asymmetric Synthesis of Cascarillic Acid (I).CHEMINFORM, Issue 37 2006Matt Cheeseman Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Efficient Asymmetric Synthesis of the Vasopeptidase Inhibitor BMS-189921.CHEMINFORM, Issue 51 2003Janak Singh No abstract is available for this article. [source] Nonproteinogenic Amino Acids: An Efficient Asymmetric Synthesis of (S)-(-)-Acromelobic Acid (I) and (S)-(-)-Acromelobinic Acid (II).CHEMINFORM, Issue 52 2002Maciej Adamczyk No abstract is available for this article. [source] ChemInform Abstract: Efficient Asymmetric Synthesis of (S)-2-Ethylphenylpropanoic Acid Derivative, a Selective Agonist for Human Peroxisome Proliferator-Activated Receptor Alpha.CHEMINFORM, Issue 49 2002Masahiro Nomura Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Efficient Asymmetric Synthesis of ,-Trifluoromethyl-Substituted Primary Amines via Nucleophilic 1,2-Addition to Trifluoroacetaldehyde SAMP, or RAMP,Hydrazone.CHEMINFORM, Issue 35 2001Dieter Enders Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] A novel asymmetric synthesis of tritium and carbon-14 labeled (R)-ibuprofenJOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS, Issue 3 2006Yinsheng Zhang Abstract An efficient asymmetric synthesis of tritium and carbon-14 labeled R -ibuprofen was achieved in good overall yield (15% and 47%, respectively) and excellent enantiomerical excess (>98% e.e.), using (4R, 5S)-4-methyl-5-phenyl-2-oxazolidinone as a chiral auxiliary. Copyright © 2006 John Wiley & Sons, Ltd. [source] ChemInform Abstract: An Efficient Asymmetric Synthesis of the Potent ,-Blocker ICI-118,551 Allows the Determination of Enantiomer Dependency on Biological Activity.CHEMINFORM, Issue 43 2010James R. Baker Abstract A highly efficient asymmetric synthesis of the title compound is developed. [source] | ||||||||||