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Selected Abstracts9. Erlanger Dermatologen-Nachmittag (EDN) am 24.JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, Issue 1 2002First page of article [source] Oxidative stress in the pathogenesis of experimental diabetic neuropathyJOURNAL OF NEUROCHEMISTRY, Issue 2003P. A. Low We evaluated the effects of chronic hyperglycemia on L5 DRG neurons. Experimental diabetic neuropathy (EDN) was induced by streptozotocin. We studied peripheral nerve after 1, 3, 12 months of diabetes. A conduction deficit was present from the first month and persisted over 12 months, affecting mainly sensory fibers. 8-Hydroxy-deoxyguanosine labeling was significantly increased at all time points in DRG neurons, indicating oxidative injury. Caspase-3 labeling was increased at all three time-points, indicating commitment to the efferent limb of the apoptotic pathway. Apoptosis was confirmed by a significant increase in the percent of neurons undergoing apoptosis (TUNEL staining) at 1 month (8%), 3 months (7%) and 12 months (11%). Morphometry of DRG showed a selective loss (42%) of the largest neurons. These findings support the concept that oxidative stress leads to oxidative injury of DRG neurons, with mitochondrium as a specific target, leading to apoptosis and a predominantly sensory neuropathy. [source] Effects of Polymer Architecture and Composition on the Adhesion of Poly(tetrafluoroethylene)CHEMPHYSCHEM, Issue 6 2006Chen-Yuan Tu Dr. Abstract Poly(glycidyl methacrylate), PGMA, chains in linear and arborescent structures were incorporated onto surfaces of poly(tetrafluoroethylene), PTFE, films by hydrogen plasma and ozone treatment and atom transfer radical polymerization. The epoxide groups of the PGMA chains were further reacted with acetic acid (AAc), oxalic acid (XAc), allyl amine (AA), and ethylenediamine (EDN) to introduce hydroxyl and amine groups to the surfaces of the PTFE films. Surface characterizations performed by Fourier Transform infrared attenuated total reflectance (FTIR-ATR) spectroscopy and X-ray photoelectron spectroscopy (XPS) confirmed the surface modification and the chemical structure. The PGMA chains in arborescent structures show a high effectiveness for the enhancement of the adhesion of PTFE films. The adhesion of PTFE films was also significantly enhanced by ring-opening reactions of the PGMA epoxide groups with acetic acid and amine compounds. A high value of 9.5 N,cm,1 in the optimum 180° peel strength test was observed with PTFE/copper assemblies. [source] Increased production of cysteinyl leukotrienes and prostaglandin D2 during human anaphylaxisCLINICAL & EXPERIMENTAL ALLERGY, Issue 1 2009E. Ono Abstract Background Anaphylaxis is a life-threatening syndrome resulting from the sudden release of mast cell- and basophil-derived mediators into the circulation. However, pathological evidence of the association between inflammatory mediators and human anaphylaxis is insufficient. Objective The aim of this study was to better understand the relationship between in vivo production of inflammatory mediators and the pathogenesis of anaphylaxis. We also sought to evaluate mast cell activation in anaphylaxis. Methods We measured the concentrations of various inflammatory mediators in urine samples, which were collected from 32 anaphylactic patients during the onset of anaphlaxis and during clinical remission, 21 patients with asthma on acute exacerbation and 15 healthy control subjects. Blood and urine specimens were collected from the patients after provocation test. Urinary leukotriene E4 (LTE4), 9,, 11,-prostaglandin F2 (9,, 11,-PGF2), eosinophil-derived neurotoxin (EDN) and leukotriene B4 glucuronide (LTBG) concentrations were determined by enzyme immunoassay, and the activity of plasma platelet-activating factor acetylhydrolase and serum tryptase concentration were measured using commercially available kits. Results Significantly higher concentrations of urinary LTE4 and 9,, 11,-PGF2, which immediately decreased during clinical remission, were observed in the anaphylactic patients than in asthmatic patients on acute exacerbation and healthy control subjects. Concentrations of EDN and LTBG were not significantly different among the anaphylactic patients, asthmatic patients on acute exacerbation and healthy subjects. There was a significant correlation between urinary LTE4 and 9,, 11,-PGF2 concentrations in the anaphylactic patients (r=0.672, P=0.005, n=32). In addition, LTE4 concentration in patients with anaphylactic shock is significantly elevated compared with that in patients without anaphylactic shock. Conclusions This is a report on the significant increase in urinary LTE4 and 9,, 11,-PGF2 concentrations during anaphylaxis. Urinary LTE4 and 9,, 11,-PGF2 concentrations may be a reliable marker of endogenous production of inflammatory mediators associated with anaphylaxis. [source] Vegetable Seed Production, 2nd EdnJOURNAL OF AGRONOMY AND CROP SCIENCE, Issue 2 2001Article first published online: 21 DEC 200 [source] Sabiston Textbook of Surgery: the biological basis of modern surgical practice 17th Edn.BRITISH JOURNAL OF SURGERY (NOW INCLUDES EUROPEAN JOURNAL OF SURGERY), Issue 4 2005No abstract is available for this article. [source] Handbook of Diabetes, 3rd ednDIABETIC MEDICINE, Issue 6 2005A. Advani No abstract is available for this article. [source] Alcohol: No Ordinary Commodity , a summary of the second editionADDICTION, Issue 5 2010Alcohol, Public Policy Group ABSTRACT This article summarizes the contents of Alcohol: No Ordinary Commodity (2nd edn). The first part of the book describes why alcohol is not an ordinary commodity, and reviews epidemiological data that establish alcohol as a major contributor to the global burden of disease, disability and death in high-, middle- and low-income countries. This section also documents how international beer and spirits production has been consolidated recently by a small number of global corporations that are expanding their operations in Eastern Europe, Asia, Africa and Latin America. In the second part of the book, the scientific evidence for strategies and interventions that can prevent or minimize alcohol-related harm is reviewed critically in seven key areas: pricing and taxation, regulating the physical availability of alcohol, modifying the drinking context, drink-driving countermeasures, restrictions on marketing, education and persuasion strategies, and treatment and early intervention services. Finally, the book addresses the policy-making process at the local, national and international levels and provides ratings of the effectiveness of strategies and interventions from a public health perspective. Overall, the strongest, most cost-effective strategies include taxation that increases prices, restrictions on the physical availability of alcohol, drink-driving countermeasures, brief interventions with at risk drinkers and treatment of drinkers with alcohol dependence. [source] Handbook of Cardiovascular Emergencies 2nd ednEMERGENCY MEDICINE AUSTRALASIA, Issue 3 2002Trevor Jackson MBBS FACEM No abstract is available for this article. [source] Emergency Medicine Diagnosis and Management 2nd ednEMERGENCY MEDICINE AUSTRALASIA, Issue 3 2002Stephen Dunjey FACEM No abstract is available for this article. [source] Handbook of Obstetric and Gynecological Emergencies, 2nd ednEMERGENCY MEDICINE AUSTRALASIA, Issue 2 2002David Taylor No abstract is available for this article. [source] Neurology and Trauma, 2nd edn.EUROPEAN JOURNAL OF NEUROLOGY, Issue 7 2009K. A. Jellinger No abstract is available for this article. [source] The Neurology of Eye Movements 4th edn.EUROPEAN JOURNAL OF NEUROLOGY, Issue 7 2009K. A. Jellinger No abstract is available for this article. [source] The Fainting Phenomenon: Understanding Why People Faint and What to do About It, 2nd ednEUROPEAN JOURNAL OF NEUROLOGY, Issue 9 2007K. A. Jellinger No abstract is available for this article. [source] Duchenne Muscular Dystrophy, 3rd ednEUROPEAN JOURNAL OF NEUROLOGY, Issue 4 2004K. A. Jellinger No abstract is available for this article. [source] Clinical electromyography nerve conduction studies, 3rd ednEUROPEAN JOURNAL OF NEUROLOGY, Issue 5 2003S.J. Oh No abstract is available for this article. [source] ESCOP Monographs: The Scientific Foundation for Herbal Medicinal Products (2nd edn)FOCUS ON ALTERNATIVE AND COMPLEMENTARY THERAPIES AN EVIDENCE-BASED APPROACH, Issue 1 2010E Ernst [source] Seeds: The Ecology of Regeneration in Plant Communities, 2nd ednGRASS & FORAGE SCIENCE, Issue 2 2001R. J. Pakeman [source] Public Health for the 21st Century: New Perspectives on Policy, Participation and Practice (2nd edn) , Edited by Judy Orme, Jane Powell, Pat Taylor and Melanie GreyHEALTH & SOCIAL CARE IN THE COMMUNITY, Issue 1 2008Joyce Halliday No abstract is available for this article. [source] Social Policy for Nurses and the Helping Professions (2nd edn) , By Stephen Peckham and Liz MeerabeauHEALTH & SOCIAL CARE IN THE COMMUNITY, Issue 1 2008Roger Watson No abstract is available for this article. [source] Thurlbeck's Pathology of the Lung, 3rd ednHISTOPATHOLOGY, Issue 2 2006H M Daran No abstract is available for this article. [source] Blood Cells: A Practical Guide, 3rd ednINTERNAL MEDICINE JOURNAL, Issue 1-2 2003D. Joshua No abstract is available for this article. [source] Effect of suction on the mechanical behaviour of iron ore rockINTERNATIONAL JOURNAL FOR NUMERICAL AND ANALYTICAL METHODS IN GEOMECHANICS, Issue 8 2005Dragan Grgic Abstract The effect of suction on the behaviour of iron ore has been studied from both physical and mechanical points of view. The porosity and the suction phenomena have been analysed using different experimental techniques. Uniaxial compressive tests on partially saturated samples have shown that the suction is responsible for strength and cohesion improvement. Considering the theory of partially saturated porous soils of Coussy and Dangla (Mécanique des sols non saturés (2002 edn). Hermès Science: 2002; 390), we have proposed a constitutive law for partially saturated iron ore. The real increase in the apparent cohesion due to the capillary attraction forces is overestimated if the yield function is written in terms of effective stresses. The effect of the capillary cohesion has been modelled with a function in the expression of the apparent cohesion of the yield function. The effect of suction on the mechanical behaviour has been represented in the effective stresses space and in the total stresses space like the Alonso model (Géotechnique 1990; 40:405,430). Copyright © 2005 John Wiley & Sons, Ltd. [source] Modeling, analysis and control of dynamic systems (2nd edn) by William J. Palm III, John Wiley & Sons, Inc., New York, 2004, ISBN 0-471-07370-9INTERNATIONAL JOURNAL OF ADAPTIVE CONTROL AND SIGNAL PROCESSING, Issue 4 2006K. Dhanalakshmi No abstract is available for this article. [source] Fruit and Vegetables , Harvesting, Handling and Storage, 2nd edn.INTERNATIONAL JOURNAL OF FOOD SCIENCE & TECHNOLOGY, Issue 9 2006Berat Nursal Tosun PhD No abstract is available for this article. [source] Validation of the Severe Impairment Battery for patients with Alzheimer's disease in KoreaINTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, Issue 7 2006Guk-Hee Suh Abstract Objective To examine the reliability and the validity of the Korean version of the SIB (SIB-K); and to determine its usefulness in patients with severe dementia. Methods Sixty-five patients (56 women, nine men) who lived in a nursing home and met the criteria of the Diagnostic and Statistical Manual of Mental Disorders, 4th edn, for the dementia of the Alzheimer's type were selected. Following clinical examination and evaluation using the Korean version of the Severe Impairment Battery (SIB-K), the Korean versions of the Mini-Mental State Examination (MMSE-K) and the cognitive subscale of the Alzheimer's Disease Assessment Scale (ADAS-K-cog) were applied as comparators. Results The mean scores on the SIB-K were 63.9 (SD,=,29.1), with a possible maximum of 100 points. Patients with MMSE scores from 0 to 4 points showed wide range of the SIB score from 4 to 62. The internal consistency of the SIB-K obtained by the Cronbach's alpha was 0.98. The inter-rater and test,retest reliabilities of the SIB-K obtained by the Spearman's rho were 0.99 and 0.97, respectively. Correlation between the SIB-K and the MMSE-K was 0.87, while correlation between the SIB-K and the ADAS-K-cog was ,0.76. Conclusions This study indicates that the Korean version of the SIB is a reliable, valid and useful test for measuring cognition of severely demented patients at a point where other conventional tests lose their sensitivity and show a floor effect. Copyright © 2006 John Wiley & Sons, Ltd. [source] Developing Effective Research Proposals, 2nd ednJOURNAL OF ADVANCED NURSING, Issue 6 2007Penny Franklin MA RN RCN RHV RNT No abstract is available for this article. [source] Clinically Oriented Anatomy, 6th edn.JOURNAL OF ANATOMY, Issue 4 2009Simon H. Parson No abstract is available for this article. [source] I-CAN: A New Instrument to Classify Support Needs for People with Disability: Part IJOURNAL OF APPLIED RESEARCH IN INTELLECTUAL DISABILITIES, Issue 4 2009Vivienne C. Riches Background, The supports paradigm has shifted focus from assessing competence and deficits among people with disabilities to identifying supports needed to live meaningful and productive lives in inclusive settings. Consequently, a rigorous and robust system is required that is capable of accurately determining the type and intensity of support needed and of allocating resources accordingly. The aim of the present study was to develop such a system to identify and classify support needs of people with disabilities based on the conceptual framework of the International Classification of Functioning, Disability and Health (ICF) [WHO, The International Classification of Functioning, Disability and Health (ICF), Author, Geneva, 2001], and the supports concept [Mental Retardation: Definition, Classification and Systems of Support, 9th edn (1992), 10th edn (2002), American Association on Mental Retardation, Washington, DC). Method, A total of 1012 individuals with disabilities who were supported by accommodation and day programme organizations across the eastern states of Australia were assessed. The instrument was used in a team setting involving the person, their family and friends and staff as appropriate. Version 1 was administered with 595 people with disability. This version was refined according to qualitative and quantitative analyses. Another 342 individuals were assessed using Version 2, resulting in a combined data set for 936 individuals. Version 3 was then trialled with a further 76 individuals with disabilities. Results, Ten domain scales in Health and Well Being (HWB) and Activities and Participation (A&P) were explored and refined. The scales effectively discriminated a range of intensities of support for people with various disabilities, with the highest support needs generally recorded by individuals with multiple disabilities who were ageing. The instrument can be used to develop a profile of needed supports across the domain scales. These measure current and predicted support needs, and contribute to future planning. The team approach proved beneficial in this regard. Conclusions, The I-CAN is a useful instrument for effectively assessing the support needs of people with a disability using a person centred approach. It is effective in identifying support needs across health and well-being areas, and activities of daily living. [source] Paul T. Williams waste treatment and disposal (2nd edn) John Wiley & Sons, England, 2005, 380 pp, £29.95, ISBN 0-470-84913-4JOURNAL OF APPLIED TOXICOLOGY, Issue 1 2006Liz Macquarrie No abstract is available for this article. [source] | ||||||||||||||||||||||||||||||||||||||||||||||||||||