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Selected AbstractsDisease burden of chronic lymphocytic leukaemia within the European UnionEUROPEAN JOURNAL OF HAEMATOLOGY, Issue 4 2008Louise Watson Abstract Objective:, Whilst Chronic lymphocytic leukaemia (CLL) is considered a rare disease, to our knowledge, the current prevalence of CLL within the European Union (EU) member states is not published. Understanding the number of individuals with CLL is vital to assess disease burden within the wider population. Methods:, Using 2002 data from the International Agency for Research on Cancer, we estimated the number of individuals with CLL (ICD-10 C91.1) from those reported for all leukaemias (C91,95) and extrapolated the figures by the population increase within the EU between 2002 and 2006, the last year with fully updated community population estimates. One- and 5-yr partial prevalence estimates are reported (i.e. the number of individuals still living 1,5 yr post-diagnosis). We then applied proportional estimates from the literature to assess those requiring immediate treatment, those under observation and their likely progression rates. Results:, We found that within the 27 EU states plus Iceland, Norway and Lichtenstein, 1- and 5-yr CLL partial prevalence estimates totalled approximately 13 952 and 46 633 individuals respectively in 2006. By applying Binet staging to the 1-yr estimate, 40% of patients will be stage B/C and require immediate treatment. Thus, 5581 individuals may be treated within the first year of diagnosis. Of the 60% (8371) under observation, by 5 yr up to 33% (2763) may have more advanced disease with increased risk of mortality. Conclusion:, Whilst CLL is a rare disease, the number of individuals burdened by the disease within the EU is considerable and thousands of patients require treatment and physician care, which has cost implications for member states. [source] The Importance of Actor Cleavages in Negotiating the European ConstitutionINTERNATIONAL STUDIES QUARTERLY, Issue 3 2010Madeleine O. Hosli This paper aims to explore government preferences and cleavages in the bargaining process on the European Constitution, across the range of 25 EU member states. The study focuses on preferences concerning socioeconomic policymaking and explores whether divisions can be discerned between preferences held by actors according to locations on the left-right policy scale, actors in older as compared to newer EU states, net EU budget positions, domestic rates of support for European integration, and smaller as compared to larger states. The analysis also controls for possible external effects, such as recent domestic macroeconomic developments. Negotiations on the European Constitution are found to be determined less by general transnational left-right divisions, but cleavages according to the length of EU membership and the size of EU member states. [source] The Nice Treaty and Voting Rules in the Council: A Reply to Moberg (2002)JCMS: JOURNAL OF COMMON MARKET STUDIES, Issue 3 2004Madeleine O. Hosli This response to Moberg (2002) demonstrates that some of his figures and calculations require more thorough analysis. His dismissal of the risk of inertia in the Council after enlargement, his measurement of blocking power of individual EU states and his figures on relative under- and over-representation of EU states in the Council are disputed. The article pleads for a dialogue between academics and practitioners in order to avoid random outcomes and ad hoc deals, such as those resulting from the political bargaining during the 2000 Nice summit meeting. Sound expert advice on voting rules and their effects is desirable for achieving more transparent, equitable and sensible institutional solutions, and allocation of voting weights and seats in the EU Council and Parliament. [source] The European Commission on Factors Influencing Labor MigrationPOPULATION AND DEVELOPMENT REVIEW, Issue 2 2001Article first published online: 27 JAN 200 A controversial issue in discussions on enlargement of the European Union beyond its existing membership of 15 countries is the migration flows that admission of new members could generate. Given major differences in income and wage levels between the EU states and the candidates for membership, casual theorizing suggests that the potential for massive international migration is very high. The fact that such migration has thus far been of modest size by most plausible criteria is attributed to the restrictive policies of the potential destination countries, policies that reflect national interests, in particular protection of labor markets, as perceived by voting majorities. With accession to membership in the EU this factor is removed: a cardinal principle of the Union, established by treaty, is the free movement of persons, including persons seeking gainful employment. The factors governing migratory movements between member states then come to resemble those that shape internal migration. This should facilitate analysis and forecasting. A clear sorting-out of the relevant forces affecting such "internal" migration remains of course an essential precondition for success in that task. An "Information note," entitled The Free Movement of Workers in the Context of Enlargement, issued by the European Commission, the EU's Executive Body, on 6 March 2001, presents extensive discussion of relevant information, opinion, and policy options concerning its topic. (The document is available at «http://europa.eu.int/comm/enlarge-ment/docs/pdf/migration_enl.pdf».) An Annex to the document. Factors Influencing Labour Movement, is a lucid enumeration of the factors migration theory considers operative in determining the migration of workers and, by extension, of people at large, that is likely to ensue upon EU enlargement. This annex is reproduced below. As is evident from the catalog of factors and their likely complex interactions, making quantitative forecasts of future migration flows, envisaged primarily as originating from countries to be newly admitted to the EU and destined for the countries of the current EU15, is exceedingly difficult. This is reflected in disparities among the existing studies that have made such forecasts. Yet there appears to be a fair degree of agreement that major increases in migration are unlikely, suggesting that the overall effect on the EU15 labor market should be limited. Typical forecasts (detailed in the Information note cited above) anticipate that in the initial year after admission, taken to be 2003, total migration from the eight prime candidate countries (the Czech Republic, Hungary, Poland, Slovakia, Slovenia, Estonia, Latvia, and Lithuania: the "CC8") might amount to around 200,000 persons, roughly one-third of which would be labor migration. According to these forecasts, the annual flow will gradually diminish in subsequent years. After 10 to 15 years the stock of CC8 migrants in the EU15 might be on the order of 1.8 to 2.7 million. The longer-run migration potential from the candidate countries would be on the order of 1 percent of the present EU population, currently some 375 million. (The combined current population of the CC8 is 74 million.) Such predictions are in line with the relatively minor migratory movements that followed earlier admissions to the EU of countries with then markedly lower per capita incomes, such as Spain and Portugal. The geographic impact of migration ensuing from enlargement would, however, be highly uneven, with Germany and Austria absorbing a disproportionately large share. Accordingly, and reflecting a prevailing expectation in these two countries that enlargement would have some short-run disruptive effects on labor markets, some of the policy options discussed envisage a period of transition following enlargement,perhaps five to seven years,during which migration would remain subject to agreed-upon restrictions. [source] Domestic abuse experienced by young people living in families with alcohol problems: results from a cross-european studyCHILD ABUSE REVIEW, Issue 6 2008Richard Velleman Abstract This paper presents findings from the European Union (EU) DAPHNE project ALC-VIOL (2005,07). The project involved ten EU states (Germany, Austria, England, Finland, Hungary, Ireland, Malta, Netherlands, Poland and Spain). The research involved interviews with young people aged 12,18 from Germany, Poland, Spain, England and Malta on their experiences of living with parental alcohol misuse and parental violence. The children all had parents involved in treatment for alcohol problems. The study highlights the stressful experiences these children underwent, the effects on them, their coping strategies, and the support that they received and/or wished for, and underlines the need for a more coherent approach to help these children. Copyright © 2008 John Wiley & Sons, Ltd. [source] |