Duncan's Multiple Range Test (duncan + multiple_range_test)

Distribution by Scientific Domains


Selected Abstracts


Diffusion of reduced arecoline and arecaidine through human vaginal and buccal mucosa

JOURNAL OF ORAL PATHOLOGY & MEDICINE, Issue 4 2001
P. Van der Bijl
Abstract: Because alkaloids from areca nut, arecoline and arecaidine, have been implicated in the development of oral submucous fibrosis, we determined their diffusion kinetics through human buccal and vaginal mucosa. Four clinically healthy vaginal mucosa specimens (mean patient age± standard deviation: 47±15 years; age range: 31,60 years) and 4 buccal mucosa specimens from 2 male patients and 2 female patients (mean patient age±standard deviation: 31±9 years; age range: 17,53 years) were obtained during surgery. In vitro flux rates of reduced arecoline and arecaidine (r-arecoline and r-arecaidine) were determined by use of a flow-through diffusion apparatus. Analysis of variance, a Duncan multiple range test, and an unpaired t -test were used to determine steady state kinetics and flux differences over time intervals. Although statistically significant differences were observed between flux values for both alkaloids and tissues at certain time points, these were not considered to be of biological (clinical) significance. However, the flux rates across both mucosa of r-arecoline were significantly higher statistically than those of r-arecaidine. The findings demonstrated the differences in the diffusion kinetics between r-arecoline and r-arecaidine across human buccal and vaginal mucosa, an observation that could be explained in terms of their ionisation characteristics. Additionally, the results obtained further support the hypothesis that human vaginal mucosa can be used as a model for buccal mucosa in studies of permeability to various chemical compounds. [source]


Structural patterns in coarse gravelriver beds: typology, survey and assessment of the roles of grain size and river regime

GEOGRAFISKA ANNALER SERIES A: PHYSICAL GEOGRAPHY, Issue 1 2002
Lea Wittenberg
The concept of river-bed stability as indexed by the occurrence of stable bed forms was examined in humid-temperate perennial streams and in Mediterranean ephemeral streams. The study examined the structural patterns of bed forms and their spatial distribution between temperate-humid and Mediterranean streams. Study sites in Northumberland, UK, and Mt. Carmel, Israel, were selected for their morphometric similarity, despite the contrast in climate, vegetation and hydrological regime. Fieldwork was based on a large number of Wolman grain size distributions and structure measurements along cross-sections at seven sites; Differences in mean grain size of bed structures were estimated using the general linear model (GLM) procedure and Duncan's multiple range test. Based on field evidence, river-bed configurations were divided into structural categories, according to the depositional setting of each measured particle on the river bed. Statistical analysis confirmed former qualitative descriptions of small-scale bed forms. The study identified spatial segregation in bed form distribution. In general, 30,40%of the bed material in the surveyed perennial streams was clustered, in contrast to approximately 10%in the ephemeral counterparts. The sorting index revealed higher values for the perennial streams, namely 2.39,3.59 compared with 1.73,2.07 for the ephemeral counterparts. It is suggested that the degree of sediment sorting and the proportion of clusters are strongly related. Sediment sorting, sediment supply and the hydrological regime explain the mechanism of cluster formation. It is assumed that climate shifts or human interference within river basins might affect the regional characteristic flood hydrograph, and consequently alter the sedimentary character of the river bed. In the case where river bed stability is reduced owing to changes in cluster bed form distribution, rivers that normally do not yield a significant amount of sediment might be subject to notable sedimentation problems. [source]


Determination of biochemical properties of foam-mat dried mango powder

INTERNATIONAL JOURNAL OF FOOD SCIENCE & TECHNOLOGY, Issue 8 2010
Dattatreya M. Kadam
Summary Investigations were carried out to see the impact of drying air temperature (65, 75 and 85 °C) and milk as foaming agent in different concentration levels (0%, 10%, 15%, 20% and 25%) on the chemical properties of foam-mat dried mango juice powder. Chemical properties such as total sugars, ascorbic acid, total carotenes, minerals, total acid, pH, total soluble solids (TSS) and microbial load (fungal and bacterial) of foam-mat dried mango powder were determined. Data were analysed as per two-way anova, Duncan's multiple range test and l.s.d. of AgRes Software statistical package. Almost all chemical properties show decreasing trend with increase in drying air temperature. Microbial load was not detected in foam-mat dried mango powder. It was found that addition of 10% milk as foaming agent and drying at 65 °C temperature gave better results. [source]


Antioxidant enzyme levels in oral squamous cell carcinoma and normal human oral epithelium

JOURNAL OF ORAL PATHOLOGY & MEDICINE, Issue 2 2002
J. Yang
Abstract Background:, The antioxidant enzymes (manganese- and copper-zinc-containing superoxide dismutases, catalast and glutathione peroxidase) limit cell injury induced by reactive oxygen species. The purpose of the study was to determine whether human oral squamous cell carcinomas have altered antioxidant enzyme levels. This study is the first to undertake this task in human oral mucosa and squamous cell carcinoma. Methods:, Semiquantitative immunohistochemistry was used to examine 26 archived oral squamous cell carcinoma biopsies. Fourteen well-differentiated and 12 poorly differentiated tumors were examined, as were 12 specimens of oral mucosa. All sections were reviewed by two oral and maxillofacial pathologists, and image analysis of the immunostained sections was performed using NIH Image. Antioxidant enzyme staining intensities were compared in the different groups by Duncan's multiple range test. Results:, In general, mucosal basal cells displayed lower antioxidant enzyme levels than spinous cells, and primary tumor cells displayed lower antioxidant enzyme staining intensities than did their normal cell counterparts. Moreover, poorly differentiated tumor cells showed lower antioxidant enzyme staining intensities than well-differentiated tumor cells. Manganese-containing superoxide dismutase staining intensities were, however, higher in well-differentiated oral squamous cell carcinomas than their normal cells of origin. Conclusions:, Detection of antioxidant enzymes may be a useful future marker in the molecular diagnosis of the oral cancer. Moreover, it may be possible to not only monitor the effectiveness of chemopreventitive and therapeutic strategies in oral cancer using these enzymes, but to monitor tumor recurrence. [source]


Fluoride release and uptake characteristics of aesthetic restorative materials

JOURNAL OF ORAL REHABILITATION, Issue 8 2002
N. Attar
Summary The aims of this study were firstly to investigate the fluoride-releasing characteristics of two composite resins (Tetric and Valux Plus), two polyacid-modified resin composites (Compoglass and Dyract), and conventional glass,ionomer cement (Ceramfil ,). The second aim was to assess the fluoride uptake and subsequent release from the same range of materials. Fifteen discs (6 mm diameter and 1·5 mm height) were prepared for each material. Each disc was immersed in 4 ML of deionized water within a plastic vial. The release of fluoride was measured daily at 1, 2, 3, 4, 5, 15, 30 and 60 days. After daily fluoride release was measured for 60 days, samples were refluoridated in 1000-ppm sodium fluoride (NaF) solutions (pH 6·6) for 10 min and fluoride release was measured daily for a total of 5 days. The release of fluoride from aesthetic restorative materials was measured by using specific fluoride electrode and an ionanalyser. Results were statistically analysed by two-way repeated measure ANOVA and Duncan's multiple range test. The results revealed that all fluoride-containing materials (Ceramfil ,, Compoglass, Dyract, Tetric) released fluoride initially and the release was greatest at the first day. At any time during the test period Ceramfil , released the most and Valux Plus did not release any detectable fluoride (P < 0·01). Sample exposures to 1000 ppm NaF solution increased the 24-h fluoride release from all fluoride-containing materials. This difference lasted only 24,48 h after exposure. Ceramfil , had a tendency to recharge not seen with the other materials (P < 0·05). [source]


A compliant tip reduces the peak pressure of laparoscopic graspers

ANZ JOURNAL OF SURGERY, Issue 7 2002
Damian D. Marucci
Background: Previous studies have demonstrated that high pressures are generated at the tips of laparoscopic graspers, which can cause tissue injury. This study examines the effect of a compliant edge on tip pressure. Methods: One of a pair of identical laparoscopic graspers was modified by refashioning the tip out of silicone. A thin film pressure transducer (I-scan 6900 sensor) was deployed between the jaws of the grasper and a simulated tissue (leather strap). Load and handle pressures were kept constant. Peak tip pressure readings were taken as the load orientation was increased from the perpendicular to 135° (n = 10). The data was analysed using anova and a post-hoc Duncan's multiple range test. Results: Peak tip pressures generated by the compliant tipped grasper were significantly less than those developed by the unmodified grasper, particularly at high-load orientations. Conclusion: High pressures generated at the tip of laparoscopic graspers can be reduced by altering the mechanical properties (compliance) of the tip. [source]