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Different Evolutionary Histories (different + evolutionary_history)

Distribution by Scientific Domains
Life Sciences75%

Selected Abstracts

Different Evolutionary Histories of the Coagulation Factor VII Gene in Human Populations?

ANNALS OF HUMAN GENETICS, Issue 1 2010
Georgios Athanasiadis
Summary Immoderate blood clotting constitutes a risk factor for cardiovascular disease in modern industrialised societies, but is believed to have conferred a survival advantage, i.e. faster recovery from bleeding, on our ancestors. Here, we investigate the evolutionary history of the Coagulation Factor VII gene (F7) by analysing five cardiovascular-risk-associated mutations from the F7 promoter and nine neutral polymorphisms (six SNPs and three microsatellites) from the flanking region in 16 populations from the broader Mediterranean region, South Saharan Africa and Bolivia (687 individuals in total). Population differentiation and selection tests were performed and linkage disequilibrium patterns were investigated. In all samples, no linkage disequilibrium between adjacent F7 promoter mutations ,402 and ,401 was observed. No selection signals were detected in any of the samples from the broader Mediterranean region and South Saharan Africa, while some of the data suggested a potential signal of positive selection for the F7 promoter in the Native American samples from Bolivia. In conclusion, our data suggest, although do not prove, different evolutionary histories in the F7 promoter region between Mediterraneans and Amerindians. [source]

Quantitative analysis of InSAR digital elevation models for identification of areas with different tectonic activities in southern Italy

EARTH SURFACE PROCESSES AND LANDFORMS, Issue 1 2009
Claudio Martino
Abstract This work presents the results of a quantitative analysis of an interferometric SAR (InSAR) digital elevation model (DEM), obtained by the Shuttle Radar Topography Mission (SRTM). The analysis aims to identify additional parameters to recognize areas in southern Italy with different tectonic activities and behaviours. The axial zone of the Campania-Lucania Apennine and the Sila Massif in Calabria, Italy, characterized by quite different evolutionary histories, have been chosen as test areas sufficiently wide to validate observations on a sub-regional scale at least. Geomorphological information on the shape of palaeosurfaces has been used to estimate uplift and/or erosion amounts and rates. Palaeosurfaces are identified on the DEM as regions with an altitude higher than 1000 m a.s.l. and sub-planar land surfaces dipping less than 6°. Information about the shape of palaeosurfaces during the first stage of uplift and before the tectonic-induced block fragmentation has been extracted. A fragmentation index has been computed for these erosional surfaces. The first stage of this landscape evolution has been studied in terms of the geometric characteristics of fragmented blocks. The last erosional stage has been recognized in terms of both geometric characteristics and fragmentation index of the sub-horizontal land surfaces. Altitude and age of the palaeosurfaces, referred to ancient base-levels of the erosion, have been used to estimate the erosional rate. Copyright © 2008 John Wiley and Sons, Ltd. [source]

Different Evolutionary Histories of the Coagulation Factor VII Gene in Human Populations?

ANNALS OF HUMAN GENETICS, Issue 1 2010
Georgios Athanasiadis
Summary Immoderate blood clotting constitutes a risk factor for cardiovascular disease in modern industrialised societies, but is believed to have conferred a survival advantage, i.e. faster recovery from bleeding, on our ancestors. Here, we investigate the evolutionary history of the Coagulation Factor VII gene (F7) by analysing five cardiovascular-risk-associated mutations from the F7 promoter and nine neutral polymorphisms (six SNPs and three microsatellites) from the flanking region in 16 populations from the broader Mediterranean region, South Saharan Africa and Bolivia (687 individuals in total). Population differentiation and selection tests were performed and linkage disequilibrium patterns were investigated. In all samples, no linkage disequilibrium between adjacent F7 promoter mutations ,402 and ,401 was observed. No selection signals were detected in any of the samples from the broader Mediterranean region and South Saharan Africa, while some of the data suggested a potential signal of positive selection for the F7 promoter in the Native American samples from Bolivia. In conclusion, our data suggest, although do not prove, different evolutionary histories in the F7 promoter region between Mediterraneans and Amerindians. [source]

Influence of genotype and geography on shell shape and morphometric trait variation among North Atlantic blue mussel (Mytilus spp.) populations

BIOLOGICAL JOURNAL OF THE LINNEAN SOCIETY, Issue 4 2009
JONATHAN P. A. GARDNER
The influence of geography and genotype on shell shape (outline) and trait (morphometric) variation among North Atlantic blue mussels and their hybrids has been examined. Shape differences among reference taxa (Mytilus trossulus, Mytilus edulis and Mytilus galloprovincialis) were consistent with an association between taxon-specific genes and shape genes. Newfoundland M. edulis × M. trossulus populations and northern Quebec M. trossulus populations exhibited an uncoupling of taxon-specific genes from shape genes, whereas Nova Scotia M. trossulus populations and SW England M. edulis × M. galloprovincialis populations exhibited an association between taxon-specific genes and shape genes. We found no evidence of a geographic effect (NE versus NW Atlantic) for shape variation, indicating that the genotype effect is stronger than any geographic effect at macrogeographic scales. Pronounced differences were observed in trait variability consistent with an association between taxon-specific genes and trait genes in European populations, and trait divergence of New York M. edulis from all European mussels. Trait variability in mussels from Newfoundland, Nova Scotia and northern Quebec indicated an uncoupling of taxon genes from trait genes, whereas trait variability in SW England M. edulis × M. galloprovincialis populations was consistent with background genotype, indicating a strong association between taxon genes and trait genes. A pronounced macrogeographic split (NE versus NW Atlantic) regardless of taxonomy was observed, indicating that geography exerts a greater influence than genotype on trait variation at the macrogeographic scale. This is consistent with pronounced within-taxon genetic divergence, indicative of different selection regimes or more likely of different evolutionary histories of mussels on either side of the North Atlantic. © 2009 The Linnean Society of London, Biological Journal of the Linnean Society, 2009, 96, 875,897. [source]