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Diazo Ester (diazo + ester)
Selected AbstractsChiral and Flexible 2,4-Pentanediol-Tethered Cyclopropanation of Olefins with a Carbenoid Derived from a Diazo Ester to Construct Three Stereogenic Centers.CHEMINFORM, Issue 31 2003Takashi Sugimura No abstract is available for this article. [source] Novel Approach to Arylhydrazones, the Precursor for Fischer Indole Synthesis, via Diazo Esters Derived from ,-Amino Acid Esters.CHEMINFORM, Issue 17 2006Eiko Yasui Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Stereoselective Synthesis of Multifunctionalized 1,2,4-Triazolidines by a Ruthenium Porphyrin-Catalyzed Three-Component Coupling ReactionADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 16-17 2006Ming-Zhong Wang Abstract Multifunctionalized 1,2,4-triazolidines have been synthesized by a ruthenium porphyrin-catalyzed three-component coupling reaction. In a one-pot reaction, ruthenium porphyrins catalyzed the in situ generation of azomethine ylides from ,-diazo esters and imines. Stereoselective 1,3-dipolar cycloaddition reactions of the azomethine ylides with dialkyl azodicarboxylates gave the corresponding 1,2,4-triazolidines in good yields (up to 85,%). Using chiral 8-phenylmenthanol ,-diazo ester as the carbenoid source, chiral 1,2,4-triazolidines have been obtained with good diastereoselectivity (up to 84,% de). Some of the 1,2,4-triazolidines exhibited good cytotoxicity against human nasopharyngeal carcinoma (SUNE1) (IC50=10.4,,M) and human cervical carcinoma (Hela) (IC50=10.7,,M) cell lines. [source] | ||||||||||