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Developing World (developing + world)
Selected AbstractsCLINICAL TRIALS AND SCID ROW: THE ETHICS OF PHASE 1 TRIALS IN THE DEVELOPING WORLDDEVELOPING WORLD BIOETHICS, Issue 3 2007JONATHAN KIMMELMAN ABSTRACT Relatively little has been written about the ethics of conducting early phase clinical trials involving subjects from the developing world. Below, I analyze ethical issues surrounding one of gene transfer's most widely praised studies conducted to date: in this study, Italian investigators recruited two subjects from the developing world who were ineligible for standard of care because of economic considerations. Though the study seems to have rendered a cure in these two subjects, it does not appear to have complied with various international guidelines that require that clinical trials conducted in the developing world be responsive to their populations' health needs. Nevertheless, policies devised to address large scale, late stage trials, such as the AZT short-course placebo trials, map somewhat awkwardly to early phase studies. I argue that interest in conducting translational research in the developing world, particularly in the context of hemophilia trials, should motivate more rigorous ethical thinking around clinical trials involving economically disadvantaged populations. [source] DEFINING STANDARD OF CARE IN THE DEVELOPING WORLD: THE INTERSECTION OF INTERNATIONAL RESEARCH ETHICS AND HEALTH SYSTEMS ANALYSISDEVELOPING WORLD BIOETHICS, Issue 2 2005ADNAN A. HYDER ABSTRACT In recent years there has been intense debate regarding the level of medical care provided to ,standard care' control groups in clinical trials in developing countries, particularly when the research sponsors come from wealthier countries. The debate revolves around the issue of how to define a standard of medical care in a country in which many people are not receiving the best methods of medical care available in other settings. In this paper, we argue that additional dimensions of the standard of care have been hitherto neglected, namely, the structure and efficiency of the national health system. The health system affects locally available medical care in two important ways: first, the system may be structured to provide different levels of care at different sites with referral mechanisms to direct patients to the appropriate level of care. Second, inefficiencies in this system may influence what care is available in a particular locale. As a result of these two factors locally available care cannot be equated with a national ,standard'. A reasonable approach is to define the national standard of care as the level of care that ought to be delivered under conditions of appropriate and efficient referral in a national system. This standard is the minimum level of care that ought to be provided to a control group. There may be additional moral arguments for higher levels of care in some circumstances. This health system analysis may be helpful to researchers and ethics committees in designing and reviewing research involving standard care control groups in developing country research. [source] CENTRALIZED AND DECENTRALIZED MANAGEMENT OF LOCAL COMMON POOL RESOURCES IN THE DEVELOPING WORLD: EXPERIMENTAL EVIDENCE FROM FISHING COMMUNITIES IN COLOMBIAECONOMIC INQUIRY, Issue 2 2010MARIA ALEJANDRA VELEZ This article uses experimental data to test for a complementary relationship between formal regulations imposed on a community to conserve a local natural resource and nonbinding verbal agreements to do the same. Our experiments were conducted in the field in three regions of Colombia. Our results suggest that the hypothesis of a complementary relationship between communication and external regulation is supported for some combinations of regions and regulations but cannot be supported in general. We conclude that the determination of whether formal regulations and informal communication are complementary must be made on a community-by-community basis. (JEL C93, H41, Q20, Q28) [source] The Nutrition Transition in the Developing WorldDEVELOPMENT POLICY REVIEW, Issue 5-6 2003Barry M. Popkin This article explores shifts in nutrition transition from the period termed the receding famine pattern to one dominated by nutrition-related noncommunicable diseases (NR-NCDs). It examines the speed of these changes, summarises dietary and physical activity changes, and provides some sense of the health effects and economic costs. The focus is on the lower- and middle-income countries of Asia, Africa, the Middle East and Latin America. The article shows that changes are occurring at great speed and at earlier stages of countries' economic and social development. The burden of disease from NR-NCDs is shifting towards the poor and the costs are also becoming greater than those for under-nutrition. Policy options are identified. [source] Book Reviews: Distribution and Development: A New Look at the Developing WorldECONOMICA, Issue 282 2004Rohini Somanathan No abstract is available for this article. [source] The Interdependence of U.S. Troop Deployments and Trade in the Developing WorldFOREIGN POLICY ANALYSIS, Issue 3 2009Glen Biglaiser The relationship between political conflict and trade has contributed to a riveting discussion in international relations about whether trade produces conflict, or whether conflict itself reduces trade. Most studies proxy "the flag" using militarized interstate disputes (MIDs). However, extensions of "the flag" might well obtain in environments short of MIDs. A more general way to proxy the flag is troop deployments. The deployment of military troops is an essential element of foreign policy. Using panel data for 126 developing countries from 1965 to 2002 and a two-stage least square approach, this essay investigates the relationship between trade and United States troop deployments. We find that trade and troops have a nonrecursive relationship: trade follows the flag and troops follow trade. Given the increased insecurity in the world today, the results are timely and reinforce previous research about the reciprocal relationship between the flag and trade. [source] Investing Public Pensions in the Stock Market: Implications for Risk Sharing, Capital Formation and Public Policy in the Developed and Developing WorldINTERNATIONAL REVIEW OF FINANCE, Issue 3 2001Deborah Lucas Concerns that existing public pension systems will be unable to pay benefits to a rapidly ageing population without sharp tax increases, and the prospect of higher average returns on stocks than on government securities, are drawing the attention of policy,makers worldwide to the option of investing public pension assets in stocks. Including stock market investments in public pension plans could improve risk sharing within and between generations, and could perhaps lead to faster market development in some countries. It could also result in excessive risk,taking, higher transactions costs and a false sense of increased financial security. This paper assesses these issues, with an emphasis on the considerations that are of special importance to developing markets. A contrast is drawn between the demographic outlook in East Asia and the major industrialized countries. Some lessons are drawn from the reform experience in Chile and elsewhere in Latin America. [source] Critical Perspectives on Schooling and Fertility in the Developing World, by Caroline Bledsoe,John Casterline, Jennifer Johnson-Kuhn and John Haaga (eds).JOURNAL OF INTERNATIONAL DEVELOPMENT, Issue 8 2000National Academy Press, Washington DC, pp.x + 320.Reviewed by Abbi Mamo Kedir. No abstract is available for this article. [source] Responding to Women's HIV and STI Risk in the Developing WorldJOURNAL OF OBSTETRIC, GYNECOLOGIC & NEONATAL NURSING, Issue 5 2008Suellen Miller Guest Editor No abstract is available for this article. [source] Delivering Public Services in the Developing World: Frontiers of ResearchOXONOMICS, Issue 1 2009Daniel Rogger This essay presents a view of the frontiers of research on public service delivery in the developing world, based on a series of interviews with researchers and practitioners actively working in this field. It recognizes the lasting contribution of the theoretical framework laid down by the World Development Report 2004 that emphasized accountability, and the randomized evaluations that have taken place to test and develop this theory. Research on other questions, such as those relating to the analysis of politics and the structure and organization of government, is at an earlier stage, and is likely to need a more structural approach. There are many questions still to be answered in this field. [source] On the Determinants of Mortality Reductions in the Developing WorldPOPULATION AND DEVELOPMENT REVIEW, Issue 2 2007Rodrigo R. Soares This article presents and critically discusses evidence on the determinants of mortality reductions in developing countries. It argues that increases in life expectancy between 1960 and 2000 were largely independent of improvements in income. The author characterizes the age and cause-of-death profile of changes in mortality and assesses what can be learned about the determinants of these changes from the international evidence and from country-specific studies. Public health infrastructure, immunization, targeted programs, and the spread of less palpable forms of knowledge all seem to have been important factors. Finally, the article suggests that the evolution of health inequality across and within countries is intrinsically related to the process of diffusion of new technologies and to the nature of these new technologies, public or private. [source] Globalization and the Strengthening of Democracy in the Developing WorldAMERICAN JOURNAL OF POLITICAL SCIENCE, Issue 4 2005Nita Rudra Scholars and policy makers have long assumed that trade and financial liberalization encourages developing countries to become more democratic; yet no one has developed formal hypotheses about the causal relationship between globalization and democracy. This article shows that these two trends are indeed related, but not necessarily in the direct manner that has commonly been postulated. Combining theories of embedded liberalism and conflict-based theories of democracy, the model presented here depicts the process that affects decisions to strengthen democracy as trade and capital flows increase. I argue that increasing exposure to international export and financial markets leads to improvements in democracy if safety nets are used simultaneously as a strategy for providing stability and building political support. Empirical evidence is provided by econometric analysis covering 59 developing countries for the time period 1972,97. [source] Overview: End-Stage Renal Disease in the Developing WorldARTIFICIAL ORGANS, Issue 9 2002Rashad S. Barsoum Abstract: Although the vast majority of patients with end-stage renal disease (ESRD) worldwide live in what is called the developing world, little is known about its epidemiology and management. With the current paucity of credible and adequately representative registries, it is justified to resort to innovative means of obtaining information. In this attempt, world-renowned leading nephrologists in 10 developing countries collaborated in filling a 103-item questionnaire addressing epidemiology, etiology, and management of ESRD in their respective countries on the basis of integrating available data from different sources. Through this joint effort, it was possible to identify a number of important trends. These include the expected high prevalence of ESRD, despite the limited access to renal replacement therapy, and the dependence of prevalence on wealth. Glomerulonephritis, rather than diabetes, remains as the main cause of ESRD with significant geographical variations in the prevailing histopathological types. The implementation of different modalities of renal replacement therapy (RRT) is inhibited by the lack of funding, although governments, insurance companies, and donations usually constitute the major sponsors. Hemodialysis is the preferred modality in most countries with the exception of Mexico where chronic ambulatory peritoneal dialysis (CAPD) takes the lead. In several other countries, dialysis is available only for those on the transplant waiting list. Dialysis is associated with a high frequency of complications particularly HBV and HCV infections. Data on HIV are lacking. Aluminum intoxication remains as a major problem in a number of countries. Treatment withdrawal is common for socioeconomic reasons. Transplantation is offered to an average of 4 per million population (pmp). Recipient exclusion criteria are minimal. Donor selection criteria are generally loose regarding tissue typing, remote viral infection, and, in some countries, blood-relation to the recipient in live-donor transplants. Cadaver donors are accepted in many countries participating in this survey. Treatment outcomes with different RRT modalities are, on the average, inferior to the internationally acknowledged standards largely due to infective and cardiovascular complications. [source] Emergency Medicine in the Developing World: A Delphi StudyACADEMIC EMERGENCY MEDICINE, Issue 7 2010Peter W. Hodkinson MPhil(EM) ACADEMIC EMERGENCY MEDICINE 2010; 17:765,774 © 2010 by the Society for Academic Emergency Medicine Abstract Objectives:, Emergency medicine (EM) as a specialty has developed rapidly in the western world, but remains largely immature in developing nations. There is an urgent need for emergency services, but no clear guidelines are available on the priorities for establishing EM in the developing world. This study seeks to establish consensus on key areas of EM development in developing world settings, with respect to scope of EM, staffing needs, training requirements, and research priorities. Methods:, A three-round Delphi study was conducted via e-mail. A panel was convened of 50 EM specialists or equivalent, with experience in or interest in EM in the developing world. In the first round, panelists provided free-text statements on scope, staffing, training, and research priorities for EM in the developing world. A five-point Likert scale was used to rate agreement with the statements in Rounds 2 and 3. Consensus statements are presented as a series of synopsis statements for each of the four major themes. Results:, A total of 168 of 208 statements (81%) had reached consensus at the end of the study. Key areas in which consensus was reached included EM being a specialist-driven service, with substantial role for nonphysicians. International training courses should be adapted to local needs. EM research in developing countries should be clinically driven and focus on local issues of importance. Conclusions:, The scope and function of EM and relationships with other specialties are defined. Unambiguous principles are laid out for the development of the specialty in developing world environments. The next step required in this process is translation into practical guidelines for the development of EM in developing world settings where they may be used to drive policy, protocols, and research. [source] CLINICAL TRIALS AND SCID ROW: THE ETHICS OF PHASE 1 TRIALS IN THE DEVELOPING WORLDDEVELOPING WORLD BIOETHICS, Issue 3 2007JONATHAN KIMMELMAN ABSTRACT Relatively little has been written about the ethics of conducting early phase clinical trials involving subjects from the developing world. Below, I analyze ethical issues surrounding one of gene transfer's most widely praised studies conducted to date: in this study, Italian investigators recruited two subjects from the developing world who were ineligible for standard of care because of economic considerations. Though the study seems to have rendered a cure in these two subjects, it does not appear to have complied with various international guidelines that require that clinical trials conducted in the developing world be responsive to their populations' health needs. Nevertheless, policies devised to address large scale, late stage trials, such as the AZT short-course placebo trials, map somewhat awkwardly to early phase studies. I argue that interest in conducting translational research in the developing world, particularly in the context of hemophilia trials, should motivate more rigorous ethical thinking around clinical trials involving economically disadvantaged populations. [source] POPULATION AGING AND INTERNATIONAL DEVELOPMENT: ADDRESSING COMPETING CLAIMS OF DISTRIBUTIVE JUSTICEDEVELOPING WORLD BIOETHICS, Issue 1 2007MICHAL ENGELMAN ABSTRACT To date, bioethics and health policy scholarship has given little consideration to questions of aging and intergenerational justice in the developing world. Demographic changes are precipitating rapid population aging in developing nations, however, and ethical issues regarding older people's claim to scarce healthcare resources must be addressed. This paper posits that the traditional arguments about generational justice and age-based rationing of healthcare resources, which were developed primarily in more industrialized nations, fail to adequately address the unique challenges facing older persons in developing nations. Existing philosophical approaches to age-based resource allocation underemphasize the importance of older persons for developing countries and fail to adequately consider the rights and interests of older persons in these settings. Ultimately, the paper concludes that the most appropriate framework for thinking about generational justice in developing nations is a rights-based approach that allows for the interests of all age groups, including the oldest, to be considered in the determination of health resource allocation. [source] Falling Apart at the Margins?DEVELOPMENT AND CHANGE, Issue 5 2009Neighbourhood Transformations in Peri-Urban Chennai ABSTRACT This article explores the peri-urban dynamics in developing cities using a theoretical examination of the metropolis as the new urban condition. Although a western conceptualization, the notion of the metropolis, and particularly metropolitan planning, was exported to the developing world to address its urbanization problems. Metropolitan development authorities were established for wider city regions and accorded legislative powers to prepare master plans for the metropolitan areas. However, in most instances, their planning strategies resulted in a conflation of the urban,rural interface into a more complex peri-urban condition, marked by heterogeneity and fragmentation. The article illustrates this through an empirical investigation in the Indian city of Chennai, where socio-spatial transformations of two borderland neighbourhoods on its southern periphery are assessed mainly in terms of metropolitan planning decisions over the decades. In outlining their metamorphosis, the study is careful not to perceive such conflicts as simple forms of polarization between the rich and the poor. Rather, it sets the class conflicts against the politico-economic dynamics yielding newer forms of polarization in the peri-urban spaces. [source] Global Environmental Governance and the Challenge of Shadow States: The Impact of Illicit Sapphire Mining in MadagascarDEVELOPMENT AND CHANGE, Issue 5 2005Rosaleen Duffy The environment has become a key site of global governance because of its transboundary nature: forests, wildlife and oceans have all become central foci for networks of global governance which link international organizations, international financial institutions, states and non-governmental organizations. This article examines how contemporary forms of global governance can be challenged and even subverted. It uses the concept of shadow states introduced by William Reno to explore how invisible global networks flow through developing states, to show how they constitute important political and economic interest groups, and to assess what kinds of environmental impact they have. It explores how powerful these networks are, and whether they are able to challenge or subvert attempts to manage, control or govern the environment. The author provides an analysis of the ways in which the clandestine networks of shadow states impact on conservation initiatives in the developing world, focusing on the features of global environmental governance and the problems posed by illicit gem mining and trafficking in Madagascar. [source] In Situ Urbanization in Rural China: Case Studies from Fujian ProvinceDEVELOPMENT AND CHANGE, Issue 2 2000Yu Zhu In most parts of the developing world, the urbanization process has been dominated by rural,urban migration and the growth of existing cities. However, case-studies in China's Fujian Province suggest that this process can also be achieved mainly by in situ transformation in rural areas. Such in situ transformation of rural areas has been driven mainly by two forces, the development of township and village enterprises (TVEs) and the inflow of foreign investment; and facilitated by the relevant policies adopted by the Chinese government since 1978. The former has been very effective in the transformation of rural employment structure, while the latter has brought many physical changes to the previously rural landscape. Being mutually complementary, these two ways of rural transformation have not only benefited and urbanized the rural areas, but kept many farmers in their hometowns, replacing the dominant role of rural,urban migration and the growth of existing cities in the urbanization process. [source] Reducing Child Labour Through Conditional Cash Transfers: Evidence from Nicaragua's Red de Protección SocialDEVELOPMENT POLICY REVIEW, Issue 6 2010Kevin A. Gee Conditional Cash Transfer (CCT) programmes, providing eligible households with periodic cash payments, contingent on their children's adherence to school enrolment and attendance requirements, hold considerable promise for reducing levels of child labour across the developing world. This article presents the results of an analysis of a CCT programme in Nicaragua, Red de Protección Social, and compares them with those of other CCT programmes, discussing how the structure of each programme's incentives, including differences in targeting, subsidy amounts and educational requirements, contributes to the variation in their effectiveness at reducing child labour. [source] Food Industrialisation and Food Power: Implications for Food GovernanceDEVELOPMENT POLICY REVIEW, Issue 5-6 2003Tim Lang Food supply chains of developed countries industrialised in the second half of the twentieth century, with significant implications for developing countries over policy priorities, the ensuing external costs and the accompanying concentration of market power. Very powerful corporations dominate many sectors. Primary producers are locked into tight specifications and contracts. Consumers may benefit from cheaper food but there are quality implications and health externalities. As consumer confidence has been shaken, new quality agencies have been created. Tensions have emerged about the state's role as facilitator of industrial efficiencies. Food policy is thus torn between the pursuit of productivity and reduced prices and the demand for higher quality, with implications for both producers and consumers in the developing world. [source] Social Protection: Defining the Field of Action and PolicyDEVELOPMENT POLICY REVIEW, Issue 5 2002Andy Norton This article reviews recent developments in the concept of social protection, beginning with an attempt to establish a working definition of the term. This is set in the context of globalisation and new thinking on connections between the management of vulnerability, risk and poverty on the one hand and long,term economic and social development on the other. The article identifies aspects of the debate which require further development, by exploring the relationship between social protection, equality, social cohesion and rights. It also reviews contemporary definitions of social protection in the policies of donors and international organisations, and summarises lessons to be learnt from experience to date with civil society practices and state policies in the developing world. [source] The therapeutics of lifestyle management on obesityDIABETES OBESITY & METABOLISM, Issue 11 2010P. A. Dyson The global incidence and prevalence of obesity continue to increase, with the fastest rate of increase in the developing world. Obesity is associated with many chronic diseases including type 2 diabetes, cardiovascular disease and some cancers. Weight loss can reduce the risk of developing these diseases and can be achieved by means of surgery, pharmacotherapy and lifestyle interventions. Lifestyle interventions for prevention and treatment of obesity include diet, exercise and psychological interventions. All lifestyle interventions have a modest but significant effect on weight loss, but there is little evidence to indicate that any one intervention is more effective. There is evidence of an additive effect for adjunct therapy, and the combination of diet, exercise and behavioural interventions appears to be most effective for both the prevention and treatment of obesity. [source] International Diabetes Federation: a consensus on Type 2 diabetes preventionDIABETIC MEDICINE, Issue 5 2007K. G. M. M. Alberti Abstract Aims, Early intervention and avoidance or delay of progression to Type 2 diabetes is of enormous benefit to patients in terms of increasing life expectancy and quality of life, and potentially in economic terms for society and health-care payers. To address the growing impact of Type 2 diabetes the International Diabetes Federation (IDF) Taskforce on Prevention and Epidemiology convened a consensus workshop in 2006. The primary goal of the workshop and this document was the prevention of Type 2 diabetes in both the developed and developing world. A second aim was to reduce the risk of cardiovascular disease in people who are identified as being at a higher risk of Type 2 diabetes. The IDF plan for prevention of Type 2 diabetes is based on controlling modifiable risk factors and can be divided into two target groups: ,,People at high risk of developing Type 2 diabetes ,,The entire population. Conclusions, In planning national measures for the prevention of Type 2 diabetes, both groups should be targeted simultaneously with lifestyle modification the primary goal through a stepwise approach. In addition, it is important that all activities are tailored to the specific local situation. Further information on the prevention of diabetes can be found on the IDF website: http://www.idf.org/prevention. [source] Human papillomavirus prevalence and cytopathology correlation in young Ugandan women using a low-cost liquid-based pap preparationDIAGNOSTIC CYTOPATHOLOGY, Issue 8 2010Janis M. Taube M.D. Abstract Screening for HPV-driven cervical dysplasia and neoplasia is a significant public health concern in the developing world. The purpose of this study was to use a manual, low-cost liquid-based Pap preparation to determine HPV prevalence in HIV-positive and HIV-negative young women in Kampala, Uganda and to correlate cervical cytopathology with HPV-DNA genotype. About 196 post-partum women aged 18,30 years underwent rapid HIV testing and pelvic examination. Liquid-based cervical cytology samples were processed using a low-cost manual technique. A DNA collection device was used to collect specimens for HPV genotyping. HIV and HPV prevalence was 18 and 64%, respectively. Overall, 49% of women were infected with a high-risk HPV genotype. The most common high-risk HPV genotypes were 16 (8.2%), 33 (7.7%), 35 (6.6%), 45 (5.1%), and 58 (5.1%). The prevalence of HPV 18 was 3.6%. HIV-positive women had an HPV prevalence of 86% compared to 59% in HIV-negative women (P = 0.003). The prevalence of HPV 16/18 did not differ by HIV status. HIV-positive women were infected with a significantly greater number of HPV genotypes compared to HIV-negative women. By multivariate analysis, the main risk factor for HPV infection was coinfection with HIV. HIV-positive women were four times more likely to have abnormal cytology than HIV-negative women (43% vs. 11.6%, P < 0.001). These data highlight that HIV infection is a strong risk factor for HPV infection and resultant abnormal cervical cytology. Notably, the manual low-cost liquid-based Pap preparation is practical in this setting and offers an alternate method for local studies of HPV vaccine efficacy. Diagn. Cytopathol. 2010;38:555,563. 2009 Wiley-Liss, Inc. [source] Suicide bombings: process of care of mass casualties in the developing worldDISASTERS, Issue 4 2009Masood Umer In recent times Pakistan's biggest city, Karachi, has witnessed numerous terrorist attacks. The city does not have an emergency response system and only one of the three public sector hospitals has a trauma centre. We describe the pattern of injuries and management of two terror-related mass casualty incidents involving suicide bombers in a developing nation with limited resources. The first incident occurred in May 2002 with 36 casualties, of whom 13 (36%) died immediately and 11 (30.5%) died at the primary receiving hospitals. The second incident was targeted against the local population in May 2004. The blast resulted in 104 casualties, of which 14 (13.46%) died at the site. All patients had their initial assessment and treatment based on Advanced Trauma and Life Support principles and documented on a trauma form. [source] Mainstreaming Risk Reduction in Urban Planning and Housing: A Challenge for International Aid OrganisationsDISASTERS, Issue 2 2006Christine Wamsler Abstract The effects of ,natural' disasters in cities can be worse than in other environments, with poor and marginalised urban communities in the developing world being most at risk. To avoid post-disaster destruction and the forced eviction of these communities, proactive and preventive urban planning, including housing, is required. This paper examines current perceptions and practices within international aid organisations regarding the existing and potential roles of urban planning as a tool for reducing disaster risk. It reveals that urban planning confronts many of the generic challenges to mainstreaming risk reduction in development planning. However, it faces additional barriers. The main reasons for the identified lack of integration of urban planning and risk reduction are, first, the marginal position of both fields within international aid organisations, and second, an incompatibility between the respective professional disciplines. To achieve better integration, a conceptual shift from conventional to non-traditional urban planning is proposed. This paper suggests related operative measures and initiatives to achieve this change. [source] An evidence-based approach to planning tobacco interventions for Aboriginal peopleDRUG AND ALCOHOL REVIEW, Issue 1 2004ROWENA G. IVERS Abstract Systematic reviews have shown that interventions such as the delivery of cessation advice by heath professionals and the use of nicotine replacement therapy are effective at increasing cessation rates, however little is known about whether such interventions are appropriate and effective for and thus transferable to Aboriginal Australians. The aim of this paper was to assess whether evidence of effectiveness for brief interventions for cessation and nicotine patches from studies conducted in other populations was likely to be transferable to Aboriginal people in the NT. This paper involved assessment of systematic reviews of evidence for the use of brief interventions for smoking cessation and the use of nicotine replacement therapy, when planning two such interventions for delivery to Aboriginal people. Emerging themes are discussed. There were many factors which were likely to mean that these brief advice on cessation and the use of nicotine patches were likely to be less effective when implemented in Aboriginal communities. The planned interventions were delivered in primary care, and were of low intensity. Few studies included in systematic reviews were set in the developing world or in minority populations. Many features of the context for delivery, such as the normality of the use of tobacco among Aboriginal people, the low socio-economic status of this population and cultural issues, may have meant that these interventions were likely to be less effective when delivered in this setting. Further research is required to assess effectiveness of tobacco interventions in this population, as evidence from systematic reviews in other populations may not be directly transferable to Aboriginal people. [source] Foreign direct investment and the dark side of decentralizationECONOMIC POLICY, Issue 49 2007Sebastian G. Kessing SUMMARY Fiscal decentralization VERTICAL, HORIZONTAL, AND FDI Both in the developed and developing world, decentralization of fiscal policy is frequently argued to foster investment, because allowing investors to choose between competing locations should make it difficult for each jurisdiction to tax the investment's returns. We point out that this ,horizontal' dimension of decentralization cannot eliminate ex post incentives to tax investments once they are irreversibly located in a jurisdiction, and that the negative ex ante investment effects of such ,hold up' problems are actually stronger when decentralization inevitably leads to multiple levels of taxation power in each location. Empirically, we detect significant negative effects on FDI of the ,vertical' dimension of decentralization, measured by the number of government layers, in a data set containing many countries and many suitable control variables. Indicators of overall fiscal decentralization do not appear to affect the investment climate negatively per se, but our theoretical arguments and empirical results suggest that policymakers should consider very carefully the form and degree of government decentralization if they aim at improving the investment climate. , Sebastian G. Kessing, Kai A. Konrad and Christos Kotsogiannis [source] Ethical issues related to epilepsy care in the developing worldEPILEPSIA, Issue 5 2009Chong-Tin Tan Summary There are three major issues of ethical concern related to epilepsy care in the developing world. First, is it ethical for a developing country to channel its limited resources from direct epilepsy care to research? The main considerations in addressing this question are the particular research questions to be addressed and whether such research will bring direct benefits to the local community. Second, in a country with limited resources, when does ignoring the high treatment gap become an ethical issue? This question is of particular concern when the community has enough resources to afford treatment for its poor, yet is not providing such care because of gross wastage and misallocation of the national resources. Third, do countries with plentiful resources have an ethical responsibility to help relieve the high epilepsy treatment gap of poor countries? Indeed, we believe that reasonable health care is a basic human right, and that human rights transcend national boundaries. Although health care is usually the responsibility of the nation-state, many modern states in the developing world are arbitrary creations of colonization. There is often a long process from the establishment of a political-legal state to a mature functional nation. During the long process of nation building, help from neighboring countries is often required. [source] | ||||||||||||||||||||||||||||||||||||||||||||||||||||