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Developed Technologies (developed + technology)
Selected AbstractsThe fallacies of hope: will we discover new antibiotics to combat pathogenic bacteria in time?FEMS MICROBIOLOGY REVIEWS, Issue 6 2006Miguel Vicente Abstract While newly developed technologies have revolutionized the classical approaches to combating infectious diseases, the difficulties associated with developing novel antimicrobials mean that these technologies have not yet been used to introduce new compounds into the market. The new technologies, including genomics and structural biology, open up exciting possibilities for the discovery of antibiotics. However, a substantial effort to pursue research, and moreover to incorporate the results into the production chain, is required in order to bring new antimicrobials to the final user. In the current scenario of emerging diseases and the rapid spread of antibiotic resistance, an active policy to support these requirements is vital. Otherwise, many valuable programmes may never be fully developed for lack of "interest" and funds (private and public). Will we react in time to avoid potential disaster? [source] Catalytic selective oxidation faces the sustainability challenge: turning points, objectives reached, old approaches revisited and solutions still requiring further investigationJOURNAL OF CHEMICAL TECHNOLOGY & BIOTECHNOLOGY, Issue 9 2010Fabrizio Cavani Abstract This review documents some examples of recently developed technologies and new approaches currently being investigated in the field of catalytic selective oxidation, that may contribute to improving the sustainability of the chemical industry. Tools to reach this ambitious target include process integration, the development of new reactions for the valorization of renewables and new catalysts able to perform complex transformations in a single step. Copyright © 2010 Society of Chemical Industry [source] A technology valuation model to support technology transfer negotiationsR & D MANAGEMENT, Issue 2 2007Dong-Hyun Baek The development and commercialization of advanced technologies will depend increasingly on efficient technology transfer and technology trading systems. This requires the development of technology markets or exchanges and hence a reliable technology valuation methodology. This paper develops a methodology for an objective and impartial valuation of fully developed technologies. A web-based technology valuation system is developed with which interested users can make efficient and real-time evaluations of technologies. [source] Cell-free synthesis of functional proteins using transcription/translation machinery entrapped in silica sol,gel matrixBIOTECHNOLOGY & BIOENGINEERING, Issue 1 2009Kyeong-Ohn Kim Abstract Herewith we report the encapsulation of functional protein synthesis machinery in a silica sol,gel matrix. When the sol,gel reaction using alkoxysilane monomers was carried out in the presence of Escherichia coli cell extract, macromolecular protein synthesis machinery in the cell extract was successfully immobilized within a silica gel matrix, catalyzing the translation of co-immobilized DNA when supplied with small-molecular-weight substrates for protein synthesis. The efficiency of protein synthesis was affected by the pore size of the gel structure, which was controlled through the use of appropriate additives during the sol,gel reactions. To the best of our knowledge, this is the first report describing the reproduction of the entire set of complicated biological process within an inorganic gel matrix, and we expect that the developed technology will find many applications in numerous fields such as high-throughput gene expression and the development of multifunctional biosensors. Biotechnol. Bioeng. 2009;102: 303,307. © 2008 Wiley Periodicals, Inc. [source] | ||||||||||