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Developed Nations (developed + nation)
Selected AbstractsHealth Care Reform: What the United States Can Learn from the Experience of Other Developed NationsHEALTH SERVICES RESEARCH, Issue 2 2010The panel discussion took place on June , at the AcademyHealth Annual Research Meeting in Washington First page of article [source] Targeting Alzheimer's disease: Is there a light at the end of the tunnel?DRUG DEVELOPMENT RESEARCH, Issue 2 2002David Gurwitz Abstract The prevalence of Alzheimer's disease (AD) is on the rise in developed nations as a consequence of longer human lifespan. Current costs to society are alarming, and are projected to become even more demanding on future health budgets. Considering the relative success of Parkinson's disease pharmacotherapy, the success of AD therapy has been disappointing. Quite a few novel and promising AD drug targets are presented in this special issue of Drug Development Research. These are built on countless research studies, by many bright minds, carried out over the last several decades. However, the answer to the growing AD threat must include reliable and accurate tools, presently lacking, for its early diagnosis in at-risk individuals. Drug Dev. Res. 56:45,48, 2002. © 2002 Wiley-Liss, Inc. [source] Amphetamine-induced movement disorderEMERGENCY MEDICINE AUSTRALASIA, Issue 3 2005Michael A Downes Abstract Recreational use of amphetamines is common in Australia and New Zealand when compared with other developed nations. The clinical effects are variable because of the potential of these drugs to increase the proportion of different biogenic amines in the central nervous system (CNS). The substances affected are adrenaline, noradrenaline, serotonin and dopamine. Movement disorders represent one of the less common presentations of amphetamine toxicity but one that health care workers should be aware of nonetheless. [source] The impact of (more) enlargement on the European Employment StrategyINDUSTRIAL RELATIONS JOURNAL, Issue 6 2005Mike Ingham ABSTRACT The European Union (EU) aspires to be the most competitive, full employment economy in the world and has set a number of ambitious targets to be met by 2010 in order that it can achieve this goal. At the same time, it is pursuing an enlargement policy that will witness the accession of an increasing number of less developed nations. This article explores some of the tensions that exist between these two goals as these are manifest in labour market indicators and finds the likelihood of meeting the deadline set for success remote. [source] Is Thabo Mbeki Africa's Saviour?INTERNATIONAL AFFAIRS, Issue 4 2003Gerrit Olivier Foreign relations are the main preoccupation of South African president, Thabo Mbeki. His role perception is dominated by a mission to improve the plight of Africa, and second to that, to act as the Third World's überdiplomat. Under his administration, South Africa's foreign policy has become almost an adjunct of his more holistic diplomatic pursuits. The New Partnership for Africa's Development (NEPAD) is the magnum opus of Mbeki's foreign policy, and the success or failure of this grand design for an African renaissance will determine his legacy and make or break his leadership in South Africa and in the rest of Africa. The success of his NEPAD diplomacy is a daunting task, requiring the support of his African peers, his South African constituency, and the leadership of the developed nations of the world. Dealing with these diverse elements, Mbeki's policy-making oscillates between realism and idealism, and between ideology and interests, giving the impression of a style of a prudent bureaucrat rather than that of a single-minded reformer. In the end, his diplomacy seems to founder because it fails to satisfy the contradictory demands of any of these three constituencies. However, even if NEPAD should fail as a project, its role could be that of a harbinger of a new political and economic era in Africa and the movement away from post-colonial orthodoxy. [source] Whither Latin America? trends and challenges of science in Latin AmericaIUBMB LIFE, Issue 4-5 2007Marcelo Hermes-Lima Abstract Science in Latin America has experienced vigorous growth in the past decade, as demonstrated by the fact that the Latin American share of the world's scientific publications increased from 1.8% in 1991 - 1995 to 3.4% in 1999 - 2003. Significant growth has also taken place in the numbers of PhDs in science and engineering (S&E) awarded in Latin American countries in recent years, including those in the natural sciences. Importantly, albeit at different rates, growth has been verified in almost all countries in the region, indicating a general effort to promote the development of S&E. In most research fields, however, the recognition or relative impact of Latin American science, as measured by the average number of citations received by published articles (CpP), is still below world averages and much lower than in developed nations. We show that average CpP values for a set of 34 representative developing and developed countries correlate significantly with gross expenditure in research and development (GERD), with gross domestic product (GDP) per capita and with the number of researchers per million inhabitants (RpM). Among those countries, Latin American nations present some of the lowest average values of CpP (<6), GERD (,1% of GDP) and RpM (<2,000). We also examined recent trends in scientific activity in Latin America, with focus on the natural sciences and on biochemistry and molecular biology (BMB). In terms of citation scores, publications in BMB compare favorably to those in other research fields within Latin America. At the same time, however, Latin American BMB is one of the areas for which relative impact - compared to developed nations or normalized to world averages - is lowest. These observations clearly indicate the need to establish effective policies to increase competitiveness in terms of the quality and international recognition of Latin American natural sciences in general, and BMB in particular, as opposed to merely increasing the absolute numbers of publications or the numbers of PhDs awarded in the region. IUBMB Life, 59: 199-210, 2007 [source] Our genes are not our destiny: incorporating molecular medicine into clinical practiceJOURNAL OF EVALUATION IN CLINICAL PRACTICE, Issue 1 2008Stephen J. Genuis MD FRCSC DABOG DABEM FAAEM Abstract In many developed nations, the state of publicly administered health care is increasingly precarious as a result of escalating numbers of chronically ill patients, inadequate medical personnel and hospital facilities, as well as sparse funding for ongoing upgrades to state-of-the-art diagnostic and therapeutic technology , an increased emphasis on aetiology-centred medicine should be considered in order to achieve improved health for patients and populations. Medical practice patterns which are designed to provide quick and effective amelioration of signs and symptoms are frequently not an enduring solution to many health afflictions and chronic disease states. Recent scientific discovery has rendered the drug-oriented algorithmic paradigm commonly found in contemporary evidence-based medicine to be a reductionist approach to clinical practice. Unfolding evidence appears to support a genetic predisposition model of health and illness rather than a fatalistic predestination construct , modifiable epigenetic and environmental factors have enormous potential to influence clinical outcomes. By understanding and applying fundamental clinical principles relating to the emerging fields of molecular medicine, nutrigenomics and human exposure assessment, doctors will be empowered to address causality of affliction when possible and achieve sustained reprieve for many suffering patients. [source] Globalization, coca-colonization and the chronic disease epidemic: can the Doomsday scenario be averted?JOURNAL OF INTERNAL MEDICINE, Issue 3 2000P. Zimmet Zimmet P (International Diabetes Institute, Melbourne, Australia). Globalization, coca-colonization and the chronic disease epidemic: can the Doomsday scenario be averted? J Intern Med 2000; 247: 301,310. There are at present approximately 110 million people with diabetes in the world but this number will reach over 220 million by the year 2010, the majority of them with type 2 diabetes. Thus there is an urgent need for strategies to prevent the emerging global epidemic of type 2 diabetes to be implemented. Tackling diabetes must be part of an integrated program that addresses lifestyle related disorders. The prevention and control of type 2 diabetes and the other major noncommunicable diseases (NCDs) can be cost- and health-effective through an integrated (i.e. horizontal) approach to noncommunicable diseases disease prevention and control. With the re-emergence of devastating communicable diseases including AIDS, the Ebola virus and tuberculosis, the pressure is on international and regional agencies to see that the noncommunicable disease epidemic is addressed. The international diabetes and public health communities need to adopt a more pragmatic view of the epidemic of type 2 diabetes and other noncommunicable diseases. The current situation is a symptom of globalization with respect to its social, cultural, economic and political significance. Type 2 diabetes will not be prevented by traditional medical approaches; what is required are major and dramatic changes in the socio-economic and cultural status of people in developing countries and the disadvantaged, minority groups in developed nations. The international diabetes and public health communities must lobby and mobilize politicians, other international agencies such as UNDP, UNICEF, and the World Bank as well as other international nongovernmental agencies dealing with the noncommunicable diseases to address the socio-economic, behavioural, nutritional and public health issues that have led to the type 2 diabetes and noncommunicable diseases epidemic. A multidisciplinary Task Force representing all parties which can contribute to a reversal of the underlying socio-economic causes of the problem is an urgent priority. [source] Nonmarital Fertility and the Effects of Divorce Rates on Youth Suicide RatesJOURNAL OF MARRIAGE AND FAMILY, Issue 4 2006Steven F. Messner Using pooled, time-series data for a sample of 15 developed nations, we assess the effect of divorce rates on gender-specific suicide rates for youths aged 15 , 19 with models of relative cohort size, lagged nonmarital fertility, and an interaction term for divorce rates and nonmarital fertility. The results reveal that, for young men, relative cohort size is positively related to suicide rates, and divorce rates interact with lagged nonmarital fertility. The interaction effect indicates that increases in divorces are especially consequential for suicide cohorts of male youths who were born in periods of high nonmarital fertility. For female youths, only divorce rates exert a significant effect on suicide rates, and it is a positive, main effect. [source] An international taxicab evaluation: comparing Tokyo with London, New York and ParisKNOWLEDGE AND PROCESS MANAGEMENT: THE JOURNAL OF CORPORATE TRANSFORMATION, Issue 2 2007Walter Skok An exploratory study was undertaken in order to evaluate the quality of Tokyo's taxicab industry, which provides a 24/7 door-to-door service for a daily average of 1.3 million people. This second paper, arising from the study, analyses the current situation in Tokyo, by using the Taxi Cab Management Model (TCMM) which identifies the key processes for managing and operating a taxicab service in any international city. The model provides a benchmark for measuring performance against other capital cities in developed nations. By comparing the results of this analysis with similar case studies of London, New York and Paris, areas of best practice are identified, as well as possible operational improvements. Copyright © 2007 John Wiley & Sons, Ltd. [source] Cover Picture , Mol.MOLECULAR NUTRITION & FOOD RESEARCH (FORMERLY NAHRUNG/FOOD), Issue 2 2009Nutr. Prostate cancer is the second most common cancer diagnosed in men and has increased dramatically in the past two decades partly as a result of lifestyle changes. Indeed, prostate cancer is a disease of the affluent West while Japan has one of the lowest rates of prostate cancer amongst economically developed nations. The traditional Japanese diet may reduce the risk of prostate cancer through a combination of increased soybean products and fish intake, with reduced red meat consumption. Also, the Mediterranean diet, as well as tomatoes and other red and orange coloured vegetables and fruits, may be protective against prostate cancer. While reading the special issue on "Diet and Prostate Cancer" we suggest you relax with a good cup of tea as tea may well play an important role in prostate cancer prevention. [source] Direct costs of managing Parkinson's disease in india: Concerns in a developing countryMOVEMENT DISORDERS, Issue 10 2006Mona Ragothaman MBBS Abstract Medicines and surgical interventions improve the quality of life of Parkinson's disease (PD) patients. These are still expensive options and are unaffordable to those living in developing countries. Managing PD in Indians who have a low annual gross national income (GNI; US$ 450,540) and for whom only a few (3%) have health insurance is a challenge. We interviewed 175 consecutive PD patients regarding health insurance and money spent for treatment. The annual income of nearly half the patients was less than rupees 50,000 (US$ 1,148.63). Patients in this study spend nearly 16% to 41.7% of the average Indian GNI to buy medicines. Costs of treating PD in India are lower than those in developed nations but are still out of reach for most Indian patients. © 2006 Movement Disorder Society [source] An evolutionary ecological perspective on demographic transitions: Modeling multiple currenciesAMERICAN JOURNAL OF HUMAN BIOLOGY, Issue 2 2002Bobbi S. Low Life history theory postulates tradeoffs of current versus future reproduction; today women face evolutionarily novel versions of these tradeoffs. Optimal age at first birth is the result of tradeoffs in fertility and mortality; ceteris paribus, early reproduction is advantageous. Yet modern women in developed nations experience relatively late first births; they appear to be trading off socioeconomic status and the paths to raised SES, education and work, against early fertility. Here, [1] using delineating parameter values drawn from data in the literature, we model these tradeoffs to determine how much socioeconomic advantage will compensate for delayed first births and lower lifetime fertility; and [2] we examine the effects of work and education on women's lifetime and age-specific fertility using data from seven cohorts in the Panel Study of Income Dynamics (PSID). Am. J. Hum. Biol. 14:149,167, 2002. © 2002 Wiley-Liss, Inc. [source] Pluralism, Public Choice, and the State in the Emerging Paradigm in Health SystemsTHE MILBANK QUARTERLY, Issue 1 2002Dov Chernichovsky The conceptualization of medicine as a unique field of endeavor is swiftly changing, and the change involves complex social and technological factors. The concept of "medicine" is dynamic: the range of ailments dealt with by medical care changes, as does the range of therapeutic options. In addition, with the growth in income and education, consumers,especially those in the middle- and upper-income brackets who are self-reliant and stress individualism,expect an increasing diversity of medical care and ins-titutions to supply it (Antonovsky 1987; Schneider, Dennerlein, Kose, et al. 1992; Williams and Calnan 1996). Hence, the character of the product or service offered and demanded is becoming more difficult to determine, especially in socioeconomically advanced communities. In developed nations, the absence of a correlation between a country's expenditures on medical care and the population's health as measured by morbidity and mortality complicates the issue further, since the association between health and the level of investment in medical care is not always as might be expected (OECD 1990). [source] Perceptual Diversity: Is Polyphasic Consciousness Necessary for Global Survival?ANTHROPOLOGY OF CONSCIOUSNESS, Issue 1 2001Tara W. Lumpkin Perceptual diversity allows human beings to access knowledge through a variety of perceptual processes, rather than merely through everyday waking reality. Many of these perceptual processes are transrational altered states of consciousness (meditation, trance, dreams, imagination) and are not considered valid processes for accessing knowledge by science (which is based primarily upon quantification, reductionism, and the experimental method). According to Erika Bourguignon's (1973) research in the 1970s, approximately 90 percent of cultures have institutionalized forms of altered states of consciousness, meaning that such types of consciousness are to be found in most human societies and are "normal." Now, however, transrational consciousness is being devalued in many societies as it is simultaneously being replaced by the monophasic consciousness of "developed" nations. Not only are we are losing (1) biodiversity (biocomplexity) in environments and (2) cultural diversity in societies, we also are losing (3) perceptual diversity in human cognitive processes. All three losses of diversity (bio, cultural, and cognitive) are interrelated. Cultures that value perceptual diversity are more adaptable than cultures that do not. Perceptually diverse cultures are better able to understand whole systems (because they use a variety of perceptual processes to understand systems) than are cultures that rely only on the scientific method, which dissects systems. They also are better stewards of their environments, because they grasp the value of the whole of biodiversity (biocomplexity) through transrational as well as scientific processes. Understanding through perceptual diversity leads to a higher degree of adaptability and evolutionary competence. From the perspective of an anthropologist who has worked with development organizations, development will continue to destroy perceptual diversity because it exports the dominant cognitive process of "developed" nations, i.e., monophasic consciousness. Destroying perceptual diversity, in turn, leads to the destruction of cultural diversity and biocomplexity. Drawing from research I conducted among traditional healers in Namibia, I conclude that development organizations need to listen to those who use transrational perceptual processes and also need to find a way to incorporate and validate perceptual diversity in their theoretical and applied frameworks. [source] Abortion and Neonaticide: Ethics, Practice and Policy in Four NationsBIOETHICS, Issue 3 2002Michael L. Gross Abortion, particularly late-term abortion, and neonaticide, selective non-treatment of newborns, are feasible management strategies for fetuses or newborns diagnosed with severe abnormalities. However, policy varies considerably among developed nations. This article examines abortion and neonatal policy in four nations: Israel, the US, the UK and Denmark. In Israel, late-term abortion is permitted while non-treatment of newborns is prohibited. In the US, on the other hand, late-term abortion is severely restricted, while treatment to newborns may be withdrawn. Policy in the UK and Denmark bridges some of these gaps with liberal abortion and neonatal policy. Disparate policy within and between nations creates practical and ethical difficulties. Practice diverges from policy as many practitioners find it difficult to adhere to official policy. Ethically, it is difficult to entirely justify perinatal policy in these nations. In each nation, there are elements of ethically sound policy, while other aspects cannot be defended. Ethical policy hinges on two underlying normative issues: the question of fetal/newborn status and the morality of killing and letting die. While each issue has been the subject of extensive debate, there are firm ethical norms that should serve as the basis for coherent and consistent perinatal policy. These include 1) a grant of full moral and legal status to the newborn but only partial moral and legal status to the late-term fetus 2) a general prohibition against feticide unless to save the life of the mother or prevent the birth of a fetus facing certain death or severe pain and suffering and 3) a general endorsement of neonaticide subject to a parent's assessment of the newborn's interest broadly defined to consider physical harm as well as social, psychological and or financial harm to related third parties. Policies in each of the nations surveyed diverging from these norms should be the subject of public discourse and, where possible, legislative reform. [source] Nitric oxide and vascular insulin resistanceBIOFACTORS, Issue 1 2009Guoyao Wu Abstract Obesity and type-II diabetes are growing major health issues worldwide. They are the leading risk factors for vascular insulin resistance, which plays an important role in the pathogenesis of cardiovascular disease, the leading cause of death in developed nations. Recent studies have shown that reduced synthesis of nitric oxide (NO; a major vasodilator) from L -arginine in endothelial cells is a major factor contributing to the impaired action of insulin in the vasculature of obese and diabetic subjects. The decreased NO generation results from a deficiency of (6R)-5,6,7,8-tetrahydrobiopterin [BH4; an essential cofactor for NO synthase (NOS)], as well as increased generation of glucosamine (an inhibitor of the pentose cycle for the production of NADPH, another cofactor for NOS) from glucose and L -glutamine. Accordingly, endothelial dysfunction can be prevented by (1) enhancement of BH4 synthesis through supplementation of its precursor (sepiapterin) via the salvage pathway; (2) transfer of the gene for GTP cyclohydrolase-I (the first and key regulatory enzyme for de novo synthesis of BH4); or (3) dietary supplementation of L -arginine (which stimulates GTP cyclohydrolase-I expression and inhibits hexosamine production). Modulation of the arginine,NO pathway by BH4 and arginine is beneficial for ameliorating vascular insulin resistance in obesity and diabetes. © 2009 International Union of Biochemistry and Molecular Biology, Inc. [source] First-year survival of infants born with congenital heart defects in Arkansas (1993-1998): A survival analysis using registry dataBIRTH DEFECTS RESEARCH, Issue 9 2003Mario A. Cleves BACKGROUND In the United States and other developed nations, birth defects are the leading cause of infant mortality. Congenital heart defects (CHDs) are among the most prevalent and fatal of all birth defects. Here we report the survival probability of infants born with CHDs in Arkansas and examine the impact of multiple malformations on survival. METHODS Birth and death certificate records were linked to birth defects registry data for infants born with CHDs from January 1993 through December 1998 in Arkansas. Both neonatal and first-year survival probabilities were estimated. These were computed non-parametrically using Kaplan-Meier's product limit method. A Cox proportional-hazards model was used to evaluate the relative importance of additional malformations on survival. RESULTS A total of 1,983 infants with CHDs were included in this study. The neonatal survival probability for this cohort was 94.0% (95% CI: 93.0%, 95.1%), and the first-year survival probability was 88.2% (95% CI: 86.8%, 89.6%). The presence of hypoplastic left heart syndrome conferred the greatest reduction in survival, whereas infants with pulmonic valve stenosis and infants with ventricular septal defects had the highest first-year survival. Infants with multiple CHDs had decreased survival compared to those with isolated heart defects. Survival was also adversely affected by the presence of congenital abnormalities in other body systems. CONCLUSIONS Neonatal and first-year survival of infants with CHDs varies by both the type of cardiac malformation and the presence of additional cardiac and non-cardiac malformations. Further work will focus on the effects of maternal and infant characteristics on survival. Birth Defects Research (Part A) 67:662,668, 2003. © 2003 Wiley-Liss, Inc. [source] | ||||||||||||||||||||||||||||