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Detection Capabilities (detection + capability)
Selected AbstractsImproving TCP performance over networks with wireless components using ,probing devices'INTERNATIONAL JOURNAL OF COMMUNICATION SYSTEMS, Issue 6 2002A. Lahanas Abstract TCP error control mechanism lacks the ability to detect with precision the nature of potential errors during communication. It is only capable of detecting the results of the errors, namely that segments are dropped. As a result, the protocol lacks the ability to implement an appropriate error recovery strategy cognizant of current network conditions and responsive to the distinctive error characteristics of the communication channel. TCP sender always calls for the sending window to shrink. We show that probing mechanisms could enhance the error detection capabilities of the protocol. TCP could then flexibly adjust its window in a manner that permits the available bandwidth to be exploited without violating the requirements of stability, efficiency and fairness that need to be guaranteed during congestion. Our experiments have three distinct goals: First, to demonstrate the potential contribution of probing mechanisms. A simple probing mechanism and an immediate recovery strategy are grafted into TCP-Tahoe and TCP-Reno. We show that, this way, standard TCP can improve its performance without requiring any further change. Second, to study the performance of adaptive strategies. An adaptive TCP with probing is used, that is responsive to the detected error conditions by alternating slow start, fast recovery and immediate recovery. An adaptive error recovery strategy can yield better performance. Third, to study the design limitations of the probing device itself. The aggressive or conservative nature of the probing mechanisms themselves can determine the aggressive or conservative behaviour of the protocol and exploit accordingly the energy/throughput trade-off. Copyright © 2002 John Wiley & Sons, Ltd. [source] Comparative morphology of stingray lateral line canal and electrosensory systemsJOURNAL OF MORPHOLOGY, Issue 11 2008Laura K. JordanArticle first published online: 24 JUL 200 Abstract Elasmobranchs (sharks, skates, and rays) possess a variety of sensory systems including the mechanosensory lateral line and electrosensory systems, which are particularly complex with high levels of interspecific variation in batoids (skates and rays). Rays have dorsoventrally compressed, laterally expanded bodies that prevent them from seeing their mouths and more often than not, their prey. This study uses quantitative image analysis techniques to identify, quantify, and compare structural differences that may have functional consequences in the detection capabilities of three Eastern Pacific stingray species. The benthic round stingray, Urobatis halleri, pelagic stingray, Pteroplatytrygon (Dasyatis) violacea, and benthopelagic bat ray, Myliobatis californica, show significant differences in sensory morphology. Ventral lateral line canals correlate with feeding ecology and differ primarily in the proportion of pored and nonpored canals and the degree of branching complexity. Urobatis halleri shows a high proportion of nonpored canals, while P. violacea has an intermediate proportion of pored and nonpored canals with almost no secondary branching of pored canals. In contrast, M. californica has extensive and highly branched pored ventral lateral line canals that extended laterally toward the wing tips on the anterior edge of the pectoral fins. Electrosensory morphology correlates with feeding habitat and prey mobility; benthic feeders U. halleri and M. californica, have greater electrosensory pore numbers and densities than P. violacea. The percentage of the wing surface covered by these sensory systems appears to be inversely related to swimming style. These methods can be applied to a broader range of species to enable further discussion of the relationship of phylogeny, ecology, and morphology, while the results provide testable predictions of detection capabilities. J. Morphol., 2008. © 2008 Wiley-Liss, Inc. [source] Performance characteristics according to Commission Decision 2002/657/EC in the fluorimetric determination of tetracycline in the absence and in the presence of magnesiumLUMINESCENCE: THE JOURNAL OF BIOLOGICAL AND CHEMICAL LUMINESCENCE, Issue 6 2007Noelia Rodríguez Abstract The fluorimetric determination of tetracycline is usually carried out in the presence of some metals that, through the formation of a complex with this antibiotic, enhance its fluorescence emission, giving more sensitive determination methods. It is well established that magnesium is one of these metals. However, it is possible that higher signals do not mean a real improvement in the quality of the analytical method. In this work, the univariate and multivariate fluorescence determination of tetracycline is performed in the presence and absence of Mg2+, comparing the quality of the analyses through some performance characteristics that, according to Commission Decision 2002/657/EC define the functional qualities of analytical methods. The methods with the best performance characteristics were multivariate determinations carried out in the absence of Mg2+, both when emission or excitation spectra were taken, the decision limits (CC,) being 13.1 and 20.1 µg/L and the detection capabilities (CC,) 25.3 and 38.5 µg/L, respectively. This study points out through a case study that higher analytical signals do not necessarily mean better performance characteristics of a method of analysis. Copyright © 2007 John Wiley & Sons, Ltd. [source] Protein EqualizerÔ Technology, : The quest for a "democratic proteome"PROTEINS: STRUCTURE, FUNCTION AND BIOINFORMATICS, Issue 14 2006Pier Giorgio Righetti Professor Abstract No proteome can be considered "democratic", but rather "oligarchic", since a few proteins dominate the landscape and often obliterate the signal of the rare ones. This is the reason why most scientists lament that, in proteome analysis, the same set of abundant proteins is seen again and again. A host of pre-fractionation techniques have been described, but all of them, one way or another, are besieged by problems, in that they are based on a "depletion principle", i.e. getting rid of the unwanted species. Yet "democracy" calls not for killing the enemy, but for giving "equal rights" to all people. One way to achieve that would be the use of "Protein Equalizer Technology" for reducing protein concentration differences. This comprises a diverse library of combinatorial ligands coupled to spherical porous beads. When these beads come into contact with complex proteomes (e.g. human urine and serum, egg white, and any cell lysate, for that matter) of widely differing protein composition and relative abundances, they are able to "equalize" the protein population, by sharply reducing the concentration of the most abundant components, while simultaneously enhancing the concentration of the most dilute species. It is felt that this novel method could offer a strong step forward in bringing the "unseen proteome" (due to either low abundance and/or presence of interference) within the detection capabilities of current proteomics detection methods. Examples are given of equalization of human urine and serum samples, resulting in the discovery of a host of proteins never reported before. Additionally, these beads can be used to remove host cell proteins from purified recombinant proteins or protein purified from natural sources that are intended for human consumption. These proteins typically reach purities of the order of 98%: higher purities often become prohibitively expensive. Yet, if incubated with "equalizer beads", these last impurities can be effectively removed at a small cost and with minute losses of the main, valuable product. [source] Enhancement of Anodic Response for DMSO at Ruthenium Oxide Film Electrodes as a Result of Doping with Iron(III)ELECTROANALYSIS, Issue 2 2003Brett Abstract The oxidation of dimethyl sulfoxide (DMSO) to dimethyl sulfone (DMSO2) is representative of numerous anodic oxygen-transfer reactions of organosulfur compounds that suffer from slow kinetics at noble metal electrodes. Anodic voltammetric data for DMSO are examined at various RuO2 -film electrodes prepared by thermal deposition on titanium substrates. The response for DMSO is slightly larger at RuO2 films prepared in a flame as compared with films prepared in a furnace; however, temperature is more easily controlled in the furnace. Doping of the RuO2 films with Fe(III) further improves the sensitivity of anodic response for DMSO. Optimal response is obtained at an Fe(III)-doped RuO2 -film electrode prepared using a deposition solution of 50,mM RuCl3 and 10,mM FeCl3 in a 1,:,1 mixture of isopropanol and 12,M HCl at an annealing temperature of 450,°C. The Levich plot (i vs. ,1/2) and Koutecky-Levich plot (1/i vs. 1/,1/2) of amperometric data for the oxidation of DMSO at an Fe(III)-doped RuO2 -film electrode configured as a rotated disk are consistent with an anodic response controlled by mass-transport processes at low rotational velocities. Flow injection data demonstrate that Fe(III)-doped RuO2 -film electrodes exhibit detection capability for methionine and cysteine in addition to DMSO. Detection limits for 100-,L injections of the three compounds are ca. 3.2×10,4,mM, i.e., ca. 32,pmol. [source] Quantum-Dot-Tagged Bioresponsive Hydrogel Suspension Array for Multiplex Label-Free DNA DetectionADVANCED FUNCTIONAL MATERIALS, Issue 6 2010Yuanjin Zhao Abstract A novel hydrogel suspension array, which possesses the joint advantages of quantum-dot-encoded technology, bioresponsive hydrogels, and photonic crystal sensors with full multiplexing label-free DNA detection capability is developed. The microcarriers of the suspension array are quantum-dot-tagged DNA-responsive hydrogel photonic beads. In the case of label-free DNA detection, specific hybridization of target DNA and the crosslinked single-stranded DNA in the hydrogel grid will cause hydrogel shrinking, which can be detected as a corresponding blue shift in the Bragg diffraction peak position of the beads that can be used for quantitatively estimating the amount of target DNA. The results of the label-free DNA detection show that the suspension array has high selectivity and sensitivity with a detection limit of 10,9,M. This method has the potential to provide low cost, miniaturization, and simple and real-time monitoring of hybridization reaction platforms for detecting genetic variations and sequencing genes. [source] Development and validation of an HPLC confirmatory method for the determination of seven tetracycline antibiotics residues in milk according to the European Union Decision 2002/657/ECJOURNAL OF SEPARATION SCIENCE, JSS, Issue 15 2007Victoria F. Samanidou Abstract An HPLC method with diode-array detection, at 355 nm, was developed and validated for the determination of seven tetracyclines (TCs) in milk: minocycline (MNC), TC, oxytetracycline (OTC), methacycline (MTC), demeclocycline (DMC), chlortetracycline (CTC), and doxycycline (DC). Oxalate buffer (pH 4) was used with 20% TCA as a deproteinization agent for the extraction of analytes from milk followed by SPE. The separation was achieved on an Inertsil ODS-3, 5 ,m, 250×4 mm2 analytical column at ambient temperature. The mobile phase, a mixture of A: 0.01 M oxalic acid and B: CH3CN, was delivered using a gradient program. The procedure was validated according to the European Union decision 2002/657/EC determining selectivity, stability, decision limit, detection capability, accuracy, and precision. Mean recoveries of TCs from spiked milk samples (50, 100, and 200 ng/g) were 93.8,100.9% for MNC, 96.8,103.7% for OTC, 96.3,101.8% for TC, 99.4,107.2% for DMC, 99.4,102.9% for CTC, 96.3,102.7% for MTC, and 94.6,102.1% for DC. All RSD values were lower than 8.5%. The decision limits CCa calculated by spiking 20 blank milk samples at MRL (100 ,g/kg) ranged from 101.25 to 105.84 ,g/kg, while detection capability CCbfrom 103.94 to 108.88 ,g/kg. [source] Mass spectrometry in bioinorganic analytical chemistryMASS SPECTROMETRY REVIEWS, Issue 2 2006Ryszard Abstract A considerable momentum has recently been gained by in vitro and in vivo studies of interactions of trace elements in biomolecules due to advances in inductively coupled plasma mass spectrometry (ICP MS) used as a detector in chromatography and capillary and planar electrophoresis. The multi-isotopic (including non-metals such as S, P, or Se) detection capability, high sensitivity, tolerance to matrix, and large linearity range regardless of the chemical environment of an analyte make ICP MS a valuable complementary technique to electrospray MS and MALDI MS. This review covers different facets of the recent progress in metal speciation in biochemistry, including probing in vitro interactions between metals and biomolecules, detection, determination, and structural characterization of heteroatom-containing molecules in biological tissues, and protein monitoring and quantification via a heteroelement (S, Se, or P) signal. The application areas include environmental chemistry, plant and animal biochemistry, nutrition, and medicine. © 2005 Wiley Periodicals, Inc. Mass Spec Rev 25:255,289, 2006 [source] | ||||||||||