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Depression-like Symptoms (depression-like + symptom)
Selected AbstractsFatigue and Relatedness Experiences of Inordinately Tired WomenJOURNAL OF NURSING SCHOLARSHIP, Issue 4 2000Laura Cox Dzurec Purpose: To examine the association of fatigue and interpersonal relatedness of fatigued women. Design: Hermeneutics. Methods: Seventeen fatigued American women, recruited through purposive sampling, were interviewed. Questions were based on data from previous research of women's fatigue and on characteristics of the theory of relatedness. Findings: Relatedness was significantly linked to fatigue. Participants moved toward disconnectedness, parallelism, comfortable noninvolvement, or through enmeshment and then toward parallelism. A spiral of intrapersonal and interpersonal changes, sense of emotional absence, lack of energy and motivation, and depression-like symptoms were reported by fatigued participants, particularly those whose state of relatedness shifted toward disconnectedness. Depression-like symptoms were associated with fatigue, but were differentiated from diagnosed depression. Participants noted that physical movement was helpful to them in mediating their fatigue. Conclusions: Findings from this study indicate the need for a database to describe the interplay among biological, psychosocial, and behavioral components of fatigue and to clarify its association with medical diagnoses, particularly depression. [source] Early manifestations of childhood depression: influences of infant temperament and parental depressive symptomsINFANT AND CHILD DEVELOPMENT, Issue 3 2008Maria A. Gartstein Abstract In this longitudinal study, 83 parents of infants between 3 and 12 months completed questionnaires assessing demographic information, infant temperament, and maternal depression. When these children were at least 18 months of age, parents completed follow-up questionnaires assessing toddler temperament and depression-like symptoms. We were primarily interested in the contributions of infant temperament and maternal depression to toddler depressive problems, and the analytic strategy involved controlling for toddler temperament in order to isolate the influence of infancy characteristics. The findings indicated that lower levels of infant regulatory capacity and greater severity of maternal depression were predictive of toddler depression-like symptoms. Moderator effects of infant temperament were also examined, with the negative affectivity * maternal depression interaction emerging as significant. Follow-up analyses indicated that the risk for early manifestations of depression was attenuated for children with lower negative affectivity in infancy and parents who reported lower levels of their own depressive symptoms; conversely, children exhibiting higher infant negative emotionality had higher levels of depression-like symptoms as toddlers, regardless of their parents' level of depression. The present findings further suggest that parental depressive symptoms need not be ,clinically significant' to predict toddler affective problems. Copyright © 2008 John Wiley & Sons, Ltd. [source] Fatigue and Relatedness Experiences of Inordinately Tired WomenJOURNAL OF NURSING SCHOLARSHIP, Issue 4 2000Laura Cox Dzurec Purpose: To examine the association of fatigue and interpersonal relatedness of fatigued women. Design: Hermeneutics. Methods: Seventeen fatigued American women, recruited through purposive sampling, were interviewed. Questions were based on data from previous research of women's fatigue and on characteristics of the theory of relatedness. Findings: Relatedness was significantly linked to fatigue. Participants moved toward disconnectedness, parallelism, comfortable noninvolvement, or through enmeshment and then toward parallelism. A spiral of intrapersonal and interpersonal changes, sense of emotional absence, lack of energy and motivation, and depression-like symptoms were reported by fatigued participants, particularly those whose state of relatedness shifted toward disconnectedness. Depression-like symptoms were associated with fatigue, but were differentiated from diagnosed depression. Participants noted that physical movement was helpful to them in mediating their fatigue. Conclusions: Findings from this study indicate the need for a database to describe the interplay among biological, psychosocial, and behavioral components of fatigue and to clarify its association with medical diagnoses, particularly depression. [source] Nelumbinis Semen reverses a decrease in hippocampal 5-HT release induced by chronic mild stress in ratsJOURNAL OF PHARMACY AND PHARMACOLOGY: AN INTERNATI ONAL JOURNAL OF PHARMACEUTICAL SCIENCE, Issue 5 2005Moonkyu Kang Depression is associated with a dysfunctional serotonin system. Recently, several lines of evidence have suggested that a very important evoking factor in depression may be a serotonin deficit in the hippocampus. This study assessed the antidepression effects of Nelumbinis Semen (NS) through increasing serotonin concentrations under normal conditions and reversing a decrease in serotonin concentrations in rat hippocampus with depression-like symptoms induced by chronic mild stress (CMS). Using an in-vivo microdialysis technique, the serotonin-enhancing effect of NS on rat hippocampus was investigated and its effects compared with those of two well-known antidepressants, Hypericum perforatum (St John's wort) and fluoxetine (Prozac). Rats were divided into five groups: saline-treated normal, without CMS; saline-treated stress control; NS-, St John's wort- and fluoxetine-treated rats under CMS for 8 weeks or no stress treatment. NS and fluoxetine significantly increased serotonin in normal conditions and reversed a CMS-induced decrease in serotonin release in the hippocampus (P< 0.05 compared with normal group or control group under CMS). These results suggest that NS increases the serotonin levels normally decreased in depression, resulting in an enhancement of central serotonergic transmission and possible therapeutic action in depression. It is suggested that NS may present an antidepressant effect through enhancement of serotonin. [source] | ||||||||||