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Cyclodextrin
Kinds of Cyclodextrin Terms modified by Cyclodextrin Selected AbstractsCyclodextrin-based nonaqueous electrokinetic chromatography with UV and mass spectrometric detection: Application to the impurity profiling of amiodarone,ELECTROPHORESIS, Issue 17 2008Roelof Mol Abstract The potential of nonaqueous electrokinetic chromatography (NAEKC) using cyclodextrins (CD) for the analysis of basic drugs and related compounds was evaluated. Both UV absorbance and mass spectrometric (MS) detection were employed. Addition of neutral CD to the NA background electrolyte did not significantly enhance the separation of a test mixture of basic drugs, and no change in selectivity was observed. In contrast, anionic single-isomer-sulfated CD strongly added to the selectivity of the NAEKC system inducing an improved resolution among the test compounds and increasing the migration time window. The applicability of the NAEKC system using anionic CD is demonstrated by the profiling of a sample of the drug amiodarone that had been stored for 1,year at room temperature. Amiodarone is poorly soluble in water. NAEKC-UV analysis indicated the presence of at least seven impurities in the amiodarone sample. In order to identify these compounds, the NAEKC system was coupled directly to electrospray ionization (ESI) ion-trap MS. The total of detected impurities increased to 12 due to the added sensitivity and selectivity of MS detection. Based on the acquired MS/MS data, three sample constituents could be identified as ,known' impurities (British Pharmacopoeia), whereas for three unknown impurities molecular structures could be proposed. Estimated limits of detection for amiodarone using the NAEKC method were 1,,g/mL with UV detection and 15,ng/mL with ESI-MS detection (full-scan). Based on relative responses, the impurity content of the stored drug substance was estimated to be 0.33 and 0.47% using NAEKC-UV and NAEKC-ESI-MS, respectively. [source] ,-Cyclodextrin as novel chiral probe for enantiomeric separation by electromigration methodsELECTROPHORESIS, Issue 21 2006Dorothee Wistuba Abstract Native ,-CD has been employed as chiral selector in CE and MEKC. To investigate the potential of the enantiodiscriminating properties of ,-CD, negatively charged 5-dimethylamino-1-naphthalene-sulfonyl (dansyl)-, 2,4-dinitrophenyl (DNP)- and FMOC-derivatives of several amino acids, 1,1'-binaphthyl-2,2'-diylhydrogenphosphate, flavanones and three positively charged drugs have been selected as testing samples. Enantioresolution factors up to 4.82 have been observed. The results were compared with those achieved by the conventional running buffer additives ,-, ,- and ,-CDs. For several examples a steady increase of enantioresolution with increasing degree of oligomerization has been detected. [source] Structural Studies of ,-Cyclodextrin and Permethylated ,-Cyclodextrin Inclusion Compounds of Cyclopentadienyl Metal Carbonyl ComplexesEUROPEAN JOURNAL OF INORGANIC CHEMISTRY, Issue 8 2006Susana S. Braga Abstract [CpM(CO)nCl] complexes with M = Fe (n = 2) and Mo (n = 3) have been immobilised in plain ,-cyclodextrin (,-CD) and permethylated ,-CD (TRIMEB) by methods tailored according to the stabilities and solubilities of the individual components. Four adducts were obtained with a 1:1 host/guest stoichiometry. The compounds were studied by powder X-ray diffraction (XRD), thermogravimetric analysis (TGA), 13C{1H} CP/MAS NMR and FTIR spectroscopy. A comparison of the experimental powder XRD data for the TRIMEB/[CpMo(CO)3Cl] inclusion compound with reference patterns revealed that the crystal packing is very similar to that reported previously for a TRIMEB/ethyl laurate inclusion compound. The unit-cell parameters refined to a = 14.731, b = 22.476, c = 27.714 Å (volume = 9176.3 Å3), and the space group was confirmed as P212121. A hypothetical structural model of the inclusion compound was subsequently obtained by global optimisation using simulated annealing. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006) [source] Diisobutylaluminium Hydride (DIBAL-H) Promoted Secondary Rim Regioselective Demethylations of Permethylated ,-Cyclodextrin: A Mechanistic ProposalEUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 8 2010Sulong Xiao Abstract Diisobutylaluminium hydride (DIBAL-H) promotes secondary rim regioselective bis-de- O -methylation at the 2A - and 3B -positions of permethylated ,-cyclodextrin. This result contrasts with the selective bis-de- O -benzylation of perbenzylated cyclodextrins in which regioselective deprotection occurs at the primary rim. To gain an insight into the mechanism of this remarkable contrasting behavior, the two corresponding permethylated cyclodextrins with an alcohol function at either the 2- or 3-position were synthesized. The cyclodextrin with the alcohol at the 3-position reacts withDIBAL-H to afford the 2A,3B -diol whereas the cyclodextrin with the alcohol at the 2-position is unreactive. This observation allows us to propose a mechanism for the demethylation reaction that involves for each demethylation step two molecules of aluminium reagent, in accord with the previous hypothesis on the debenzylation reaction. The second demethylation step appears to be faster than the first, the coordination of aluminium now being an intramolecular process. [source] Multicomponent Approach Towards the Synthesis of Substituted Pyrroles under Supramolecular Catalysis Using , -Cyclodextrin as a Catalyst in Water Under Neutral ConditionsHELVETICA CHIMICA ACTA, Issue 10 2009Narayana Murthy, Sabbavarapu Abstract Synthesis of substituted pyrroles in H2O by using , -cyclodextrin as a supramolecular catalyst is described. This reaction has several advantages over existing methods and provides substituted pyrroles in good-to-excellent yields (79,89%). The supramolecular catalysis of the reaction was studied using 1H-NMR spectroscopy. , -Cyclodextrin can be recovered and reused several times without loss of activity. [source] , -Cyclodextrin as Inhibitor of the Precipitation Reaction between Berberine and Glycyrrhizin in Decoctions of Natural Medicines: Interaction Studies of Cyclodextrins with Glycyrrhizin and Glycyrrhetic Acid by 1H-NMR Spectroscopy and Molecular-Dynamics CalculationHELVETICA CHIMICA ACTA, Issue 9 2008Miyoko Kamigauchi Abstract To prevent the precipitation reaction between glycyrrhizin (1) and berberine (3) in the decoctions of Glycyrrhiza/Coptis rhizome or Glycyrrhiza/Phellodendron bark, the presence of cyclodextrin (CD) in the mixture was proven to be effective. The preventing effect decreased in the order , -CD>, -CD, and no effect was observed for , -CD. On the other hand, the extraction degree of 1 from the natural medicine Glycyrrhia was considerably increased in the presence of , -CD, , -CD being much more effective than , - or , -CD. Thus, the blocking effect of CD on the precipitate formation between 1 and 3 is suggested to be primarily dependent on the stability of the inclusion complex of the CD with 1. To establish the structure of such a preferred inclusion complex, the interactions of 1 with , - and , -CDs were investigated by 1H-NMR spectroscopy and molecular-dynamics (MD) calculations. The 1H-NMR measurements showed that the increase in solubility of 1 in H2O is dependent on the degree of its inclusion into the CD, which depends on the molecular size of the CD. The MD calculations suggested that the H-bond interactions are sufficiently strong to form a stable [1/, -CD] complex, in which the lipophilic rings C, D, and E of 1 are fully inserted into the molecular cavity of , -CD, thus forming a kind of structure covered by a hydrophilic molecular capsule, while such an interaction mode is impossible for , - or , -CD. [source] Direct Spectroscopic Evidence that the Photochemical Outcome of Flutamide in a Protein Environment is Tuned by Modification of the Molecular Geometry: A Comparison with the Photobehavior in Cyclodextrin and VesiclesHELVETICA CHIMICA ACTA, Issue 2 2003Salvatore Sortino The photoreactivity of the phototoxic anticancer drug flutamide (FM) in the presence of bovine serum albumin (BSA) has been investigated. The presence of BSA induces a remarkable modification of the photochemical outcome of the drug with respect to that observed in aqueous solution. Induced circular dichroism (ICD) measurements combined with theoretical calculations provide strong evidence that the new photochemical scenario is tuned by changes of the molecular geometry of FM when incorporated in the protein microenvironment. This behavior presents close analogies to that found in the presence of either cyclodextrin or phospholipid vesicles, chosen as models for biological systems, and delineates a quite general photochemical picture that can be useful for a more appropriate understanding of the adverse phototoxic effects induced by this drug. [source] Synthesis of Half-Channels by the Anionic Polymerization of Ethylene Oxide Initiated by Modified CyclodextrinADVANCED MATERIALS, Issue 40 2009Nezha Badi Amphiphilic star-shaped oligomers are produced by anionic polymerization of ethylene oxide (EO) using per-2,3-di- O -heptyl- , -(or ,)cyclodextrins as initiators , a versatile way of synthesizing artificial channels bearing one polyEO branch per glucose unit. The behavior of the amphiphilic molecules in lipid membranes is studied by electrical measurements, which confirms the formation of transient, well-defined dimeric ionic channels (see figure). [source] Ditopic Cyclodextrin-Based Receptors: New Perspectives in Aqueous Organometallic CatalysisADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 9 2010Natacha Six Abstract The mass transfer properties of mono- and ditopic ,-cyclodextrin-based receptors have been evaluated in a biphasic palladium-catalyzed Tsuji,Trost reaction and compared to one of the best mass-transfer promoters, namely the randomly methylated ,-cyclodextrin. While monotopic receptors appeared to be poor mass-transfer promoters of long alkyl chain allyl carbonates or urethanes, cooperative effects have been evidenced with ditopic cyclodextrin-based receptors, opening new perspectives in aqueous organometallic catalysis. [source] Preparation and sorption studies of ,-cyclodextrin/epichlorohydrin copolymersJOURNAL OF APPLIED POLYMER SCIENCE, Issue 5 2010Dawn Y. Pratt Abstract ,-Cyclodextrin (,-CD) copolymer materials were synthesized by reacting different mole ratios (1 : 15, 1 : 25 and 1 : 35) of ,-CD with epichlorohydrin (EP). The products were characterized using N2 porosimetry, Fourier Transform Infrared spectroscopy, 13C CP-MAS NMR spectroscopy, thermogravimetry analysis, elemental (C and H) analysis, and scanning electron microscopy. The sorption properties in aqueous solution were studied using p-nitrophenol (PNP) with UV,Vis spectrophotometry. Sorption isotherms were obtained at pH 4.6 and three temperatures (22, 35, and 45°C) and at pH 10.3 at 22°C. The isotherms were analyzed using the BET isotherm model and the sorption parameters provided estimates of the surface area, sorption capacity, and isosteric heats of sorption for each polymeric material. The estimated surface areas are as follows: 58.2, 52.1, and 90.1 m2/g at pH 4.6. At pH 10.3, the estimated surface areas are 44.2, 40.5, and 58.5 m2/g, respectively. The removal efficiency of PNP by the polymeric materials ranged between 4.5 and 58% for the conditions investigated whereas the isosteric heats ranged between ,24.5 and ,13.6 kJ/mol. Removal efficiencies were concluded to strongly depend on the sorption conditions such as pH, temperature, and the relative amounts of sorbent and dye in aqueous solution. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010 [source] ,-cyclodextrin reduces bioavailability of orally administered [3H]benzo[a]pyrene in the ratJOURNAL OF PHARMACEUTICAL SCIENCES, Issue 1 2005Goran Westerberg Abstract The excretion and plasma kinetics of total radioactivity were studied following single oral administration of [3H]benzo[a]pyrene after multiple oral administration of ,-cyclodextrin at 0, 5, 50, or 500 mg/kg/day. The AUC and Cmax values in male and female rats following administration of [3H]benzo[a]pyrene in combination with 5 to 500 mg/kg ,-cyclodextrin were considerably lower than that in rats administered [3H]benzo[a]pyrene alone. At all dose levels of ,-cyclodextrin, the excretion of total radioactivity was almost entirely via feces, with <2% recovered in urine, demonstrating either that absorption of the orally administered dose was low or that, for any absorbed material, biliary excretion was the main route of excretion. However, following administration of vehicle, up to 5% of the administered radioactivity was recovered in the urine, suggesting that absorption may have been reduced by the presence of ,-cyclodextrin in the intestine. At all dose levels of ,-cyclodextrin, there was minimal retention of radioactivity in the carcase at the end of the collection period. ,-Cyclodextrin did not affect the apparent terminal half-life of radioactivity. Therefore, the reduced systemic exposure of rats to radioactivity in the presence of ,-cyclodextrin is likely related to a reduced oral bioavailability. © 2004 Wiley-Liss, Inc. and the American Pharmacists Association J Pharm Sci 94:114,119, 2005 [source] Improvement of Subcutaneous Bioavailability of Insulin by Sulphobutyl Ether ,-Cyclodextrin in RatsJOURNAL OF PHARMACY AND PHARMACOLOGY: AN INTERNATI ONAL JOURNAL OF PHARMACEUTICAL SCIENCE, Issue 8 2000KEIICHI TOKIHIRO The objective of this study was to examine and compare how hydrophilic ,-cyclodextrin derivatives (,-CyDs) improve the bioavailability of insulin following subcutaneous injection of insulin solution in rats. When insulin solutions in the absence of ,-CyDs were injected into the dorsal subcutaneous tissues of rats, the absolute bioavailability of insulin calculated from plasma immunoreactive insulin (IRI) levels was approximately 50%. When maltosyl-,-cyclodextrin was added to the solutions, there was no change in the plasma IRI levels and hypoglycaemia compared with those of the insulin-alone solution. Dimethyl-,-cyclodextrin decreased the bioavailability of insulin, although it increased the maximal concentration of IRI in plasma and the capillary permeability of the fluorescein isothiocyanatedextran 40, a non-degraded permeation marker. When insulin solutions containing sulphobutyl ether-,-cyclodextrin with a degree of substitution of the sulphobutyl group of 3,9 (SBE4-,-CyD) were injected, the IRI level rapidly increased and maintained higher IRI levels for at least 8h. The bioavailability of the insulin/SBE4-,-CyD system was about twice that of insulin alone and approached 96%. The enhancing effects of SBE4-,-CyD may be in part due to the inhibitory effects of SBE4-,-CyDs on the enzymatic degradation and/or the adsorption of insulin onto the subcutaneous tissue at the injection site, although this does not apparently facilitate capillary permeability. These results suggest that SBE4-,-CyD in aqueous insulin injection for subcutaneous administration is useful for improving the bioavailability and the hence the pharmacological effects of insulin. [source] Multi-Responsive Supramolecular Double Hydrophilic Diblock Copolymer Driven by Host-Guest Inclusion Complexation between , -Cyclodextrin and Adamantyl MoietiesMACROMOLECULAR CHEMISTRY AND PHYSICS, Issue 24 2009Hao Liu Abstract Well-defined , -CD-terminated poly(N -isopropylacrylamide) (, - CD -PNIPAM) was synthesized via a combination of atom transfer radical polymerization (ATRP) and click chemistry. Moreover, adamantyl-terminated poly(2-(diethylamino)ethyl methacrylate) (Ad -PDEA) was synthesized by ATRP using an adamantane-containing initiator. Host-guest inclusion complexation between ,-CD and adamantyl moieties drives the formation of supramolecular double hydrophilic block copolymers (DHBC) from , -CD-PNIPAM and Ad -PDEA. The obtained supramolecular PNIPAM- b -PDEA diblock copolymer exhibits intriguing multi-responsive and reversible micelle-to-vesicle transition behavior in aqueous solution by dually playing with solution pH and temperatures. [source] Copolymerization of Fluorinated Monomers with Hydrophilic Monomers in Aqueous Solution in Presence of CyclodextrinMACROMOLECULAR CHEMISTRY AND PHYSICS, Issue 11 2006Oliver Kretschmann Abstract Summary: New fluorinated copolymers were synthesized by copolymerization of 1H,1H,2H,2H- perfluorodecyl methacrylate (1) with hydrophilic comonomers methacrylic acid (3), 2-acrylamido-2-methylpropane sulfonic acid (6), 3-trimethylammonium propyl methacrylamide chloride (7) and N,N -dimethylmethacrylamidopropyl- N -3-sulfopropylammoniumbetaine (8). The reaction was carried out in water using randomly methylated , -cyclodextrin (RAMEB) for solubilization of the fluorinated monomer by forming a host-guest complex (1a). Polymerization kinetics were investigated and copolymerization parameters were determined. Additionally, a RAMEB complex of tert -butyl methacrylate (2a) was copolymerized with 1a in water. For comparison, copolymerization of the uncomplexed monomers 1 and 2 were carried out in organic solvents. Evaluation of copolymerization kinetics and parameters showed significant differences in the relative reactivities of the free monomers and the monomer-RAMEB complexes. [source] Gel-to-Sol and Sol-to-Gel Transitions Utilizing the Interaction of , -Cyclodextrin with Dodecyl Side Chains Attached to a Poly(acrylic acid) BackboneMACROMOLECULAR RAPID COMMUNICATIONS, Issue 10 2005Itsuro Tomatsu Abstract Summary: By utilizing the interaction of , -cyclodextrin (, -CD) with dodecyl side chains in polymers of x mol-% dodecyl-modified poly(acrylic acid) (p(AA/C12(x))), systems that undergo gel-to-sol and sol-to-gel transitions were successfully constructed. Rheological experiments indicated that addition of , -CD to the hydrogel of p(AA/C12(5)) caused a drastic decrease in the viscosity, while addition of oligo(, -CD) to the solution of p(AA/C12(2)) led to a remarkable increase in the viscosity. Photographs for a gel-to-sol transition upon addition of , -CD to 5.0 g,·,L,1 p(AA/C12(5)). [source] Supramolecular Assembly of Gold Nanoparticles Mediated by Polypseudorotaxane with Thiolated , -Cyclodextrin,MACROMOLECULAR RAPID COMMUNICATIONS, Issue 5 2005Yu Liu Abstract Summary: A water-soluble gold nanoparticle aggregate 2 was prepared by chloroauric acid and a polypseudorotaxane 1 of mono-6-thio- , -cyclodextrin with poly(propylene glycol) bis(2-aminopropyl ether) (,,,2,000) in the presence of sodium borohydride in N,N -dimethylformamide (DMF) solution. The investigative results indicated that the gold nanoparticle aggregate 2 might act as an efficient DNA-cleavage reagent. A typical TEM image of gold nanoparticle aggregate 2. [source] Gelation Rate Modulation of an , -Cyclodextrin and Poly(ethylene glycol)-Grafted Hyaluronic Acid Solution System by Inclusion Complexation of a Microphase-Separated StructureMACROMOLECULAR RAPID COMMUNICATIONS, Issue 6 2004Tsuyoshi Nakama Abstract Summary: The gelation rate of a poly(ethylene glycol)-grafted hyaluronic acid (PEG- graft -HA) solution with adding , -CD was investigated in term of the microphase separation between the grafted PEG and HA. The gelation rate of PEG- graft -HA exhibiting the microphase-separated structure was two times higher than that of PEG- graft -HA showing a homogeneous miscible state. The formation of microphases by PEG- graft -HA contributes to its rapid gelation upon the addition of , -CDs. [source] Nachweis von RNA-Interferenz im Menschen nach systemischer Gabe von siRNAsANGEWANDTE CHEMIE, Issue 36 2010Jens Kurreck Prof. In die Entwicklung neuer Therapeutika unter Einsatz der RNA-Interferenz werden große Hoffnungen gesetzt. Kürzlich gelang es, kurze interferierende RNAs (siRNAs) mithilfe zielgerichteter Nanopartikel, die aus einem Cyclodextrin- Polymer, Adamantan-gekuppeltem Polyethylenglycol und Transferrin bestanden (siehe Bild), in Tumorzellen von Melanom-Patienten zu transportieren und nachzuweisen, dass die Ziel-mRNA spezifisch über den RNA-Interferenz-Mechanismus abgebaut wird. [source] Lichtgesteuerte molekulare Erkennung und Adhäsion von Vesikeln,ANGEWANDTE CHEMIE, Issue 31 2010Krishna, Mohan Nalluri Supramolekularer Kleber: Die photoinduzierte Isomerisierung von difunktionellen Azobenzolen wird verwendet, um die molekulare Erkennung und Adhäsion von Cyclodextrin(CD)-Vesikeln herbeizuführen und aufzulösen. Die Wirkung dieses lichtreaktiven supramolekularen Klebers beruht auf der cis-trans -Isomerisierung der Azogruppen (siehe Bild; schwarze Kugeln CD, grün trans, rot cis). [source] Photoresponsive Pseudopolyrotaxane Hydrogels Based on Competition of Host,Guest Interactions,ANGEWANDTE CHEMIE, Issue 26 2010Xiaojuan Liao Kontrollierter Auf- und Abbau: Ein ternäres Hydrogel bestehend aus Polyethylenglycol (PEG), ,-Cyclodextrin(,-CD)-Pseudopolyrotaxan (PPR) und einem photoresponsiven Azobenzol wird durch abwechselnde Bestrahlung mit UV- und sichtbarem Licht reversibel aggregiert und gelöst. Grundlage dieses Prozesses ist die Konkurrenz zwischen der Azobenzol- und der PEG-Komponente um die Komplexierung mit ,-CD-PPR. [source] Der Einsatz von Relaxationserhöhungen in einer paramagnetischen Umgebung zur Proteinstrukturbestimmung mit NMR-Spektroskopie,ANGEWANDTE CHEMIE, Issue 44 2009Tobias Madl Dr. Ein Mehr an Informationen: Relaxationserhöhungen durch eine inerte paramagnetische Umgebung (PREs) wurden zusammen mit einem eingegrenzten NOE-Datensatz in einem modellfreien Strukturbestimmungsverfahren genutzt. Strukturen für zwei Proteine , Ubiquitin (8,kDa) und das Maltose-bindende Protein (42,kDa; im Komplex mit ,-Cyclodextrin) , wurden mithilfe von PREs und NOEs zwischen austauschenden Protonen ermittelt. [source] An Efficient Dye-Sensitized Solar Cell with an Organic Sensitizer Encapsulated in a Cyclodextrin Cavity,ANGEWANDTE CHEMIE, Issue 32 2009Hyunbong Choi Wird der Farbstoff JK-2 in einem Cyclodextrin (CD) eingeschlossen, so ist die Ladungsrekombination verzögert und die Aggregation verhindert (siehe Bild). Eine Solarzelle mit einem solchen ,-CD/JK-2-System und einem Polymergel als Elektrolyt ergab bei ausgezeichneter Stabilität eine Gesamtumwandlungseffizienz von 7.40,%; dies ist der bislang höchste Wert für farbstoffsensibilisierte Solarzellen mit organischen Sensibilisatoren. [source] ChemInform Abstract: Facile and Efficient Synthesis of 3,4,5-Substituted Furan-2(5H)-ones by Using ,-Cyclodextrin as Reusable Catalyst.CHEMINFORM, Issue 45 2009S. Narayana Murthy Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Simple, One-Pot Procedure for the Generation of Homoallylic Alcohols from Barbier-Type Allylation of Gem-Diacetates in the Presence of ,-Cyclodextrin in Water.CHEMINFORM, Issue 45 2007M. Somi Reddy Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] The Effect of ,-Cyclodextrin on the Diastereoselective NaBH4 Reduction of Cyclohexanone Derivatives.CHEMINFORM, Issue 52 2006Myung Soo Seo Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Controllable Oxidation of Sulfides to Sulfoxides and Sulfones with Aqueous Hydrogen Peroxide in the Presence of ,-Cyclodextrin.CHEMINFORM, Issue 50 2006Hong-Bing Ji Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Conversion of Epoxides to ,-Chlorohydrins with Thionyl Chloride and ,-Cyclodextrin in Water.CHEMINFORM, Issue 52 2005K. Surendra Abstract For Abstract see ChemInform Abstract in Full Text. [source] Aqueous Phase Synthesis of Thiazoles and Aminothiazoles in the Presence of ,-Cyclodextrin.CHEMINFORM, Issue 51 2005M. Narender Abstract For Abstract see ChemInform Abstract in Full Text. [source] A Mild and Efficient Synthesis of ,-Tosylamino Ketones from Aryl Aziridines in the Presence of ,-Cyclodextrin and NBS in Water.CHEMINFORM, Issue 23 2005M. Somi Reddy Abstract For Abstract see ChemInform Abstract in Full Text. [source] A Simple and Highly Selective Biomimetic Oxidation of Alcohols and Epoxides with N-Bromosuccinimide in the Presence of ,-Cyclodextrin in Water.CHEMINFORM, Issue 30 2004N. Srilakshmi Krishnaveni No abstract is available for this article. [source] | ||||||||||||||||||||||||||||||||||||||||