			Home About us Contact

Cycloaddition Approach (cycloaddition + approach)

Distribution by Scientific Domains

Chemistry	100%

Selected Abstracts

A Tandem, Nitroalkene Conjugate Addition/[3+2] Cycloaddition Approach to the Synthesis of the Pentacyclic Core of (±)-Scandine

ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 16-17 2006
Scott
Abstract The complete pentacyclic core of the melodinus alkaloid scandine has been synthesized. The synthetic strategy features two key steps: (1) a tandem nitroalkene conjugate addition/[3+2] cycloaddition of the resulting silyl nitronate and (2) an intramolecular Heck reaction of an aryl iodide with a ,-disubstituted allylic alcohol which set a highly congested, quaternary stereogenic center with the concomitant formation of an aldehyde. Intramolecular reductive amination with this aldehyde completed the pentacyclic core. [source]

Intramolecular Formal Aza-[3 + 3] Cycloaddition Approach to Indoloquinolizidine Alkaloids.

CHEMINFORM, Issue 15 2004
A Stereoselective Total Synthesis of (.+-.)-Tangutorine.
No abstract is available for this article. [source]

ChemInform Abstract: Synthesis of 1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid (Tic) Derivatives by Cycloaddition Approaches.

CHEMINFORM, Issue 18 2002
Sambasivarao Kotha
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

Cycloaddition approach to the curing of polyimides via precursor containing thiophene- S,S -dioxide

HETEROATOM CHEMISTRY, Issue 7 2006
Andrew Magyarosy
A new method for linear polymerization of maleimides via the Diels,Alder reaction has been developed. This method involves use of a new cross-linking agent, benzene-3,4-dimethylenesuccinimide, which can be generated in situ from its thiophene precursor, benzene-2,5-dihydrothiophene-3,4-dicarboximide- S,S -dioxide. This new cross-linking agent is reasonably reactive, readily prepared, and stable at room temperature. A controlled molecular weight oligomer has been synthesized and applied to the polymerization to yield a highly thermal stable polyimide. © 2006 Wiley Periodicals, Inc. Heteroatom Chem 17:648,652, 2006; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20249 [source]

Stereocontrolled Preparation of Fully Substituted Cyclopentanes: Relevance to Total Synthesis

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 10 2009
Brian Heasley
Abstract This Microreview aims to identify important advances in the asymmetric synthesis of fully substituted five-membered carbocyclic ring systems. Recent efforts directed towards the intricate and densely functionalized core substructures of three distinct classes of cyclopentane-based natural products will be examined. Strategies featuring high levels of stereocontrol and/or conciseness in the total number of synthetic steps required to access complex natural product ring fragments are highlighted. Stereoselective Diels,Alder cycloaddition approaches to access functionalized norbornene intermediates as latent chiral cyclopentanes in the tradition of Corey's elegant prostaglandin studies are a recurring theme. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009) [source]