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Curve Method (curve + method)
Selected AbstractsAccuracy of the Calibration Curve Method for Absorbed Dose Assessment in Irradiated Refrigerated Chicken BoneJOURNAL OF FOOD SCIENCE, Issue 1 2001A.A. Basfar ABSTRACT: The influence of the decay of the radiation induced free radicals on electron spin resonance (ESR) bone dosimetry was studied. The absorbed doses in irradiated bone are usually assessed by applying correction factors for decay. An alternative procedure is presented in which the ESR readout was performed only when the ESR signal had reached good stability for the bone samples used to establish the calibration curves and also on bones for which absorbed dose assessment was to be made. The results of the evaluated doses obtained by using this approach were the same as the ones obtained by using corrections for the decay of ESR signals. [source] Glass forming ability and nanocrystallization kinetics of Fe65Nb10B25 metallic glassesPHYSICA STATUS SOLIDI (A) APPLICATIONS AND MATERIALS SCIENCE, Issue 5 2010J. Torrens-Serra Abstract In this work the mechanisms controlling the nanocrystallization kinetics of the Fe65Nb10B25 metallic glasses have been determined by the combination of the analysis microstructural data from XRD and TEM, and the kinetic analysis performed using the Master Curve method of the continuous heating and isothermal calorimetric curves. The results show that the transformation starts by the nucleation and interface controlled growth of the Fe23B6 -type phase that changes to diffusion controlled growth as the transformation advances until is stopped by the soft-impingement effect. The transformation is modeled in the framework of the Kolmogorov,Johnson,Mehl,Avrami (KJMA) theory using constant activation energy expressions for the nucleation frequency and interface-controlled growth and taking into account the reduction of those quantities with the transformed fraction due to the change in the matrix composition using a mean-field approximation. The parameters of the modeling are determined from the coupling between the isothermal and constant heating rate calorimetric analysis and from the quantitative analysis of microstructural data. This is the outset for the determination of the viscosity, driving force for crystallization, and interfacial energy when replacing the constant activation energy expressions by the classical nucleation and growth ones. Both the glass forming ability in Fe,Nb,B based bulk metallic glasses and the temperature dependence of the interfacial energy are discussed in terms of the influence of the minor alloying elements. [source] What changes in health-related quality of life matter to multiple myeloma patients?EUROPEAN JOURNAL OF HAEMATOLOGY, Issue 4 2010A prospective study Abstract Objective: To determine the clinical significance of changes in quality-of-life scores in patients with multiple myeloma (MM), we have estimated the minimal important difference (MID) for the health-related quality-of-life instrument, the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30. The MID is the smallest change in a quality-of-life score considered important to patients. Methods: Between 2006 and 2008, 239 patients with MM completed the EORTC QLQ-C30 at inclusion (T1) and after 3 months (T2). At T2, a structured quality-of-life interview was also performed. MIDs were calculated by using mean score changes (T2,T1) for patients who in the interview stated they had improved, deteriorated or were unchanged. MIDs were also estimated by the receiver-operating characteristic (ROC) curve method as well as by calculation effect sizes using standard deviations of baseline scores. Results: MIDs varied slightly depending on the method used. Patients stating in the interview that they had ,improved' or ,deteriorated' had a corresponding change in EORTC QLQ-C30 score ranging from 6 to15 (improvement) and from 9 to17 (deterioration) (scale range 0,100). The ROC analysis indicated that changes in score from 7 to17 represent clinically important changes to patients. The effect size method suggested 5,6 to be a small and 11,15 to be a medium change. Conclusion: Calculation of MIDs as mean score changes or by ROC analysis suggested that a change in the EORTC QLQ-C30 score in the range of approximately 6,17 is considered important by patients with MM. These MIDs are closer to a medium effect size than to a small effect size. Our findings imply that mean score changes smaller than 6 are unlikely to be important to the patients, even if these changes are statistically significant. [source] Identification of protein-coding genes in the genome of Vibrio cholerae with more than 98% accuracy using occurrence frequencies of single nucleotidesFEBS JOURNAL, Issue 15 2001Ju Wang The published sequence of the Vibrio cholerae genome indicates that, in addition to the genes that encode proteins of known and unknown function, there are 1577 ORFs identified as conserved hypothetical or hypothetical gene candidates. Because the annotation is not 100% accurate, it is not known which of the 1577 ORFs are true protein-coding genes. In this paper, an algorithm based on the Z curve method, with sensitivity, specificity and accuracy greater than 98%, is used to solve this problem. Twenty-fold cross-validation tests show that the accuracy of the algorithm is 98.8%. A detailed discussion of the mechanism of the algorithm is also presented. It was found that 172 of the 1577 ORFs are unlikely to be protein-coding genes. The number of protein-coding genes in the V. cholerae genome was re-estimated and found to be ,,3716. This result should be of use in microarray analysis of gene expression in the genome, because the cost of preparing chips may be somewhat decreased. A computer program was written to calculate a coding score called VCZ for gene identification in the genome. Coding/noncoding is simply determined by VCZ > 0/VCZ < 0. The program is freely available on request for academic use. [source] Peptone preparation from fishing by-productsJOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, Issue 7 2005Gustavo HF Vieira Abstract Panulirus argus and P laevicauda lobster carapace meat, lobster tail parings, whole shrimp tails from Cinnamon shrimp, (Macrobachium amazonicum) and scraps left over from filleting Piaui croaker (Plagioscion squamosissimus) were separated, hydrolysed and then lyophilised and used as individual sources of peptone in media for the cultivation of Escherichia coli. The composition of the test media was: 0.3% meat extract, 0.5% peptone and 0.1% lactose. These new sources of peptone were compared with commercially obtained peptone (OXOID), commonly used in laboratory media, and which served as the control. E coli growth curves for each source of peptone were evaluated using the turbidimetry method and biomass quantification was determined by the dry curve method in order to obtain the respective growth rates for these media. E coli grew faster and for longer using alternative sources of peptone than with the control. The peptone yield from lobster carapace meat was 17.6%, from lobster tail parings 10.2%, from Piaui croaker fish scraps 23% and from whole Ciannamon shrimp tails 12.9%. Growth curves and the biomass figures indicate the feasibility of using these fishery by-products as raw materials for peptone production for microbial media. Copyright © 2005 Society of Chemical Industry [source] | ||||||||||