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Adult Female Patient (adult + female_patient)
Selected AbstractsAccidental displacement of a mandibular third molar crown into the parapharyngeal space during extractionORAL SURGERY, Issue 2 2008K. Kamburo Abstract An unusual accidental displacement of a mandibular third molar crown into the parapharayngeal space in an adult female patient is reported. In combination with clinical examination, conventional and advanced radiographic techniques were utilised in order to locate the crown for retrieval surgery. Under general anaesthesia, an incision starting from buccal sulcus towards distobuccal angle of the second molar at gingival margin was extended to the coronoid process. The dislodged crown was found by means of blunt dissection and grasped with a pair of artery forceps and removed. [source] An adult female patient with ring chromosome 21: behavioural phenotype and results of high-resolution molecular characterisationACTA NEUROPSYCHIATRICA, Issue 4 2010Willem M.A. Verhoeven Verhoeven WMA, Bon BV, Egger JIM, Hoischen A, Doelman JC. An adult female patient with ring chromosome 21: behavioural phenotype and results of high-resolution molecular characterisation. Objective: A female adult patient with mild to moderate mental retardation and minor dysmorphisms was referred for neuropsychiatric examination because of psychotic and autistic symptoms and impulsive behaviours. Methods: Standardized neuropsychiatric and neuropsychological assessment as well as detailed somatic and neurological examination was performed. For genetic analysis, karyotyping, whole genome array analysis, and high-resolution detailed analysis of chromosome 21 were carried through. Results: Karyotyping showed a de novo ring chromosome 21: 46,XX,der(21)r(21)(p11q22.3). High-resolution array analysis demonstrated a complex aberration consisting of an interstitial duplication in 21q21.1, an interstitial deletion in 21q22.2q22.3, an interstitial deletion in 21q22.3 and a terminal deletion of 21q22.3. Apart from mild dysmorphisms, visual and auditory impairments, and infertility, no somatic or neurological abnormalities were found. A formal psychiatric diagnosis could not be established. The behavioural problems and the supposed psychiatric symptoms could be related to her disharmonic social cognitive profile. The behaviour normalized after the patient returned to a stable and structured living environment. Conclusion: High-resolution micro-array analysis techniques are essential to substantiate the genotype,phenotype correlation in patients with r(21) and other genetic disorders. Moreover, the results of this study stress the importance of the recognition of alexithymia as a potential cause for behavioural problems and psychiatric symptoms in patients with mental retardation in general. [source] Fludarabine, cyclophosphamide, anti-thymocyteglobulin, and low-dose total body irradiation conditioning enables 1-HLA-locus-mismatched hematopoietic stem cell transplantation for very severe aplastic anemia without affecting ovarian functionAMERICAN JOURNAL OF HEMATOLOGY, Issue 3 2009Shinya Okuda Allogeneic hematopoietic stem cell transplantation for severe aplastic anemia from an alternative donor is associated with higher risks of graft rejection and severe graft-versus-host disease. We developed a conditioning regimen consisting of rabbit anti-thymocyte globulin, fludarabine, cyclophosphamide, and low-dose total body irradiation. Two adult female patients with transfusion-dependent very severe aplastic anemia underwent 1-locus mismatched transplantation using this regimen. Both patients achieved stable engraftment and the clinical course thereafter was uneventful with persistently normal ovarian function. This novel conditioning regimen may be suitable for alternative donor transplantation for severe aplastic anemia, especially in young female patients. Am. J. Hematol. 2009. © 2008 Wiley-Liss, Inc. [source] Treatment of erosive vulvovaginal lichen planus with methotrexateAUSTRALASIAN JOURNAL OF DERMATOLOGY, Issue 4 2008Nelly Jang SUMMARY We report the successful treatment of severe long-standing erosive vulvovaginal lichen planus in four adult female patients using 2.5,7.5 mg of oral methotrexate once weekly in conjunction with topical clobetasol dipropionate 0.05% ointment and tacrolimus 0.03,0.10% ointment. All cases experienced improvement in symptoms and healing of lesions within 4,8 weeks. Methotrexate was well tolerated and no adverse events have been observed in any of the patients at follow up 4,6 months later. [source] | ||||||||||