Cover Picture (cover + picture)

Distribution by Scientific Domains


Selected Abstracts


Proteomics , Clinical Applications (Cover Picture 21/2006)

PROTEINS: STRUCTURE, FUNCTION AND BIOINFORMATICS, Issue 21 2006
Article first published online: 26 OCT 200
No abstracts. [source]


Proteomics , Clinical Applications (Cover Picture 19/2006)

PROTEINS: STRUCTURE, FUNCTION AND BIOINFORMATICS, Issue 19 2006
Article first published online: 2 OCT 200
No abstracts. [source]


Corrigendum: Cover Picture: Discovery of a Class of Diketopiperazines as Antiprion Compounds (ChemMedChem 8/2010)

CHEMMEDCHEM, Issue 9 2010
Maria Laura Bolognesi Prof.
No abstract is available for this article. [source]


Cover Picture: Synthesis of Gadolinium-Labeled Shell-Crosslinked Nanoparticles for Magnetic Resonance Imaging Applications (Adv. Funct.

ADVANCED FUNCTIONAL MATERIALS, Issue 8 2005
Mater.
Abstract Robust, amphiphilic core,shell nanoparticles that are selectively labeled with gadolinium in the hydrophilic and water-swollen shell layer are depicted in the cover picture. These well-defined nanostructured materials exhibit high relaxivity, a large loading capacity, and are based upon a biocompatible platform for ultimate function in magnetic resonance imaging (MRI) applications, as reported by Wooley and co-workers on p.,1248. Shell-crosslinked knedel-like nanoparticles (SCKs; "knedel" is a Polish term for dumplings) were derivatized with gadolinium chelates and studied as robust magnetic-resonance-imaging-active structures with hydrodynamic diameters of 40,±,3,nm. SCKs possessing an amphiphilic core,shell morphology were produced from the aqueous assembly of diblock copolymers of poly-(acrylic acid) (PAA) and poly(methyl acrylate) (PMA), PAA52,b,PMA128, and subsequent covalent crosslinking by amidation upon reaction with 2,2,-(ethylenedioxy)bis(ethylamine) throughout the shell layer. The properties of these materials, including non-toxicity towards mammalian cells, non-immunogenicity within mice, and capability for polyvalent targeting, make them ideal candidates for utilization within biological systems. The synthesis of SCKs derivatized with GdIII and designed for potential use as a unique nanometer-scale contrast agent for MRI applications is described herein. Utilization of an amino-functionalized diethylenetriaminepentaacetic acid,Gd analogue allowed for direct covalent conjugation throughout the hydrophilic shell layer of the SCKs and served to increase the rotational correlation lifetime of the Gd. In addition, the highly hydrated nature of the shell layer in which the Gd was located allowed for rapid water exchange; thus, the resulting material demonstrated large ionic relaxivities (39,s,1,mM,1) in an applied magnetic field of 0.47,T at 40,°C and, as a result of the large loading capacity of the material, also demonstrated high molecular relaxivities (20,000,s,1,mM,1). [source]


Cover Picture: J. Biophoton.

JOURNAL OF BIOPHOTONICS, Issue 7 2010
7/2010
Video rate STED Nanoscopy visualizes the motion of neurotransmitter vesicles in living neurons. A STED highresolution movie (front filmstrip) resolves individual objects in the axons. In contrast, a confocal movie (back filmstrip) shows only unspecific motion. (Picture: M. A. Lauterbach et al., see also pp. 417,424 in this issue) The authors thank Hartmut Sebesse (Printing and Graphics Office of the Max Planck Institute for Biophysical Chemistry) for his skillful help in preparing the cover picture (© 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim) [source]


6th International Workshop on Expert Evaluation & Control of Compound Semiconductor Materials & Technologies

PHYSICA STATUS SOLIDI (A) APPLICATIONS AND MATERIALS SCIENCE, Issue 1 2003
Bálint P
The EXMATEC workshops are a series of biannial conferences with the aim to bring together research and development specialists involved in compound semiconductor material physics, chemistry, process technology, characterization and device fabrication. EXMATEC 2002 is the continuation of successful meetings, previously held in Lyon, Parma, Freiburg, Cardiff and Heraklion. The central topics were development, improvement and application of new and advanced methods in the fabrication and evaluation of compound semiconductor materials and structures to develop understanding of the interrelationship between structural, electrical and other material properties and device characteristics, such as performance, reliability, reproducibility, lifetime, yield, etc. The conference topics apply to all compound semiconductor materials (III,V, II,VI, IV,IV, II,IV,V2), related structures and processing steps (from substrate and epitaxial growth to complete devices) and cover instrumentation and characterization issues. The full Proceedings of EXMATEC 2002 are published in the second issue of the new journal series physica status solidi , conferences Vol. 0, No. 2 (2003). As one representative example of the topics presented at this conference, the cover picture of the present issue issue of phys. stat. sol. (a) shows the band scheme of a typical GaInAs/AlInAs superlattice quantum cascade laser, taken from the invited paper by Razeghi and Slivken [1]. [source]


Computer simulations of protein translocation

PHYSICA STATUS SOLIDI (B) BASIC SOLID STATE PHYSICS, Issue 9 2006
Serdal Kirmizialtin
Many biological processes involve translocation of protein molecules across pores. Shown in the cover picture of this issue is a snapshot from a computer simulation of the protein ubiquitin that is forced mechanically to enter a narrow cylindrical pore. As the force f applied at one end of the molecule pulls it along the pore, the confinement within the pore causes the protein to unfold. The ensuing changes in the protein's entropy and energy lead to a free energy barrier, which has to be surmounted for the translocation to occur. The magnitude of this barrier is estimated by Kirmizialtin et al. in the article [1]. The plot was generated by using the PyMol software. This paper is a presentation from the 1st Institute for the Theory of Advanced Materials in Information Technology Workshop on Computational Materials and Electronics held 20,22 October 2005 in Austin, USA. The present issue has been guest-edited by James Chelikowsky and Alex Demkov. The background of the cover shows a photograph of the tower of the University of Texas at Austin. (© 2006 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim) [source]