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Cost Pressure (cost + pressure)
Selected AbstractsAcetylcholinesterase treatment,modelling potential demand and auditing practiceINTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, Issue 12 2001Simon Lovestone Abstract Background Acetylcholinesterase inhibitors represent an entirely novel treatment option for patients with Alzheimer's disease (AD). As such they represent a significant change in practice and a significant cost pressure on funding bodies. Objectives To assess the impact of cholinesterase inhibitors on routine clinical practice. Methods We estimated potential demand for the compounds taking into account eligibility criteria and prescribing practice agreed between clinicians and funders. We then audited actual prescribing practice assessing whether the estimated demand matched actual demand and whether practice and prescribing criteria were adhered to. Results Over a two-year period we estimated the demand for treatment at a total of 89 patient years for the population of the audit unit. In practice only 24.5 patient years of therapy were received, the short fall apparently being due to low referral rates for treatment. Prescribing by clinicians matched practice guidelines and a high proportion of three monthly assessments using scales for cognition, function and global state were performed. Using these assessment procedures treatment successes could be differentiated from primary and secondary treatment failures and, where apparently appropriate, treatment could be stopped. Conclusion In the real world of clinical practice demand for treatment in AD is modest but likely to grow and assessment with an aim to identifying those receiving benefit from treatment can be achieved. Copyright © 2001 John Wiley & Sons, Ltd. [source] TESTING WAGE AND PRICE PHILLIPS CURVES FOR THE UNITED STATESMETROECONOMICA, Issue 4 2007Peter Flaschel ABSTRACT This paper demonstrates how the labour and product markets interact in determining as outcome a generalized reduced-form price Phillips curve. For the labour market we consider a wage Phillips curve and for the product market a price Phillips curve. We estimate separately the wage and price Phillips curves for the USA, using ordinary least squares, non-parametric estimation and three-stage least squares techniques. The finding is that wages are always more flexible than prices with respect to their respective demand pressure and that price inflation responds somewhat more to a medium-run cost pressure than does wage inflation. The implications for macroeconomic stability are demonstrated. We also show,as a link between product and labour markets,that employment is related to output as Okun's law states. In comparing linear and non-linear estimates of the wage and price Phillips curves we find furthermore that for some relationships non-linearities are important while not for others. Although overall the non-linear estimates tend to confirm our linear estimates, non-linearities in some relationships of the Phillips curve are important as well. [source] Open innovation in the automotive industryR & D MANAGEMENT, Issue 3 2010Serhan Ili Automotive Original Equipment Manufacturers (OEM) have historically invested in their own research and development (R&D) to boost their innovativeness. Because of an increasing innovation and cost pressure, the automotive industry needs to look outside their own boundaries to escape from this productivity dilemma. While there is a tendency to look outside for external sources to increase the innovativeness, there are hardly any external paths to market outside the current business yet. Our study shows that Open Innovation proves to be more adequate in the attempt to achieve a better R&D productivity for companies in the automotive industry than a closed innovation model. [source] Strengthening Research to Improve the Practice and Management of Long-Term CareTHE MILBANK QUARTERLY, Issue 2 2003PENNY HOLLANDER FELDMAN Chronic disease and disability affect Americans of all ages, and millions rely on long-term care (LTC) services,in nursing facilities, in congregate residences, or at home,to meet their health and personal assistance needs. People who are 65 years old today have about a 40 percent chance of spending some time in a nursing home before they die (Kemper and Murtaugh 1991; Murtaugh, Kemper, and Spillman 1990). Almost three-quarters will have had some experience with home care (Stone 2000). The numbers of people, both young and old, in need of long-term care are growing. Changing demographics, a more engaged public, and growing cost pressures are increasing the demand for empirical evidence of the effectiveness and cost effectiveness of alternative LTC approaches and practices. Making the formal LTC system more effective and more efficient requires that research play a more prominent role in informing service delivery. The research agenda should both respond to and push forward the field of practice, and the definitions of appropriate topics should come from both the practitioners and the researchers. [source] Disposable bioprocessing: The future has arrivedBIOTECHNOLOGY & BIOENGINEERING, Issue 2 2009Govind Rao Abstract Increasing cost pressures are driving the rapid adoption of disposables in bioprocessing. While well ensconced in lab-scale operations, the lower operating/ validation costs at larger scale and relative ease of use are leading to these systems entering all stages and operations of a typical biopharmaceutical manufacturing process. Here, we focus on progress made in the incorporation of disposable equipment with sensor technology in bioprocessing throughout the development cycle. We note that sensor patch technology is mostly being adapted to disposable cell culture devices, but future adaptation to downstream steps is conceivable. Lastly, regulatory requirements are also briefly assessed in the context of disposables and the Process Analytical Technologies (PAT) and Quality by Design (QbD) initiatives. Biotechnol. Bioeng. 2009;102: 348,356. © 2008 Wiley Periodicals, Inc. [source] | |||||||||||||