Cope

Distribution by Scientific Domains

Terms modified by Cope

  • cope rearrangement
  • cope rule

  • Selected Abstracts


    CHANNING COPE AND THE MAKING OF A MIRACLE VINE,

    GEOGRAPHICAL REVIEW, Issue 2 2004
    DEREK H. ALDERMAN
    ABSTRACT. The history of kudzu illustrates the fluidity with which people can redefine their cultural relationship with exotic species. Although much of American society views the fast-growing Asian vine as a pest, this has not always been the case. During the first half of the twentieth century, individual entrepreneurs and government officials touted kudzu as a "miracle vine" and carried out massive planting campaigns across the southeastern United States. This study traces the changing place of kudzu within southern society from its introduction in the late 1800s to the present. Specific attention is devoted to the role that the gentleman farmer, author, and radio personality Channing Cope played in popularizing the cultivation of kudzu. Cope's promotional activities are interpreted as environmental claims making. Analysis focuses on the metaphors he used in persuading the public of kudzu's supposed benefits. Conducting such an examination advances our general understanding of the historical geography of exotics in America and the importance of human agency and cultural representation in the spread of non-native organisms. [source]


    Psychological aspects and coping styles of parents with Haemophilic child undergoing a programme of counselling and psychological support

    HAEMOPHILIA, Issue 3 2007
    A. M. BOTTOS
    Summary., Parents of children affected by haemophilia must face, often without prior knowledge, the difficult challenge imposed by such a pathology. To satisfy the need of information, guideline and psychological support for a better quality of life, 30 parents with haemophiliac children have participated in a programme of counselling and psychological support. Such a programme has the aim of guiding the group trough a process of discovery, comparison and personal growth and stimulating adaptive processes of problem,solving and decision,making. The aim of this paper was to verify how the programme influenced coping strategies and other psychological constructs such as depression and anxiety. Subjects of this study were administered the following psychological tests: COPE (coping, orientation to problems experienced), BDI (beck depression inventory), STAI-Y form (state,trait anxiety inventory) at the beginning and at the end of the programme. The results show that by the end of the programme subjects are characterized by a greater use of problem,focused coping strategies, typical of individuals who think that the situation is susceptible to change, and a minor use of emotion,focused coping strategies, related to individuals who regard the situation as immutable. The use of avoidance ,focused coping strategies seems to remain at the same level even if it was low. Also the other psychological aspects investigated, namely depression and anxiety, did receive a positive influence. The results show how significant such programme has been for parents. [source]


    Comparing Structural Equation Models That Use Different Measures of the Level of Response to Alcohol

    ALCOHOLISM, Issue 5 2010
    Marc A. Schuckit
    Background:, The two measures of a low level of response (LR) to alcohol, an alcohol challenge and the retrospective Self-Report of the Effects of Alcohol questionnaire (SRE), each identify individuals at high risk for heavy drinking and alcohol problems. These measures also perform similarly in identifying subjects with unique functional brain imaging characteristics. However, few data are available regarding whether alcohol challenge-based and SRE-based LRs operate similarly in structural equation models (SEMs) that search for characteristics, which help to mediate how LR impacts alcohol outcomes. Methods:, Two hundred and ninety-four men from the San Diego Prospective Study were evaluated for their LR to alcohol using alcohol challenges at ,age 20. At ,age 35, the same subjects filled out the SRE regarding the number of drinks needed for effects 15 to 20 years earlier. The two different LR scores for these men were used in SEM analyses evaluating how LR relates to future heavy drinking and to drinking in peers (PEER), alcohol expectancies (EXPECT), and drinking to cope (COPE) as potential mediators of the LR to drinking pattern (ALCOUT) relationships. Results:, While the 2 LR measures that were determined 15 years apart related to each other at a modest level (r = 0.17, p < 0.01), the SEM results were similar regardless of the LR source. In both alcohol challenge-based and SRE-based LR models, LR related directly to ALCOUT, with partial mediation from PEER and COPE, but not through EXPECT in these 35-year-old men. Conclusions:, Consistent with the >60% overlap in prediction of outcomes for the 2 LR measures, and with results from functional brain imaging, alcohol challenge- and SRE-based LR values operated similarly in SEM models in these men. [source]


    Improving the Mental Health, Healthy Lifestyle Choices, and Physical Health of Hispanic Adolescents: A Randomized Controlled Pilot Study

    JOURNAL OF SCHOOL HEALTH, Issue 12 2009
    Bernadette M. Melnyk PhD, CPNP/NPP, FAAN
    ABSTRACT BACKGROUND: Obesity and mental health disorders are 2 major public health problems in American adolescents, with prevalence even higher in Hispanic teens. Despite the rapidly increasing incidence and adverse health outcomes associated with overweight and mental health problems, very few intervention studies have been conducted with adolescents to improve both their healthy lifestyles and mental health outcomes. Even fewer studies have been conducted with Hispanic youth. The purpose of this study was to evaluate the preliminary efficacy of the COPE (Creating Opportunities for Personal Empowerment) Healthy Lifestyles TEEN (Thinking, Emotions, Exercise, and Nutrition) program, a manualized educational and cognitive behavioral skills-building program, on Hispanic adolescents' healthy lifestyle choices as well as mental and physical health outcomes. METHODS: A cluster randomized controlled pilot study was conducted with 19 Hispanic adolescents enrolled in 2 health classes in a southwestern high school. One class received COPE and the other received an attention control program. RESULTS: Adolescents in the COPE program increased their healthy lifestyle choices and reported a decrease in depressive and anxiety symptoms from baseline to postintervention follow-up. A subset of 7 overweight adolescents in the COPE program had a decrease in triglycerides and an increase in high-density lipoproteins. In addition, these overweight adolescents reported increases in healthy lifestyle beliefs and nutrition knowledge along with a decrease in depressive symptoms. CONCLUSION: The COPE TEEN program is a promising school-based strategy for improving both physical and mental health outcomes in adolescents. [source]


    Caring for a person with dementia: Exploring relationships between perceived burden, depression, coping and well-being

    NURSING & HEALTH SCIENCES, Issue 2 2005
    Ronelle McConaghy
    Abstract This study was concerned with identifying the impact of variables such as gender, length of time caring, coping style, depression and perception of caregiving burden on the physical and psychological well-being of carers of persons with dementia. Forty-two carers aged between 21 and 88 years from Blue Care's Homecare Dementia Service and Cairns Aged Care Health Service participated in the study. A cross-sectional survey research design was used, with participants providing information on the Satisfaction with Life Scale, the Center for Epidemiologic Studies Depression Scale, the COPE, Short Form (SF)-12 and the Zarit Caregiver Burden Scale. Perceived burden accounted for 41.7% of the variance in satisfaction with life as a subjective measure of well-being. There were no significant differences between male and female carers. Satisfaction with life was not found to decrease with length of time caring for the dementia sufferer. There were no significant findings in regard to coping style or physical health of carers. The well-being of carers can be enhanced through strategies which lead to a reduced perception of burden, with respite services providing tangible relief from burden. [source]


    Outcomes after trans-tibial amputation: the relationship between quiet stance ability, strength of hip abductor muscles and gait

    PHYSIOTHERAPY RESEARCH INTERNATIONAL, Issue 4 2002
    Heidi Nadollek
    Abstract Background and Purpose Previous research regarding the symmetry of trans-tibial amputees has examined weight distribution and various gait parameters between prosthetic and sound limbs. However, to date, no known research has determined if asymmetry is present in the strength of the hip abductor muscles or if correlations exist between these categories of symmetry. The purpose of the present study was, therefore, to document asymmetry present in stance, strength and gait measures, and to determine the relationship between these variables. Method Twenty-three elderly, unilateral trans-tibial amputees stood on two adjacent forceplates whilst the weight distribution and standard deviation (SD) of the anterior-posterior and the medio-lateral centre of pressure excursion (COPE) under each limb was recorded during four 40 s trials: quiet stance (QS), with eyes open and eyes closed; and even stance (ES), with eyes open and eyes closed. Gait measures (velocity, cadence, step and stride lengths, stance:swing ratio and period of double support) over 10 m of fast, yet safe walking and measures of the strength of hip abductor muscles were also obtained by use of a stride analyser and a dynamometer, respectively. Results No significant differences were found between QS and ES measures. However, significantly more weight was taken on the sound limb than on the amputated limb. Notably, more anterior-posterior movement occurred under the sound limb than the amputated limb, with this becoming more apparent with the eyes closed. Movement in the medio-lateral direction was found to be the same between sides. No differences in muscle strength or gait measures between limbs were demonstrated. However. strong hip abductor muscles were correlated with increased weight-bearing on the amputated limb, improved gait parameters and reduced medio-lateral COPE under the amputated limb. Conclusions This research confirms the asymmetrical nature of amputee stance and demonstrates symmetry of strength and gait measures between limbs. The correlations between hip abductor muscle strength, weight distribution and gait measures illustrates the importance of pre- and postoperative training of these muscles. Copyright © 2002 Whurr Publishers Ltd. [source]


    Improving cognitive development of low-birth-weight premature infants with the COPE program: A pilot study of the benefit of early NICU intervention with mothers

    RESEARCH IN NURSING & HEALTH, Issue 5 2001
    Bernadette Mazurek Melnyk
    Abstract The purpose of this pilot study was to evaluate the effectiveness of a parent-focused intervention program (COPE) on infant cognitive development and maternal coping. A randomized clinical trial was conducted with 42 mothers of low-birth-weight (LBW) premature infants hospitalized in a neonatal intensive care unit (NICU), with follow-up at 3 months' and 6 months' corrected ages. COPE mothers received the four-phase educational,behavioral program that began 2,4 days postbirth and continued through 1 week following discharge from the NICU. Comparison mothers received audiotaped information during the same four time frames. Results indicated that COPE infants had significantly higher mental development scores at a 3 months' corrected age (M,=,100.3) than did the comparison infants (M,=,93.9), and this difference widened at 6 months' corrected age, with COPE infants scoring 14 points higher. COPE mothers were significantly less stressed by the NICU sights and sounds and had significantly stronger beliefs about what behaviors and characteristics to expect from their premature infants. Findings from this study support the need for further testing of early NICU interventions with parents to determine their effectiveness on parental coping and infant developmental outcomes. © 2001 John Wiley & Sons, Inc. Res Nurs Health 24:373,389, 2001 [source]


    Committee on Publication Ethics (COPE): guidelines on good publication practice

    BJU INTERNATIONAL, Issue 1 2000
    Article first published online: 10 DEC 200
    First page of article [source]


    Israeli Kindergarten Teachers Cope With Terror and War: Two Implicit Models of Resilience

    CURRICULUM INQUIRY, Issue 1 2007
    DAVID BRODY
    ABSTRACT The resilience of teachers in the face of terror was examined in a narrative study of two Israeli kindergarten teachers over the course of one school year. During this time, there occurred frequent terror attacks as well as the threat of impending war with Iraq and the concomitant threat of chemical warfare. Each teacher's unique pattern of coping based on her own personal theory of resilience was examined. One teacher actively processed with her students stressful news items that the children had encountered. This was based on her belief that children would become more resilient if they had experience dealing with stress in a mediated fashion. The second teacher chose to create what she perceived to be a comfort zone for her students by actively avoiding open discussion about stressful events. She chose to focus on enhancing self-esteem, self-efficacy, and optimism, which she believed would produce greater resilience in her students. In developing these personal resilience theories, both teachers were able to move out of a paralyzed position that is typical of crisis and the immediate posttraumatic period, and move into active coping, thereby incorporating their unique theories of resilience into their personal professional knowledge. These practices were examined in light of current resilience theory. [source]


    The effects of epibenthic communities on reef fishes in the northern Gulf of Mexico

    FISHERIES MANAGEMENT & ECOLOGY, Issue 5 2009
    R. A. REDMAN
    Abstract, Reef fishes were compared between artificial reefs with (n = 20) and without (n = 20) epibenthic communities in the northern Gulf of Mexico. Artificial reefs were built in June 2003; half were coated with copper-based paint to prevent epibenthic community development. Reefs were surveyed by SCUBA divers to estimate fish abundance in the autumn and winter 2003 and spring 2004. Total fish abundance and abundance of red snapper, Lutjanus campechanus (Poey), and gray triggerfish, Balistes capriscus Gmelin, were significantly (P , 0.05) higher on reefs with epibenthic communities. In the spring 2004, the abundance of belted sandfish, Serranus subligarius (Cope), the size of red snapper and community measures of diversity and evenness were significantly (P , 0.05) greater on unpainted reefs. These significant differences provide evidence that reef fishes were positively affected by the presence of epibenthic organisms that probably provided increased food resources. [source]


    Anxiety and the True Beginner,False Beginner Dynamic in Beginning French and Spanish Classes

    FOREIGN LANGUAGE ANNALS, Issue 2 2005
    Diana Frantzen
    Abstract: This study considered true beginners and false beginners in first-semester university French and Spanish classes to: (a) determine whether true beginners and false beginners differ in anxiety, grades, and plans to continue language study; and (b) identify classroom factors that foster anxiety or comfort. Students completed a questionnaire that included the Foreign Language Classroom Anxiety Scale (Horwitz, Horwitz, & Cope, 1986), MacIntyre and Gardner Anxiety Subscales (1989, 1994), demographic information, grade expectations, and open-ended questions. Randomly selected students were interviewed about their experiences in the courses. Statistical analyses revealed that (a) although neither group was terribly anxious, true beginners were significantly more anxious overall and during processing and output stages than false beginners; (b) true beginners expected and received lower grades than false beginners; and (c) significantly more true beginners than false beginners planned to continue studying the language. Comments on one written open-ended question and in the interviews pointed to the key role of the instructor in reducing anxiety. [source]


    CHANNING COPE AND THE MAKING OF A MIRACLE VINE,

    GEOGRAPHICAL REVIEW, Issue 2 2004
    DEREK H. ALDERMAN
    ABSTRACT. The history of kudzu illustrates the fluidity with which people can redefine their cultural relationship with exotic species. Although much of American society views the fast-growing Asian vine as a pest, this has not always been the case. During the first half of the twentieth century, individual entrepreneurs and government officials touted kudzu as a "miracle vine" and carried out massive planting campaigns across the southeastern United States. This study traces the changing place of kudzu within southern society from its introduction in the late 1800s to the present. Specific attention is devoted to the role that the gentleman farmer, author, and radio personality Channing Cope played in popularizing the cultivation of kudzu. Cope's promotional activities are interpreted as environmental claims making. Analysis focuses on the metaphors he used in persuading the public of kudzu's supposed benefits. Conducting such an examination advances our general understanding of the historical geography of exotics in America and the importance of human agency and cultural representation in the spread of non-native organisms. [source]


    The effect of body size on food consumption, absorption efficiency, respiration, and ammonia excretion by the inland silverside, Menidia beryllina (Cope) (Osteichthyes: Atherinidae)

    JOURNAL OF APPLIED ICHTHYOLOGY, Issue 4 2003
    M. A. Peck
    Summary The inland silverside, Menidia beryllina (Cope), is an annual zooplanktivore that occurs in estuarine and freshwater habitats along the Atlantic and Gulf of Mexico coasts and drainages of the United States. Experiments were conducted at 25 ± 1°C to quantify the relationship between mean dry weight (WD) and rates of energy gain from food consumption (C), and energy losses as a result of respiration (R) and ammonia excretion (E) during routine activity and feeding by groups of fish. The absorption efficiency of ingested food energy (A) was also quantified. Rates of C, E, and R increased with WD by factors (b in the equation y = aWDb) equal to 0.462, 0.667, and 0.784, respectively. Mean (±SE) rates of energy loss during feeding were 1.6 ± 0.1 (R) and 3.4 ± 0.6 (E) times greater than those for unfed fish. Absorption efficiency was independent of WD and estimated to be 89% of C. From these measurements, the surplus energy available for growth and activity (G) and growth efficiency (K1) were estimated. Over the range in sizes of juveniles and adults (5,500 mg WD), predicted G and K1 values decreased from 7.42 to 0.20 J mg fish,1 day,1 and 63 to 21%, respectively. Measured and predicted bioenergetic parameters are discussed within an ecological context for a northern population of this species. [source]


    The existence of secondary orbital interactions

    JOURNAL OF COMPUTATIONAL CHEMISTRY, Issue 1 2007
    Chaitanya S. Wannere
    Abstract B3LYP/6-311+G** (and MP2/6-311+G**) computations, performed for a series of Diels-Alder (DA) reactions, confirm that the endo transition states (TS) and the related Cope-TSs are favored energetically over the respective exo -TSs. Likewise, the computed magnetic properties (nucleus-independent chemical shifts and magnetic susceptibililties) of the endo - (as well as the Cope) TS's reveal their greater electron delocalization and greater aromaticity than the exo -TS's. However, Woodward and Hoffmann's original example is an exception: their endo -TS model, involving the DA reaction of a syn - with an anti -butadiene (BD), actually is disfavored energetically over the corresponding exo -TS; magnetic criteria also do not indicate the existence of SOI delocalization in either case. Instead, a strong energetic preference for endo -TSs due to SOI is found when both BDs are in the syn conformations. This is in accord with Alder and Stein's rule of "maximum accumulation of double bonds:" both the dienophile and the diene should have syn conformations. Plots along the IRC's show that the magnetic properties typically are most strongly exalted close to the energetic TS. Because of SOI, all the points along the endo reaction coordinates are more diatropic than along the corresponding exo pathways. We find weak SOI effects to be operative in the endo -TSs involved in the cycloadditions of cyclic alkenes, cyclopropene, aziridine, cyclobutene, and cyclopentene, with cyclopentadiene. While the endo -TSs are only slightly lower in energy than the respective exo -TSs, the magnetic properties of the endo -TS's are significantly exalted over those for the exo -TS's and the Natural Bond Orbitals indicate small stabilizing interactions between the methylene cycloalkene hydrogen orbitals (and lone pairs in case of aziridine) with ,-character and the diene , MOs. © 2006 Wiley Periodicals, Inc. J Comput Chem 2007 [source]


    The Stability of General Foreign Language Classroom Anxiety across English and French

    MODERN LANGUAGE JOURNAL, Issue 3 2003
    M´ximo Rodríguez
    The present study examined the stability of the general foreign language classroom anxiety construct across English and French. Preservice teachers from two western universities in Venezuela, who were majoring simultaneously in these two foreign languages, participated in the study. The students represented a variety of levels within each language. They completed two Spanish versions (one for each language) of the Foreign Language Classroom Anxiety Scale (FLCAS; Horwitz, Horwitz, & Cope, 1986). Separate analyses were performed on the full sample and on a restricted sample that included only those students who were at the same level in both languages. The results supported the indirect findings reported by Saito, Horwitz, and Garza (1999) while providing direct evidence suggesting the stability of the construct across English and French. Evidence obtained for overall, within-institution, and within-level comparisons. Furthermore, analysis of psychometric technical aspects of the FLCAS indicated that the scale exhibited high reliability but moderate construct validity. [source]


    Helping Children Cope in the Wake of Violence or Trauma

    THE BROWN UNIVERSITY CHILD AND ADOLESCENT BEHAVIOR LETTER, Issue S6 2007
    Article first published online: 9 MAY 200
    No abstract is available for this article. [source]


    Posttraumatic Symptoms, Functional Impairment, and Coping among Adolescents on Both Sides of the Israeli,Palestinian Conflict: A Cross-Cultural Approach

    APPLIED PSYCHOLOGY, Issue 4 2009
    Ruth Pat-Horenczyk
    This study assessed the effects of the ongoing violence on the mental health of Palestinian and Israeli youths. Parallel instruments were developed and adapted, as part of a collaborative project, in order to assess, in each society: (1) differential rates of exposure to the conflict, (2) the association between exposure and the severity of posttraumatic symptoms (PTS), and (3) the inter-relationships among PTS, functional impairment, somatic complaints, and coping strategies. Participants were 1,016 Israeli and 1,235 Palestinian adolescents. A self-report questionnaire assessed exposure. PTS was measured using the UCLA PTSD Reaction Index, functional impairment and somatic complaints were measured with the DISC, and coping strategies were assessed with Brief Cope. In both societies, greater exposure to conflict-related violence was associated with more PTS and more somatic complaints, with girls reporting more distress than boys. A total of 6.8 per cent of the Israeli students and 37.2 per cent of the Palestinian students met criteria for Post Traumatic Stress Disorder (PTSD). In both societies, but more pronounced in the Palestinian Authority, adolescents reported significant levels of functional impairment, mainly in the area of school functioning. Students with PTSD reported more somatic complaints as well as greater functional impairment. The results show the serious psychological impact of the ongoing violent conflict on Israeli and Palestinian students and point to the need to develop appropriate school-based interventions to address their mental health needs. Cette étude évalue les effets de la violence continuelle sur la santé mentale des jeunes palestiniens et israéliens. Des instruments analogues ont été développés et adaptés, dans le cadre d'un projet de collaboration, afin d'évaluer dans chaque société: (1) les différences de taux d'exposition au conflit, (2) l'association entre l'exposition et la sévérité des symptômes post-traumatiques (PTS) et (3) les interrelations entre les PTS, les troubles fonctionnels, les plaintes somatiques et les stratégies de faire-face. 1016 adolescents israéliens et 1235 adolescents palestiniens ont participéà cette étude. Un questionnaire auto-administré mesure l'exposition au conflit. Les PTS sont mesurés par l'utilisation de l'UCLA PTSD Reaction Index, les troubles fonctionnels et les plaintes somatiques sont approchés par le DISC, et les stratégies de faire-face par le Brief Cope. Dans les deux sociétés, une plus grande exposition au conflit et à ses violences est associée à des PTS plus importants et à plus de plaintes somatiques, les filles manifestant plus de détresse que les garçons. Un total de 6.8% des étudiants israéliens et 37.2% des étudiants palestiniens répondent à des critères du Post Traumatic Stress Disorder (PTSD). Dans les deux sociétés, mais de façon plus prononcée dans l'Autorité palestinienne, les adolescents rapportent des niveaux significatifs de troubles fonctionnels, principalement dans le domaine du fonctionnement scolaire. Les étudiants avec PTSD manifestent plus de plaintes somatiques, il en va de même pour les troubles fonctionnels. Les résultats montrent le sérieux impact psychologique d'un conflit violent et continuel sur les étudiants israéliens et palestiniens et signale le besoin de développer des interventions scolaires appropriées à leurs besoins en matière de santé mentale. [source]


    Mock as screen and optic

    CRITICAL QUARTERLY, Issue 3 2004
    Simon Jarvis
    As its unique approach to the question of generational differences, this essay takes the relationship looks at poetry and modernity; that is, what happens when a style [such as the mock heroic, or the poetically inflated] starts to feel its age, yet doesn't die; and how its readers cope with its resurrections. Moving nimbly from Nigel Slater to Alexander Pope and back, the essay abandons the usual and reduced conception of 'mock' - that it describes trivial happenings but in an elevated language - and instead looks for a better conception, suggesting instead that mock is ubiquitous, both in literature and the everyday, as a broad and all-pervasive style of thinking and feeling. [source]


    War, Livelihoods and Vulnerability in Sri Lanka

    DEVELOPMENT AND CHANGE, Issue 2 2004
    Benedikt Korf
    As the number of de-stabilized regions of warfare or post-war conditions worldwide continues to grow, this article investigates how civilians survive in the context of a civil war. It analyses livelihood strategies of farmers in the war-torn areas of Sri Lanka, using an analytical framework based on a revised form of DFID's sustainable rural livelihoods approach, placing particular attention on the institutional reproduction of household capital assets in the war economy. The author delineates a three pillar model of household livelihood strategies focusing on how households (1) cope with the increased level of risk and uncertainty; (2) adjust their economic and social household assets for economic survival; and (3) use their social and political assets as livelihood strategies. Empirical evidence comes from four case study villages in the east of Sri Lanka. Although the four case studies were very close together geographically, their livelihood outcomes differed considerably depending on the very specific local political geography. The role of social and political assets is essential: while social assets (extended family networks) were important to absorb migrants, political assets (alliances with power holders) were instrumental in enabling individuals, households or economic actors to stabilize or even expand their livelihood options and opportunities. The author concludes that civilians in conflict situations are not all victims (some may also be culprits in the political economy of warfare), and that war can be both a threat and an opportunity, often at the same time. [source]


    Truth and the Enigma of Knowability

    DIALECTICA, Issue 4 2007
    Bernhard Weiss
    Since its disc overy by Fitch, the paradox of knowability has been a thorn in the anti-realist's side. Recently both Dummett and Tennant have sought to relieve the anti-realist by restricting the applicability of the knowability principle , the principle that all truths are knowable , which has been viewed as both a cardinal doctrine of anti-realism and the assumption for reductio of Fitch's argument. In this paper it is argued that the paradox of knowability is a peculiarly acute manifestation of a syndrome affecting anti-realism, against which Dummett's and Tennant's manoeuvres are not finally efficacious. The anti-realist can only cope with the syndrome by being much clearer about her notion of knowability. In fact, she'll have to offer an account which relativises the notion of knowability both to the world at which knowability is assessed and to the content of the proposition to which it is applied. This is not, however, merely an ad hoc manoeuvre to counter the problematic syndrome; rather it is just what we should expect from the anti-realist's intuitive use of the notion. A preliminary investigation indicates that there is no way of providing a general, systematic explanation of such a notion of knowability and thus an inherent restriction on the principle of knowability , but one differing from those offered by either Dummett or Tennant , is developed. [source]


    Changing household responses to drought in Tharaka, Kenya: vulnerability, persistence and challenge

    DISASTERS, Issue 2 2008
    Thomas A. Smucker
    Drought is a recurring challenge to the livelihoods of those living in Tharaka District, Kenya, situated in the semi-arid zone to the east of Mount Kenya, from the lowest slopes of the mountain to the banks of the Tana River. This part of Kenya has been marginal to the economic and political life of Kenya from the colonial period until the present day. A study of more than 30 years of change in how people in Tharaka cope with drought reveals resilience in the face of major macro-level transformations, which include privatisation of landownership, population growth, political decentralisation, increased conflict over natural resources, different market conditions, and environmental shifts. However, the study also shows troubling signs of increased use of drought responses that are incompatible with long-term agrarian livelihoods. Government policy needs to address the challenge of drought under these new macro conditions if sustainable human development is to be achieved. [source]


    Social Capital, Collective Action, and Adaptation to Climate Change

    ECONOMIC GEOGRAPHY, Issue 4 2003
    W. Neil Adger
    Abstract: Future changes in climate pose significant challenges for society, not the least of which is how best to adapt to observed and potential future impacts of these changes to which the world is already committed. Adaptation is a dynamic social process: the ability of societies to adapt is determined, in part, by the ability to act collectively. This article reviews emerging perspectives on collective action and social capital and argues that insights from these areas inform the nature of adaptive capacity and normative prescriptions of policies of adaptation. Specifically, social capital is increasingly understood within economics to have public and private elements, both of which are based on trust, reputation, and reciprocal action. The public-good aspects of particular forms of social capital are pertinent elements of adaptive capacity in interacting with natural capital and in relation to the performance of institutions that cope with the risks of changes in climate. Case studies are presented of present-day collective action for coping with extremes in weather in coastal areas in Southeast Asia and of community-based coastal management in the Caribbean. These cases demonstrate the importance of social capital framing both the public and private institutions of resource management that build resilience in the face of the risks of changes in climate. These cases illustrate, by analogy, the nature of adaptation processes and collective action in adapting to future changes in climate. [source]


    Altered gene expression in the brain and ovaries of zebrafish (Danio Rerio) exposed to the aromatase inhibitor fadrozole: Microarray analysis and hypothesis generation,,

    ENVIRONMENTAL TOXICOLOGY & CHEMISTRY, Issue 8 2009
    Daniel L. Villeneuve
    Abstract As part of a research effort examining system-wide responses of the hypothalamic-pituitary-gonadal (HPG) axis in fish to endocrine-active chemicals (EACs) with different modes of action, zebrafish (Danio rerio) were exposed to 25 or 100 ,g/L of the aromatase inhibitor fadrozole for 24, 48, or 96 h. Global transcriptional response in brain and ovarian tissue of fish exposed to 25 ,g/L of fadrozole was compared to that in control fish using a commercially available, 22,000-gene oligonucleotide microarray. Transcripts altered in brain were functionally linked to differentiation, development, DNA replication, and cell cycle. Additionally, multiple genes associated with the one-carbon pool by folate pathway (KEGG 00670) were significantly up-regulated. Transcripts altered in ovary were functionally linked to cell-cell adhesion, extracellular matrix, vasculogenesis, and development. Promoter motif analysis identified GATA-binding factor 2, Ikaros 2, alcohol dehydrogenase gene regulator 1, myoblast-determining factor, and several heat shock factors as being associated with coexpressed gene clusters that were differentially expressed following exposure to fadrozole. Based on the transcriptional changes observed, it was hypothesized that fadrozole elicits neurodegenerative stress in brain tissue and that fish cope with this stress through proliferation of radial glial cells. Additionally, it was hypothesized that changes of gene expression in the ovary of fadrozole-exposed zebrafish reflect disruption of oocyte maturation and ovulation because of impaired vitellogenesis. These hypotheses and others derived from the microarray results provide a foundation for future studies aimed at understanding responses of the HPG axis to EACs and other chemical stressors. [source]


    CONTRASTING PLANT PHYSIOLOGICAL ADAPTATION TO CLIMATE IN THE NATIVE AND INTRODUCED RANGE OF HYPERICUM PERFORATUM

    EVOLUTION, Issue 8 2007
    John L. Maron
    How introduced plants, which may be locally adapted to specific climatic conditions in their native range, cope with the new abiotic conditions that they encounter as exotics is not well understood. In particular, it is unclear what role plasticity versus adaptive evolution plays in enabling exotics to persist under new environmental circumstances in the introduced range. We determined the extent to which native and introduced populations of St. John's Wort (Hypericum perforatum) are genetically differentiated with respect to leaf-level morphological and physiological traits that allow plants to tolerate different climatic conditions. In common gardens in Washington and Spain, and in a greenhouse, we examined clinal variation in percent leaf nitrogen and carbon, leaf ,13C values (as an integrative measure of water use efficiency), specific leaf area (SLA), root and shoot biomass, root/shoot ratio, total leaf area, and leaf area ratio (LAR). As well, we determined whether native European H. perforatum experienced directional selection on leaf-level traits in the introduced range and we compared, across gardens, levels of plasticity in these traits. In field gardens in both Washington and Spain, native populations formed latitudinal clines in percent leaf N. In the greenhouse, native populations formed latitudinal clines in root and shoot biomass and total leaf area, and in the Washington garden only, native populations also exhibited latitudinal clines in percent leaf C and leaf ,13C. Traits that failed to show consistent latitudinal clines instead exhibited significant phenotypic plasticity. Introduced St. John's Wort populations also formed significant or marginally significant latitudinal clines in percent leaf N in Washington and Spain, percent leaf C in Washington, and in root biomass and total leaf area in the greenhouse. In the Washington common garden, there was strong directional selection among European populations for higher percent leaf N and leaf ,13C, but no selection on any other measured trait. The presence of convergent, genetically based latitudinal clines between native and introduced H. perforatum, together with previously published molecular data, suggest that native and exotic genotypes have independently adapted to a broad-scale variation in climate that varies with latitude. [source]


    Experimental and steady-state analysis of the GAL regulatory system in Kluyveromyces lactis

    FEBS JOURNAL, Issue 14 2010
    Venkat R. Pannala
    The galactose uptake mechanism in yeast is a well-studied regulatory network. The regulatory players in the galactose regulatory mechanism (GAL system) are conserved in Saccharomyces cerevisiae and Kluyveromyces lactis, but the molecular mechanisms that occur as a result of the molecular interactions between them are different. The key differences in the GAL system of K. lactis relative to that of S. cerevisiae are: (a) the autoregulation of KlGAL4; (b) the dual role of KlGal1p as a metabolizing enzyme as well as a galactose-sensing protein; (c) the shuttling of KlGal1p between nucleus and cytoplasm; and (d) the nuclear confinement of KlGal80p. A steady-state model was used to elucidate the roles of these molecular mechanisms in the transcriptional response of the GAL system. The steady-state results were validated experimentally using measurements of ,-galactosidase to represent the expression for genes having two binding sites. The results showed that the autoregulation of the synthesis of activator KlGal4p is responsible for the leaky expression of GAL genes, even at high glucose concentrations. Furthermore, GAL gene expression in K. lactis shows low expression levels because of the limiting function of the bifunctional protein KlGal1p towards the induction process in order to cope with the need for the metabolism of lactose/galactose. The steady-state model of the GAL system of K. lactis provides an opportunity to compare with the design prevailing in S. cerevisiae. The comparison indicates that the existence of a protein, Gal3p, dedicated to the sensing of galactose in S. cerevisiae as a result of genome duplication has resulted in a system which metabolizes galactose efficiently. [source]


    Sulfur assimilation and glutathione metabolism under cadmium stress in yeast, protists and plants

    FEMS MICROBIOLOGY REVIEWS, Issue 4 2005
    David Mendoza-Cózatl
    Abstract Glutathione (,-glu-cys-gly; GSH) is usually present at high concentrations in most living cells, being the major reservoir of non-protein reduced sulfur. Because of its unique redox and nucleophilic properties, GSH serves in bio-reductive reactions as an important line of defense against reactive oxygen species, xenobiotics and heavy metals. GSH is synthesized from its constituent amino acids by two ATP-dependent reactions catalyzed by ,-glutamylcysteine synthetase and glutathione synthetase. In yeast, these enzymes are found in the cytosol, whereas in plants they are located in the cytosol and chloroplast. In protists, their location is not well established. In turn, the sulfur assimilation pathway, which leads to cysteine biosynthesis, involves high and low affinity sulfate transporters, and the enzymes ATP sulfurylase, APS kinase, PAPS reductase or APS reductase, sulfite reductase, serine acetyl transferase, O -acetylserine/O -acetylhomoserine sulfhydrylase and, in some organisms, also cystathionine ,-synthase and cystathionine ,-lyase. The biochemical and genetic regulation of these pathways is affected by oxidative stress, sulfur deficiency and heavy metal exposure. Cells cope with heavy metal stress using different mechanisms, such as complexation and compartmentation. One of these mechanisms in some yeast, plants and protists is the enhanced synthesis of the heavy metal-chelating molecules GSH and phytochelatins, which are formed from GSH by phytochelatin synthase (PCS) in a heavy metal-dependent reaction; Cd2+ is the most potent activator of PCS. In this work, we review the biochemical and genetic mechanisms involved in the regulation of sulfate assimilation-reduction and GSH metabolism when yeast, plants and protists are challenged by Cd2+. [source]


    Ankerung im Untertagebau , Entwicklungen in Theorie und Praxis

    GEOMECHANICS AND TUNNELLING, Issue 5 2008
    Stefan Kainrath-Reumayer Dipl.-Ing.
    Die systematische Ankerung des Gebirges stellt ein wesentliches Verfahren zur Stabilisierung unterirdischer Hohlraumbauten dar. Die geschichtliche Entwicklung verschiedener Ankersysteme wird kurz vorgestellt und Unterteilungsmöglichkeiten werden aufgezeigt. Unterschiedliche Ansätze der Systemankerungen in analytischen und numerischen Berechnungen werden mit der diskreten Modellierung des Gesamtssystems in numerischen Berechnungen mit FLAC3D verglichen. Der Einfluss von Systemankerungen auf das Systemverhalten ist von einer Reihe von Randbedingungen abhängig, der Erfolg der Anwendung oftmals von den verwendeten Ankersystemen. Extreme Spannungszustände im Gebirge stellen hohe Anforderungen an die Methodik der Gebirgsankerung in Untertagebauwerken, die mit den herkömmlichen Ankerungssystemen nur eher unzufriedenstellend zu bewältigen sind. In Abhängigkeit von den Eigenschaften des Gebirges ist unter solch hohen, die Festigkeit des intakten Gebirges meist bereits überschreitenden Spannungszuständen mit großen Verschiebungen, Stabilitätsproblemen sowie Bergschlagphänomenen zu rechnen. Um diesen Anforderungen bestmöglich gerecht zu werden, wird ein neuartiger, energieabsorbierender Ankertyp "Roofex" vorgestellt, der sowohl unter langsam kriechenden, statischen, wie auch abrupten, dynamischen Beanspruchungen einen kontrollierbaren und konstanten Widerstand entlang eines definierten Gleitwegs aufweist. Rock bolting in subsurface constructions , developments in theory and praxis The systematic bolting of rock is a key support element in NATM tunnelling. A short review on the historical development and methods of classification is presented. Different methods of implementation in analytical and numerical calculations are compared to the discrete modelling of the system via FLAC 3D. The influence of the systematic rock bolting to the system behaviour is dependent on many boundary conditions, the success often depends on the used rock bolting techniques. High rock mass stress conditions in underground excavations are serious challenges for rock bolting systems, where conventional bolting systems can only cope with in an rather unsatisfactory way. Depending on the rock mass conditions, high stresses, which mostly exceed already the intact rock mass strength, will lead to serious stability problems, high deformation rates and rockburst phenomena. To provide the mining and tunnelling industry with a rock reinforcement fixture that is better suited to mining with high stress conditions, Atlas Copco GDE designed a new, energy absorbing rock bolt "Roofex" that can accommodate both very large displacements (static yielding) and high energy release (dynamic rupture) in the rock mass by offering an accurate pre-set deformation behaviour. [source]


    Juggling Burdens of Representation: Black, Red, Gold and Turquoise

    GERMAN LIFE AND LETTERS, Issue 4 2006
    Tom Cheesman
    ABSTRACT This essay suggests an alternative to the usual practice of categorising migrant writers by generation, in order to counter the teleological tendency in some recent commentaries on German-Turkish writing which celebrate the youngest writers as the most ,advanced'. Instead I put forward the idea that different writers (and writers at different stages in their careers) adopt different strategies in order to cope with the ,burden of representation' which is imposed on them as migrant/minority artists by the public. I survey German-Turkish novelists, outlining a tentative typology of such strategies. ,Axial writing' (directly thematising migrant experience) is the commonest, and has many sub-varieties, but the alternatives are just as interesting. [source]


    Predictors of the International HIV,AIDS INGO Network Over Time

    HUMAN COMMUNICATION RESEARCH, Issue 4 2005
    Michelle Shumate
    The HIV,AIDS epidemic is one of the most challenging and significant health crises facing the world today. In order to cope with its complexities, the United Nations and World Health Organization have increasingly relied upon the resources offered by networks of HIV,AIDS nongovernmental organizations (NGOs). The research reported here uses evolutionary theory to predict the patterns of alliances and collaborations within the HIV,AIDS International Nongovernmental Organizations (INGO) network. The hypotheses are tested using 8 years of data from the Yearbook of International Organizations. The results showed that geographic proximity and common ties with intergovernmental organizations (IGOs) predict the pattern of alliances among HIV,AIDS INGOs. The best predictor of such alliances, however, is past relationships among these organizations. [source]


    Psychological capital: A positive resource for combating employee stress and turnover

    HUMAN RESOURCE MANAGEMENT, Issue 5 2009
    James B. Avey
    Abstract Workplace stress is a growing concern for human resource managers. Although considerable scholarly and practical attention has been devoted to stress management over the years, the time has come for new perspectives and research. Drawing from the emerging field of positive organizational behavior, this study offers research findings with implications for combating occupational stress. Specifically, data from a large sample of working adults across a variety of industries suggest that psychological capital (the positive resources of efficacy, hope, optimism, and resilience) may be key to better understanding the variation in perceived symptoms of stress, as well as intentions to quit and job search behaviors. The article concludes with practical strategies aimed at leveraging and developing employees' psychological capital to help them better cope with workplace stress. © 2009 Wiley Periodicals, Inc. [source]