Congenital Infection (congenital + infection)

Distribution by Scientific Domains


Selected Abstracts


Cytomegalovirus Infection: Perinatal Implications

JOURNAL OF OBSTETRIC, GYNECOLOGIC & NEONATAL NURSING, Issue 1 2002
Elizabeth G. Damato RN
Cytomegalovirus (CMV), a member of the herpes virus family, is the most common cause of congenital infection in humans, affecting 0.5,3% of all newborns worldwide. Congenital cytomegalovirus infection is the leading infectious cause of deafness, learning disabilities, and mental retardation in children. The high prevalence of cytomegalovirus in the general population, unpredictability of transmission, and asymptomatic nature of the disease in otherwise healthy women challenge prevention and treatment efforts. [source]


Case of congenital infection with Candida glabrata in one infant in a set of twins

PEDIATRICS INTERNATIONAL, Issue 4 2002
Hirokazu Arai
No abstract is available for this article. [source]


HCMV seroprevalence and associated risk factors in pregnant women, Havana City, 2007 to 2008

PRENATAL DIAGNOSIS, Issue 9 2010
C. B. Correa
Abstract Objective To prenatally identify pregnant women at risk of developing congenital infection due to human cytomegalovirus (HCMV). Methods One thousand one hundred and thirty-one pregnant women from three municipalities from Havana City were serologically screened for HCMV infection (IgM/IgG, IgG avidity) from January 2007 to January 2008. Demographical, epidemiological, and clinical variables were correlated to serologic status to identify predictors of seroconversion in pregnancy. Results The majority of women were seropositive to HCMV (92.6%); 27 women (2.4%) developed HCMV active infection during pregnancy, defined by the detection of IgG+ and IgM+ (7 women), IgM+ and IgG, (2 women), and IgG seroconversion (18 women). Susceptibility of active HCMV infection during pregnancy was associated with maternal age < 20 years and nulligravidity. Primary infection was detected in 20 pregnant women (1.8%), whereas 7 patients (0.6%) had active non-primary infection. Conclusion Although pregnant women in Cuba have high seroprevalence rates for HCMV, those younger than 20 years and nulligravidae are at risk of acquiring infection during pregnancy. Copyright © 2010 John Wiley & Sons, Ltd. [source]


Congenital systemic Langerhans cell histiocytosis presenting as hydrops fetalis

ACTA PAEDIATRICA, Issue 12 2005
Cheuk H Lee
Abstract Congenital Langerhans cell histiocytosis (LCH) encompasses a wide spectrum of disease involvement and severity. Congenital "self-healing" cutaneous LCH represents one end of the spectrum, whereas the case we encountered represents the other extreme. A rare case of congenital LCH with severe multiorgan involvement presenting as hydrops fetalis is described in this report. Hydrops fetalis has not previously been associated with congenital LCH. The overall clinical features of this infant closely mimicked those of disseminated congenital infection, and he ran a fulminant and rapidly fatal course. Conclusion: A high index of suspicion is required to diagnose congenital LCH in the early neonatal period. Hydrops fetalis is an ominous sign and probably reflects severe systemic disease compromising the well-being of the fetus. [source]