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Completion
Kinds of Completion Terms modified by Completion Selected AbstractsUse of mouthguards by basketball players in Victoria, AustraliaDENTAL TRAUMATOLOGY, Issue 4 2003Helen Cornwell Abstract ,,,Basketball is a popular sport in Australia. Although orofacial injuries are common, mouthguard (MG) wear in basketball appears to be low. The purposes of this study were: to measure mouthguard wear by basketball players before and after a promotional intervention; to assess players' knowledge of the value of mouthguards for prevention of injury; and to describe their experience of orofacial injury. Two questionnaires (baseline and follow-up) were administered to a convenience sample of 496 basketball players in Victoria, Australia. Players recruited were youths (12,15-year olds, n = 208) and adults (18 years and over, n = 288), from all basketball levels (social to elite). Completion of the baseline questionnaire was followed immediately by an intervention comprising written and verbal information, a mouthguard blank and instructions on mouthguard construction. The follow-up questionnaire was mailed to all respondents 10,12 weeks later; 135 youths (65%) and 157 adults (54%) completed this. Mouthguard wear at baseline was low but was more frequent at games (62%) than at training (25%). Despite 90% of players acknowledging the protective value of a mouthguard, wear by youths did not increase following the intervention, and wear by adults increased by only 14% for training and 10% at games. Previous orofacial injury was recorded at baseline by 23% of players, but few had requested compensation from Basketball Australia (youths, 17%; adults, 30%). Two predictor variables were statistically identified as related to mouthguard wear: previous orofacial injury and age group. Mouthguard wear was significantly more frequent amongst players with previous injury; such players were 2.76 times more likely to be wearers than those without previous injury. Youths were 2.31 times more likely to wear mouthguards than adults. Only 34 players (12% of respondents at follow-up) had a mouthguard constructed from the blank provided. Although youth and adult groups differed, the overall extent of mouthguard use was disappointingly low. Despite wide recognition of mouthguard value, the intervention had little effect on promoting their use. [source] Initiation of limb regeneration: The critical steps for regenerative capacityDEVELOPMENT GROWTH & DIFFERENTIATION, Issue 1 2008Hitoshi Yokoyama While urodele amphibians (newts and salamanders) can regenerate limbs as adults, other tetrapods (reptiles, birds and mammals) cannot and just undergo wound healing. In adult mammals such as mice and humans, the wound heals and a scar is formed after injury, while wound healing is completed without scarring in an embryonic mouse. Completion of regeneration and wound healing takes a long time in regenerative and non-regenerative limbs, respectively. However, it is the early steps that are critical for determining the extent of regenerative response after limb amputation, ranging from wound healing with scar formation, scar-free wound healing, hypomorphic limb regeneration to complete limb regeneration. In addition to the accumulation of information on gene expression during limb regeneration, functional analysis of signaling molecules has recently shown important roles of fibroblast growth factor (FGF), Wnt/,-catenin and bone morphogenic protein (BMP)/Msx signaling. Here, the routine steps of wound healing/limb regeneration and signaling molecules specifically involved in limb regeneration are summarized. Regeneration of embryonic mouse digit tips and anuran amphibian (Xenopus) limbs shows intermediate regenerative responses between the two extremes, those of adult mammals (least regenerative) and urodele amphibians (more regenerative), providing a range of models to study the various abilities of limbs to regenerate. [source] ESCI award lecture: from a little mouse to rationale medicine for bone lossEUROPEAN JOURNAL OF CLINICAL INVESTIGATION, Issue 10 2009A. Leibbrandt Abstract Completion of the human genome is one of the many significant milestones in the new era of systems biology. The current phase of genomic studies is focused upon parsing this new found genetic data with respect to scientific interest, and economic and health impact applications. As the sequences are now available and whole genome single nucleotide polymorphism maps for multiple human diseases will be available with the advent of modern genomics, the big challenge is to determine the function of these genes in the context of the entire organism. The emphasis is therefore on functional genomic analysis that represents the new front-line and limiting factor for realizing potential benefits of genome-based science. Defined gene targeting has been proven to be particularly useful as loss of expression mutants can reveal essential functions of molecules and the pathogenesis of disease. Using gene-targeted mice, my group has over the years identified genes that control heart and lung functions [1,5]; apoptosis [6,9]; lymphocyte activation [10,14]; cancer [15,17]; pain [18]; diabetes [19]; fertility [20] or wound healing [21]. In this study, I would like to review our work on RANKL in more detail. [source] Beyond the Customs Union: The European Community's Quest for Deepening, Widening and Completion, 1969,75 , Edited by J. Van Der HarstJCMS: JOURNAL OF COMMON MARKET STUDIES, Issue 4 2008LUIS SIMON No abstract is available for this article. [source] Completion of crystal structures from powder data: the use of the coordination polyhedraJOURNAL OF APPLIED CRYSTALLOGRAPHY, Issue 6 2000Angela Altomare Direct methods applied to powder diffraction data often provide well located heavy atoms and unreliable light-atom positions. The completion of the crystal structure is then not always straightforward and may require a considerable amount of user intervention. The heavy-atom connectivity provided by the trial solution may be used to guess the nature of the coordination polyhedra. A Monte Carlo procedure is described which, in the absence of a well defined structural model, is able to locate the light atoms correctly under the restraints of the experimental heavy-atom connectivity model. The correctness of the final model is assessed by criteria based on the agreement between the whole experimental diffraction pattern and the calculated one. The procedure requires little CPU computing time and has been implemented as a routine of EXPO [Altomare et al. (1999). J. Appl. Cryst.32, 339,340]. The method has proved to be sufficiently robust against the distortion of the coordination polyhedra and has been successfully applied to some test structures. [source] The Sentence Completion and Three Wishes tasks: windows into the inner lives of people with intellectual disabilitiesJOURNAL OF INTELLECTUAL DISABILITY RESEARCH, Issue 8 2007E. Dykens Abstract Background Measuring the self-perceptions, thoughts, hopes and inner lives of persons with intellectual disabilities (ID) has long been a research challenge. Unlike objective or projective tests, semi-projective tasks may provide persons with ID with just enough structure or cues to convey their self-perceptions in a spontaneous and unbiased manner. Methods Sentence Completion and Three Wishes tasks were individually administered to 128 persons with ID aged 5,50 years (mean = 18.75 years). Participants had Prader,Willi, Williams or Down syndromes. Content analyses resulted in 19 codes that were used to reliably score both tasks by independent raters who achieved excellent levels of inter-rater agreement. Participants also received IQ testing, and their parents or care providers completed the Child Behavior Checklist (CBCL). Results Frequent themes across both tasks included activities, positive affect, desired objects, and relationships with family and pets. No gender or IQ effects were found, and just a few codes showed modest age effects. Several responses, including dating, friends, food, and positive or negative self-appraisals, were significantly related to either syndrome status or CBCL maladaptive behaviour. Conclusions Although not widely used, the Sentence Completion and Three Wishes tasks are useful semi-projective techniques for garnering otherwise hard-to-access self-perceptions and associations of people with ID. Implications are discussed for practice and research. [source] CLINICAL SCHOLARSHIP: Systematic Review of Educational Interventions for Improving Advance Directive CompletionJOURNAL OF NURSING SCHOLARSHIP, Issue 3 2010Christine R. Durbin RN Abstract Purpose: To systematically analyze evidence about the outcome and percent of newly completed ADs, focusing on the effectiveness of (a) types of educational interventions versus controls and (b) one educational intervention over another. Design: Systematic review of literature based on Cochrane review criteria. Methods: Twelve randomized and four nonrandomized studies were selected from the nursing, medical, and social work literature that met the following criteria: described educational interventions, provided information to calculate the percent of newly completed ADs as an outcome, and published between 1991 and 2009. The review focused primarily on randomized studies. Reviewers calculated the percent of newly completed ADs by determining the number of subjects per group without an AD at baseline and the percentage of those who then completed one by the end of the studies. Findings: Findings were inconsistent regarding all types of educational interventions studied versus controls. Sufficient evidence exists to conclude that combined written and verbal educational interventions were more effective than single written interventions in increasing the percent of newly completed ADs in adult clinic outpatients and hospitalized elderly. Conclusions: Calculating the percent of newly completed ADs was successful in allowing for study result comparisons. Overall, the evidence base regarding the effectiveness of single or combined educational interventions in increasing AD completion is weak. Randomized studies with diverse samples should be conducted against controls before more studies comparing interventions are undertaken. Clinical Relevance: This article provides nurses with a summary of research related to educational interventions and AD completion and identifies where future study is needed. [source] Treatment Completion in a Brief Motivational Intervention in the Emergency Department: The Effect of Multiple Interventions and Therapists' BehaviorALCOHOLISM, Issue 2007Janette Baird Background:, The aim of this study was to identify therapist behaviors during a brief motivational intervention (BMI) given to injured emergency department patients that predicted participant return for a second BMI session and 12-month alcohol-related outcomes. Method:, This was a secondary data analysis of a randomized controlled trial (n = 539) previously demonstrating that random assignment to a BMI and booster session resulted in a significant reduction of 12-month postintervention alcohol-related injuries and negative consequences relative to standard care. Results:, Participants who actually received 2 BMI sessions had significantly less alcohol-related negative consequences than those who received only 1 BMI session. Therapists who reported a higher focus on emotional support and low focus on participant drinking behaviors during the initial BMI session were more likely to have assigned participants return for the second BMI session. Conclusion:, The results of these secondary analyses show that compliance with a 2-session therapeutic intervention (BIB) predicted fewer negative alcohol-related consequences, and that therapists' supportive emotional emphasis during the first BMI session was important in predicting participants returning for the second MI session. [source] Influence of Water Temperature on Morphological Deformities in Cultured Larvae of Japanese Eel, Anguilla japonica, at Completion of Yolk ResorptionJOURNAL OF THE WORLD AQUACULTURE SOCIETY, Issue 6 2008Tadahide Kurokawa The occurrence of morphological deformities under different rearing water temperatures (18, 20, 22, 24, 26, 28, and 30 C) was examined in Japanese eel larvae. The rates of hatching and survival until yolk resorption at 22,26 C were higher than those at other water temperatures. Fertilized eggs never hatched at 18 and 30 C. The rates of occurrence of abnormal larvae reared at the water temperatures 24,28 C were lower than those at 20 or 22 C. Pericardial edema and lower jaw deformities occurred most frequently at lower temperatures (20 and 22 C). In contrast, the incubation temperature did not significantly affect the relative frequency of some neurocranial deformities and of spinal curvature. These results imply that the optimal temperatures for rearing Japanese eel eggs and embryos are 24,26 C from the viewpoints of survival and deformity. [source] Fluid resuscitation from severe hemorrhagic shock using diaspirin cross-linked hemoglobin fails to improve pancreatic and renal perfusionACTA ANAESTHESIOLOGICA SCANDINAVICA, Issue 10 2004A. Pape Background:, Fluid resuscitation from hemorrhagic shock is intended to abolish microcirculatory disorders and to restore adequate tissue oxygenation. Diaspirin cross-linked hemoglobin (DCLHb) is a hemoglobin-based oxygen carrier (HBOC) with vasoconstrictive properties. Therefore, fluid resuscitation from severe hemorrhagic shock using DCLHb was expected to improve perfusion pressure and tissue perfusion of kidneys and pancreas. Methods:, In 20 anesthetized domestic pigs with an experimentally induced coronary stenosis, shock (mean arterial pressure 45 mmHg) was induced by controlled withdrawal of blood and maintained for 60 min. Fluid resuscitation (replacement of the plasma volume withdrawn during hemorrhage) was performed with either 10% DCLHb (DCLHb group, n = 10) or 8% human serum albumin (HSA) oncotically matched to DCLHb (HSA group, n = 10). Completion of resuscitation was followed by a 60-min observation period. Regional blood flow to the kidneys and the pancreas was measured by use of the radioactive microspheres method at baseline, after shock and 60 min after fluid resuscitation. Results:, All animals (10/10) resuscitated with DCLHb survived the 60-min observation period, while 5/10 control animals died within 20 min due to persisting subendocardial ischemia. In contrast to HSA survivors, pancreas and kidneys of DCLHb-treated animals revealed lower total and regional organ perfusion and regional oxygen delivery. Renal and pancreatic blood flow heterogeneity was higher in the DCLHb group. Conclusion:, DCLHb-induced vasoconstriction afforded superior myocardial perfusion, but impaired regional perfusion of the kidneys and the pancreas. [source] Describing clinical teachers' characteristics and behaviours using critical incidents and repertory gridsMEDICAL EDUCATION, Issue 7 2006Praminthra Chitsabesan Context, Completion of a rating questionnaire is the method used most frequently to evaluate a teacher's performance. Questionnaires that largely assess ,high-inference' teaching characteristics, such as ,enthusiasm' and ,friendliness', require the observer to make a judgement about the teacher but do not describe what the teacher actually did and so have limited use in providing feedback. Measures of ,low-inference' teaching behaviours (i.e. those that are concrete and observable), such as frequency, amount or types of verbal interaction, do not demonstrate how these are linked to good teaching. Objectives, To describe high-inference teacher characteristics and define the associated low-inference behaviours. Methods, A purposive sample of consultants, postgraduate and undergraduate students, nurse lecture practitioners and patients were selected for semistructured interviews using repertory grids and critical incidents to elicit preferred characteristics and behaviours of clinical teachers. Interviews were audiotaped, transcribed and then content-analysed using a framework to pair teachers' characteristics and their behaviours. Results, We identified a variety of preferred high-inference characteristics and their associated observable and recordable low-inference behaviours. Discussion, We carried out a study that included all participants in clinical teaching and found that participants differed in their preferred characteristics and behaviours. It is important for future research to look at behaviours interdependently, rather than alone, and to take into account the evidence that participants tend to infer characteristics rather than think in terms of behaviours. This information will be used to inform the development of a formative tool for evaluating clinical teaching. [source] The SUN41 and SUN42 genes are essential for cell separation in Candida albicansMOLECULAR MICROBIOLOGY, Issue 5 2007Arnaud Firon Summary Completion of the yeast cell cycle involves extensive remodelling of the cell wall upon separation of mother and daughter cells. We have studied two members of the ascomycete-specific SUN gene family in Candida albicans. Inactivation of SUN41 yields defects in cell separation and hyphal elongation while inactivation of SUN42 results in minor phenotypic alterations. Simultaneous inactivation of SUN41 and SUN42 is synthetically lethal due to lysis of mother cells after septation. Electronic microscopy reveals cell wall defects mainly localized in the region surrounding the septa. This phenotype is osmoremediable and the conditional double mutants show increased sensitivity to cell wall or cell membrane perturbing agents. The essential function shared by Sun41p and Sun42p is conserved among yeasts because UTH1, a Saccharomyces cerevisiae SUN gene, suppresses the lethality of SUN41 and SUN42 conditional mutants. Investigation of functional genomic data obtained in S. cerevisiae reveals links between members of the SUN gene family and the RAM pathway regulating cell wall-degrading enzymes specifically involved during cell separation. Thus, the main function of ascomycetous Sun proteins appears linked to cell wall remodelling, with a probable role in counter-balancing cell wall degradation to avoid cell lysis upon cell separation. [source] Using Success Courses for Promoting Persistance and CompletionNEW DIRECTIONS FOR COMMUNITY COLLEGES, Issue 112 2000Martina Stovall Minority students often face greater challenges than their white peers in becoming integrated into the college environment. Recent research suggests that participation in a student success course could be especially beneficial for minority students who attend predominantly white community colleges. This chapter presents a model for designing and implementing a community college student success course. [source] New and Improved FHMPP Program Nears CompletionNURSING FOR WOMENS HEALTH, Issue 1 2003Shelagh Roberts No abstract is available for this article. [source] Mothers' Pap Screening and STD History Associated With Daughters' Uptake, Completion of HPV VaccinePERSPECTIVES ON SEXUAL AND REPRODUCTIVE HEALTH, Issue 3 2009Article first published online: 3 SEP 200 No abstract is available for this article. [source] Total Synthesis of Spirastrellolide,F Methyl Ester,Part,2: Macrocyclization and Completion of the Synthesis,ANGEWANDTE CHEMIE, Issue 52 2009Stefan Benson Dipl.-Chem. Wunder der See: Die kompakte und hoch konvergente Totalsynthese des Methylesters des marinen Makrolids Spirastrellolid,F (siehe Bild) wurde abgeschlossen. Dabei wurden die nördlichen und südlichen ,Hemisphären" in nur zwei Stufen ohne zwischengeschaltete Schutzgruppenmanipulationen zusammengefügt (Suzuki-Kupplung, Yamaguchi-Lactonisierung). [source] Things to Do Today . . . : A Daily Diary Study on Task Completion at WorkAPPLIED PSYCHOLOGY, Issue 2 2010Brigitte J.C. Claessens Relatively little is known about how goals in complex jobs are translated into action and how they are completed in real life settings. This study addressed the question to what extent planned work may actually be completed on a daily basis. The completion of daily work goals was studied in a sample of 878 tasks identified by 29 R&D engineers with the help of a daily diary. Multilevel analysis was used to analyse the joint effect of task attributes, perceived job characteristics, and personality attributes on the completion of planned work goals. At the level of task attributes, we found that priority, urgency, and lower importance were related to task completion, and at the individual level, conscientiousness, emotional stability, and time management training. Task completion was not related to task attractiveness, workload, job autonomy, planning, or perceived control of time. On connaît relativement peu de choses sur la manière dont les objectifs dans des tâches complexes sont traduites en action et sur la manière dont elles sont accomplies dans le cadre de la vie quotidienne. Cette étude a abordé la question de savoir dans quelle mesure les travaux prévus peuvent être effectivement achevés dans la vie quotidienne. Pour ce faire, un échantillon de 878 tâches a été identifié par 29 ingénieurs R&D à l'aide d'un journal quotidien. Une analyse multi niveau a été réalisée pour étudier l'effet conjoint des caractéristiques de la tâche et des caractéristiques de la personnalité sur l'accomplissement des objectifs d'un travail planifié. Au niveau des caractéristiques de la tâche, nous trouvons que l'accomplissement de la tâche est liéà la priorité, l'urgence et une importance basse et au niveau individuel à la conscience, la stabilitéémotionnelle et à la gestion du temps. L'accomplissement de la tâche n'est pas liéà son attrait, à la charge de travail, à l'autonomie au travail ou au contrôle du temps perçu. [source] Plasmodium,mosquito interactions: a tale of dangerous liaisonsCELLULAR MICROBIOLOGY, Issue 11 2005Carolina Barillas-Mury Summary To complete their life cycle, Plasmodium parasites must survive the environment in the insect host, cross multiple barriers including epithelial layers, and avoid destruction by the mosquito immune system. Completion of the Anopheles gambiae and Plasmodium falciparum genomes has opened the opportunity to apply high throughput methods to the analysis of gene function. The burst of information generated by these approaches and the use of molecular markers to investigate the cell biology of these interactions is broadening our understanding of this complex system. This review discusses our current understanding of the critical interactions that take place during the journey of Plasmodium through the mosquito host, with special emphasis on the responses of midgut epithelial cells to parasite invasion. [source] Enantioselective Total Synthesis of Brevetoxin A: Convergent Coupling Strategy and CompletionCHEMISTRY - A EUROPEAN JOURNAL, Issue 36 2009Michael Abstract A highly convergent, enantioselective total synthesis of brevetoxin A is reported. The development of a [X+2+X] Horner,Wadsworth,Emmons/cyclodehydration/reductive etherification convergent coupling strategy allowed a unified approach to the synthesis of two advanced tetracyclic fragments from four cyclic ether subunits. The Horner,Wittig coupling of the two tetracyclic fragments provided substrates that were explored for reductive etherification, the success of which delivered a late-stage tetraol intermediate. The tetraol was converted to the natural product through an expeditious selective oxidative process followed by methylenation. [source] Personal disciplinary history and views of physical punishment: implications for training mandated reportersCHILD ABUSE REVIEW, Issue 4 2005Cheryl Bluestone Abstract Many nations, including the US, Australia, and Canada, have developed legislation at the local or national level to require selected professionals to report all cases of suspected child abuse as part of the system to prevent serious injuries or fatalities. In many states of the US, including New York, child service professionals must take a training course to ensure that they are aware of their legal obligations as mandated reporters. Completion of the course is often a prerequisite to obtain certification to practise in one's field. Despite this rudimentary training, many cases of suspected abuse are not reported. Moreover, many child abuse professionals experience confusion and emotional distress in dealing with the reporting process (Buckley, 2000). While training that considers potential influences on reporting can be effective in addressing some of these issues (Hawkins et al., 2001), there are few studies of the effectiveness of current training curricula (Alvarez et al., 2004). This preliminary investigation was conducted with 80 nursing and education students, an identified group of prospective mandated reporters. We examined the potential influence of childhood disciplinary experiences and their appraisal as these factors may relate to views of discipline and abuse. The findings revealed that history of childhood experiences with discipline, in conjunction with appraisals of rejection, accounted for a small, but significant amount of the variance in students' current beliefs about appropriate discipline. The findings are considered in the context of findings about training for professionals who are in a position to report suspected child abuse. When considered with that literature, these findings suggest that disciplinary history should be considered in the context of evaluations of the effectiveness of training curricula for mandated reporters. Copyright © 2005 John Wiley & Sons, Ltd. [source] The Effects of the 1999 Turkish Earthquake on Young Children: Analyzing Traumatized Children's Completion of Short StoriesCHILD DEVELOPMENT, Issue 4 2010Elif Celebi Oncu The purpose of this exploratory study was to determine whether projective techniques could identify long-term consequences among children stemming from exposure to a traumatic event. The first group of children (n = 53; 26 female, 27 male) experienced 2 major earthquakes at age 7, 3 months apart, in Turkey, while a similarly matched control group (n = 50; 25 female, 25 male) did not. Both groups of children (current age: 9) completed a series of short stories related to disastrous events. Results indicated that the traumatized group evinced a range of trauma-related symptoms 2 years after experiencing the earthquakes. [source] Development of Three-Dimensional Object Completion in InfancyCHILD DEVELOPMENT, Issue 5 2008Kasey C. Soska Three-dimensional (3D) object completion was investigated by habituating 4- and 6-month-old infants (n= 24 total) with a computer-generated wedge stimulus that pivoted 15°, providing only a limited view. Two displays, rotating 360°, were then shown: a complete, solid volume and an incomplete, hollow form composed only of the sides seen during habituation. There were no reliable preferences for either test display by 4-month-olds. At 6 months, infants showed a reliable novelty preference for the incomplete test display. Infants in a control group (n= 24) not habituated to the limited-view wedge preferred neither test display. By 6 months, infants may represent simple objects as complete in 3D space despite a limited perspective. Possible mechanisms of development of 3D object completion are discussed. [source] Perceptual Completion in Newborn Human InfantsCHILD DEVELOPMENT, Issue 6 2006Eloisa Valenza Despite decades of studies of human infants, a still open question concerns the role of visual experience in the development of the ability to perceive complete shapes over partial occlusion. Previous studies show that newborns fail to manifest this ability, either because they lack the visual experience required for perceptual completion or because they fail to detect the pattern of motion. To distinguish these possibilities, newborns' perception of a center-occluded object was tested, using stroboscopic motion. Infants (mean age of 72 hr) perceived the object as a connected unit, providing the first evidence that the newborn is capable of filling in gaps in the visible surface layout when the relevant visual information can be detected by his or her immature visual system. [source] Video completion and synthesisCOMPUTER ANIMATION AND VIRTUAL WORLDS (PREV: JNL OF VISUALISATION & COMPUTER ANIMATION), Issue 3-4 2008Chunxia Xiao Abstract This paper presents a new exemplar-based framework for video completion, allowing aesthetically pleasing completion of large space-time holes. We regard video completion as a discrete global optimization on a 3D graph embedded in the space-time video volume. We introduce a new objective function which enforces global spatio-temporal consistency among patches that fill the hole and surrounding it, in terms of both color similarity and motion similarity. The optimization is solved by a novel algorithm, called weighted priority belief propagation (BP), which alleviates the problems of slow convergence and intolerable storage size when using the standard BP. This objective function can also handle video texture synthesis by extending an input video texture to a larger texture region. Experiments on a wide variety of video examples with complex dynamic scenes demonstrate the advantages of our method over existing techniques: salient structures and motion information are much better restored. Copyright © 2008 John Wiley & Sons, Ltd. [source] Generation of tree movement sound effectsCOMPUTER ANIMATION AND VIRTUAL WORLDS (PREV: JNL OF VISUALISATION & COMPUTER ANIMATION), Issue 5 2005Katsutsugu Matsuyama Abstract This paper presents a method for automatically generating sound effects for an animation of branches and leaves moving in the wind. Each tree is divided into branches and leaves, and an independent sound effect generation process is employed for each element. The individual results are then compounded into one sound effect. For the branches, we employ an approach based on the frequencies of experimentally obtained Karman vortex streets. For the leaves, we use the leaf blade state as the input and assume a virtual musical instrument that uses wave tables as the sound source. All computations can be performed independently for each frame step. Therefore, each frame step can be executed on completion of the animation step. The results of the implementation of the approach are presented and it is shown that the process offers the possibility of real-time operation through the use of parallel computing techniques. Copyright © 2005 John Wiley & Sons, Ltd. [source] Trust-based robust scheduling and runtime adaptation of scientific workflowCONCURRENCY AND COMPUTATION: PRACTICE & EXPERIENCE, Issue 16 2009Mingzhong Wang Abstract Robustness and reliability with respect to the successful completion of a schedule are crucial requirements for scheduling in scientific workflow management systems because service providers are becoming autonomous. We introduce a model to incorporate trust, which indicates the probability that a service agent will comply with its commitments to improve the predictability and stability of the schedule. To deal with exceptions during the execution of a schedule, we adapt and evolve the schedule at runtime by interleaving the processes of evaluating, scheduling, executing and monitoring in the life cycle of the workflow management. Experiments show that schedules maximizing participants' trust are more likely to survive and succeed in open and dynamic environments. The results also prove that the proposed approach of workflow evaluation can find the most robust execution flow efficiently, thus avoiding the need of scheduling every possible execution path in the workflow definition. Copyright © 2009 John Wiley & Sons, Ltd. [source] Understanding heart development and congenital heart defects through developmental biology: A segmental approachCONGENITAL ANOMALIES, Issue 4 2005Masahide Sakabe ABSTRACT The heart is the first organ to form and function during development. In the pregastrula chick embryo, cells contributing to the heart are found in the postero-lateral epiblast. During the pregastrula stages, interaction between the posterior epiblast and hypoblast is required for the anterior lateral plate mesoderm (ALM) to form, from which the heart will later develop. This tissue interaction is replaced by an Activin-like signal in culture. During gastrulation, the ALM is committed to the heart lineage by endoderm-secreted BMP and subsequently differentiates into cardiomyocyte. The right and left precardiac mesoderms migrate toward the ventral midline to form the beating primitive heart tube. Then, the heart tube generates a right-side bend, and the d-loop and presumptive heart segments begin to appear segmentally: outflow tract (OT), right ventricle, left ventricle, atrioventricular (AV) canal, atrium and sinus venosus. T-box transcription factors are involved in the formation of the heart segments: Tbx5 identifies the left ventricle and Tbx20 the right ventricle. After the formation of the heart segments, endothelial cells in the OT and AV regions transform into mesenchyme and generate valvuloseptal endocardial cushion tissue. This phenomenon is called endocardial EMT (epithelial-mesenchymal transformation) and is regulated mainly by BMP and TGF,. Finally, heart septa that have developed in the OT, ventricle, AV canal and atrium come into alignment and fuse, resulting in the completion of the four-chambered heart. Altered development seen in the cardiogenetic process is involved in the pathogenesis of congenital heart defects. Therefore, understanding the molecular nature regulating the ,nodal point' during heart development is important in order to understand the etiology of congenital heart defects, as well as normal heart development. [source] Hemiazygos Venous Additional Pulmonary Flow for Successful Total Cavo-pulmonary ConnectionCONGENITAL HEART DISEASE, Issue 5 2007Koichi Sughimoto MD ABSTRACT Patients who underwent only Glenn procedure after being deemed unsuitable candidates for Fontan completion are not small in number, and may develop arterio-venous (AV) pulmonary malformations during the follow-up period. We present the case of a 17-year-old woman with severe systemic desaturation 13 years after Glenn procedure and repair of total anomalous pulmonary venous return. Among other anomalies, the patient disclosed hemiazygos continuation to a persistent left superior vena cava. This case supports the concept that returning flow from the abdominal vein plays an important role in the well-balanced growth of the pulmonary artery and in the inhibition of the pulmonary AV malformation. [source] The Impact of a Brief Expectation Survey on Parental Satisfaction in the Pediatric Emergency DepartmentACADEMIC EMERGENCY MEDICINE, Issue 12 2006Christopher D. Spahr MD Abstract Objectives To determine the effect of physician knowledge of parental expectations on satisfaction with emergency department (ED) care. Methods This was a prospective, controlled, interventional trial involving parents of children presenting to a children's hospital ED. Parents completed an expectation survey on arrival, which was either immediately placed back in the enrollment envelope (control) or shown to the physician caring for the child (intervention). The physician was instructed to initial the expectation survey to acknowledge receipt of the survey. Parents then completed a satisfaction survey at discharge. The primary outcomes were differences in satisfaction with physician review of the expectation survey, as measured by 1) parental ratings of overall care and 2) their willingness to recommend the ED to others. A third (baseline) group completed only a satisfaction survey at discharge. Results A total of 614 (66%) of the 930 enrolled parents completed the study. Intention-to-treat analysis did not show a significant increase in parental satisfaction ratings for either overall care or recommend the ED; however, only 42% of the intervention group surveys had documented physician review. When these initialed surveys were compared with the control group in a per-protocol analysis, there was a significant improvement in parental satisfaction. There were no differences between the control and baseline groups, indicating no effect of the expectation survey completion on satisfaction. Conclusions Physician knowledge of written parental expectations may improve parental satisfaction during an ED visit. Further work is needed to overcome the barriers to physician review of the expectation survey to maximize parent satisfaction. [source] Limitations of relaxation kinetics on muscular workACTA PHYSIOLOGICA, Issue 2 2010J. McDaniel Abstract Aim:, Positive net work produced during cyclic contractions is partially limited by relaxation kinetics, which to date, have not been directly investigated. Therefore, the purpose of this investigation was to determine the influence of relaxation kinetics on cyclic work. Methods:, Soleus muscles of four cats were isolated and subjected to a series of work loops (0.5, 1, 1.5 and 2 Hz cycle frequencies) during which stimulation terminated prior to the end of the shortening phase to allow for complete muscle relaxation and matched discrete sinusoidal shortening contractions during which stimulation remained on until the completion of the shortening phase. Muscle length changes during these protocols were centred on optimum length and were performed across muscle lengths that represented walking gait. Results:, When muscle excursions were centred on Lo relaxation kinetics decreased muscular work by 2.8 ± 0.8%, 12.1 ± 4.1%, 27.9 ± 4.5% and 40.1 ± 5.9% for 0.5, 1, 1.5 and 2 Hz respectively. However, relaxation kinetics did not influence muscular work when muscle excursions represented walking gait. In addition, muscular work produced at muscle lengths associated with walking gait was less than the work produced across Lo (55.7 ± 20.0%, 53.5 ± 21.0%, and 50.1 ± 22.0% for 0.5, 1 and 1.5 Hz respectively). Conclusion:, These results imply that relaxation kinetics are an important factor that limit the ability of muscle to produce work; however, the influence of relaxation kinetics on physiological function may depend on the relation between the optimum length and natural excursion of a muscle. [source] | |||||||||||||||||||||||||||||||||||||||||||||||||