Home About us Contact
|
Home About us Contact | ||
|
|
||
Complementary Role (complementary + role)
Selected AbstractsEvaluation of Cardiac Involvement in Hypereosinophilic Syndrome: Complementary Roles of Transthoracic, Transesophageal, and Contrast EchocardiographyECHOCARDIOGRAPHY, Issue 8 2006Rajesh Shah M.D. Hypereosinophilic syndrome is a rare but important systemic disease with multiple clinical presentations. Approximately 40% of these cases have cardiac involvement. Echocardiography is the most easily available and versatile imaging modality in assessing cardiac involvement in this disease process. As described and reviewed in this case, it may be the first imaging modality to raise suspicion of this disease entity. Hence, clinicians interpreting echocardiograms and caring for patients need to be aware of the manifestations and complementary roles of various echo techniques in delineating cardiac involvement. Furthermore, the importance of a thorough history and laboratory review prior to echocardiography may provide valuable clues which may otherwise be missed. [source] Nurses and Doulas: Complementary Roles to Provide Optimal Maternity CareJOURNAL OF OBSTETRIC, GYNECOLOGIC & NEONATAL NURSING, Issue 2 2006Lois Eve Ballen Staff in maternity-care facilities are seeing an increase in doulas, nonmedical childbirth assistants, who are trained to provide continuous physical, emotional, and informational labor support. The long-term medical and psychosocial benefits are well documented. In this article, misconceptions about the doula's role are corrected, and suggestions are offered on ways to improve communication between health care providers and doulas. Together, nurses and doulas can provide birthing women with a safe and satisfying birth. JOGNN, 35, 304-311; 2006. DOI: 10.1111/J.1552-6909.2006.00041.x [source] Complementary roles of platelets and coagulation in thrombus formation on plaques acutely ruptured by targeted ultrasound treatment: a novel intravital modelJOURNAL OF THROMBOSIS AND HAEMOSTASIS, Issue 1 2009M. J. E. KUIJPERS Summary.,Background:,Atherothrombosis is a major cause of cardiovascular events. However, animal models to study this process are scarce. Objectives:,We describe the first murine model of acute thrombus formation upon plaque rupture to study atherothrombosis by intravital fluorescence microscopy. Methods:,Localized rupture of an atherosclerotic plaque in a carotid artery from Apoe,/, mice was induced in vivo using ultrasound. Rupture of the plaque and formation of localized thrombi were verified by two-photon laser scanning microscopy (TPLSM) in isolated arteries, and by immunohistochemistry. The thrombotic reaction was quantified by intravital fluorescence microscopy. Results:,Inspection of the ultrasound-treated plaques by histochemistry and TPLSM demonstrated local damage, collagen exposure, luminal thrombus formation as well as intra-plaque intrusion of erythrocytes and fibrin. Ultrasound treatment of healthy carotid arteries resulted in endothelial damage and limited platelet adhesion. Real-time intravital fluorescence microscopy demonstrated rapid platelet deposition on plaques and formation of a single thrombus that remained subocclusive. The thrombotic process was antagonized by thrombin inhibition, or by blocking of collagen or adenosine diphosphate receptor pathways. Multiple thrombi were formed in 70% of mice lacking CD40L. Conclusions:,Targeted rupture of murine plaques results in collagen exposure and non-occlusive thrombus formation. The thrombotic process relies on platelet activation as well as on thrombin generation and coagulation, and is sensitive to established and novel antithrombotic medication. This model provides new possibilities to study atherothrombosis in vivo. [source] Complementary roles of prenatal sonography and magnetic resonance imaging in diagnosis of fetal renal anomaliesAUSTRALIAN AND NEW ZEALAND JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Issue 3 2010Ibrahim A. ABDELAZIM Objectives:, This study was designed to assess the role of magnetic resonance imaging (MRI) in refining the diagnosis of prenatally suspected fetal renal abnormalities following screening ultrasound. Patients and methods:, Twenty pregnant women, with suspected fetal renal abnormality detected during screening ultrasound and more than 14 weeks' gestation, were included in this observational prospective study at Ain Shams University Maternity Hospital from March 2004 to March 2005 after informed consent and after approval of the study protocol by the institute ethics committee. Results:, The MRI could diagnose correctly 10 cases of hydronephrosis, one case of polycystic kidney disease (PCKD), one case of RA, two normal case and two cases of intra-abdominal masses (IA Mass) (16 of 18 cases). The prenatal ultrasound could diagnose correctly eight cases of hydronephrosis, one case of PCKD, one case of renal agenesis, one case of multicystic kidney disease and one case of IA Mass (12 of 18 cases). The prenatal ultrasound and MRI gave different diagnoses in eight cases and gave the same diagnosis in 12 cases. The MRI could diagnose the aetiology of congenital renal cysts in 10 of the 20 studied cases (50%). Conclusion:, Magnetic resonance imaging can be used as a complementary tool in the assessment of sonographically suspected fetal renal anomalies. [source] Board Monitoring, Regulation, and Performance in the Banking Industry: Evidence from the Market for Corporate ControlCORPORATE GOVERNANCE, Issue 5 2010Jens Hagendorff ABSTRACT Manuscript Type: Empirical Research Question/Issue: The specific monitoring effect of boards of directors versus industry regulation is unclear. In this paper, we examine how the interaction between bank-level monitoring and regulatory regimes influences the announcement period returns of acquiring banks in the US and twelve European economies. Research Findings/Insights: We study three board monitoring mechanisms , independence, CEO-chair duality, and diversity , and analyze their effectiveness in preventing underperforming merger strategies under bank regulators of varying strictness. Only under strict banking regulation regimes, do board independence and diversity improve acquisition performance. In less strict regulatory environments, corporate governance is virtually irrelevant in improving the performance outcomes of merger activities. Theoretical/Academic Implications: Our results indicate a complementary role between monitoring by boards and bank regulation. This study is the first to report evidence consistent with complementarity by investigating the effectiveness (rather than the prevalence) of governance arrangements across regulatory regimes. Practitioner/Policy Implications: Our work offers insights to policymakers charged with improving the quality of decision-making at financial institutions. Attempts to improve the ability of bank boards to critically assess managerial initiatives are most likely to be successful if internal governance is accompanied by strict industry regulation. [source] The Role of Research Institutions in Seed,related Disaster Relief: Seeds of Hope Experiences in RwandaDISASTERS, Issue 4 2002Robin A. Buruchara The article describes the efforts of a coalition of agricultural research centres, Seeds of Hope (SOH) in the rebuilding of Rwanda, after the genocide and war of 1994. Research involvement in emergency relief and rehabilitation was unusual at the time and SOH had to forge its unique complementary role. Focusing on crop and variety development and conservation it: provided technical advice to relief agencies on seed procurement; used its baseline ken to assess the effects of war on seed diversity and seed security; made preparations to restore specific germplasm (which, fortunately, proved unnecessary) and spent substantial effort on rebuilding human resource capacity in research as well as basic scientific facilities. The involvement of SOH highlighted the critical, yet very different, roles for research during emergency versus rehabilitation periods and demonstrated the cost effectiveness of building in a diagnostic component , before massive seed or germplasm distributions are programmed. [source] Advection of anchovy (Engraulis encrasicolus) larvae along the Catalan continental slope (NW Mediterranean)FISHERIES OCEANOGRAPHY, Issue 2 2007A. SABATÉS Abstract The Gulf of Lions is one of the main anchovy (Engraulis encrasicolus) spawning areas in the NW Mediterranean. During the spring, low-salinity surface water from the outflow of the Rhône is advected by the shelf-slope current along the continental slope off the Catalan coast. In June 2000, a Lagrangian experiment tracking these low-salinity surface waters was conducted to assess the importance of this transport mechanism for anchovy larvae and to determine the suitability of the tracked surface waters for survival of anchovy larvae. The experiment consisted of sampling the tracked water parcel for 10 days with three drifters launched at the core of the shelf-slope current where low-salinity surface waters were detected. The survey was completed by sampling the surrounding waters. Anchovy larvae from the spawning area in the Gulf of Lions were advected towards the south in the low-salinity waters. The size increase of anchovy larvae throughout the Lagrangian tracking closely followed the general growth rate calculated by otolith analysis (0.65 mm day,1). However, advection by the current was not the only mechanism of anchovy larval transport. A series of anticyclonic eddies, originated in the Gulf of Lions and advected southwards, seemed to play a complementary role in the transport of larvae from the spawning ground towards the nursery areas. These eddies not only contributed to larval transport but also prevented their dispersion. These transport and aggregation mechanisms may be important for anchovy populations along the Catalan coast and require further study. [source] Using pseudo amino acid composition to predict protein structural class: Approached by incorporating 400 dipeptide componentsJOURNAL OF COMPUTATIONAL CHEMISTRY, Issue 9 2007Hao Lin Abstract The proteins structure can be mainly classified into four classes: all-,, all - ,, ,/,, and , + , protein according to their chain fold topologies. For the purpose of predicting the protein structural class, a new predicting algorithm, in which the increment of diversity combines with Quadratic Discriminant analysis, is presented to study and predict protein structural class. On the basis of the concept of the pseudo amino acid composition (Chou, Proteins: Struct Funct Genet 2001, 43, 246; Erratum: Proteins Struct Funct Genet 2001, 44, 60), 400 dipeptide components and 20 amino acid composition are, respectively, selected as parameters of diversity source. Total of 204 nonhomologous proteins constructed by Chou (Chou, Biochem Biophys Res Commun 1999, 264, 216) are used for training and testing the predictive model. The predicted results by using the pseudo amino acids approach as proposed in this paper can remarkably improve the success rates, and hence the current method may play a complementary role to other existing methods for predicting protein structural classification. © 2007 Wiley Periodicals, Inc. J Comput Chem, 2007 [source] The Internet and Anti-War Activism: A Case Study of Information, Expression, and ActionJOURNAL OF COMPUTER-MEDIATED COMMUNICATION, Issue 1 2006Seungahn Nah This case study examines how traditional and Internet news use, as well as face-to-face and online political discussion, contributed to political participation during the period leading up to the Iraq War. A Web-based survey of political dissenters (N = 307) conducted at the start of the U.S.-led invasion of Iraq provides the data used to examine the relationships among informational media use, online and face-to-face political discussion, and political participation among the respondents, who were recruited through blogs, discussion boards, and listservs opposing the Iraq war. Analyses reveal that among these respondents, Internet news use contributed to both face-to-face and online discussion about the situation in Iraq. Online and face-to-face political discussion mediated certain news media effects on anti-war political participation. The study stresses the complementary role of Web news use and online political discussion relative to traditional modes of political communication in spurring political participation. [source] Susceptibility Contrast and Arterial Spin Labeled Perfusion MRI in Cerebrovascular DiseaseJOURNAL OF NEUROIMAGING, Issue 1 2003Ronald L. Wolf MD ABSTRACT Purpose. To directly compare dynamic susceptibility contrast (DSC) and continuous arterial spin labeled (CASL) magnetic resonance (MR) perfusion techniques in patients with known cerebrovascular disease, with the goals of identifying possible pitfalls in interpretation and determining potential for a complementary role in this setting. Methods. DSC and CASL MR perfusion studies were performed and compared in 11 patients with acute and/or chronic cerebrovascular disease. Using an automated segmentation technique, Pearson correlation coefficients were generated for CASL perfusion measurements compared to DSC perfusion maps (time-to-peak [TTP], relative cerebral blood volume [rCBV], cerebral blood flow [rCBF], and mean transit time [MTT]) by hemisphere and vascular territory. Results. TTP maps obtained using DSC perfusion MR correlated best both subjectively and objectively with CASL perfusion MRmeasurements when all patients studied were considered. If patients with a major transit delay were excluded, DSC rCBF correlated best with CASL CBF measurements. Conclusion. There may be a complementary role for CASL and DSC perfusion MR methods in cerebrovascular disease, especially in the setting of a marked transit delay. [source] Pulsed dye laser: what's new in non-vascular lesions?JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY & VENEREOLOGY, Issue 7 2007S Karsai Abstract Background and objective, In dermatology, the pulsed dye laser (PDL) is the therapeutic instrument of choice for treating most superficial cutaneous vascular lesions. In addition, clinical experience over the last decade allowed us to treat patients with an ever increasing number of non-vascular indications. The purpose of this report is to summarize and critically appraise the scientific evidence that support the role of PDL in treating non-vascular skin lesions. Methods, A literature-based study has been conducted, including the review of publications over the period January 1995 to December 2006, using the Medline Database. We also included our own experience in managing non-vascular lesions with the PDL. Four sets of preoperative and postoperative photos are presented. Results, For viral skin lesions, PDL proved to be an alternative to other therapy options. This applies particularly to periungual warts and mollusca contagiosa. The mechanism of PDL with inflammatory dermatoses has not yet been elucidated. The effect seems to be better if there is a vascular component to the disease. With most of these indications (such as psoriasis and acne), PDL currently plays a rather minor or complementary role. Regarding collagen remodelling (hypertrophic scars, keloids, stretch marks, and skin rejuvenation), the question of whether a therapy makes sense or not has to be decided from case to case. Conclusion, With PDL, it is possible to achieve good results with numerous, partly less well-known indications (i.e. lupus erythematosu). With other diseases, PDL has so far been considered to be a complementary therapy method or to be in an experimental state. [source] Using Qualitative and Quantitative Information in Academic Decision MakingNEW DIRECTIONS FOR INSTITUTIONAL RESEARCH, Issue 112 2001Ann S. Ferren The authors use specific examples to illustrate the complementary role that qualitative (contextual) and quantitative decision support can play in support of the management of academic affairs. [source] Artichoke leaf extract reduces oxidative stress and lipoprotein dyshomeostasis in rats fed on high cholesterol dietPHYTOTHERAPY RESEARCH, Issue 4 2010Z. Küskü-Kiraz Abstract Hypercholesterolemia and lipid peroxidation play complementary role in atherosclerosis. Artichoke leaf extract (ALE) is rich in natural antioxidants and has a cholesterol-reducing effect. However, there is no study investigating the effect of ALE on lipid levels and lipid peroxidation in experimental hypercholesterolemic conditions. Rats were fed on 4% (w/w) cholesterol and 1% (w/w) cholic acid supplemented diet for 1 month. ALE (1.5,g/kg/day) was given by gavage during the last 2 weeks. Serum lipid composition, malondialdehyde (MDA) and diene conjugate (DC) levels and plasma antioxidant activity (AOA) were measured. In addition, endogenous DC and copper-induced MDA levels were determined in apo B-containing lipoproteins (LDL+VLDL fraction). Serum cholesterol and triglyceride levels and the ratio of cholesterol to HDL-cholesterol decreased due to ALE treatment in rats fed on HC diet. Significant decreases in serum MDA and DC levels and increases in plasma AOA were detected in serum in ALE-treated hypercholesterolemic rats. Endogenous DC and copper-induced MDA levels were also lower in LDL+VLDL fraction due to ALE-treatment in hypercholesterolemic rats. Our results indicate that ALE may be useful for the prevention of hypercholesterolemia-induced pro-oxidant state in LDL+VLDL fraction and the reduction of increased serum cholesterol and triglyceride levels. Copyright © 2009 John Wiley & Sons, Ltd. [source] Metabolomics: Current technologies and future trendsPROTEINS: STRUCTURE, FUNCTION AND BIOINFORMATICS, Issue 17 2006Katherine Hollywood Abstract The ability to sequence whole genomes has taught us that our knowledge with respect to gene function is rather limited with typically 30,40% of open reading frames having no known function. Thus, within the life sciences there is a need for determination of the biological function of these so-called orphan genes, some of which may be molecular targets for therapeutic intervention. The search for specific mRNA, proteins, or metabolites that can serve as diagnostic markers has also increased, as has the fact that these biomarkers may be useful in following and predicting disease progression or response to therapy. Functional analyses have become increasingly popular. They include investigations at the level of gene expression (transcriptomics), protein translation (proteomics) and more recently the metabolite network (metabolomics). This article provides an overview of metabolomics and discusses its complementary role with transcriptomics and proteomics, and within system biology. It highlights how metabolome analyses are conducted and how the highly complex data that are generated are analysed. Non-invasive footprinting analysis is also discussed as this has many applications to in,vitro cell systems. Finally, for studying biotic or abiotic stresses on animals, plants or microbes, we believe that metabolomics could very easily be applied to large populations, because this approach tends to be of higher throughput and generally lower cost than transcriptomics and proteomics, whilst also providing indications of which area of metabolism may be affected by external perturbation. [source] Proteomic profiling for cancer progression: Differential display analysis for the expression of intracellular proteins between regressive and progressive cancer cell linesPROTEINS: STRUCTURE, FUNCTION AND BIOINFORMATICS, Issue 4 2005Eiko Hayashi Abstract Tumor development and progression consist of a series of complex processes involving multiple changes in gene expression (Paolo et al. Physiol. Rev., 1993, 73, 161,195; Lance et al. Cell., 1991, 64, 327,336). Tumor cells acquire an invasive and metastatic phenotype that is the main cause of death for cancer patients. Therefore, for early diagnosis and effective therapeutic intervention, we need to detect the alterations associated with transition from benign to malignant tumor cells on a molecular basis. To unravel alterations concerned with tumor progression, the proteomic approach has attracted great attention because it can identify qualitative and quantitative changes in protein composition, including post-translational modifications. In this study, we performed proteomic differential display analysis for the expression of intracellular proteins in the regressive cancer cell line QR-32 and the inflammatory cell-promoting progressive cancer cell line QRsP-11 of murine fibrosarcoma by two-dimensional gel electrophoresis and mass spectrometry using an Agilent 1100 LC/MSD Trap XCT. We found 11,protein spots whose expression was different between QR-32 and QRsP-11 cells and identified nine proteins, seven of which, calreticulin precursor, tropomyosin,1 , chain, annexin,A5, heat shock protein (HSP)90-,, HSP90-,, PEBP, and Prx,II, were over-expressed, and two, Anp32e and HDGF, which were down-regulated. The results suggest an important complementary role for proteomics in identification of molecular abnormalities in tumor progression. [source] Medical and midwifery students: how do they view their respective roles on the labour ward?AUSTRALIAN AND NEW ZEALAND JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Issue 4 2002Julie A Quinlivan ABSTRACT Background It has been suggested that much of the medical and midwifery student curricula on normal pregnancy and birth could be taught as a co-operative effort between obstetric and midwifery staff. One important element of a successful combined teaching strategy would involve a determination of the extent to which the students themselves identify common learning objectives. Aim The aim of the present study was to survey medical and midwifery students about how they perceived their respective learning roles on the delivery suite. Methods A descriptive cross-sectional survey study was undertaken. The study venue was an Australian teaching and tertiary referral hospital in obstetrics and gynaecology. Survey participants were medical students who had just completed a 10 week clinical attachment in obstetrics and gynaecology during the 5th year of a six year undergraduate medical curriculum and midwifery students undertaking a one year full-time (or two year part-time) postgraduate diploma in midwifery. Results Of 130 and 52 questionnaires distributed to medical and midwifery students, response rates of 72% and 52% were achieved respectively. The key finding was that students reported a lesser role for their professional colleagues than they identified for themselves. Some medical students lacked an understanding of the role of midwives as 8%, 10%, and 23% did not feel that student midwives should observe or perform a normal birth or neonatal assessment respectively. Of equal concern, 7%, 22%, 26% and 85% of student midwives did not identify a role for medical students to observe or perform a normal birth, neonatal assessment or provide advice on breastfeeding respectively. Summary Medical and midwifery students are placed in a competitive framework and some students may not understand the complementary role of their future colleagues. Interdisciplinary teaching may facilitate co-operation between the professions and improve working relationships. [source] Combining Biogeographic and Phylogenetic Data to Examine Primate Speciation: An Example Using Cercopithecin MonkeysBIOTROPICA, Issue 4 2009Jason M. Kamilar ABSTRACT We combined phylogenetic and biogeographic data to examine the mode of speciation in a group of African monkeys, the Cercopithecini. If allopatric speciation is the major force producing species, then there should be a positive relationship between the relative divergence time of taxa and their degree of geographic range overlap. Alternatively, an opposite relationship between divergence time and geographic range overlap is consistent with sympatric speciation as the main mechanism underlying the cercopithecin radiation. We collected biogeographic and phylogenetic data for 19 guenon species from the literature. We digitized geographic range maps and utilized three different phylogenetic hypotheses based on Y chromosome, X chromosome, and mitochondrial (mtDNA) data. We used regressions with Monte Carlo simulation to examine the relationship between the relative time since divergence of taxa and their degree of geographic range overlap. We found that there was a positive relationship between relative divergence time and the proportion of geographic range overlap between taxa using all three molecular data sets. Our findings provide evidence for allopatric speciation being the common mode of diversification in the cercopithecin clade. Because most of these primates are forest adapted mammals, the cyclical contraction and expansion of African forests from the late Miocene to the present has likely been an important factor driving allopatric speciation. In addition, geographic barriers such as the Congo and Sanaga rivers have probably played a complementary role in producing new species within the clade. [source] Design Of Clinical Pharmacology TrialsCLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, Issue 11 2001Stephen B Duffull SUMMARY 1. There are a variety of methods that could be used to increase the efficiency of the design of experiments. However, it is only recently that such methods have been considered in the design of clinical pharmacology trials. 2. Two such methods, termed data-dependent (e.g. simulation) and data-independent (e.g. analytical evaluation of the information in a particular design), are becoming increasingly used as efficient methods for designing clinical trials. These two design methods have tended to be viewed as competitive, although a complementary role in design is proposed here. 3. The impetus for the use of these two methods has been the need for a more fully integrated approach to the drug development process that specifically allows for sequential development (i.e. where the results of early phase studies influence later-phase studies). 4. The present article briefly presents the background and theory that underpins both the data-dependent and -independent methods with the use of illustrative examples from the literature. In addition, the potential advantages and disadvantages of each method are discussed. [source] Almost-anywhere theories: Reductionism and universality of emergenceCOMPLEXITY, Issue 6 2010Ignazio Licata Abstract Here, we aim to show that reductionism and emergence play a complementary role in understanding natural processes and in the dynamics of science explanation. In particular, we will show that the renormalization group,one of the most refined tools of Theoretical Physics,allows to understand the importance of emergent processes' role in Nature identifying them as universal organization processes, that is, they are scale independent. We can use the syntaxes of Quantum Field Theory and the processes of Spontaneous Symmetry Breaking as a trans-disciplinary theoretical scenario for many other forms of complexity, especially the biological and cognitive ones. © 2010 Wiley Periodicals, Inc. Complexity, 2010 [source] Evaluation of Cardiac Involvement in Hypereosinophilic Syndrome: Complementary Roles of Transthoracic, Transesophageal, and Contrast EchocardiographyECHOCARDIOGRAPHY, Issue 8 2006Rajesh Shah M.D. Hypereosinophilic syndrome is a rare but important systemic disease with multiple clinical presentations. Approximately 40% of these cases have cardiac involvement. Echocardiography is the most easily available and versatile imaging modality in assessing cardiac involvement in this disease process. As described and reviewed in this case, it may be the first imaging modality to raise suspicion of this disease entity. Hence, clinicians interpreting echocardiograms and caring for patients need to be aware of the manifestations and complementary roles of various echo techniques in delineating cardiac involvement. Furthermore, the importance of a thorough history and laboratory review prior to echocardiography may provide valuable clues which may otherwise be missed. [source] A model of treatment decision making when patients have advanced cancer: how do cancer treatment doctors and nurses contribute to the process?EUROPEAN JOURNAL OF CANCER CARE, Issue 4 2010L. MCCULLOUGH msc, nurse leader clinical support services MCCULLOUGH L., MCKINLAY E., BARTHOW C., MOSS C. & WISE D. (2010) European Journal of Cancer Care A model of treatment decision making when patients have advanced cancer: how do cancer treatment doctors and nurses contribute to the process? This qualitative study describes how doctors and nurses report their contribution to treatment decision-making processes when patients have advanced cancer. Thirteen nurses and eight doctors involved in cancer treatment and palliation in one geographical location in New Zealand participated in the study. Data were collected using qualitative in-depth, face-to-face interviews. Content analysis revealed a complex context of decision making influenced by doctors and nurses as well as the patient and other factors. A model of clinician and patient decision making emerged with a distinct and cyclical process as advanced cancer remits and progresses. When patients have advanced cancer, nurses and doctors describe a predictable model of decision making in which they both contribute and that cycles through short- and long-term remissions; often nowadays to the point of the patient dying. In conclusion, the findings suggest doctors and nurses have different but complementary roles in what, when and how treatment choices are negotiated with patients, nevertheless within a distinct model of decision making. [source] Advice Given to Parents on Welcoming a Second Child: A Critical Review,FAMILY RELATIONS, Issue 1 2002Laurie Kramer A review of popular press books and articles for parents published between 1975 and 2000 was conducted to delineate the areas in which the advice given to parents about the transition to a second child is consistent with or diverges from the results of relevant research. Although popular advice reflects available research in certain areas (e.g., encouraging sibling caregiving), research to substantiate other directives (e.g., sibling preparation classes) is lacking. Key research findings about how to promote harmonious sibling relationships often are not represented in popular writings. These results highlight the need for researchers and popular press writers to acknowledge their complementary roles in disseminating information. [source] The evaluation of health and social care partnerships: an analysis of approaches and synthesis for the futureHEALTH & SOCIAL CARE IN THE COMMUNITY, Issue 5 2006Helen Dickinson MA BAArticle first published online: 17 AUG 200 Abstract At a time when health and social care partnerships are continuing to occupy a central role within the UK government's policy strategy, researchers are increasingly being required to evaluate such organisational entities. This paper looks at a wide range of approaches which have been utilised to evaluate health and social care partnerships, and suggests that theory-led strategies are better able to address the complexities associated with such forms of evaluation. In particular, the author suggests that a combination of theories of change and realistic evaluation seems to be the most fruitful in tackling the evaluation difficulties associated with partnerships. Despite both being theory-led evaluation strategies, they fulfil quite different and complementary roles. However, both these approaches have been found to have some limitations in practice. Therefore, this paper suggests that interpreting these approaches through a framework of critical realism may overcome a number of these difficulties. [source] The Tribolium chitin synthase genes TcCHS1 and TcCHS2 are specialized for synthesis of epidermal cuticle and midgut peritrophic matrixINSECT MOLECULAR BIOLOGY, Issue 5 2005Y. Arakane Abstract Functional analysis of the two chitin synthase genes, TcCHS1 and TcCHS2, in the red flour beetle, Tribolium castaneum, revealed unique and complementary roles for each gene. TcCHS1- specific RNA interference (RNAi) disrupted all three types of moult (larval,larval, larval,pupal and pupal,adult) and greatly reduced whole-body chitin content. Exon-specific RNAi showed that splice variant 8a of TcCHS1 was required for both the larval-pupal and pupal-adult moults, whereas splice variant 8b was required only for the latter. TcCHS2 -specific RNAi had no effect on metamorphosis or on total body chitin content. However, RNAi-mediated down-regulation of TcCHS2, but not TcCHS1, led to cessation of feeding, a dramatic shrinkage in larval size and reduced chitin content in the midgut. [source] The stability of stars of triangular equilibrium plate elementsINTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN ENGINEERING, Issue 7 2009E. A. W. Maunder Abstract Equilibrium models for finite element analyses are becoming increasingly important in complementary roles to those from conventional conforming models, but when formulating equilibrium models questions of stability, or admissibility of loads, are of major concern. This paper addresses these questions in the context of flat plates modelled with triangular hybrid elements involving membrane and/or flexural actions. Patches of elements that share a common vertex are considered, and such patches are termed stars. Stars may be used in global analyses as assemblies of elements forming macro-elements, or in local analyses. The conditions for stability, or the existence and number of spurious kinematic modes, are determined in a general algebraic procedure for any degree of the interpolation polynomials and for any geometric configuration. The procedure involves the determination of the rank of a compatibility matrix by its transformation to row echelon form. Examples are presented to illustrate some of the characteristics of spurious kinematic modes when they exist in stars with open or closed links. Copyright © 2008 John Wiley & Sons, Ltd. [source] Computational characterization of nucleotide bases: Molecular surface electrostatic potentials and local ionization energies, and local polarization energiesINTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY, Issue 3-4 2001Jane S. Murray Abstract Electrostatic potentials and local ionization energies have been computed at the HF/6-31G* level on the molecular surfaces of the five nucleotide bases. The potentials are analyzed in terms of their most positive and negative values as well as several statistically defined quantities that reflect their patterns over the entire surface. Considerable charge separation and variability are found for all five molecules. The results are consistent with the base pairing that is known to occur. The observed reactive behavior toward electrophiles can be interpreted in terms of the complementary roles of the surface potential and the local electron lability. Local polarization energies, corresponding to a test charge being placed at specific points above the molecules, are also calculated (HF/6-31+G*), and their relationship to the local ionization energies is examined. © 2001 John Wiley & Sons, Inc. Int J Quant Chem 83: 245,254, 2001 [source] Correlation of the apparent diffusion coefficient and the creatine level in early ischemic stroke: A comparison of different patterns by magnetic resonanceJOURNAL OF MAGNETIC RESONANCE IMAGING, Issue 3 2001Helmut Rumpel PhD Abstract It has been reported that reduction of the apparent diffusion coefficient (ADC) after stroke can persist for several days, after which the ADC increases gradually to an abnormally high level. We evaluated ADC values of stroke lesions and compared the results to the cellular density of the lesion by means of the creatine (Cre) level. This two-parameter estimation is of particular relevance in ascertaining the underlying cellular status. Lesion-to-contralateral ADC ratios (ADCn) were obtained based on diffusion-weighted echo-planar and fast spin-echo imaging. Single-voxel localized spectroscopy was used for quantification of cerebral metabolites in infarcted regions. Their levels were also compared to that in homotopic contralateral regions. Fifteen patients with ischemic stroke were examined at times ranging from 18,88 hours following the onset of symptoms. In the stroke lesion, there was a significant correlation between the ADC and the Cre level showing that the higher the cell density the lower the ADC value. For ADCn vs. the lesion Cre concentration and the lesion-to-contralateral Cre ratio (Cren), the strengths of relationship were R2 = 0.70 and 0.58, respectively. It is concluded that ADC is a good reflection of cell density. Greatly lowered ADC values occur within the context of a stable cellularity. ADC and the Cre level have complementary roles in the characterization of stroke lesion with regard to the sequential stage. J. Magn. Reson. Imaging 2001;13:335,343. © 2001 Wiley-Liss, Inc. [source] Gender and parents' reactions to children's emotion during the preschool yearsNEW DIRECTIONS FOR CHILD & ADOLESCENT DEVELOPMENT, Issue 128 2010Amy Kennedy Root In this chapter, the authors examine the differences between mothers and fathers in the socialization of specific emotions in preschool-aged boys and girls. They argue that mothers and fathers play both distinct and complementary roles in the development of children's emotional competence; these roles are influenced both by parents' own gender, as well as the child's gender and the type of emotion being socialized. Through analyses of descriptive data, it appears that mothers and fathers respond to their children's emotions differently. The authors provide a discussion of the potential underlying reasons and potential implications for distinct emotion socialization by mothers and fathers. © Wiley Periodicals, Inc. [source] Proteome characterization of human T helper 1 and 2 cellsPROTEINS: STRUCTURE, FUNCTION AND BIOINFORMATICS, Issue 1 2004Kirsi Rautajoki Abstract T helper (Th) cells can be polarized into two different main subtypes, Th1 and Th2 cells. Their activation is linked to the eradication of different pathogens and to dissimilar immunological dysfunctions, which implies differences also in their protein expression patterns. To identify these differences, CD4+ T cells were isolated from human cord blood, polarized in vitro to Th1 and Th2 and activated via CD3 and CD28. Cells were lysed, soluble proteins were separated with two-dimensional electrophoresis and differing protein spots were identified with peptide mass fingerprinting. The expression of 14 proteins differed in Th1 and Th2 cells after both 7 and 14 days of polarization. Twelve of the proteins could be identified, most of which are new in this context. Two proteins were differentially modified in the two cell types. Especially, N -terminal acetylation of cyclophilin A was stronger in Th1 than in Th2 cells. To compare the RNA and the protein levels of the identified genes, mRNA expression was measured with Affymetrix oligonucleotide microarrays (HG-U133A). The mRNA and protein expression level correlated only in six cases out of eleven, which highlights the complementary roles that proteomics and transcriptomics have in the elucidation of biological phenomena. [source] The roots of empathy and aggression in analysisTHE JOURNAL OF ANALYTICAL PSYCHOLOGY, Issue 4 2005Richard Kradin Abstract:, Empathy and interpretation have complementary roles in analysis. Empathy diminishes psychological arousal, ego-defences, and promotes the therapeutic relationship. Interpretation, when adopted in the service of character analysis and the uncovering of unconscious conflict, represents one element of a larger set of interventions termed analytic aggression, whose primary goal is to promote insight. Psychoanalysis has been increasingly influenced by derivative theories that promote the therapeutic relationship. Clinical observations suggest that the application of analytic aggression has diminished and that many modern treatments may have become overly skewed towards empathic approaches. This paper explores ethical humanism, Jamesian typology, and feminine psychology, as factors that have contributed to the diminished emphasis on analytic aggression in practice. Eastern myth and Buddhist psychology are used to explicate the core features of narcissistic mental structuring and to support the continued importance of analytic aggression in its treatment. Case material is examined to elucidate the benefits and limits of analytic aggression. [source] | ||||||||||||||||||||||||||||||||||