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Compressive Load (compressive + load)
Selected AbstractsIn vitro study of mean loads and modes of failure of all-ceramic crowns cemented with light-cured or dual-cured luting cement, after 1 and 30 d of storageEUROPEAN JOURNAL OF ORAL SCIENCES, Issue 1 2008Melissa-L. This study compared the mean loads and modes of failure of teeth restored with all-ceramic crowns (ACCs) cemented with dual-cured (RelyX ARC; 3M ESPE) or light-cured (RelyX Veneer; 3M ESPE) luting cements. Clinically, there are advantages of light-cured cements over the recommended dual-cured cements, namely increased working time, improved handling, colour stability, and a homogenous mix. Forty, sound, extracted, human, premolar teeth underwent a standardized preparation for ACCs. IPS Empress (Ivoclar-Vivadent) crowns of standard dimensions were fabricated and 20 were cemented with each cement. The crowns were stored for 1 or 30 d in water and subjected to a compressive load to failure at 0.017 mm s,1. There were no significant differences in loads at failure, between each cement group, at each storage period, and there were no significant differences in loads at failure, for each cement, at 1 and 30 d of storage. There were also no significant differences in modes of failure between each cement group. Before recommending light-cured cement as an alternative to dual-cured cement for the cementation of all-ceramic crowns, further research is required to establish the depth of ceramic at which light-cured lutes fail to polymerize completely. [source] Fracture strength of bovine incisors after intra-radicular treatment with MTA in an experimental immature tooth modelINTERNATIONAL ENDODONTIC JOURNAL, Issue 9 2007E. A. Bortoluzzi Abstract Aim, To evaluate, using an experimental immature tooth model, the fracture resistance of bovine incisors submitted to different reinforcement treatments with mineral trioxide aggregate (MTA). Methodology, An immature tooth model was created by sectioning the coronal and apical portions of 40 bovine incisors 8 mm above and 12 mm below the cementoenamel junction. The root canals were irrigated with 1.0% sodium hypochlorite. They were enlarged both coronally and apically using number 703 carbide burs (ISO: 500,104-168-007-021) and their internal diameter was standardized to 2.1 mm. The specimens were assigned to four groups (n = 10): GI-control (without filling); GII-apical MTA plug + filling with gutta-percha and endodontic sealer; GIII-filling with MTA; GIV-apical MTA plug + filling with MTA + metallic post (Reforpost I). A polyether impression material was used to simulate the periodontal ligament. The specimens were submitted to a compressive load at a crosshead speed of 0.5 mm min,1 in a servo-hydraulic universal testing machine (MTS 810) applied at 45° to the long axis of the tooth until failure. Data were submitted to statistical analysis by the Kruskal,Wallis test at 5% significance level. Results, GIV presented the highest fracture resistance (32.7N) and differed significantly from the other groups (P < 0.05). No statistically difference was found between GII (16.6N) and GIII (23.4N) (P > 0.05). GIII had a significantly higher fracture resistance than GI (P < 0.05). Conclusions, The use of MTA + metallic post as an intra-radicular reinforcement treatment increased the resistance to fracture of weakened bovine teeth in an experimental immature tooth model. [source] Stress analysis of the anterior tibial post in posterior stabilized knee prosthesesJOURNAL OF ORTHOPAEDIC RESEARCH, Issue 4 2007Chang-Hung Huang Abstract Recent retrieval studies have indicated a high incidence of polyethylene wear on the anterior tibial post caused by impingement. This study investigated the influences of post-cam design features and component alignment on the stress distribution in the anterior tibial post when subjected to the impingement loading. Two three-dimensional finite element models of posterior stabilized knee prostheses were constructed, one with flat on flat (FF) and another with curve on curve (CC) contact surfaces between anterior tibial post and femoral cam. The polyethylene insert was modeled with elastoplastic properties. Nine cases, three hyperextension angles (0°, 5°, and 10°) combined with three axial tibial rotations (0°, 2.5°, and 5°) simulating different component alignments were analyzed. A vertical compressive load of 2,000 N and an extension moment of 45 Nm were applied simultaneously. The FF model had larger stress increases than the CC model in both hyperextension and tibial rotation compared with the neutral position. The maximum increase for the FF model was 68% in peak contact stress, 125% in von Mises stress, and 58% in tensile stress in the extreme case of 10° of hyperextension combined with 5° of axial rotation. Stress concentration was found at the anterior corner of the post in the FF model; this was not found in the CC model. The curve on curve design can reduce edge loading on the tibial post, especially during axial tibiofemoral rotation. © 2007 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 25:442,449, 2007 [source] Nonweight-bearing anterior knee laxity is related to anterior tibial translation during transition from nonweight bearing to weight bearingJOURNAL OF ORTHOPAEDIC RESEARCH, Issue 3 2006Sandra J. Shultz Abstract We examined the relationship between anterior knee laxity (AKL), evaluated while the knee was nonweight bearing, and anterior translation of the tibia relative to the femur (ATT), evaluated when the knee transitioned from nonweight-bearing to weight-bearing conditions in response to an applied compressive load at the foot. Twenty subjects with normal knees (10 M, 10 F; 25.2,±,4.1 years, 169.8,±,11.5 cm, 71.6,±,16.9 kg) underwent measurements of AKL and ATT of the right knee on 2 days. AKL was measured at 133N with the KT-2000Ô. ATT was measured with the Vermont Knee Laxity Device and electromagnetic position sensors attached to the patella and the anteromedial aspect of the proximal tibia. Three trials for each measure were averaged and analyzed. Measurement consistency was high for both AKL (ICC,=,0.97; SEM,=,0.44 mm) and ATT (ICC,=,0.88; SEM,=,0.84 mm). Linear regression revealed that AKL predicted 35.5% of the variance in ATT (p,=,0.006), with a prediction equation of YATT,=,3.20,+,0.543(XAKL). Our findings suggest that increased AKL is associated with increased ATT as the knee transitions from nonweight-bearing to weight-bearing conditions. The potential for increased knee joint laxity to disrupt normal knee biomechanics during activities such as landing from a jump, or the foot strike phase of gait deserves further study. © 2006 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 24:516,523, 2006 [source] A biomechanical study on flexible intramedullary nails used to treat pediatric femoral fracturesJOURNAL OF ORTHOPAEDIC RESEARCH, Issue 6 2005Jason K. Green Abstract Flexible intramedullary nails have been indicated to treat femoral fractures in pediatric patients. The purpose of this study was to examine the stability of simulated transverse fractures after retrograde intramedullary flexible nail fixation. Various nail diameter combinations were tested using composite femurs in bending, torsion, and a combined axial/bending test where a vertical compressive force was applied to the femoral head. The cross-sectional percent area fill of the nails within the femurs was also determined. In 4 point bending, the greatest repair stiffness was 12% of the intact stiffness. In torsion, the greatest stiffness was 1% of the intact stiffness for either internal or external rotation. The greatest repair stiffness was 80% of the intact stiffness for a compressive load applied to the femoral head. Nail combinations with single nail diameters greater than 40% of the mid-shaft canal width, as measured from an AP radiograph, prevented the fracture from being reduced and left a posterior gap. Flexible intramedullary nails may be of value in the treatment of pediatric femoral fractures, but care must be taken to insert nails that are correctly sized for the canal and to protect the healing fracture from high torsional and bending loads. © 2005 Orthopaedic Research Society. Published by Elsevier Ltd. All rights reserved. [source] Fracture Resistance of Endodontically Treated Teeth: Three Walls versus Four Walls of Remaining Coronal Tooth StructureJOURNAL OF PROSTHODONTICS, Issue 1 2009Siriporn Arunpraditkul DDS Abstract Purpose: The purpose of this study was to evaluate the fracture resistance of endodontically treated teeth between those with four walls and those with three walls of remaining coronal tooth structure and the effect of the site of the missing coronal wall. Materials and Methods: Thirty-two endodontically treated second mandibular premolars were decoronated, leaving 3 mm above the cementoenamel junction (CEJ). A 0.5-mm-wide chamfer was prepared 1 mm above the CEJ. The teeth were randomly divided into four groups. Group 1 had four walls of coronal tooth structure, whereas groups 2, 3, and 4 had only three walls, missing the buccal, lingual, and mesial wall, respectively. The cast dowel and cores and crowns (Ni,Cr alloy) were cemented with zinc phosphate cement. A compressive load was applied 45° to the long axis, 2 mm below the buccal cusp, with an Instron machine until failure at a crosshead speed of 5 mm/min. Failure load (kg) and mode of failure were recorded. Data were analyzed with one-way ANOVA and Scheffé tests (p < 0.05). Results: Group 1 had the highest fracture resistance (1190.3 ± 110.5 kg), significantly different from the other groups (p < 0.05) (group 2: 578.5 ± 197.4 kg; group 3: 786.6 ± 132.8 kg; group 4: 785.4 ± 289.9 kg). There were no significant differences among the test groups. The mode of failure in group 1 was a horizontal root fracture, whereas that of the other groups was either vertical or oblique fracture. Conclusions: Teeth with four walls of remaining coronal dentine had significantly higher fracture resistance than teeth with only three walls. The site of the missing coronal wall did not affect the fracture resistance of endodontically treated teeth. [source] Failure Modes with Point Loading of Three Commercially Available Denture TeethJOURNAL OF PROSTHODONTICS, Issue 6 2008Andrew R. Moffitt DDS Abstract Purpose: A common problem associated with implant-supported prostheses is the fracture of denture teeth. This study was designed to compare the fracture modes of three denture teeth by compressive load at a 30° off-axis angle. Material and Methods: Three denture teeth (Vident Duostat, Ivoclar Vivadent, and Dentsply Trubyte) processed to two denture base processing systems [injection-molded (IM) SR-Ivocap system and compression-molded (CM) denture base resin] were evaluated. Each specimen was processed to a metal framework. Ultimate failure strength of each system when point loaded at a 30° off-axis angle was recorded, along with a visual inspection of each specimen. Results: The average load fracture for each group was (in N): Vident CM 1106.97 ± 223.20, Vident IM 1168.18 ± 322.52, Dentsply CM 1098.08 ± 286.32, Dentsply IM 1023.80 ± 282.45, Ivoclar CM 1616.98 ± 204.87, and Ivoclar IM 1373.54 ± 282.58. There was a significant difference between the groups and the Ivoclar CM group. The Ivoclar CM group had the highest average load force, and the Dentsply IM group had the lowest average load force. On average, the teeth within the groups fractured at a higher compression force than the average maximum occlusal force in natural dentition. Dentsply and Vident denture teeth fractured more horizontally, and the Ivoclar denture teeth fractured more vertically within the groups. There was no significant difference among the groups between the IM and CM processing methods. Conclusions: In the present in vitro study, all specimens were able to withstand 30° off-axis loading with the exception of one specimen. With these results, this would indicate that these denture teeth are able to withstand normal occlusal forces. [source] Effect of synthesis process on the Young's modulus of titanate nanowirePHYSICA STATUS SOLIDI (A) APPLICATIONS AND MATERIALS SCIENCE, Issue 2 2010Ming Chang Abstract Nanocrystalline materials have attracted a great deal of attention because of their intriguing size-/shape-dependent properties. Titanate nanowires have been synthesized from titania (TiO2) nanoparticles using conventional hydrothermal process. Young's moduli of as-prepared titanate nanowires have been determined in situ from the buckling instability of the nanowires due to application of axial compressive load using a nanomanipulator inside a scanning electron microscope. Based on Euler's buckling model, the Young's moduli of the nanowires are determined to be 32,±,11,GPa. The obtained Young's moduli have been compared to that of the titanate nanowires prepared with microwave hydrothermal process to study the effect of synthesis process on the mechanical behavior of nanomaterials. The prolonged holding time of a conventional hydrothermal process helps in the significant enhancement of the Young's modulus of nanowire in comparison to that prepared with microwave hydrothermal process. [source] Mechanics of Aluminum Foam-Polymer HybridADVANCED ENGINEERING MATERIALS, Issue 9 2008K. Stöbener Aluminium foam , polymer hybrids set-up from small volume spherical aluminium foam elements joined by adhesive bonding were subjected to uniaxial compressive loads. Deformation patterns are displayed and discussed. The influence of foam element volume and density as well as strength of polymer joints on the hybrid's mechanical properties are outlined. A simplifying model for prediction of the hybrid's deformation properties is developed and discussed. [source] Habitual use of the primate forelimb is reflected in the material properties of subchondral bone in the distal radiusJOURNAL OF ANATOMY, Issue 6 2006Kristian J. Carlson Abstract Bone mineral density is directly proportional to compressive strength, which affords an opportunity to estimate in vivo joint load history from the subchondral cortical plate of articular surfaces in isolated skeletal elements. Subchondral bone experiencing greater compressive loads should be of relatively greater density than subchondral bone experiencing less compressive loading. Distribution of the densest areas, either concentrated or diffuse, also may be influenced by the extent of habitual compressive loading. We evaluated subchondral bone in the distal radius of several primates whose locomotion could be characterized in one of three general ways (quadrupedal, suspensory or bipedal), each exemplifying a different manner of habitual forelimb loading (i.e. compression, tension or non-weight-bearing, respectively). We employed computed tomography osteoabsorptiometry (CT-OAM) to acquire optical densities from which false-colour maps were constructed. The false-colour maps were used to evaluate patterns in subchondral density (i.e. apparent density). Suspensory apes and bipedal humans had both smaller percentage areas and less well-defined concentrations of regions of high apparent density relative to quadrupedal primates. Quadrupedal primates exhibited a positive allometric effect of articular surface size on high-density area, whereas suspensory primates exhibited an isometric effect and bipedal humans exhibited no significant relationship between the two. A significant difference between groups characterized by predominantly compressive forelimb loading regimes vs. tensile or non-weight-bearing regimes indicates that subchondral apparent density in the distal radial articular surface distinguishes modes of habitually supporting of body mass. [source] Expression of Acid-Sensing Ion Channel 3 (ASIC3) in Nucleus Pulposus Cells of the Intervertebral Disc Is Regulated by p75NTR and ERK Signaling,JOURNAL OF BONE AND MINERAL RESEARCH, Issue 12 2007Yoshiyasu Uchiyama Abstract Although a recent study has shown that skeletal tissues express ASICs, their function is unknown. We show that intervertebral disc cells express ASIC3; moreover, expression is uniquely regulated and needed for survival in a low pH and hypoeromsotic medium. These findings suggest that ASIC3 may adapt disc cells to their hydrodynamically stressed microenvironment. Introduction: The nucleus pulposus is an avascular, hydrated tissue that permits the intervertebral disc to resist compressive loads to the spine. Because the tissue is hyperosmotic and avascular, the pH of the nucleus pulposus is low. To determine the mechanisms by which the disc cells accommodate to the low pH and hypertonicity, the expression and regulation of the acid sensing ion channel (ASIC)3 was examined. Materials and Methods: Expression of ASICs in cells of the intervertebral disc was analyzed. To study its regulation, we cloned the 2.8-kb rat ASIC3 promoter and performed luciferase reporter assays. The effect of pharmacological inhibition of ASICs on disc cell survival was studied by measuring MTT and caspase-3 activities. Results: ASIC3 was expressed in discal tissues and cultured disc cells in vitro. Because studies of neuronal cells have shown that ASIC3 expression and promoter activity is induced by nerve growth factor (NGF), we examined the effect of NGF on nucleus pulposus cells. Surprisingly, ASIC3 promoter activity did not increase after NGF treatment. The absence of induction was linked to nonexpression of tropomyosin-related kinase A (TrkA), a high-affinity NGF receptor, although a modest expression of p75NTR was seen. When treated with p75NTR antibody or transfected with dominant negative-p75NTR plasmid, there was significant suppression of ASIC3 basal promoter activity. To further explore the downstream mechanism of control of ASIC3 basal promoter activity, we blocked p75NTR and measured phospho extracellular matrix regulated kinase (pERK) levels. We found that DN-p75NTR suppressed NGF mediated transient ERK activation. Moreover, inhibition of ERK activity by dominant negative-mitogen activated protein kinase kinase (DN-MEK) resulted in a dose-dependent suppression of ASIC3 basal promoter activity, whereas overexpression of constitutively active MEK1 caused an increase in ASIC3 promoter activity. Finally, to gain insight in the functional importance of ASIC3, we suppressed ASIC activity in nucleus pulposus cells. Noteworthy, under both hyperosmotic and acidic conditions, ASIC3 served to promote cell survival and lower the activity of the pro-apoptosis protein, caspase-3. Conclusions: Results of this study indicate that NGF serves to maintain the basal expression of ASIC3 through p75NTR and ERK signaling in discal cells. We suggest that ASIC3 is needed for adaptation of the nucleus pulposus and annulus fibrosus cells to the acidic and hyperosmotic microenvironment of the intervertebral disc. [source] Construction of the Femoral Neck During Growth Determines Its Strength in Old Age,JOURNAL OF BONE AND MINERAL RESEARCH, Issue 7 2007Roger M D Zebaze Abstract Study of the design of the FN in vivo in 697 women and in vitro in 200 cross-sections of different sizes and shapes along each of 13 FN specimens revealed that strength in old age was largely achieved during growth by differences in the distribution rather than the amount of bone material in a given FN cross-section from individual to individual. Introduction: We studied the design of the femoral neck (FN) to gain insight into the structural basis of FN strength in adulthood and FN fragility in old age. Materials and Methods: Studies in vivo were performed using densitometry in 697 women and in vitro using high-resolution ,CT and direct measurements in 13 pairs of postmortem specimens. Results: The contradictory needs of strength for loading yet lightness for mobility were met by varying FN size, shape, spatial distribution, and proportions of its trabecular and cortical bone in a cross-section, not its mass. Wider and narrower FNs were constructed with similar amounts of bone material. Wider FNs were relatively lighter: a 1 SD higher FN volume had a 0.67 (95% CI, 0.61,0.72) SD lower volumetric BMD (vBMD). A 1 SD increment in height was achieved by increasing FN volume by 0.32 (95% CI, 0.25,0.39) SD with only 0.15 (95% CI, 0.08,0.22) SD more bone, so taller individuals had a relatively lighter FN (vBMD was 0.13 [95% CI, 0.05,0.20 SD] SD lower). Greater periosteal apposition constructing a wider FN was offset by even greater endocortical resorption so that the same net amount of bone was distributed as a thinner cortex further from the neutral axis, increasing resistance to bending and lowering vBMD. This was recapitulated at each point along the FN; varying absolute and relative degrees of periosteal apposition and endocortical resorption focally used the same amount of material to fashion an elliptical FN of mainly cortical bone near the femoral shaft to offset bending but a more circular FN of proportionally more trabecular and less cortical bone to accommodate compressive loads adjacent to the pelvis. This structural heterogeneity was largely achieved by adaptive modeling and remodeling during growth,most of the variance in FN volume, BMC, and vBMD was growth related. Conclusions: Altering structural design while minimizing mass achieves FN strength and lightness. Bone fragility may be the result of failure to adapt bone's architecture to loading, not just low bone mass. [source] Joint compression alters the kinematics and loading patterns of the intact and capsule-transected AC jointJOURNAL OF ORTHOPAEDIC RESEARCH, Issue 3 2003Ryan S. Costic High compressive loads are transmitted through the shoulder across the acromioclavicular (AC) joint to the axial skeleton during activities of daily living and can lead to early joint degeneration or instability. The objective of this study was to quantify the effect of joint compression on the biomechanics of the intact and capsule-transected AC joint during application of three loading conditions. A robotic/universal force-moment sensor testing system was utilized to apply an anterior, posterior or superior load of 70 N in combination with 10 or 70 N of joint compression to fresh-frozen cadaveric shoulders (n = 12). The application of joint compression to the intact AC joint decreased the posterior translation in response to a posterior load (,6.6 ± 2.5 vs ,3.7 ± 1.0 mm, p<0.05). Joint compression also decreased the in situ force in the superior AC capsule by 10 N while increasing the joint contact force by 20 N for all loading conditions (p<0.05). The application of joint compression to the capsule-transected AC joint significantly decreased the amount of posterior and superior translation during posterior (,12.7 ± 6.1 vs ,5.5 ± 3.2 mm, p < 0.05) and superior (5.3 ± 2.9 vs 4.2 ± 2.3 mm, p < 0.05) loading, respectively, while significantly increasing the coupled translations (anterior,posterior, superior,inferior or proximal,distal) in all loading conditions (p < 0.05). The joint contact force also significantly increased by 20 N for all loading conditions (p < 0.05). This quantitative data suggests: (1) common surgical techniques such as distal clavicle resection, which initially reduce painful joint contact, may cause unusually high loads to be supported by the soft tissue structures at the AC joint; and (2) compressive loads transmitted across a capsule-transected AC joint could be concentrated over a smaller area due to the increased coupled motion and joint contact force. © 2002 Orthopaedic Research Society. Published by Elsevier Science Ltd. All rights reserved. [source] Novel ceramic bone replacement material CeraBall® seeded with human mesenchymal stem cellsCLINICAL ORAL IMPLANTS RESEARCH, Issue 3 2010Timothy Douglas Abstract Objectives: Hydroxyapatite (HA) and tricalcium phosphate (TCP) are two very common ceramic materials for bone replacement. A recently developed material for bone replacement is CeraBall®, which is a mixed HA,TCP scaffold available as porous spherical scaffolds of diameter 4 and 6 mm. Before their use as bone replacement materials in vivo, in vitro testing of these scaffolds is necessary. The goal of this study was to characterise 4 and 6 mm CeraBall® scaffolds in vitro with a view to their future use as bone replacement materials. Materials and methods: The proliferation of human mesenchymal stromal cells (hMSCs) seeded on CeraBall® scaffolds was evaluated quantitatively using the WST [Water soluble tetrazolium ((4-[3-(4- Iodophenyl)-2-(4-nitrophenyl)-2H-5-tetrazolio]-1, 3-benzene disulfonate)] test and qualitatively by scanning electron microscopy (SEM). In addition, the standard MTT [(3-(4, 5-Dimenthylthiazol-2-Y1)-2, 5-Diphenyltetrazolium bromide)] biocompatibility test and cell vitality staining were performed using hMSCs. CeraBall® scaffolds were also tested for their mechanical properties. Results: SEM and WST test results showed that hMSCs proliferated on CeraBall® scaffolds over the course of 9 days. Proliferation was similar to that seen on tissue culture polystyrene (control). Cells showed a well-spread morphology and formed ,sheets' on the surface of scaffolds. Invasion of pores was observed. Good biocompatibility was demonstrated by MTT test results and cell vitality staining. Scaffolds of both 4 and 6 mm were able to withstand compressive loads of 5 N. Conclusions: CeraBall® scaffolds show good biocompatibility in vitro for hMSCs. This opens the way for in vivo applications. To cite this article: Douglas T, Liu Q, Humpe A, Wiltfang J, Sivananthan S, Warnke PH. Novel ceramic bone replacement material CeraBall® seeded with human mesenchymal stem cells. Clin. Oral Impl. Res. 21, 2010; 262,267. doi: 10.1111/j.1600-0501.2009.01818.x [source] |