Common Component (common + component)

Distribution by Scientific Domains


Selected Abstracts


Common components and specific weight analysis and multiple co-inertia analysis applied to the coupling of several measurement techniques

JOURNAL OF CHEMOMETRICS, Issue 5 2006
M. Hanafi
Abstract The present paper compares two multiblock techniques: the Common Components and Specific Weights Analysis (CCSWA) and the Multiple Co-inertia Analysis (MCoA). Both methods are used to (1) to investigate the relationships among various data tables and (2) to extract latent variables from information of different nature, reflecting different facets of a food product. Our objective is to study the ability of these methods to extract, from a set of data tables, latent characteristics which are representative of the whole modifications brought to a complex system (food product) by a modification of a given process factor. The comparison of these methods is based on the investigation of their conceptual framework by particularly highlighting new properties of CCSWA. Moreover, the two techniques of analysis are compared on the basis of a case study in cheese processing where each cheese sample is described by different kinds of measurements. Copyright © 2007 John Wiley & Sons, Ltd. [source]


First record of the brachiopod Lingulella waptaensis with pedicle from the Middle Cambrian Burgess Shale

ACTA ZOOLOGICA, Issue 2 2010
Sandra Pettersson Stolk
Abstract Pettersson Stolk, S., Holmer, L. E. and Caron, J -B. 2010. First record of the brachiopod Lingulella waptaensis with pedicle from the Middle Cambrian Burgess Shale. ,Acta Zoologica (Stockholm) 91: 150,162 The organophosphatic shells of linguloid brachiopods are a common component of normal Cambrian,Ordovician shelly assemblages. Preservation of linguloid soft-part anatomy, however, is extremely rare, and restricted to a few species in Lower Cambrian Konservat Lagerstätten. Such remarkable occurrences provide unique insights into the biology and ecology of early linguloids that are not available from the study of shells alone. Based on its shells, Lingulella waptaensis Walcott, was originally described in 1924 from the Middle Cambrian Burgess Shale but despite the widespread occurrence of soft-part preservation associated with fossils from the same levels, no preserved soft parts have been reported. Lingulella waptaensis is restudied herein based on 396 specimens collected by Royal Ontario Museum field parties from the Greater Phyllopod Bed (Walcott Quarry Shale Member, British Columbia). The new specimens, including three with exceptional preservation of the pedicle, were collected in situ in discrete obrution beds. Census counts show that L. waptaensis is rare but recurrent in the Greater Phyllopod Bed, suggesting that this species might have been generalist. The wrinkled pedicle protruded posteriorly between the valves, was composed of a central coelomic space, and was slender and flexible enough to be tightly folded, suggesting a thin chitinous cuticle and underlying muscular layers. The nearly circular shell and the long, slender and highly flexible pedicle suggest that L. waptaensis lived epifaunally, probably attached to the substrate. Vertical cross-sections of the shells show that L. waptaensis possessed a virgose secondary layer, which has previously only been known from Devonian to Recent members of the Family Lingulidae. [source]


Cloning and characterisation of a prenyltransferase from the aphid Myzus persicae with potential involvement in alarm pheromone biosynthesis

INSECT MOLECULAR BIOLOGY, Issue 4 2008
M. J. Lewis
Abstract The majority of aphid species release an alarm pheromone with the most common component being the sesquiterpene (E)-,-farnesene, sometimes accompanied by other sesquiterpenes or monoterpenes. The genes/enzymes involved in the production of these compounds have not been identified in aphids although some components of isoprenoid biosynthesis have been identified in other insect species. Here we report the cloning, expression and characterisation of a prenyltransferase from the aphid Myzus persicae which can act as a farnesyl pyrophosphate synthase or a geranyl pyrophosphate synthase to produce both sesquiterpenes and monoterpenes and hence could be responsible for the biosynthesis of the observed components of the alarm pheromones. In addition, the enzyme can utilise geranyl pyrophosphate to produce farnesyl pyrophosphate showing that the synthesis of the latter involves the sequential condensation of isoprenyl pyrophosphate units. [source]


Isotopic tracking of prehistoric pinniped foraging and distribution along the central California coast: preliminary results

INTERNATIONAL JOURNAL OF OSTEOARCHAEOLOGY, Issue 1 2002
R. K. Burton
Abstract Zooarchaeological data from Monterey Bay and the adjacent central California coast corroborate earlier observations from northern California and Oregon that Callorhinus ursinus (northern fur seal) was a much more common component in prehistoric marine mammal prey than its present pelagic distribution and foraging habits would predict. C. ursinus remains from mid-Holocene Monterey Bay occurrences are predominantly from female individuals, associated with an inshore piscifauna, and lack associated artifactual evidence for deep water exploitation. Taken together with evidence from Oregon, this suggests that mid-Holocene C. ursinus populations had different foraging, resting, and, arguably, reproductive behaviours than historically reported. Currently debated is whether the contrast between prehistoric and present patterns of pinniped species representation results from: 1) late Holocene prehistoric resource depression by aboriginal hunters, 2) depredations of the early historic fur trade, or 3) non-anthropogenic climatic or oceanographic change. The issue has thus far been addressed with presence or absence data on pinniped species and age/sex classes in dated contexts. While these are fundamental data, they cannot shed light on the nature of foraging behaviour of the species in question, a key dimension of the problem. This paper reports a pilot study utilizing stable isotope analysis aimed to elucidate prehistoric pinniped foraging patterns, specifically that of C. ursinus. Elements from six archaeological sites in Monterey and Santa Cruz counties were analysed for stable isotope compositions of carbon and nitrogen in bone collagen and compared to a latitudinally ordered modern dataset. Results for archaeological C. ursinus strongly suggest that prehistoric animals habitually foraged at lower latitudes than characterize the species today, supporting earlier claims of their year-round residency south of Alaska. Copyright © 2002 John Wiley & Sons, Ltd. [source]


Carotenoid coloration in great black-backed gull Larus marinus reflects individual quality

JOURNAL OF AVIAN BIOLOGY, Issue 1 2006
Kai O. Kristiansen
Carotenoids are a large group of biochemicals, with similar properties, synthesised by bacteria, fungi, algae and plants. Vertebrates obtain these biologically active pigments through the diet, and they are a disproportionately common component of animal colour signals and play important roles in immune functions and as antioxidants. Carotenoids are believed to be a limited resource and because of the trade-off between allocation of carotenoids to signals and to other functions, carotenoid based signals are often thought to be handicap signals. The purpose of this study was to investigate the signalling potential of carotenoid-based tissue coloration in the great black-backed gull Larus marinus. The intensity of carotenoid-based coloration in bill, gape and eye-ring coloration was investigated in relation to body condition, reproductive parameters, levels of immune activity, and sexual dimorphism. In males there was a positive relationship between colour intensity and body condition, but in females no such relationship was found. However, females with high colour intensity had larger eggs and clutches. Additionally, females with high red scores tended to have high density of circulating lymphocytes. There was no sexual dimorphism in coloration and there was a negative relationship between colour intensity and sampling time, which indicates that this coloration is most intensely expressed early in the breeding season. The results in this study suggest that carotenoid-based coloration in great black-backed gull are partly condition dependent and reveal information about individual quality in both males an females. Hence, it might have evolved as an important signal for assessing the quality of potential mates. [source]


Mentoring relationships for youth: Investigation of a process-oriented model

JOURNAL OF COMMUNITY PSYCHOLOGY, Issue 4 2002
Gilbert R. Parra
We investigated a process-oriented model of mentoring using data on 50 relationships in a Big Brothers/Big Sisters program. Data were collected on a monthly basis from both mentors and youth over a one-year period; relationship benefits for youth were assessed at the end of the year by each type of informant. The degree to which relationships were continued throughout the one-year period also was assessed. Path analyses using both youth and mentor report data revealed relations among study variables consistent with the proposed model. Mentors' ratings of their efficacy, obtained prior to the start of relationships, predicted greater amounts of mentor/youth contact as well as more positive experiences in relationships (e.g., fewer obstacles). Feelings of closeness between mentors and youth, in turn, were a final common component in model pathways that linked mentor/youth contact and most other measures to greater perceived benefits and relationship continuation. Implications for the design and evaluation of mentoring programs for youth are discussed. © 2002 Wiley Periodicals, Inc. [source]


Pseudo-maple syrup urine disease due to maternal prenatal ingestion of fenugreek

JOURNAL OF PAEDIATRICS AND CHILD HEALTH, Issue 4 2001
SH Korman
Abstract: Fenugreek, maple syrup and the urine of maple syrup urine disease (MSUD) patients all share a characteristic odour originating from a common component, sotolone. Ingestion of fenugreek by mothers during labour resulted in a maple syrup-like odour in their newborn infants, leading to a false suspicion of MSUD. [source]


PRODUCTION AND RELEASE OF GEOSMIN BY THE CYANOBACTERIUM OSCILLATORIA SPLENDIDA ISOLATED FROM A PHOENIX WATER SOURCE

JOURNAL OF PHYCOLOGY, Issue 2001
Article first published online: 24 SEP 200
Hu, Q.1, Sommerfeld, M.1 Lowry, D.1, Dempster, T.1, Westerhoff, P.2, Baker, L.3, Bruce, D. & Nguyen, M. L.2 1Department of Plant Biology and 2Department of Civil and Environmental Engineering, Arizona State University, Tempe, Arizona 85287; 3Baker Environmental Consulting, 8001 Greenwood Drive, Moundview, MN 55112 Geosmin is a common component of the off-flavors detected in the drinking water supply sources of metropolitan Phoenix (Arizona). A cyanobacterium, Oscillatoria splendida, was isolated from source water during incidents of elevated geosmin production and was implicated as a cause of earthy/musty off-flavors in the drinking water. Production of geosmin was found to be constitutive in O. splendida during all growth stages. Effects of environmental parameters on the growth characteristics, and on production and release of geosmin by O. splendida, was studied under laboratory conditions. The specific growth rate and cell-bound geosmin increased with increasing temperature from 12 to 26 °C, the range of water temperatures that occur in the drinking water supply. On a per-chlorophyll a basis, however, more geosmin was released from the cells at lower temperatures. An inverse relationship was evident between light intensity and O. splendida growth and the release of geosmin. Cell-bound geosmin, however, was higher at higher light intensities. Dark incubation initially stimulated the biosynthesis of geosmin, whereas a prolonged period of darkness (2-3 weeks) resulted in massive release of geosmin into the culture medium from lysis and cellular decomposition. Dissolved nitrogen appeared to be the limiting nutrient for O. splendida in the local water supply source. When nitrate was added to laboratory cultures, both growth and geosmin production increased. These results will be discussed in context with episodes of off-flavors in drinking waters in metropolitan Phoenix, Arizona. [source]


Regional Labour Market Adjustment: Are Positive and Negative Shocks Different?

LABOUR, Issue 2 2002
Sari Pekkala
This paper analyses regional labour market adjustment in the Finnish provinces during 1971,96. It investigates the interrelations of employment, unemployment and labour force participation to examine how a change in labour demand is adjusted to. The study questions the usual assumption that positive and negative shocks evoke similar adjustment processes. Instead, we test for the possibility that the effects of positive and negative shocks are asymmetric. The analysis reveals that there is little asymmetry in the adjustment to region-specific labour demand shocks, but adjustment to total (region-specific plus common component) shocks displays more asymmetry. The region-specific component of a labour demand shock has short-lived effects on unemployment and participation, and its effect on employment is very small but permanent [persistent?]. Initially, most of the fall in employment is absorbed by the unemployment and participation rate, but after a few years migration plays a larger role in the adjustment process. [source]


Functional analysis of the large periplasmic loop of the Escherichia coli K-12 WaaL O-antigen ligase

MOLECULAR MICROBIOLOGY, Issue 6 2008
José M. Pérez
Summary WaaL is a membrane enzyme implicated in ligating undecaprenyl-diphosphate (Und-PP)-linked O antigen to lipid A-core oligosaccharide. We determined the periplasmic location of a large (EL5) and small (EL4) adjacent loops in the Escherichia coli K-12 WaaL. Structural models of the EL5 from the K-12, R1 and R4 E. coli ligases were generated by molecular dynamics. Despite the poor amino acid sequence conservation among these proteins, the models afforded similar folds consisting of two pairs of almost perpendicular ,-helices. One ,-helix in each pair contributes a histidine and an arginine facing each other, which are highly conserved in WaaL homologues. Mutations in either residue rendered WaaL non-functional, since mutant proteins were unable to restore O antigen surface expression. Replacements of residues located away from the putative catalytic centre and non-conserved residues within the centre itself did not affect ligation. Furthermore, replacing a highly conserved arginine in EL4 with various amino acids inactivates WaaL function, but functionality reappears when the positive charge is restored by a replacement with lysine. These results lead us to propose that the conserved amino acids in the two adjacent periplasmic loops could interact with Und-PP, which is the common component in all WaaL substrates. [source]


Fluctuations in isometric muscle force can be described by one linear projection of low-frequency components of motor unit discharge rates

THE JOURNAL OF PHYSIOLOGY, Issue 24 2009
Francesco Negro
The aim of the study was to investigate the relation between linear transformations of motor unit discharge rates and muscle force. Intramuscular (wire electrodes) and high-density surface EMG (13 × 5 electrode grid) were recorded from the abductor digiti minimi muscle of eight healthy men during 60 s contractions at 5%, 7.5% and 10% of the maximal force. Spike trains of a total of 222 motor units were identified from the EMG recordings with decomposition algorithms. Principal component analysis of the smoothed motor unit discharge rates indicated that one component (first common component, FCC) described 44.2 ± 7.5% of the total variability of the smoothed discharge rates when computed over the entire contraction interval and 64.3 ± 10.2% of the variability when computed over 5 s intervals. When the FCC was computed from four or more motor units per contraction, it correlated with the force produced by the muscle (62.7 ± 10.1%) by a greater degree (P < 0.001) than the smoothed discharge rates of individual motor units (41.4 ± 7.8%). The correlation between FCC and the force signal increased up to 71.8 ± 13.1% when the duration and the shape of the smoothing window for discharge rates were similar to the average motor unit twitch force. Moreover, the coefficients of variation (CoV) for the force and for the FCC signal were correlated in all subjects (R2 range = 0.14,0.56; P < 0.05) whereas the CoV for force was correlated to the interspike interval variability in only one subject (R2= 0.12; P < 0.05). Similar results were further obtained from measures on the tibialis anterior muscle of an additional eight subjects during contractions at forces up to 20% of the maximal force (e.g. FCC explained 59.8 ± 11.0% of variability of the smoothed discharge rates). In conclusion, one signal captures most of the underlying variability of the low-frequency components of motor unit discharge rates and explains large part of the fluctuations in the motor output during isometric contractions. [source]


FUS-immunoreactive inclusions are a common feature in sporadic and non-SOD1 familial amyotrophic lateral sclerosis

ANNALS OF NEUROLOGY, Issue 6 2010
Han-Xiang Deng MD
Objective Amyotrophic lateral sclerosis (ALS) is a fatal disorder of motor neuron degeneration. Most cases of ALS are sporadic (SALS), but about 5 to 10% of ALS cases are familial (FALS). Recent studies have shown that mutations in FUS are causal in approximately 4 to 5% of FALS and some apparent SALS cases. The pathogenic mechanism of the mutant FUS-mediated ALS and potential roles of FUS in non-FUS ALS remain to be investigated. Methods Immunostaining was performed on postmortem spinal cords from 78 ALS cases, including SALS (n = 52), ALS with dementia (ALS/dementia, n = 10), and FALS (n = 16). In addition, postmortem brains or spinal cords from 22 cases with or without frontotemporal lobar degeneration were also studied. In total, 100 cases were studied. Results FUS-immunoreactive inclusions were observed in spinal anterior horn neurons in all SALS and FALS cases, except for those with SOD1 mutations. The FUS-containing inclusions were also immunoreactive with antibodies to TDP43, p62, and ubiquitin. A fraction of tested FUS antibodies recognized FUS inclusions, and specific antigen retrieval protocol appeared to be important for detection of the skein-like FUS inclusions. Interpretation Although mutations in FUS account for only a small fraction of FALS and SALS, our data suggest that FUS protein may be a common component of the cellular inclusions in non-SOD1 ALS and some other neurodegenerative conditions, implying a shared pathogenic pathway underlying SALS, non-SOD1 FALS, ALS/dementia, and related disorders. Our data also indicate that SOD1-linked ALS may have a pathogenic pathway distinct from SALS and other types of FALS. ANN NEUROL 2010;67:739,748 [source]


Linkages between Trade and Financial Integration and Output Growth in East Asia

ASIAN ECONOMIC JOURNAL, Issue 1 2010
Maria Socorro Gochoco-Bautista
E32; F42; F43 The effects of trade, financial and other variables generally seen as indicative of the degree of economic integration on movements in industrial production growth among countries in East Asia are assessed using the common component of movements in industrial production growth in the ASEAN 5 + 3 countries as a business cycle benchmark for the region. The results show the dominance of trade-related variables, as well as the world price of oil, in driving regional industrial production growth. Financial variables, while important, are not as robust. [source]


Removal of endogenous retrovirus-like particles from CHO-cell derived products using Q sepharose fast flow chromatography,

BIOTECHNOLOGY PROGRESS, Issue 4 2009
Daniel M. Strauss
Abstract Retrovirus-like particles (RVLPs) that are expressed during the production of monoclonal antibodies in Chinese hamster ovary (CHO) cell cultures must be removed during product recovery. Anion exchange chromatography (AEX) performed in product flow-through mode, a common component in the purification of monoclonal antibodies, has been shown to provide robust removal of a related retrovirus model, but it's ability to remove the actual RVLP impurities has not been directly investigated. We have determined the ability of a typical Q sepharose process to remove actual CHO RVLP impurities. Using small scale experiments with three model antibodies, we observe that this AEX process is capable of effectively removing both in-process and spiked RVLPs from different feedstocks containing different mAb products. In addition, we show that this AEX process also achieves a similarly high degree of RVLP removal during large scale manufacturing operations. © 2009 American Institute of Chemical Engineers Biotechnol. Prog., 2009 [source]


Prevalence of the metabolic syndrome in elementary school children

ACTA PAEDIATRICA, Issue 8 2006
Katrina D. Dubose
Abstract Aim: To determine the prevalence of the metabolic syndrome (MS) and its related components in elementary-aged school children. Methods: Three hundred and seventy-five 7,9-y-old boys (n=182) and girls (n=193) in the eastern Kansas area served as participants. Criteria for the MS were the presence of three or more of the following components: 1) central obesity (waist circumference ,90th percentile in males and females); 2) elevated triglyceride concentrations (,1.13 mmol/l); 3) low HDL-C concentrations (,1.04 mmol/l in males and females); 4) elevated blood pressure (systolic and/or diastolic ,90th percentile, age and gender specific); or 5) elevated fasting glucose levels (,6.10 mmol/l). Results: The prevalence of the MS in this sample was 5%, and was similar across gender and race. Fifty percent of the children had no components and 15% had at least two components, with elevated blood pressure the most common component (37%). Conclusion: The MS is prevalent even in young children at rates similarly reported in adolescents. [source]


Insulin resistance and the metabolic syndrome in obese French children

CLINICAL ENDOCRINOLOGY, Issue 6 2006
Céline Druet
Summary Objective, To estimate the frequency of the metabolic syndrome (MS) and of the insulin resistance syndrome (IRS) in overweight or obese French children and to determine the risk factors. Design, patients and methods, A total of 308 overweight and obese children [166 girls, 142 boys, aged 7,17 years; median body mass index (BMI) 4·7 standard deviation (SD) (Q1,Q3: 3·9,5·8) adjusted for age and sex] were included. The frequency of the MS was assessed with the National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP III) criteria and the frequency of the IRS with World Health Organization (WHO) criteria. Results, The overall frequency of MS and IRS was 15·9% and 42·5%, respectively. The most common component, after abdominal obesity (95·8%) and IR (71·8%), was elevated systolic blood pressure (28·6%). The frequency of glucose tolerance disorders was low (3·6%). The frequency of MS was independently influenced by homeostatic model assessment (HOMA) (P = 0·06) and waist-to-hip ratio (P = 0·09), whereas the frequency of IRS was influenced by adiposity (degree of obesity: P = 0·02; waist-to-hip ratio: P = 0·05), puberty (P = 0·05) and mother's BMI (P = 0·01). Ethnicity had no effect on either MS or IRS. Conclusions, Metabolic complications and IR are frequent in overweight and obese children whereas the frequency of glucose tolerance disorders is very low. IRS is more prevalent than MS, indicating a major role of IR, which could precede the other metabolic complications in obese children. IRS is a relevant marker for the risk of type 2 diabetes (T2D) and cardiovascular complications in obese European children. [source]


Life, information, entropy, and time: Vehicles for semantic inheritance

COMPLEXITY, Issue 1 2007
Antony R. Crofts
Abstract Attempts to understand how information content can be included in an accounting of the energy flux of the biosphere have led to the conclusion that, in information transmission, one component, the semantic content, or "the meaning of the message," adds no thermodynamic burden over and above costs arising from coding, transmission and translation. In biology, semantic content has two major roles. For all life forms, the message of the genotype encoded in DNA specifies the phenotype, and hence the organism that is tested against the real world through the mechanisms of Darwinian evolution. For human beings, communication through language and similar abstractions provides an additional supra-phenotypic vehicle for semantic inheritance, which supports the cultural heritages around which civilizations revolve. The following three postulates provide the basis for discussion of a number of themes that demonstrate some important consequences. (i) Information transmission through either pathway has thermodynamic components associated with data storage and transmission. (ii) The semantic content adds no additional thermodynamic cost. (iii) For all semantic exchange, meaning is accessible only through translation and interpretation, and has a value only in context. (1) For both pathways of semantic inheritance, translational and copying machineries are imperfect. As a consequence both pathways are subject to mutation and to evolutionary pressure by selection. Recognition of semantic content as a common component allows an understanding of the relationship between genes and memes, and a reformulation of Universal Darwinism. (2) The emergent properties of life are dependent on a processing of semantic content. The translational steps allow amplification in complexity through combinatorial possibilities in space and time. Amplification depends on the increased potential for complexity opened by 3D interaction specificity of proteins, and on the selection of useful variants by evolution. The initial interpretational steps include protein synthesis, molecular recognition, and catalytic potential that facilitate structural and functional roles. Combinatorial possibilities are extended through interactions of increasing complexity in the temporal dimension. (3) All living things show a behavior that indicates awareness of time, or chronognosis. The ,4 billion years of biological evolution have given rise to forms with increasing sophistication in sensory adaptation. This has been linked to the development of an increasing chronognostic range, and an associated increase in combinatorial complexity. (4) Development of a modern human phenotype and the ability to communicate through language, led to the development of archival storage, and invention of the basic skills, institutions and mechanisms that allowed the evolution of modern civilizations. Combinatorial amplification at the supra-phenotypical level arose from the invention of syntax, grammar, numbers, and the subsequent developments of abstraction in writing, algorithms, etc. The translational machineries of the human mind, the "mutation" of ideas therein, and the "conversations" of our social intercourse, have allowed a limited set of symbolic descriptors to evolve into an exponentially expanding semantic heritage. (5) The three postulates above open interesting epistemological questions. An understanding of topics such dualism, the élan vital, the status of hypothesis in science, memetics, the nature of consciousness, the role of semantic processing in the survival of societies, and Popper's three worlds, require recognition of an insubstantial component. By recognizing a necessary linkage between semantic content and a physical machinery, we can bring these perennial problems into the framework of a realistic philosophy. It is suggested, following Popper, that the ,4 billion years of evolution of the biosphere represents an exploration of the nature of reality at the physicochemical level, which, together with the conscious extension of this exploration through science and culture, provides a firm epistemological underpinning for such a philosophy. © 2007 Wiley Periodicals, Inc. Complexity, 2007 [source]


POPULATION DIFFERENTIATION IN THE BEETLE TRIBOLIUM CASTANEUM.

EVOLUTION, Issue 3 2007

We used joint-scaling analyses in conjunction with rearing temperature variation to investigate the contributions of additive, non-additive, and environmental effects to genetic divergence and incipient speciation among 12 populations of the red flour beetle, Tribolium castaneum, with small levels of pairwise nuclear genetic divergence (0.033 < Nei's D < 0.125). For 15 population pairs we created a full spectrum of line crosses (two parental, two reciprocal F1's, four F2's, and eight backcrosses), reared them at multiple temperatures, and analyzed the numbers and developmental defects of offspring. We assayed a total of 219,388 offspring from 5147 families. Failed crosses occurred predominately in F2's, giving evidence of F2 breakdown within this species. In all cases where a significant model could be fit to the data on offspring number, we observed at least one type of digenic epistasis. We also found maternal and cytoplasmic effects to be common components of divergence among T. castaneum populations. In some cases, the most complex model tested (additive, dominance, epistatic, maternal, and cytoplasmic effects) did not provide a significant fit to the data, suggesting that linkage or higher order epistasis is involved in differentiation between some populations. For the limb deformity data, we observed significant genotype-by-environment interaction in most crosses and pure parent crosses tended to have fewer deformities than hybrid crosses. Complexity of genetic architecture was not correlated with either geographic distance or genetic distance. Our results support the view that genetic incompatibilities responsible for postzygotic isolation, an important component of speciation, may be a natural but serendipitous consequence of nonadditive genetic effects and structured populations. [source]


Fatty acid analyses reveal high degrees of omnivory and dietary plasticity in pond-dwelling tadpoles

FRESHWATER BIOLOGY, Issue 7 2010
MATT R. WHILES
Summary 1.,Understanding the trophic relationships of consumers is central to ecology, but constructing meaningful food webs is often difficult because of a lack of detailed information on consumption versus assimilation and high degrees of omnivory. 2.,We used fatty acid analyses to examine the trophic relationships of three common larval anurans (Pseudacris crucifer, Lithobates catesbeianus and Lithobates clamitans) that are often classified as grazers or detritivores. Tadpoles and potential food sources were sampled in four ponds in southern Illinois and analysed for fatty acid composition. Single linkage cluster analysis was then used to compare fatty acid profiles among tadpole gut contents, tadpole muscle tissues and available food resources. 3.,Diets varied among species and within species among ponds, but organic sediments consistently contributed most to the fatty acid composition of the gut contents of all species. Fatty acid profiles also indicated that larval insects and phytoplankton were consumed by both L. catesbeianus and L. clamitans in one pond, while L. clamitans and P. crucifer consumed mainly periphyton along with sediments in another pond, and these diet differences appeared linked to physical differences among ponds, with periphyton and/or phytoplankton contributing more to tadpole diets in less shaded ponds. 4.,The fatty acid composition of muscle tissues of L. clamitans, the dominant tadpole in these systems, indicated that plant detritus and bacteria, which were the dominant components of organic sediments in the ponds, were common components of the assimilatory diet. 5.,Results demonstrate the utility of fatty acid analyses for assessing both consumption and assimilation. The tadpole assemblages we examined derive much of their energy from heterotrophic and allochthonous sources and exhibit high dietary plasticity. This information will allow for more accurate and comprehensive assessments of trophic interactions in freshwater habitats, as well as aid in amphibian conservation, management and captive propagation efforts. [source]


IPv6 networks over DVB-RCS satellite systems

INTERNATIONAL JOURNAL OF SATELLITE COMMUNICATIONS AND NETWORKING, Issue 1 2008
Ricardo Castellot Lou
Abstract Satellite plays an important role in global information infrastructure (GII) and next generation networks (NGNs). Similarly, satellite communication systems have great advantages to support IPv6 (Internet Protocol version 6) networks as a technology that allows universal access to broadband e-services (audio, video, VPN, etc.). In the context of DVB-S2 (digital video broadcast-satellite) and DVB-RCS (digital video broadcast-return channel via satellite) standards, this paper presents the current SatSix project (satellite-based communications systems within IPv6 networks) within the European 6th Framework Programme, which is implementing innovative concepts and effective solutions (in relation with the economical cost) for broadband satellite systems and services using the technology presented above. This project is promoting the introduction of the IPv6 protocol into satellite-based communication systems. Moreover, through SatSix, the industry is addressing the next generation Internet, IPv6. It also enhances its competitive position in satellite broadband multimedia systems by exploiting the common components defined by the European DVB-S2 and DVB-RCS satellite broadband standards. Copyright © 2007 John Wiley & Sons, Ltd. [source]


Modelling the trend and seasonals within an AIDS model of the demand for alcoholic beverages in the United Kingdom

JOURNAL OF APPLIED ECONOMETRICS, Issue 2 2002
I. A. Moosa
The argument that is put forward in this paper is that failure to represent stochastic trend and stochastic seasonality in an AIDS model leads to a misspecified and possibly structurally unstable model. This proposition is verified by estimating an AIDS model of the demand for alcoholic beverages in the United Kingdom. Three versions of the model are estimated, and it is demonstrated that the version allowing for stochastic trend and stochastic seasonality performs better than the other two versions of the model in terms of the diagnostics tests and goodness of fit measures. The best estimated model turns out to possess the properties of having common components and being homogenous. Further empirical testing reveals the presence of stochastic trends and cointegration between the budget shares of beer and wine. The results clearly indicate that there has been a shift away from the consumption of beer towards wine. Copyright © 2002 John Wiley & Sons, Ltd. [source]


Pharmacological profile of essential oils derived from Lavandula angustifolia and Melissa officinalis with anti-agitation properties: focus on ligand-gated channels

JOURNAL OF PHARMACY AND PHARMACOLOGY: AN INTERNATI ONAL JOURNAL OF PHARMACEUTICAL SCIENCE, Issue 11 2008
Liping Huang
Both Melissa officinalis (Mo) and Lavandula angustifolia (La) essential oils have putative anti-agitation properties in humans, indicating common components with a depressant action in the central nervous system. A dual radioligand binding and electrophysiological study, focusing on a range of ligand-gated ion channels, was performed with a chemically validated essential oil derived from La, which has shown clinical benefit in treating agitation. La inhibited [35S] TBPS binding to the rat forebrain gamma aminobutyric acid (GABA)A receptor channel (apparent IC50 = 0.040 ± 0.001 mg mL,1), but had no effect on N -methyl- d -aspartate (NMDA), alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) or nicotinic acetylcholine receptors. A 50:50 mixture of Mo and La essential oils inhibited [3H] flunitrazepam binding, whereas the individual oils had no significant effect. Electrophysiological analyses with rat cortical primary cultures demonstrated that La reversibly inhibited GABA-induced currents in a concentration-dependent manner (0.01,1 mg mL,1), whereas no inhibition of NMDA- or AMPA-induced currents was noted. La elicited a significant dose-dependent reduction in both inhibitory and excitatory transmission, with a net depressant effect on neurotransmission (in contrast to the classic GABAA antagonist picrotoxin which evoked profound epileptiform burst firing in these cells). These properties are similar to those recently reported for Mo. The anti-agitation effects in patients and the depressant effects of La we report in neural membranes in-vitro are unlikely to reflect a sedative interaction with any of the ionotropic receptors examined here. These data suggest that components common to the two oils are worthy of focus to identify the actives underlying the neuronal depressant and anti-agitation activities reported. [source]


OOGAMOUS REPRODUCTION, WITH TWO-STEP AUXOSPORULATION, IN THE CENTRIC DIATOM THALASSIOSIRA PUNCTIGERA (BACILLARIOPHYTA),

JOURNAL OF PHYCOLOGY, Issue 4 2006
Victor A. Chepurnov
Thalassiosira species are common components of marine planktonic communities worldwide and are used intensively as model experimental organisms. However, data on life cycles and sexuality within the genus are fragmentary. A clone of the cosmopolitan marine diatom Thalassiosira punctigera Cleve emend. Hasle was isolated from the North Sea and oogamous sexual reproduction was observed in culture. Cells approximately 45 ,m and smaller became sexualized. Oogonia were produced preferentially and spermatogenesis was infrequent. Unfertilized oogonia always aborted and their development was apparently arrested at prophase of meiosis I. Further progression through meiosis and auxospore formation occurred only after a sperm had penetrated into the oocyte. Many cells of the new large-celled generation (approximately 90,120 ,m in size) immediately became sexualized again but only oogonia were produced. A few of the large oogonia became auxospores and produced initial cells 132,153 ,m in diameter. The second step of auxosporulation probably involved fertilization of large-celled oocytes by the sperm of the small-celled spermatogonangia that were still present in the culture. An F1 clone obtained after selfing within the small-celled auxosporulation size range was investigated. Like the parent clone, the F1 clone was homothallic but no auxosporulation was observed: spermatogonangia were unable to produce viable sperm, apparently because of inbreeding depression. Aggregation and interaction of oogonia were documented, and may be relevant for understanding the mechanisms of signaling and recognition between sexualized cells and the evolution of sexuality in pennate diatoms. [source]


Learning facilitating factors of teamwork on intellectual capital creation

KNOWLEDGE AND PROCESS MANAGEMENT: THE JOURNAL OF CORPORATE TRANSFORMATION, Issue 1 2005
Juan Gabriel Cegarra-Navarro
In the last few years, a trend has been observed that regards teamwork as a fundamental unit for develop learning processes and other production activities. Group learning is thus the bridge between individual and organizational learning. This paper examines the relative importance and significance of some common components of group learning on ,group capital' (i.e. objective and collective knowledge created by teams) and the effects of such capital on the creation of intellectual capital through an empirical investigation of 139 small to medium-sized enterprises (SMEs) in the Spanish optometry sector using structural equation modelling validated by factor analysis. Copyright © 2005 John Wiley & Sons, Ltd. [source]


The impact of component commonality on composite assembly policies

NAVAL RESEARCH LOGISTICS: AN INTERNATIONAL JOURNAL, Issue 6 2007
Amit Eynan
Abstract Assemble in Advance (AIA) policy reduces assembly cost due to advance planning, while Assemble to Order (ATO) policy eliminates assembly of excessive (more than demanded) units. The tradeoffs between the two policies have been studied in the past for single product environments. Moreover, it was shown that it is beneficial to employ AIA and ATO simultaneously. In this article, we study the employment of such a composite assembly policy in a multiproduct environment with component commonality. When common components are used, ATO may also enable us to benefit from the risk pooling effect. We provide important managerial insights such as: the multiperiod problem is myopic and changes in inventory levels due to the use of common components, and demonstrate the potential profit increase compared to other policies.© 2007 Wiley Periodicals, Inc. Naval Research Logistics, 2007 [source]


Optimal material control in an assembly system with component commonality

NAVAL RESEARCH LOGISTICS: AN INTERNATIONAL JOURNAL, Issue 5 2001
Narendra Agrawal
Abstract Allocation of scarce common components to finished product orders is central to the performance of assembly systems. Analysis of these systems is complex, however, when the product master schedule is subject to uncertainty. In this paper, we analyze the cost,service performance of a component inventory system with correlated finished product demands, where component allocation is based on a fair shares method. Such issuing policies are used commonly in practice. We quantify the impact of component stocking policies on finished product delays due to component shortages and on product order completion rates. These results are used to determine optimal base stock levels for components, subject to constraints on finished product service (order completion rates). Our methodology can help managers of assembly systems to (1) understand the impact of their inventory management decisions on customer service, (2) achieve cost reductions by optimizing their inventory investments, and (3) evaluate supplier performance and negotiate contracts by quantifying the effect of delivery lead times on costs and customer service. © 2001 John Wiley & Sons, Inc. Naval Research Logistics 48:409,429, 2001 [source]


Alpha male chimpanzee grooming patterns: implications for dominance "style"

AMERICAN JOURNAL OF PRIMATOLOGY, Issue 2 2009
M.W. Foster
Abstract In social primates, individuals use various tactics to compete for dominance rank. Grooming, displays and contact aggression are common components of a male chimpanzee's dominance repertoire. The optimal combination of these behaviors is likely to differ among males with individuals exhibiting a dominance "style" that reflects their tendency to use cooperative and/or agonistic dominance tactics. Here, we examine the grooming behavior of three alpha male chimpanzees at Gombe National Park, Tanzania. We found that (1) these males differed significantly in their tendency to groom with other males; (2) each male's grooming patterns remained consistent before, during and after his tenure as alpha, and (3) the three males tended to groom with high- middle- and low-ranking partners equally. We suggest that body mass may be one possible determinant of differences in grooming behavior. The largest male exhibited the lowest overall grooming rates, whereas the smallest male spent the most time grooming others. This is probably because large males are more effective at physically intimidating subordinates. To achieve alpha status, a small male may need to compensate for reduced size by investing more time and energy in grooming, thereby ensuring coalitionary support from others. Rates of contact aggression and charging displays conformed to this prediction, suggesting that each male exhibited a different dominance "style." Am. J. Primatol. 71:136,144, 2009. © 2008 Wiley-Liss, Inc. [source]


How to Set Minimum Acceptable Bids, with an Application to Real Estate Auctions

THE JOURNAL OF INDUSTRIAL ECONOMICS, Issue 4 2002
R. Preston McAfee
In a general auction model with affiliated signals, common components to valuations and endogenous entry, we compute the equilibrium bidding strategies and outcomes, and derive a lower bound on the optimal reserve price. This lower bound can be computed using data on past auctions combined with information about the subsequent sales prices of unsold goods. We illustrate how to compute the lower bound using data from real estate auctions. [source]


Compatibility of detergents with the microbatch-under-oil crystallization method

ACTA CRYSTALLOGRAPHICA SECTION D, Issue 6 2003
Patrick J. Loll
Detergents are required to solubilize integral membrane proteins and are common components of the solutions used to crystallize these molecules. It has been unclear whether these detergents are completely compatible with the oils used in the microbatch-under-oil crystallization technique, because they might conceivably be lost from solution by partitioning into the oil phase. The partitioning of the detergents n -octyl-,- d -glucopyranoside and Fos-Choline-12 into two different oils used for microbatch crystallization experiments has been examined. It was found that vigorous mixing and prolonged incubation of the aqueous detergent solutions with the oils leads to small losses of detergent (approximately 5% of the total detergent mass); however, gentle mixing that is more typical of the mixing encountered in a crystallization experiments leads to negligible loss of detergent. [source]


Determination of community structure through deconvolution of PLFA-FAME signature of mixed population

BIOTECHNOLOGY & BIOENGINEERING, Issue 3 2007
Dipesh K. Dey
Abstract Phospholipid fatty acids (PLFAs) as biomarkers are well established in the literature. A general method based on least square approximation (LSA) was developed for the estimation of community structure from the PLFA signature of a mixed population where biomarker PLFA signatures of the component species were known. Fatty acid methyl ester (FAME) standards were used as species analogs and mixture of the standards as representative of the mixed population. The PLFA/FAME signatures were analyzed by gas chromatographic separation, followed by detection in flame ionization detector (GC-FID). The PLFAs in the signature were quantified as relative weight percent of the total PLFA. The PLFA signatures were analyzed by the models to predict community structure of the mixture. The LSA model results were compared with the existing "functional group" approach. Both successfully predicted community structure of mixed population containing completely unrelated species with uncommon PLFAs. For slightest intersection in PLFA signatures of component species, the LSA model produced better results. This was mainly due to inability of the "functional group" approach to distinguish the relative amounts of the common PLFA coming from more than one species. The performance of the LSA model was influenced by errors in the chromatographic analyses. Suppression (or enhancement) of a component's PLFA signature in chromatographic analysis of the mixture, led to underestimation (or overestimation) of the component's proportion in the mixture by the model. In mixtures of closely related species with common PLFAs, the errors in the common components were adjusted across the species by the model. Biotechnol. Bioeng. 2007;96: 409,420. © 2006 Wiley Periodicals, Inc. [source]