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Columbia University (columbia + university)
Terms modified by Columbia University Selected AbstractsDrosophila melanogaster: the model organismENTOMOLOGIA EXPERIMENTALIS ET APPLICATA, Issue 2 2006David B. Roberts Abstract In the 20th century, there were two decades during which Drosophila melanogaster was the most significant model organism and each decade led to the establishment of new scientific disciplines. The first decade was roughly from 1910 and during this period a small group at Columbia University, headed by Thomas Hunt Morgan, established the rules of transmission genetics with which we are all familiar. In the second decade, roughly from 1970, many of the principles and techniques of the earlier period were used to determine the genetic control of basic aspects of the biology of organisms, notably their development and their behaviour. In this review I will show that it was not only the genius of the research workers (five were awarded Nobel Prizes and it has been argued, with justification, that at least one more should have been awarded) but also the special features of D. melanogaster that led to these advances. While Drosophila is still a significant model organism, the advent of molecular biology permits the investigation of organisms less amenable to genetic analysis, but the principles applied in these investigations were in the main principles laid down during the earlier work on Drosophila. [source] Interview with a Quality Leader,Karen Davis, Executive Director of The Commonwealth FundJOURNAL FOR HEALTHCARE QUALITY, Issue 2 2009Lecia A. Albright Dr. Davis is a nationally recognized economist, with a distinguished career in public policy and research. Before joining the Fund, she served as chairman of the Department of Health Policy and Management at The Johns Hopkins School of Public Health, where she also held an appointment as professor of economics. She served as deputy assistant secretary for health policy in the Department of Health and Human Services from 1977 to 1980, and was the first woman to head a U.S. Public Health Service agency. Before her government career, Ms. Davis was a senior fellow at the Brookings Institution in Washington, DC; a visiting lecturer at Harvard University; and an assistant professor of economics at Rice University. A native of Oklahoma, she received her PhD in economics from Rice University, which recognized her achievements with a Distinguished Alumna Award in 1991. Ms. Davis is the recipient of the 2000 Baxter-Allegiance Foundation Prize for Health Services Research. In the spring of 2001, Ms. Davis received an honorary doctorate in human letters from John Hopkins University. In 2006, she was selected for the Academy Health Distinguished Investigator Award for significant and lasting contributions to the field of health services research in addition to the Picker Award for Excellence in the Advancement of Patient Centered Care. Ms. Davis has published a number of significant books, monographs, and articles on health and social policy issues, including the landmark books HealthCare Cost Containment, Medicare Policy, National Health Insurance: Benefits, Costs, and Consequences, and Health and the War on Poverty. She serves on the Board of Visitors of Columbia University, School of Nursing, and is on the Board of Directors of the Geisinger Health System. She was elected to the Institute of Medicine (IOM) in 1975; has served two terms on the IOM governing Council (1986,90 and 1997,2000); was a member of the IOM Committee on Redesigning Health Insurance Benefits, Payment and Performance Improvement Programs; and was awarded the Adam Yarmolinsky medal in 2007 for her contributions to the mission of the Institute of Medicine. She is a past president of the Academy Health (formerly AHSRHP) and an Academy Health distinguished fellow, a member of the Kaiser Commission on Medicaid and the Uninsured, and a former member of the Agency for Healthcare Quality and Research National Advisory Committee. She also serves on the Panel of Health Advisors for the Congressional Budget Office. [source] The Columbia Cooperative Aging Program: An Interdisciplinary and Interdepartmental Approach to Geriatric Education for Medical InternsJOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 3 2006Mathew S. Maurer MD Although there is a critical need to prepare physicians to care for the growing population of older adults, many academic medical centers lack the geriatric-trained faculty and dedicated resources needed to support comprehensive residency training programs in geriatrics. Because of this challenge at Columbia University, the Columbia Cooperative Aging Program was developed to foster geriatric training for medical interns. For approximately 60 interns each year completing their month-long geriatric rotations, an integral part of this training now involves conducting comprehensive assessments with "well" older people, supervised by an interdisciplinary team of preceptors from various disciplines, including cardiology, internal medicine, occupational therapy, geriatric nursing, psychiatry, education, public health, social work, and medical anthropology. Interns explore individual behaviors and social supports that promote health in older people; older people's strengths, vulnerabilities, and risk for functional decline; and strategies for maintaining quality of life and independence. In addition, a structured "narrative medicine" writing assignment is used to promote the interns' reflections on the assessment process, the data gathered, and their clinical reasoning throughout. Preliminary measures of the program's effect have shown significant improvements in attitudes toward, and knowledge of, older adults as patients, as well as in interns' self-assessed clinical skills. For academic medical centers, where certified geriatric providers are scarce, this approach may be an effective model for fostering residency geriatric education among interns. [source] The Bunshaft Tapes: A Preliminary ReportJOURNAL OF ARCHITECTURAL EDUCATION, Issue 2 2000Reinhold Martin Among the material collected in the Gordon Bunshaft Papers in the Avery Architectural and Fine Arts Library Archives at Columbia University are seventeen audiocassette tapes documenting a series of interviews between Arthur Drexler (1925-1987), curator of architecture and design at the Museum of Modern Art, and Gordon Bunshaft (1909-1990) of Skidmore, Owings & Merrill (SOM). In these tapes, Bunshaft and Drexler proceed systematically through Bunshaft's work for SOM, with Drexler consistently probing for evidence of authorial intentionality, resisted by Bunshaft. This report considers the manner in which these tapes construct a complex "orality," in which Bunshaft's testimony refuses the intertextual mediation implied by Drexler's questions, which themselves rely on the authority of an oral testimony to guarantee the authenticity of the answers. In turn, Bunshaft's refusals to engage with architectural discourse in the name of a pseudotransparent pragmatics demonstrate the extent of his identification with the ethos of his clients, corporate executives whose "visionary" status in the postwar period was a function of their own-discursive-privileging of pragmatic action over reflective discourse. [source] Effect of Donor Age on Long-Term Survival Following Cardiac TransplantationJOURNAL OF CARDIAC SURGERY, Issue 2 2006Veli K. Topkara M.D. Our objective was to analyze the effect of donor age on outcomes after cardiac transplantation. Methods: We retrospectively studied 864 patients who underwent cardiac transplantation at New York Presbyterian Hospital , Columbia University between 1992 and 2002. Patients were divided into two groups; donor age <40 years (Group A, n = 600) and donor age ,40 years (Group B, n = 264). Results: Characteristics including gender, body mass index, and cytomegalovirus (CMV) status were significantly different between the two donor age groups. Race, CMV status, toxoplasmosis status, left ventricular assist device prior to transplant, diabetes mellitus, and retransplantation were similar in both the recipient groups, while age, gender, and BMI were different. Early mortality was lower in Group A, 5%, versus 9.5% in Group B. Multivariate analysis revealed recipient female gender (odd ratio (OR) = 1.71), retransplantation (OR = 1.63), and increased donor age (OR = 1.02) as significant predictors of poor survival in the recipient population. Actuarial survival at 1 year (86.7% vs 81%), 5 years (75% vs 65%), and 10 years (56% vs 42%) was significantly different as well with a log rank p = 0.002. Conclusions: These findings suggest that increased donor age is an independent predictor of long-term survival. However, the shortage of organs makes it difficult to follow strict guidelines when placing hearts; therefore, decisions need to be made on a relative basis. [source] View planning and automated data acquisition for three-dimensional modeling of complex sitesJOURNAL OF FIELD ROBOTICS (FORMERLY JOURNAL OF ROBOTIC SYSTEMS), Issue 11-12 2009Paul S. Blaer Constructing highly detailed three-dimensional (3-D) models of large complex sites using range scanners can be a time-consuming manual process. One of the main drawbacks is determining where to place the scanner to obtain complete coverage of a site. We have developed a system for automatic view planning called VuePlan. When combined with our mobile robot, AVENUE, we have a system that is capable of modeling large-scale environments with minimal human intervention throughout both the planning and acquisition phases. The system proceeds in two distinct stages. In the initial phase, the system is given a two-dimensional site footprint with which it plans a minimal set of sufficient and properly constrained covering views. We then use a 3-D laser scanner to take scans at each of these views. When this planning system is combined with our mobile robot it automatically computes and executes a tour of these viewing locations and acquires them with the robot's onboard laser scanner. These initial scans serve as an approximate 3-D model of the site. The planning software then enters a second phase in which it updates this model by using a voxel-based occupancy procedure to plan the next best view (NBV). This NBV is acquired, and further NBVs are sequentially computed and acquired until an accurate and complete 3-D model is obtained. A simulator tool that we developed has allowed us to test our entire view planning algorithm on simulated sites. We have also successfully used our two-phase system to construct precise 3-D models of real-world sites located in New York City: Uris Hall on the campus of Columbia University and Fort Jay on Governors Island. © 2009 Wiley Periodicals, Inc. [source] The Search for Mechanisms of Behavior Change in Evidence-Based Behavioral Treatments for Alcohol Use Disorders: OverviewALCOHOLISM, Issue 2007Robert B. Huebner Background:, Over the past three decades, the main question of interest to alcohol treatment researchers has concerned the main effects of a particular behavioral intervention or what works. Increasingly, alcohol treatment researchers are turning their attention to the underlying psychological, social, and even neurophysiologic processes or "active ingredients" that are driving therapeutic change. Method:, The articles contained in this supplement to Alcoholism: Clinical and Experimental Research grew out of invited presentations given at a one-day satellite session immediately preceding the 28th Annual Meeting of the Research Society on Alcoholism (RSA). The conference was a collaborative effort of the Center on Alcoholism, Substance Abuse, and Addiction at the University of New Mexico, the Center on Addiction and Substance Abuse at Columbia University, Brown University, and the National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health. Results:, The conference featured a mix of full-length presentations on conceptual and methodological issues, reports of original research findings, and lively discussion among speakers and conference participants. Understanding mechanisms of behavior change will benefit the field by identifying the key aspects of therapy that must be present for maximum effect, irrespective of the specific technique being applied; provide a new way to approach patient,treatment interactions; and lay the groundwork for understanding how change is affected by social and other extratreatment factors. Conclusions:, Although not a new topic to the field, understanding mechanisms of behavior change has begun to capture the interest of an increasing number of alcohol treatment researchers. Understanding behavior change is an exceedingly complex enterprise and innovative thinking and creative research designs will be required to advance the field. [source] Using School Staff to Establish a Preventive Network of Care to Improve Elementary School Students' Control of AsthmaJOURNAL OF SCHOOL HEALTH, Issue 6 2006Jean-Marie Bruzzese To address these problems, Columbia University and the New York City Department of Education and the New York City Department of Health and Mental Hygiene undertook a randomized controlled trial to test the efficacy of a comprehensive school-based asthma program. In this intervention, school nurses were trained to facilitate the establishment of a preventive network of care for children with asthma by coordinating communications and fostering relationships between families, PCPs, and school personnel. PCPs also received training regarding asthma management. There was limited support for this model. While case detection helped nurses identify additional students with asthma and nurses increased the amount of time spent on asthma-related tasks, PCPs did not change their medical management of asthma. Few improvements in health outcomes were achieved. Relative to controls, 12-months posttest intervention students had a reduction in activity limitations due to asthma (,35% vs ,9%, p < .05) and days with symptoms (26% vs 39%, p = .06). The intervention had no impact on the use of urgent health care services, school attendance, or caregiver's quality of life. There were also no improvements at 24-months postintervention. We faced many challenges related to case detection, training, and implementing preventive care activities, which may have hindered our success. We present these challenges, describe how we coped with them, and discuss the lessons we learned. (J Sch Health. 2006;76(6):307-312) [source] Women in Iran: An Online DiscussionMIDDLE EAST POLICY, Issue 4 2001Nikki R. Keddie This debate on the role of women in the Islamic Republic of Iran was conducted early in 2001 as part of the Gulf/2000 project at Columbia University, directed by Gary Sick. Normally these online discussions are reserved for members, but this topic is of such general interest and aroused such intense emotions that two of the participants were asked to edit the discussion for a wider audience. The final version was edited by Nikki R. Keddie, professor emerita of history at the University of California, Los Angeles, based on the selection and organization of the texts by co-editor Azita Karimkhany, alumna of Columbia University and researcher in Middle Eastern studies. For additional information on Gulf/2000, see the project website athttp:gulf2000.columbia.edu. [source] An Interview with Diego GambettaOXONOMICS, Issue 2 2009Article first published online: 18 DEC 200 Diego Gambetta is Professor of Sociology and official fellow at Nuffield College, University of Oxford. Born in Turin, Italy, he received his PhD in Social and Political Sciences from the University of Cambridge, U.K. in 1983. Since 1992 he has been in Oxford in various positions. He has been visiting professor at the University of Chicago, Columbia University, Science Po and the College de France in Paris. His main scholarly interests are trust, signalling theory and its applications, organised crime, and violent extremists. In 2000 he was made a Fellow of the British Academy. He is the author of numerous books including The Sicilian Mafia (Gambetta, 1993), Making Sense of Suicide Missions (Gambetta, 2005) and, most recently, The Codes of the Underworld (Gambetta, 2009). [source] Postcolonial Scholarship,Productions and Directions: An Interview With Gayatri Chakravorty SpivakCOMMUNICATION THEORY, Issue 3 2002Radha S. Hegde This interview took place on December 18, 2000, in Gayatri Chakravorty Spivak's office at Columbia University, New York. In a room lined with books and papers stacked high, Spivak spoke about postcolonial scholarship and its global challenges. Spanning a diverse range of interests, Gayatri Spivak's work has influenced critical scholarship across multiple disciplines throughout the world. Her scholarship has significantly shaped the course of postcolonial thinking and has had profound impact on conceptualizing issues of culture, identity, communication, and transnationalism. When asked about her interest in the areas of global communication flows, new technologies, and the politics of culture, Spivak referred us to two of her recent essays where she writes about global cities and cyberliteracy in the journal Gray Room and in Judith Butler's edited volume What's Left of Theory. In this interview, we asked Spivak to speak to issues concerning the intersections between communication and postcoloniality. [source] | ||||||||||||||||