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Clear Rationale (clear + rationale)
Selected AbstractsTowards a More Rational IMF Quota Structure: Suggestions for the Creation of a New International Financial ArchitectureDEVELOPMENT AND CHANGE, Issue 3 2000Raghbendra Jha The authors of this article argue that, in the absence of a well-founded quota formula, the very basis of the creation of the IMF as an institution at the centre of international financial arrangements was flawed; that there is no clear rationale for the determinants of quota structures and their weighting scheme; and that the quota allocation as an instrument seeks to target too many objectives. As a result, large and arbitrary cross-country variations exist in the relative impact of different determinants on the quota shares of different countries. The quota formulas therefore need to be reviewed and an alternative approach evolved, in which emphasis is placed on the size of the economy rather than its openness, along with efficiency parameters. The authors suggest some principles which might underpin redefined quota structures in support of a new financial architecture. They provide illustrative calculations using India as a case study, and trace the impact of the redefined quota structures against the backdrop of the impact of the Eleventh General Review on India's quota position. [source] Educating Australian pharmacists about the use of online information in community pharmacy practiceINTERNATIONAL JOURNAL OF PHARMACY PRACTICE, Issue 2 2005Margaret Bearman Lecturer Objectives Community pharmacists practice in an information technology-rich society, however many have not been educated in internet use for professional practice. The aims of this study were to investigate how community pharmacists use the internet in their practice; to develop an intervention to address their educational needs; and to examine the benefits and weakness of a flexible delivery programme. Method We conducted two focus groups investigating community pharmacists' internet use and education needs. We subsequently developed and provided a four-module educational course on CD ROM, ,Advanced web skills for pharmacists: finding quality on the internet'. In total, 147 pharmacists participated. A survey was conducted to evaluate the impact of the course. Key findings The focus group findings provided a clear rationale for an educational intervention. One-hundred and four pharmacists completed the course. Participating pharmacists were highly positive about the learning experience, in particular the provision of education by flexible delivery. Many reported specific changes to practice. They also described the time-consuming nature of the course as the biggest barrier to further education. Conclusions This project demonstrates the need for community pharmacists to have access to internet education. Flexible CD ROM-based learning provided a successful delivery medium. [source] The economics of soil productivity: local, national and global perspectivesLAND DEGRADATION AND DEVELOPMENT, Issue 6 2004D. J. Knowler Abstract Soil degradation is a mounting problem on many smallholder lands in developing countries. Economic analysis has been an important tool in addressing this problem, beginning with assessments of the financial attractiveness of investing in soil conservation works. Data compiled from 67 studies of the financial attractiveness of conservation technologies suggest that many can provide positive net returns at the farm level (64·2,per,cent). While such studies have made a valuable contribution, economists have been exploring additional applications of economics to the problem, such as the development of new perspectives under the guise of ecological economics. As a result, this paper argues it is an opportune time to assess progress in the field of economic analysis of soil degradation and to consider the policy ramifications of this research. Key issues are grouped into farm-level considerations, national policy linkages and global issues. A number of policy implications emerge. Clearly, devising effective incentives at the farm or community (collective action) level must be a priority. As part of this effort, even more attention should be paid to the influence of macroeconomic and sectoral policies on soil productivity. Since soil degradation is also a problem with global ramifications, there is a clear rationale for intervention at the international level via mechanisms such as international transfers. Copyright © 2004 John Wiley & Sons, Ltd. [source] Parkinson's disease and resistive exercise: Rationale, review, and recommendationsMOVEMENT DISORDERS, Issue 1 2008Michael J. Falvo MS Abstract Individuals with Parkinson's disease (PD) are not only burdened with disease-specific symptoms (i.e., bradykinesia, rigidity, and tremor), but are also confronted with age-associated progressive loss of physical function, perhaps to a greater extent than neurologically normal adults. Suggestions for the inclusion of resistive exercise into treatment to attenuate these symptoms were made over 10 years ago, yet very few well controlled investigations are available. The objective of this review is to establish a clear rationale for the efficacy of resistance training in individuals with PD. Specifically, we highlight musculoskeletal weakness and its relationship to function as well as potential training-induced adaptive alterations in the neuromuscular system. We also review the few resistance training interventions currently available, but limit this review to those investigations that provide a quantitative exercise prescription. Finally, we recommend future lines of inquiry warranting further attention and call to question the rationale behind current exercise prescriptions. The absence of reports contraindicating resistive exercise, the potential for positive adaptation, and the noted benefits of resistance training in other populations may provide support for its inclusion into a treatment approach to PD. © 2007 Movement Disorder Society [source] Enhancing endocrine response with novel targeted therapies,CANCER, Issue S3 2008Why have the clinical trials to date failed to deliver on the preclinical promise? Abstract Acquired resistance to endocrine therapies has severely limited their long-term effectiveness in breast cancer. In recent years a clear rationale has developed for combining signal transduction inhibitors (STIs) with endocrine therapies to delay the emergence of acquired resistance and enhance endocrine responsiveness. A variety of biologic agents have been developed to target key proteins along the EGFR, HER2, MAPK, and P13K/Akt signal transduction cascades. While several of these agents have shown early promise in selected breast cancer models, translating these data into convincing clinical results has been generally disappointing to date. By applying more rigorous trial design and tumor selection criteria to future trials, it is much more likely that adding the new generation of targeted therapies can fulfill its promise in enhancing endocrine responsiveness and our ability to treat breast cancer patients. Cancer 2008. © 2007 American Cancer Society. [source] | ||||||||||