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Characterization Study (characterization + study)
Selected AbstractsA Characterization Study of a Nanowire-Network Transistor with Various Channel LayersADVANCED MATERIALS, Issue 41 2009Jae Eun Jang The performance of a ZnO network transistor is studied by means of the change in threshold slope with varying number of nanowire channel layers. The threshold slope broadens as the number of layers in the channel increases and, in the case of a two-layer channel, a double turn-on effect can be observed. The gate-field simulation shows gate-field distortion by the surface of the nanowire. [source] Source selectivity: An assessment of volcanic glass sources in the southern primorye region, far East RussiaGEOARCHAEOLOGY: AN INTERNATIONAL JOURNAL, Issue 2 2008Trudy Doelman Artifacts made from volcanic glass have been found in archaeological contexts dating from the Late Palaeolithic (ca. 20,000 yr B.P.) through to the end of the Bronze Age (ca. 2700 yr B.P.) in the southern Primorye region of Far East Russia. A geoarchaeological survey of volcanic glass outcrops assessed the various potential sources to determine their potential for sustained exploitation. A characterization study of source samples and artifacts from 27 spatially and temporally dispersed sites using a combination of PIXE-PIGME and relative density identified which sources had actually been exploited and a technological analysis of the assemblages described patterns of use. The combination of these three approaches shows the impact of a relatively stable geological environment on patterns of procurement and exchange. © 2008 Wiley Periodicals, Inc. [source] MAPPING AND CLASSIFYING FLOW UNITS IN THE UPPER PART OF THE MID-CRETACEOUS SARVAK FORMATION (WESTERN DEZFUL EMBAYMENT, SW IRAN) BASED ON A DETEMINATION OF RESERVOIR ROCK TYPESJOURNAL OF PETROLEUM GEOLOGY, Issue 4 2007B. Beiranvand The mid-Cretaceous Sarvak Formation, the second-most important reservoir unit in Iran, is composed mainly of grain-supported carbonates. For the purposes of this study, flow units in the upper part of the formation were identified, mapped and classified as part of an integrated reservoir characterization study at a giant oilfield in SW Iran. Pore types and geometries, pore-scale diagenetic history and core-scale depositional attributes were logged using conventional petrographic and lithological methods. The resulting data were combined with core descriptions, mercury-injection capillary pressure data, and wireline log and geophysical data to identify five reservoir rock types: (i) highly oil-stained, grain-supported carbonates, including patch reef and barrier complex deposits with high porosities and permeabilities; (ii) leeward and seaward shoal deposits including grain-supported packstones and skeletal wackestones with high porosities and permeabilities; (iii) dominantly mud-supported lagoonal and open-marine facies with fair porosity and permeability; (iv) grain-supported but highly cemented facies which had poor reservoir characteristics; and (v) calcareous shales and shaly limestones with no reservoir quality. Based on the reservoir rock types, eight flow units were recognised. Subsequently, four reservoir zones were defined based on these flow units at a field scale. This study has contributed to our understanding of flow units in this complex carbonate reservoir, and has improved our ability to characterize and model the architecture of the reservoir from pore to core to field scale. [source] Growth and characterization study of multidimensional hierarchical ZnO nanostructuresPHYSICA STATUS SOLIDI (B) BASIC SOLID STATE PHYSICS, Issue 5 2007Dong Jun Park Abstract ZnO multidimensional hierarchical structure was successfully fabricated with the sequence of ZnO top layers/ZnO nanorods/ZnO buffer/Si(111) substrate by continuous controlling growth condition in metal organic chemical vapor deposition (MOCVD) system. Transmission electron microscopy (TEM) showed that ZnO nanorods in hierarchical structure had a single crystal hexagonal wurtzite structure with ,0001,ZnO growth direction. Only near band edge (NBE) emissions with very weak deep level emission are observed around 3.28 eV. This indicates that ZnO hierarchical structure grown by MOCVD shows a good optical quality and less interior defects. (© 2007 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim) [source] Disease Stage Characterization of Hepatorenal Fibrocystic Pathology in the PCK Rat Model of ARPKDTHE ANATOMICAL RECORD : ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY, Issue 8 2010Stephen B. Mason Abstract The rat Pck gene is orthologous to the human PKHD1 gene responsible for autosomal recessive polycystic kidney disease (ARPKD). Both renal and hepatic fibrocystic pathology occur in ARPKD. Affected humans have a variable rate of progression, from morbidly affected infants to those surviving into adulthood. This study evaluated the PCK rat, a model of slowly progressive ARPKD. This model originated in Japan and was rederived to be offered commercially by Charles River Laboratories (Wilmington, MA). Previous studies have described the basic aspects of PCK pathology from privately held colonies. This study provides a comprehensive characterization of rats from those commercially available. Rats were bred, maintained on a 12:12 hr light/dark cycle, fed (7002 Teklad), and water provided ad libitum. Male and female rats were evaluated from 4 through 35 weeks of age with histology and serum chemistry. As the hepatorenal fibrocystic disease progressed beyond 18 weeks, the renal pathology (kidney weight, total cyst volume) and renal dysfunction (BUN and serum creatinine) tended to be more severe in males, whereas liver pathology (liver weight as % of body weight and hepatic fibrocystic volume) tended to be more severe in females. Hyperlipidemia was evident in both genders after 18 weeks. Bile secretion was increased in PCK rats compared with age-matched Sprague Dawley rats. The PCK is an increasingly used orthologous rodent model of human ARPKD. This characterization study of hepatorenal fibrocystic pathology in PCK rats should help researchers select stages of pathology to study and/or monitor disease progression during their longitudinal studies. Anat Rec 293:1279,1288, 2010. © 2010 Wiley-Liss, Inc. [source] PROVENANCE STUDIES OF CHALCOLITHIC OBSIDIAN ARTEFACTS FROM NEAR LAKE URMIA, NORTHWESTERN IRAN USING WDXRF ANALYSISARCHAEOMETRY, Issue 1 2010K. A. NIKNAMI In 2005,2006 we initiated a major archaeological survey and chemical characterization study to investigate the long-term use of obsidian along the eastern shores of Lake Urmia, northwestern Iran. Previous research in the area suggested that almost all archaeological obsidian found in this area originated from the Nemrut Da, source located in the Lake Van region of Anatolia (Turkey). More recent research on obsidian artefacts from the Lake Urmia region has identified a significant number of obsidian artefacts with compositions different from the sources near Lake Van. This suggests that the obsidian artefacts are from a yet to be identified geological source, but possibly one that was not too distant. In order to advance our knowledge of Iranian obsidians and eventually refine provenance criteria we analysed obsidian from 22 Chalcolithic sites and some source areas. The compositions of both obsidian source samples and artefacts were determined using wave length dispersive X-ray fluorescence spectrometry (WDXRF). This paper presents results from the trace elemental analysis of both geological and archaeological obsidians, providing important new data concerning the diachronic relationship between lithic technology and raw material in the north-west of Iran. [source] A Systematic Approach for Scale-Down Model Development and Characterization of Commercial Cell Culture ProcessesBIOTECHNOLOGY PROGRESS, Issue 3 2006Feng Li The objective of process characterization is to demonstrate robustness of manufacturing processes by understanding the relationship between key operating parameters and final performance. Technical information from the characterization study is important for subsequent process validation, and this has become a regulatory expectation in recent years. Since performing the study at the manufacturing scale is not practically feasible, development of scale-down models that represent the performance of the commercial process is essential to achieve reliable process characterization. In this study, we describe a systematic approach to develop a bioreactor scale-down model and to characterize a cell culture process for recombinant protein production in CHO cells. First, a scale-down model using 2-L bioreactors was developed on the basis of the 2000-L commercial scale process. Profiles of cell growth, productivity, product quality, culture environments (pH, DO, pCO2), and level of metabolites (glucose, glutamine, lactate, ammonia) were compared between the two scales to qualify the scale-down model. The key operating parameters were then characterized in single-parameter ranging studies and an interaction study using this scale-down model. Appropriate operation ranges and acceptance criteria for certain key parameters were determined to ensure the success of process validation and the process performance consistency. The process worst-case condition was also identified through the interaction study. [source] | |||||||||||||