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Changing Patterns (changing + pattern)

Distribution by Scientific Domains

Medical Sciences	38%
Life Sciences	15%
Humanities and Social Sciences	13%
Business, Economics, Finance and Accounting	11%
Earth and Environmental Science	6%
Psychology	3%
Education	3%
Chemistry	3%
2 Other Domains	8%

Distribution within Medical Sciences

Neurology	15%
Dermatology	13%
Consumer Health General	7%
12 Other Subdomains	52%

Selected Abstracts

CHANGING PATTERN OF CORPORATE GOVERNANCE AND FINANCING IN THE KOREAN CHAEBOLS

ECONOMIC PAPERS: A JOURNAL OF APPLIED ECONOMICS AND POLICY, Issue 3 2007
BYUNG S. MIN
The de jure financial system in Korea has moved from mainly R (relationship)-mode financial contracts towards M (market)-mode contracts since the 1997 financial crisis, due largely to reforms introducing Anglo-American style corporate governance and the disintermediation of the larger business groups in corporate financing. Analysis shows that the effectiveness of this change in improving firms' performances has yet to be demonstrated. Unlike the disintermediation of the big-name firms, the affiliates of small and medium business groups and small and medium-sized independent firms have relied heavily on bank loans and internal finance. The impact of a more concentrated banking system and intensified competition on the type of corporate investment has yet to be analysed. [source]

Changing Patterns of Industrial Relations in Taiwan

INDUSTRIAL RELATIONS, Issue 3 2003
Shyh-Jer Chen
This article examines changing patterns of industrial relations (IR) in Taiwan. Although trade unions have become more autonomous since the lifting of martial law in the mid-1980s, trends such as the privatization of state-owned enterprises, industrial restructuring, flexible employment practices, and importation of foreign workers hinder union development. The millennium may represent a turning point for workers and their organizations because the Democratic Progressive Party (DPP) replaced the Kuomintang (KMT) as the ruling party. This may further union independence and power because the DPP tends to be a more pro-labor party. However, balancing the interests of workers and employers will still be a challenge for the DPP, particularly given employer opposition to many of the DPP's labor policies. [source]

Changing Patterns in Family Farming: The Case of the Pampa Region, Argentina

JOURNAL OF AGRARIAN CHANGE, Issue 3 2009
CARLA GRAS
In the past few decades, Argentine agriculture has been significantly reorganized. Changes include the marked growth of export production, the need for an increasing level of capital investment and technological incorporation into farms and the restructuring of public intervention. This paper examines the dynamics of farm exit and the adjustments made by capitalized family farmers in the Pampa region. We suggest transformations in family farms are the result of a substantial shift in their main characteristics which historically combined the use of family labour, a certain accumulation capacity and ownership status. In particular, we will discuss the different and changing patterns of farm operations and the adjustments made with respect to work and land tenure. [source]

Changing Patterns in Medication Use with Increasing Probability of Death for Older Medicare Beneficiaries

JOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 8 2010
Thomas Shaffer MHS
OBJECTIVES: To determine whether use of symptom relief drugs (e.g., antidepressants, anxiolytics, opioid analgesics, sleep aids) rises and use of two commonly prescribed classes of chronic medications (statins and osteoporosis drugs) falls with greater probability of death for older Medicare beneficiaries. DESIGN: Pooled cross-sectional study. SETTING: Noninstitutionalized older Medicare population in 2000 to 2005. PARTICIPANTS: Community-dwelling Medicare beneficiaries aged 65 and older (N=20,233). MEASUREMENTS: Use of medications measured according to dichotomous flags; intensity of use by annual medication fills. Annual probability of death modeled using logistic regression and stratified into seven groups with predicted probabilities of death that range from less than 5% to greater than 50%. Prevalence of use and intensity (mean prescription fills per month) were computed for each class of medication. RESULTS: For symptom relief medications, there is relatively constant use with increasing probability of death, along with greater intensity of use. For the two chronic medications, there was a monotonic decrease in use but at a relatively constant intensity. Decline in statin use ranged from 34.4% in the lowest mortality stratum to 17.6% for those in the highest (P<.001). Use of osteoporosis drugs fell from 10.4% to 6.6% over the same range (P<.001). CONCLUSION: Greater intensity of use of symptom relief medications with increasing probability of death is consistent with hypothesized use. The different profile for chronic medications suggests that the time to benefit is being considered regarding therapy initiation, which results in lower use. [source]

Changing Patterns of Drug and Alcohol Use in Fatally Injured Drivers in Washington State

JOURNAL OF FORENSIC SCIENCES, Issue 5 2006
Eugene W. Schwilke B.S.
ABSTRACT: We have previously reported on patterns of drug and alcohol use in fatally injured drivers in Washington State. Here we revisit that population to examine how drug use patterns have changed in the intervening 9 years. Blood and serum specimens from drivers who died within 4 h of a traffic accident between February 1, 2001, and January 31, 2002, were analyzed for illicit and therapeutic drugs and alcohol. Drugs when present were quantitated. Samples suitable for testing were obtained from 370 fatally injured drivers. Alcohol was detected above 0.01 g/100 mL in 41% of cases. The mean alcohol concentration for those cases was 0.17 g/100 mL (range 0.02,0.39 g/100 mL). Central nervous system (CNS) active drugs were detected in 144 (39%) cases. CNS depressants including carisoprodol, diazepam, hydrocodone, diphenhydramine, amitriptyline, and others were detected in 52 cases (14.1%), cannabinoids were detected in 47 cases (12.7%), CNS stimulants (cocaine and amphetamines) were detected in 36 cases (9.7%), and narcotic analgesics (excluding morphine which is often administered iatrogenically in trauma cases) were detected in 12 cases (3.2%). For those cases which tested positive for alcohol c. 40% had other drugs present which have the potential to cause or contribute to the driver's impairment. Our report also considers the blood drug concentrations in the context of their interpretability with respect to driving impairment. The data reveal that over the past decade, while alcohol use has declined, some drug use, notably methamphetamine, has increased significantly (from 1.89% to 4.86% of fatally injured drivers) between 1992 and 2002. Combined drug and alcohol use is a very significant pattern in this population and is probably overlooked in DUI enforcement programs. [source]

Changing pattern of care of boys with haemophilia in western European centres

HAEMOPHILIA, Issue 2 2005
H. Chambost
Summary., Haemophilia management is not uniform among countries, even within western Europe, that have close economic, social and cultural relationship. The European Paediatric Network PedNet aims to share experiences in the field of the care of boys with haemophilia. In 1998, a PedNet survey has shown significant disparities in 20 centres from 16 countries, particularly as regards the implementation of prophylaxis regimen. This survey has been updated in 2003 to describe the current status of haemophilia management in 22 centres and the changing pattern of care of boys with severe haemophilia in western Europe. Regular, continuous long-term prophylaxis is provided in all PedNet centres, more than 50% and 80,100% of boys being treated this way in 20/22 and 15/22 centres respectively. Twenty of the 22 centres (91%) recommend continuous prophylaxis (primary or secondary A) for a new patient. The use of recombinant factor VIII concentrates was already widespread in 1998 and a further expansion of recombinant products has been observed over the last 5 years. Recombinant FVIII is now used exclusively in nine centres and for more than 80% of boys with haemophilia A in nine other centres. The use of recombinant and plasma derived FIX is more balanced: among 18 centres where boys with haemophilia B are treated, 14 use recombinant FIX, and nine administer it to a majority of patients. Other modifications of practice have been stressed in this survey, such as more targeted use of central venous devices in the youngest boys and more extensive characterisation of genetic mutations. [source]

Changing pattern of imported cutaneous leishmaniasis in the Netherlands

CLINICAL & EXPERIMENTAL DERMATOLOGY, Issue 1 2005
J. E. Zeegelaar
Summary Cutaneous leishmaniasis (CL) in western countries seems to be appearing more frequently. Our aim was to determine if there has been a shift in countries where CL is acquired and whether the incidence has changed, and to assess current diagnostic procedures and treatment modalities. In a retrospective study medical records of patients with the diagnosis of CL at the Departments of Tropical Dermatology and Tropical Medicine, Academic Medical Center, Amsterdam, the Netherlands, from 1990 to 2000 were analysed. CL was diagnosed in 78 patients. The majority was acquired in Belize, Surinam, French Guyana and Bolivia. Giemsa stains were positive for the parasite in impression smears from 43% and in biopsies from 71%. Seventy-eight per cent of cases were culture-positive and 89% were PCR-positive. Sixty-two patients were treated systemically: pentavalent antimony (32), pentamidine isetionate (11), itraconazole (19), and 13 locally, the majority with a combination of cryosurgery and intralesional pentavalent antimony. Imported CL is becoming more frequent, with South and Middle American countries being important sources of infection. Multiple tests, of which PCR is the most sensitive, are required to confirm the diagnosis. Systemic treatment was given to the majority of the patients. [source]

Changing patterns of visual impairment

DEVELOPMENTAL MEDICINE & CHILD NEUROLOGY, Issue 4 2001
James E Jan
No abstract is available for this article. [source]

Changing patterns of ganglion cell coupling and connexin expression during chick retinal development

DEVELOPMENTAL NEUROBIOLOGY, Issue 4 2002
David L. Becker
Abstract We have used dye injection and immunolabeling to investigate the relationship between connexin (Cx) expression and dye coupling between ganglion cells (GCs) and other cells of the embryonic chick retina between embryonic days 5 and 14 (E5,14). At E5, GCs were usually coupled, via soma-somatic or dendro-somatic contacts, to only one or two other cells. Coupling increased with time until E11 when GCs were often coupled to more than a dozen other cells with somata in the ganglion cell layer (GCL) or inner nuclear layer (INL). These coupled clusters occupied large areas of the retina and coupling was via dendro-dendritic contacts. By E14, after the onset of synaptogenesis and at a time of marked cell death, dye coupling was markedly decreased with GCs coupled to three or four partners. At this time, coupling was usually to cells of the same morphology, whereas earlier coupling was heterogeneous. Between E5 and E11, GCs were sometimes coupled to cells of neuroepithelial morphology that spanned the thickness of the retina. The expression of Cx 26, 32, and 43 differed and their distribution changed during the period studied, showing correlation with events such as proliferation, migration, and synaptogenesis. These results suggest specific roles for gap junctions and Cx's during retinal development. © 2002 Wiley Periodicals, Inc. J Neurobiol 52: 280,293, 2002 [source]

Changing patterns of global wealth

ECONOMIC OUTLOOK, Issue 4 2008
Article first published online: 27 OCT 200
First page of article [source]

Changing patterns of human resource management in contemporary China: WTO accession and enterprise responses

INDUSTRIAL RELATIONS JOURNAL, Issue 4 2004
Ying Zhu
ABSTRACT This study examines the increasingly complex challenges facing human resource management (HRM) in China following the country's accession to the WTO and, consequently, the implications for further reform of government policy and enterprise-level HRM practices. The article concludes that current HR practices among enterprises vary depending on ownership, industrial sector, location and history. The direction of future changes may depend on the level of involvement from external forces as well as internal strategies adopted by Chinese enterprises to survive. [source]

Changing patterns of coeliac serology requests

ALIMENTARY PHARMACOLOGY & THERAPEUTICS, Issue 10 2009
K. E. EVANS
Summary Background, Accurate serological tests have revolutionized the diagnosis of coeliac disease. Aim, To quantify the volume of coeliac serology requests at a district hospital over a decade, identify their origin, assess positivity rates and subsequent duodenal biopsy and histological confirmation rates. Methods, Details of patients in whom coeliac serology was requested from 1997 to 2006 were obtained from laboratory databases. The origins of request were categorized into gastroenterology, general practice, paediatrics and other specialities. Duplicate requests were excluded. Results, A total of 9976 serological tests were requested. Testing increased from 302 in 1997, to 1826 in 2006. In all, 66% of requests were in females. Tests in children accounted for 14,25% of each year's total. General practitioner requests increased from 3.3% in 1997 to 52% in 2006. The proportion of positive serological results fell from 5.7% in 1997 to 2.6% in 2006. Duodenal biopsies were performed in approximately 85% of seropositive patients in earlier years and approximately 75% of seropositive patients in later years. Most nonbiopsied seropositive patients had serology requested by general practitioners. Biopsies confirmed coeliac disease in 91% of seropositive patients. Conclusion, Increasingly, coeliac serological testing is requested by general practitioners. Twice as many females are tested. Increasing test numbers but diminishing positivity rates suggest testing is requested at lower symptom thresholds. Positive serological results are often not confirmed histologically. [source]

Changing patterns of diet, physical activity and obesity among urban, rural and slum populations in north India

OBESITY REVIEWS, Issue 5 2008
K. Yadav
Summary Rapid urbanization and accompanying lifestyle changes in India lead to transition in non-communicable disease risk factors. A survey was done in urban, urban slum and rural population of Haryana, India, in a sample of 4129 men and 3852 women using WHO STEPS questionnaire. A very high proportion of all the three populations reported inadequate intake of fruits and vegetables. Rural men reported five times physical activity as compared with urban and urban slum men and rural women reported seven times physical activity as compared with women in the other two settings. Mean body mass index (BMI) was highest among urban men (22.8 kg m,2) followed by urban slum (21.0 kg m,2) and rural men (20.6 kg m,2) (P -value < 0.01). Similar trend was seen for women but at a higher level than men. Prevalence of obesity (BMI , 30 kg m,2) was highest for urban population (male = 5.5%, female = 12.6%) followed by urban slum (male = 1.9%, female = 7.2%) and rural populations (male = 1.6%, female = 3.8%). Urbanization increases the prevalence of the studied non-communicable disease risk factors, with women showing a greater increase as compared with men. Non-communicable disease control strategy needs to address urbanization and warrants gender sensitive strategies specifically targeting women. [source]

Changing patterns of inequality in birthweight and its determinants: a population-based study, Scotland 1980,2000

PAEDIATRIC & PERINATAL EPIDEMIOLOGY, Issue 5 2005
Lesley Fairley
Summary Birthweight is used as an indicator of individual and population health and is known to be strongly correlated with adult cardiovascular disease. This paper uses routinely collected maternity discharge data from Scotland between 1980 and 2000 to look at birthweight trends and the changes in the distribution of maternal risk factors for birthweight. We also examine the contributions of each of the risk factors to birthweight trends and investigate whether there has been a reduction in inequality in birthweight over time. Data from 1 282 172 singleton live births were used in the analysis. Both mean birthweight and low birthweight (LBW: <,2500 g) were used as outcomes. The risk factors studied were maternal age, parity, maternal height, marital status and occupational social class of the father. The slope and relative indices of inequality were used to measure the change in inequalities over time. Mean birthweight increased from 3320 g in 1980 to 3410 g in 2000, while the percentage LBW decreased slightly from 5.7% in 1980 to 5.4% in 2000. The prevalence of many risk factors changed; there has been an increase in the proportion of older mothers, single mothers, taller mothers and mothers with undetermined social class. Although most risk factors had a significant change in effect over time, the inequalities in birthweight between groups did not appear to diminish over time. Both the slope and relative index of inequality had a quadratic relationship over time, with the inequalities in birthweight being greatest in the early 1980s and late 1990s. [source]

Changing patterns in interventional bronchoscopy

RESPIROLOGY, Issue 4 2009
Nikolaos ZIAS
ABSTRACT Background and objective: Many interventional tools for airway disorders can now be delivered via flexible bronchoscopy (FB), including neodymium-yttrium aluminium garnet laser, electrocautery, argon plasma coagulation, cryotherapy, balloon dilatation and metal or hybrid stents. Comparison of outcomes for patients undergoing rigid bronchoscopy (RB) with those treated using FB highlights the usefulness of the FB approach. Methods: A retrospective medical record review of all interventional bronchoscopy procedures performed at Lahey Clinic over the past 8 years was conducted. Patients were categorized into two groups according to the procedure used, that is, RB (251 patients), and FB (161 patients) groups. Patients with malignancies were included as a separate subgroup, comprising 178 RB and 117 FB patients. For every procedure, the location of the lesion, patient survival from the first interventional procedure performed, and in patients with malignancy, additional treatments received such as chemotherapy and radiation were recorded. Results: Ninety per cent of RB procedures were performed in patients with tracheal or main stem lesions, while over half the patients undergoing FB had more distal lesions. A trend towards increasing use of FB for interventional procedures in recent years was noted. Conclusions: FB is a valuable alternative to RB for treating less advanced malignant disease or distal airway lesions. [source]

Changing patterns of antiepileptic drug use in pregnant Australian women

ACTA NEUROLOGICA SCANDINAVICA, Issue 2 2010
F. J. E. Vajda
Vajda FJE, Hollingworth S, Graham J, Hitchcock AA, O'Brien TJ, Lander CM, Eadie MJ. Changing patterns of antiepileptic drug use in pregnant Australian women. Acta Neurol Scand: 2010: 121: 89,93. © 2009 The Authors Journal compilation © 2009 Blackwell Munksgaard. Objective,,, To trace the pattern of antiepileptic drug (AED) use in pregnant Australian women annually from 1999 to 2007, and correlate it with the pattern of AED use in the wider community. Methods,,, Analysis of data from the Australian Register of AEDs in Pregnancy, related to Australian population data for AED prescriptions. Results,,, Over the study period, prescribing of carbamazepine, phenytoin and valproate for pregnant women decreased, and prescribing of lamotrigine, topiramate and levetiracetam increased. These changes tended to parallel prescribing trends in the wider community, except for valproate, whose prescribing in the overall community increased as its prescribing, and its dosage prescribed, decreased in pregnancy. Concomitant with this, there was a trend towards fewer births of foetuses with abnormalities. Conclusions,,, While otherwise following national AED prescribing trends, Australian prescribers are reducing the use and dose of valproate in pregnant women, likely in recognition of the teratogenic hazards of this drug. [source]

Changing patterns in the management of gastric volvulus over 14 years

BRITISH JOURNAL OF SURGERY (NOW INCLUDES EUROPEAN JOURNAL OF SURGERY), Issue 3 2000
W. J. Teague
Background: Gastric volvulus is an uncommon condition, which can be difficult to diagnose and treat. This study represents a large series of patients with the condition. Methods: All patients presenting with gastric volvulus over a 14-year period were reviewed. Results: Some 36 patients (median age 75 years) were identified. Volvulus, usually secondary to a hiatus hernia, presented acutely in 29 patients. The major symptoms were abdominal pain, vomiting and upper gastrointestinal haemorrhage. The most useful investigations were barium contrast studies and upper gastrointestinal endoscopy, which were helpful in 21 of 25 and 11 of 18 patients respectively. Treatment was conservative in five patients, by open surgery in 13 and laparoscopic repair in 18 (three converted to open operation). There were no major complications and no deaths. Median hospital stay was shorter in patients treated by laparoscopic rather than open surgery (6 (range 4,36) versus 14 (7,50) days; P < 0·05). Conclusion: Acute and chronic gastric volvulus can be treated successfully by either open or laparoscopic surgery. However, laparoscopic surgery now represents a safe and acceptable approach, with minimal morbidity and a significantly shorter hospital stay. This is likely to be of considerable benefit for the treatment of a predominantly elderly population, often with significant co-morbidity. © 2000 British Journal of Surgery Society Ltd [source]

Changing patterns of zoophilic fungal infections in the West of Scotland illustrated by two cases of tinea corporis from domestic rodents

CLINICAL & EXPERIMENTAL DERMATOLOGY, Issue 8 2009
F. Al-Niaimi
No abstract is available for this article. [source]

Neuropathology of Rett syndrome

DEVELOPMENTAL DISABILITIES RESEARCH REVIEW, Issue 2 2002
Dawna Duncan Armstrong
Abstract Rett Syndrome is unlike any other pediatric neurologic disease, and its clinical-pathologic correlation can not be defined with standard histology techniques. Based on hypotheses suggested by careful clinical observations, the nervous system of the Rett child has been explored utilizing morphometry, golgi preparations, computerized tomography, magnetic resonance imaging, chemistry, immunocytochemistry, autoradiography, and molecular biologic techniques. From these many perspectives we conclude that Rett syndrome is not a typical degenerative disorder, storage disorder, nor the result of gross malformation, infectious or neoplastic processes. There remain regions of the brain that have not been studied in detail but the available data suggest that the neuropathology of Rett syndrome can be summarized as follows: the Rett brain is small for the age and the height of the patient; it does not become progressively smaller over three to four decades; it has small dendritic trees in pyramidal neurons of layers III and V in selected lobes (frontal, motor, and temporal); it has small neurons with an increased neuronal packing density; it has an immature expression of microtubular protein-2 and cyclooxygenase; it exhibits a changing pattern of neurotransmitter receptors with an apparent reduction in many neurotransmitters, possibly contributing to some symptomatology. A mutation in Mecp2 causes this unique disorder of brain development. Neuronal mosaicism for normal and mutated Mecp2 produces a consistent phenotype in the classic female patient and a small brain with some preserved islands of function, but with an inability to support hand use and speech. This paper summarizes our current observations about neuropathology of Rett syndrome. MRDD Research Reviews 2002;8:72,76. © 2002 Wiley-Liss, Inc. [source]

Close range digital photogrammetric analysis of experimental drainage basin evolution

EARTH SURFACE PROCESSES AND LANDFORMS, Issue 3 2003
J. Brasington
Abstract Despite the difficulties of establishing formal hydraulic and geometric similarity, small-scale models of drainage basins have often been used to investigate the evolution and dynamics of larger-scale landforms. Historically, this analysis has been restricted to planform basin characteristics and only in the last decade has the topographic similarity of experimental landscapes been explored through explicitly three-dimensional parameters such as the distributions of cumulative drainage area, area,slope and catchment elevation. The current emphasis on three-dimensional morphometry reflects a growing awareness of the descriptive paucity of planform data and the need for more robust analysis of spatial scaling relationships. This paradigm shift has been significantly facilitated by technological developments in topographic survey and digital elevation modelling (DEM) which now present the opportunity to acquire and analyse high-resolution, distributed elevation data. Few studies have, however, attempted to use topographic modelling to provide information on the changing pattern and rate of sediment transport though an evolving landscape directly by using multitemporal DEM differencing techniques. This paper reports a laboratory study in which digital photogrammetry was employed to derive high-resolution DEMs of a simulated landscape in declining equilibrium at 15 minute frequency through a 240 minute simulation. Detailed evaluation of the DEMs revealed a vertical precision of 1·2 mm and threshold level of change detection between surfaces of ±3 mm at the 95 per cent confidence level. This quality assurance set the limits for determining the volumetric change between surfaces, which was used to recover the sediment budget through the experiment and to examine local - and basin-scale rates of sediment transport. A comparison of directly observed and morphometric estimates of sediment yield at the basin outlet was used to quantify the closure of the sediment budget over the simulation, and revealed an encouragingly small 6·2 per cent error. The application of this dynamic morphological approach has the potential to offer new insights into the controls on landform development, as demonstrated here by an analysis of the changing pattern of the basin sediment delivery ratio during network growth. Copyright © 2003 John Wiley & Sons, Ltd. [source]

Changing pattern of care of boys with haemophilia in western European centres

An exploration of the contribution of the community nurse to rehabilitation

HEALTH & SOCIAL CARE IN THE COMMUNITY, Issue 4 2003
Rosie Kneafsey RGN BSc
Abstract Effective hospital and community rehabilitation services are increasingly recognised as a means of meeting the changing pattern of health and social care need. While the district or community nurse has the potential to play a central part in community rehabilitation provision, this role has received relatively scant attention in the literature. This paper describes research findings on community nurses' perceptions of their role and potential contribution to rehabilitation. As part of a wider, 2-year, qualitative investigation of the role of the nurse in rehabilitation, fieldwork was undertaken with both district and community staff nurses. This comprised focus group discussions and interviews with staff recruited as a consequence of the follow-up of patients' experiencing rehabilitation. The findings indicate that community-based nurses contributed to patient rehabilitation by making assessments, referring on to other members of the multi-professional team, advocating for and liaising with other services, helping people to adapt, teaching and motivating patients and carers, supporting and involving families, and providing technical care. A number of challenges to community-based nursing roles were apparent, including feelings of exclusion, lack of recognition, a lack of time for rehabilitation and paucity of referrals for rehabilitation. Greater clarity and recognition is needed of the community-based nursing contribution to rehabilitation, and there is a need to ensure that community nursing assessments contribute to patients' rehabilitation goals and the promotion of independent living. [source]

Cocirculation of and coinfections with hepatitis A virus subgenotypes IIIA and IB in patients from Pune, western India

HEPATOLOGY RESEARCH, Issue 2 2007
Shobha Chitambar
Aim:, During the 1990s, a changing pattern of epidemiology of hepatitis A was reported in different populations of India. The present study was undertaken to investigate the molecular epidemiology of hepatitis A virus (HAV) strains over a period of 10 years. Methods:, Stool/serum samples were collected from hepatitis A patients clinically presenting acute viral hepatitis and hepatic encephalopathy. Reverse transcriptase polymerase chain reaction (RT-PCR) was performed to detect HAV-RNA. HAV genomes were examined by sequencing PCR products of VP1/2A junction (168 bp) and RNA polymerase (116 bp) regions. Results:, Subgenotype IIIA and IB were detected in 74.2% and 9.7% of specimens, respectively, while 16.1% of patients had mixed infections. Sewage samples also showed presence of both IIIA (9/10) and IB (1/10) subgenotypes. RNA polymerase region showed two clusters constituting 51.6% and 19.4% strains closer to Nor21 and HM175 strains, respectively, in clinical specimens. Three isolates appeared as discordant subgenotypes in VP1/2A and RNA polymerase regions. Conclusion:, The data revealed cocirculation of and coinfection with subgenotypes IIIA and IB, with predominance of IIIA and genetic heterogeneity of HAV strains in western India. [source]

Higher Education Communities and Academic Identity

HIGHER EDUCATION QUARTERLY, Issue 3 2000
Maurice Kogan
The slippery use to which the word ,community' is applied in higher education studies and pronouncements makes it desirable that it should be better defined and related to more bounded assumptions about individual academic identity and relationships within academe. There is discussion of the academic communities of the invisible colleges and their modes of internal governance by elites and the communitarian implications of the changing pattern of institutional management. The relationship of academics and their institutions to the wider world of society and the economy is considered. It is concluded that external connections are not best pursued through assumptions of shared community but of acceptance of differentiation and exchange. [source]

Recording dental caries in archaeological human remains

INTERNATIONAL JOURNAL OF OSTEOARCHAEOLOGY, Issue 4 2001
Simon Hillson
Abstract Dental caries is an important condition to record in archaeological collections, but the way in which recording is carried out has a large effect on the way in which the results can be interpreted. In living populations, dental caries is a disease that shows a strong relationship with age. Both the nature of carious lesions and their frequency change with successive age groups from childhood to elderly adulthood. There is also a progression in the particular teeth in the dentition which are most commonly affected and, in general, the molars and premolars are involved much more frequently than the canines and incisors. Lower teeth are usually affected more than upper, although the condition usually involves the right and left sides fairly equally. In the high tooth wear rate populations represented by many archaeological and museum collections, there is a complex relationship between the form of lesions and the state of wear, which adds yet another range of factors to the changing pattern of caries with increasing age. In the same populations, chipping, fracture and anomalous abrasion of teeth are also common, and these contribute similarly to the distribution and forms of carious lesion observed. Amongst the living, the pattern of ante-mortem tooth loss is important in understanding caries and, in archaeological material, there is also the complicating factor of post-mortem tooth loss. Finally, there is the question of diagnosis. There are diagnostic problems even in epidemiological studies of living patients and, for archaeological specimens, diagenetic change and the variable preservation of different parts of the dentition add further complications. For all these reasons, it is difficult to define any one general index of dental caries to represent the complete dentition of each individual, which would be universally suitable for studying a full range of collections from archaeological sites or museums. Variation in the nature of collections, their preservation, tooth wear, and ante-mortem and post-mortem tooth loss mean that when such a general index appears to differ between sites, there could be many other reasons for this, in addition to any genuine differences in caries incidence and pattern that might have been present. It is suggested here that the best approach is instead to make comparisons separately for each tooth type, age group, sex, lesion type and potential lesion site on the tooth. Copyright © 2001 John Wiley & Sons, Ltd. [source]

CHARACTERISTICS OF CHAMBER TEMPERATURE CHANGE DURING VACUUM COOLING

JOURNAL OF FOOD PROCESS ENGINEERING, Issue 2 2009
RUI ZHAO
ABSTRACT In order to investigate the dynamic changing pattern of the chamber temperature with chamber pressure during vacuum cooling, 10 repeated experiments were conducted to evaluate the time-dependent temperature and pressure in the vacuum chamber during vacuum cooling of water. Water was chosen in the experiment as it is the main component of most foods. The results showed that the temperature in the vacuum chamber significantly depended on variation in pressure at different pumping stages. The temperature changes in the chamber generally followed a certain pattern. In the early stage of vacuum cooling, the chamber temperature dropped very quickly (0.26 K/s), while at the end of vacuum cooling, it increased rapidly (0.22 K/s), and was about 11.8 K higher than the ambient temperature when the vacuum was released with ambient air flowing back to the chamber. PRACTICAL APPLICATIONS Vacuum cooling is a rapid cooling method for the food industry; further understanding of the vacuum cooling mechanism can help to control and improve this cooling process. Temperature changing pattern and distribution affects the quality of the food product in vacuum cooling process. As the main component of most foods is water, it is necessary to investigate the dynamic temperature changing pattern and distribution with vacuum pressure during vacuum cooling of water so that the information obtained could be used as a reference for vacuum cooling of food products. [source]

Well,Being: Concepts and Measures

JOURNAL OF SOCIAL ISSUES, Issue 4 2002
Robert L. Kahn
Well,being, or quality of life, is a continuing goal for individuals and a major criterion for the evaluation of governments and societies. As a research concept, however, it has been marked by persisting problems of definition and measurement and by uncertainties about its changing pattern over the life course. In this article, these issues are discussed; the concept of well,being is "unpacked" and a model of stocks and flows is described as applicable to the analysis of well,being. Finally, the concept of resilience is proposed as important for research on well,being in relation to age. [source]

A longitudinal study of scholars attitudes and behaviors toward open-access journal publishing

JOURNAL OF THE AMERICAN SOCIETY FOR INFORMATION SCIENCE AND TECHNOLOGY, Issue 3 2010
Jingfeng Xia
This research applies statistical time series analysis to examine the changing pattern of scholars' attitudes toward open-access (OA) journal publishing from the early 1990s. By synthesizing survey results in existing studies, this research focuses on representative aspects of the attitudes and behaviors recorded through the years. It finds that although an increase in the publishing and awareness rates of scholars with regard to OA journals has been observed, scholars have been consistently concerned with the low prestige of such journals and their lack of peer review, which is not the case in practice. It is hoped that the findings will provide useful information for the improvement of OA advocacy. [source]

Variations of ferritin levels over a period of 15 years as a compliance chelation index in thalassemic patients

AMERICAN JOURNAL OF HEMATOLOGY, Issue 4 2001
Antonios Kattamis
Abstract We studied the changing pattern of the distribution of ferritin levels in 430 regularly-transfused patients with thalassemia in an attempt to evaluate compliance of chelation with deferoxamine. The study covered 15 years and was divided in three periods: 1981 , 1985, 1986 , 1990, and 1991 , 1995. The patients were stratified in age-groups. The mean ferritin levels of each period were calculated for each patient individually. The study showed that: (i) When all the patients were compared as a group, there was a significant decrease in mean ferritin between 1981 , 1985 and 1991 , 1995, despite a significant change in the patients' mean age; (ii) When patients of same age were compared between periods, there was a decrease in mean ferritin between 1981 , 1985 and 1991 , 1995, as well as a decrease in the proportion of patients with ferritin >4000 ,g/L, with a parallel increase in the proportion of patients who had ferritin <2000 ,g/L; (iii) When the same patients were followed longitudinally, they showed a decrease in their ferritin levels in all age groups with the exception of the late adolescence period. The decrease in iron overload observed in patients on close follow up implies that compliance with chelation therapy has improved with time and therefore, a favourable influence in survival could be expected. Am. J. Hematol. 68:221,224, 2001. © 2001 Wiley-Liss, Inc. [source]

Free IAA in stigmas and styles during pollen germination and pollen tube growth of Nicotiana tabacum

PHYSIOLOGIA PLANTARUM, Issue 1 2008
Dan Chen
Although many studies have emphasized the importance of auxin in plant growth and development, the thorough understanding of its effect on pollen,pistil interactions is largely unknown. In this study, we investigated the role of free IAA in pollen,pistil interactions during pollen germination and tube growth in Nicotiana tabacum L. through using histo and subcellular immunolocalization with auxin monoclonal antibodies, quantification by HPLC and ELISA together with GUS staining in DR5::GUS -transformed plants. The results showed that free IAA in unpollinated styles was higher in the apical part and basal part than in the middle part, and it was more abundant in the transmitting tissue (TT). At the stage of pollen germination, IAA reached its highest content in the stigma and was mainly distributed in TT. After the pollen tubes entered the styles, the signal increased in the part where pollen tubes would enter and then rapidly declined in the part where pollen tubes had penetrated. Subcellular localization confirmed the presence of IAA in TT cells of stigmas and styles. Accordingly, a schematic diagram summarizes the changing pattern of free IAA level during flowering, pollination and pollen tube growth. Furthermore, we presented evidence that low concentration of exogenous IAA could, to a certain extent, facilitate in vitro pollen tube growth. These results suggest that IAA may be directly or indirectly involved in the pollen,pistil interactions. Additionally, some improvements of the IAA immunolocalization technique were made. [source]