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Acyl Chlorides (acyl + chloride)
Selected AbstractsAn Efficient Bismuth(III) Chloride-Catalyzed Synthesis of 1,1-Diarylalkenes via Friedel,Crafts Reaction of Acyl Chloride or Vinyl Chloride with ArenesADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 14 2006Hongbin Sun Abstract In the presence of catalytic amount of bismuth(III) chloride, the reactions of acyl chlorides or vinyl chlorides with arenes afforded 1,1-diarylalkenes in 25,82,% isolated yield. In the case of the reaction of acyl chlorides with arenes, the procedure includes an initial Friedel,Crafts acylation, subsequent formation of vinyl chlorides and final Friedel,Crafts-type vinylation of another arene molecule with vinyl chloride. This paper reports the first Lewis acid-catalyzed cleavage of the CCl bond of vinyl chloride and its application in the synthesis of multiply subtituted alkenes. [source] Kinetic Resolution of Racemic Secondary Alcohols Mediated by N -Methylimidazole in the Presence of Optically Active Acyl ChloridesEUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 14 2010Loïc Leclercq Abstract N -Methylimidazole was used to promote the acylation of secondary racemic alcohols and to carry out their kinetic resolution through intermediate chiral acyl imidazolium chlorides. The kinetic resolution could be turned into a catalytic process in the presence of a catalytic amount of N -methylimidazole. [source] ChemInform Abstract: Using Pd-Salen Complex as an Efficient Catalyst for the Copper- and Solvent-Free Coupling of Acyl Chlorides with Terminal Alkynes under Aerobic Conditions.CHEMINFORM, Issue 39 2010Mohammad Bakherad No abstract is available for this article. [source] ChemInform Abstract: Synthesis of Polyfluoroaromatic Ketones from Polyfluoroarylzinc Compounds and Acyl Chlorides in the Presence of CuCl.CHEMINFORM, Issue 37 2010A. S. Vinogradov No abstract is available for this article. [source] ChemInform Abstract: Synthesis of Symmetrical Carboxylic Acid Anhydrides from Acyl Chlorides in the Presence of In Metal and DMF.CHEMINFORM, Issue 28 2009Joong-Gon Kim Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Intermolecular Coupling of Alkynes, Isocyanates, and Acyl Chlorides: An Efficient Method for the Synthesis of 5-Hydroxypyrrol-2(5H)-ones.CHEMINFORM, Issue 15 2008Ken-ichiro Kanno Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Formation of 3-Aryl-5-nitroisocoumarins from 5-Nitroisocoumarins and Aromatic Acyl Chlorides under Friedel,Crafts Conditions.CHEMINFORM, Issue 5 2008Peter T. Sunderland Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] The Surfactant-Promoted Cross-Coupling Reactions of Arylboronic Acids with Carboxylic Anhydrides or Acyl Chlorides in Water.CHEMINFORM, Issue 47 2007Bingwei Xin Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Synthesis of Ketones from Acyl Chlorides and Triorganoindium Reagents by Pd-Catalyzed Cross-Coupling.CHEMINFORM, Issue 11 2007C. Croix Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Palladium-Catalyzed Chemoselective Cross-Coupling of Acyl Chlorides and Organostannanes.CHEMINFORM, Issue 9 2006Rachel Lerebours Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] A Convenient Method for Preparing Aromatic ,,,-Unsaturated Ketones from ,,,-Unsaturated Acyl Chlorides and Arylboronic Acids via Suzuki,Miyaura Type Coupling Reaction.CHEMINFORM, Issue 21 2004Yoshio Urawa Abstract For Abstract see ChemInform Abstract in Full Text. [source] Indium-Mediated Formation of Propargyl Ketones from Aldehydes or Acyl Chlorides.CHEMINFORM, Issue 19 2003Jacques Auge Abstract For Abstract see ChemInform Abstract in Full Text. [source] A Novel Solid-Phase Chlorinating Reagent for the Synthesis of Acyl Chlorides.CHEMINFORM, Issue 13 2003Guanglin Luo Abstract For Abstract see ChemInform Abstract in Full Text. [source] ChemInform Abstract: Nucleophilic Trifluoromethylation of Acyl Chlorides Using the Trifluoromethyl Iodide/TDAE Reagent.CHEMINFORM, Issue 34 2002Naoto Takechi Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] An Atropo-Stereogenic Diphosphane Ligand with a Proximal Cationic Charge: Specific Catalytic Properties of a Palladium Complex ThereofEUROPEAN JOURNAL OF INORGANIC CHEMISTRY, Issue 19 2008Nathalie Debono Abstract A class of cationic diphosphane ligands combining phosphane and amidiniophosphane moieties is illustrated on the N -methyl,N -naphthylbenzimidazolium framework. The palladium(II) complex thereof is described and compared to the corresponding complex of the analogous neutral diphosphane. Contrary to first-level expectations, the N2C,P and N2CP,Pd bonds in the cationic diphosphane complex are not longer than those occurring in its neutral counterpart. In the cationic ligand, the proximal positive charge is indeed conjugated to one phosphanyl group, and the coordination scheme is tentatively interpreted by resonance of the phosphane,metal dative bond (+N2C,P:,[Pd]) with a carbene,phosphenium dative bond (N2C:,[+P:,Pd]). Despite this peculiar structural feature, the electronic , donation (vs. , acceptation) towards the palladium centre remains lowered in the cationic ligand. This specific property can be a priori valuable in a catalytic process where oxidative addition is not the limiting step. It is indeed shown that although the neutral complex is more active in Suzuki coupling reactions, the cationic complex is more active in Sonogashira-type coupling reactions involving predissociated halide substrates, namely an acyl chloride. These likely atropo-chiral ligands deserve to be resolved for application in asymmetric catalysis.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008) [source] Preparation of Diamidochloro(cyclopentadienyl)titanium Derivatives as Pre-Catalysts for Olefin Polymerization , X-ray Molecular Structure of [Ti(,5 -C5H5){1,2-C6H4(NCH2CH2CH3)2}Cl] and [Ti{,5 -C5H4(SiMe3)}{1,2-C6H4(NCH2CH2CH3)2}Cl]EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, Issue 15 2004Vanessa Tabernero Abstract The synthesis of N,N,-alkyl 1,2-phenylenediamines 1,2-C6H4(NHR)2 [R = CH2CH2CH3 (nPr), CH2tBu (Np)] was carried out in three steps by lithiation of the primary 1,2-phenylenediamine, reaction with the appropriate acyl chloride and reduction with LiAlH4. The addition of nBuLi to a stirred solution of N,N,-alkyl diamines in cold hexane resulted in the immediate deposition of the corresponding lithium salts, which react with [MCpR,Cl3] to give the diamidochloro(,5 -cyclopentadienyl)titanium and -zirconium complexes [MCpR,{1,2-C6H4(NR)2}Cl] (4,10) [M = Ti, Zr; CpR, = ,5 -C5H5, ,5 -C5(CH3)5, ,5 -C5H4(SiMe3); R = nPr, Np]. The compound [Ti(,5 -C5H5){1,2-C6H4(NnPr)2}Cl] (3) was obtained by treatment of [Ti(,5 -C5H5)Cl3] with 1,2-C6H4(NHnPr)2 in the presence of NEt3 in toluene. All the reported compounds were characterized by the usual analytical and NMR spectroscopic methods. The molecular structures of 3 and 7 were determined by single-crystal X-ray crystallography. The compounds described here were further investigated as potential olefin polymerization catalysts. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004) [source] Efficient synthesis of benzothieno[3,2- d]-1,2,4-triazolo [1,5- a]pyrimidin-5(1H)-ones via a tandem aza-Wittig/heterocumulene-mediated annulationJOURNAL OF HETEROCYCLIC CHEMISTRY, Issue 5 2009Sheng-Zhen Xu The carbodiimides 2, obtained from reactions of iminophosphorane 1 with isocyanates, reacted with hydrazine to give selectively 3-amino-2-arylaminobenzothieno[3,2- d]pyrimidin-4(3H)-ones 4. Reactions of 4 with triphenylphosphine, hexachloroethane, and Et3N produced iminophosphoranes 5. A tandem aza-Wittig reaction of iminophosphorane 5 with isocyanate, acyl chloride generated benzothieno[3,2- d]-1,2,4-triazolo[1,5- a]pyrimidin-5(1H)-ones 7 and 9 in satisfactory yields. The effects of the nucleophiles on cyclization have been investigated. J. Heterocyclic Chem., (2009). [source] Catalytic reactions of oxetanes with protonic reagents and aprotic reagents leading to novel polymersJOURNAL OF POLYMER SCIENCE (IN TWO SECTIONS), Issue 5 2007Hiroto Kudo Abstract This paper reports new addition reactions of oxetanes with certain protonic reagents such as carboxylic acid, phenol, and thiol, and with certain aprotic reagents such as acyl chloride, thioester, phosphonyl dichloride, silyl chloride, and chloroformate using quaternary onium salts as catalysts. The kinetic study of the addition reactions of oxetanes was also investigated. These new addition reactions were applicable to the synthesis of new polymers. These polyaddition systems could also construct both polymer main chains and reactive side chains. The alternating copolymerization of oxetanes with carboxylic anhydride was performed. Furthermore, it was found that anionic ring-opening polymerization of oxetanes containing hydroxy groups proceeded to afford the hyperbranched polymer (HBP) with an oxetanyl group and many hydroxy groups at the ends of the polymer chains. Alkali developable photofunctional HBPs were synthesized by the polyaddition of bis(oxetane)s or tris(oxetane)s, and their patterning properties were examined, too. The photo-induced cationic polymerization of the polymers with pendant oxetanyl groups and the thermal curing reactions of polyfunctional oxetanes (oxetane resins) were also examined to give the crosslinking materials quantitatively. © 2007 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 44: 709,726, 2007 [source] Preparation of oily core polyamide microcapsules via interfacial polycondensation,POLYMER INTERNATIONAL, Issue 4 2003L Soto-Portas Abstract Microcapsules obtained by interfacial polycondensation from an original system based on the polyaddition of specific di- or polyamines and more classical acyl chloride molecules were studied. The originality of the system lies in the fact that the encapsulated agent is the internal phase allowing its incorporation without an organic solvent, which is an advantage from the point of view of environmental protection. Once the optimal parameters of the emulsion were determined, the membrane formation was studied by optimizing the emulsification and reaction times in relation to simultaneous acyl chloride hydrolysis. The microcapsules were obtained by interfacial polycondensation between an excess of amine functions (diamine and diethylenetriamine) and acyl chloride (sebacoyl chloride and 1,3,5-benzene tricarbonyl trichloride) from an oil-in-water emulsion in the presence of 88% hydrolyzed poly(vinyl alcohol) as a surfactant. Various formulations in terms of COCl concentration, crosslinking agent concentration, excess of amine functions, emulsification and reaction times were prepared. The hydrolysis of acyl halide functions is the main parameter which influences the growth of the membrane. The increase in acyl chloride function concentration allows compensation for that lost by hydrolysis, and increases the encapsulation yield to about 90%. The degree of crosslinking of the membrane was controlled in order to minimize the subsequent release of oil by the addition of trifunctional monomers. An optimal formulation was developed offering high encapsulation yield and optimal elastic behaviour. Almost spherical capsules, with a membrane thickness of approximately 500,nm, relatively smooth internal walls and crumpled external walls, were observed by scanning electron microscopy. © 2003 Society of Chemical Industry [source] Regiospecific Three-Component Access to Fluorescent 2,4-Disubstituted Quinolines via One-Pot Coupling-Addition-Cyclocondensation-Sulfur Extrusion Sequence,EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 18 2010Sven Rotzoll Abstract 2,4-Di- and 2,4,7-trisubstituted quinolines are readily synthesized in a regioselective fashion from acyl chlorides, terminal alkynes, and 2-aminothiophenols by a consecutive, microwave-assisted one-pot three-component Sonogashira coupling-Michael addition,cyclocondensation sequence and following sulfur extrusion in moderate to good yields. The terminal sulfur extrusion step was studied by DFT computations. The absorption spectra of 2,4-disubstituted quinolines can be rationalized by DFT-ZINDO-CI calculations and all derivatives show intense blue emission upon UV excitation. [source] An Efficient Bismuth(III) Chloride-Catalyzed Synthesis of 1,1-Diarylalkenes via Friedel,Crafts Reaction of Acyl Chloride or Vinyl Chloride with ArenesADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 14 2006Hongbin Sun Abstract In the presence of catalytic amount of bismuth(III) chloride, the reactions of acyl chlorides or vinyl chlorides with arenes afforded 1,1-diarylalkenes in 25,82,% isolated yield. In the case of the reaction of acyl chlorides with arenes, the procedure includes an initial Friedel,Crafts acylation, subsequent formation of vinyl chlorides and final Friedel,Crafts-type vinylation of another arene molecule with vinyl chloride. This paper reports the first Lewis acid-catalyzed cleavage of the CCl bond of vinyl chloride and its application in the synthesis of multiply subtituted alkenes. [source] Synthesis and Biological Activity of Some 1,3-Dihydro-2H -3-benzazepin-2-ones with a Piperazine Moiety as Bradycardic AgentsARCHIV DER PHARMAZIE, Issue 2 2010Hong-Yu Liang Abstract A series of 1,3-dihydro-2H -3-benzazepin-2-ones with a piperazine moiety were designed and synthesized by treating the common intermediate of 1,3-dihydro-7,8-dimethoxy-3-[3-(1-piperazinyl)propyl]-2H -3-benzazepin-2-ones with a variety of N -aryl-2-chloroacetamides and acyl chlorides. Their structures have been characterized by 1H-NMR, MS, and elemental analysis. The title compounds were evaluated for their bradycardic activity in vitro. Most of the synthesized compounds exhibited some vasorelaxant activity and heart-rate-reducing activity with bradycardic potency. [source] | |||||||||||||