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Achievable Goal (achievable + goal)
Selected AbstractsAddressing Minority Issues in Renal Transplantation: Is More Equitable Access an Achievable Goal?AMERICAN JOURNAL OF TRANSPLANTATION, Issue 1 2002Robert S. Gaston No abstract is available for this article. [source] Evaluating social performance in the context of an ,audit culture': a pilot social review of a gold mine in Papua New GuineaCORPORATE SOCIAL RESPONSIBILITY AND ENVIRONMENTAL MANAGEMENT, Issue 2 2008Martha Macintyre Abstract The growth of sustainable development frameworks that emphasize the social dimension has created a need for new approaches to evaluate social performance. The paper describes the design and pilot of a social review conducted at the Lihir Gold Mine in Papua New Guinea. The aim was to investigate more integrated measures , understood as combining qualitative and quantitative measures, and bridging international and local community standards , of social performance. The paper discusses the demands of time and resources placed on a range of stakeholders as part of a review. It then identifies impediments to developing integrated approaches, and analyses these with reference to Power's (1999, 2003) discussion of an emerging audit culture, which focuses on management systems rather than first-order questions of quality and performance. The authors conclude that, while an audit culture influenced this pilot study, an integrated approach on these two dimensions remains an achievable goal. Copyright © 2007 John Wiley & Sons, Ltd and ERP Environment. [source] Determinants for the successful establishment of exotic ants in New ZealandDIVERSITY AND DISTRIBUTIONS, Issue 4 2005Philip J. Lester ABSTRACT Biological invasions can dramatically alter ecosystems. An ability to predict the establishment success for exotic species is important for biosecurity and conservation purposes. I examine the exotic New Zealand ant fauna for characteristics that predict or determine an exotic species' ability to establish. Quarantine records show interceptions of 66 ant species: 17 of which have established, 43 have failed to establish, whereas nests of another six are periodically observed but have failed to establish permanently (called ,ephemeral' establishment). Mean temperature at the highest latitude and interception variables were the only factors significantly different between established, failed or ephemeral groups. Aspects of life history, such as competitive behaviour and morphology, were not different between groups. However, in a stepwise discriminant analysis, small size was a key factor influencing establishment success. Interception rate and climate were also secondarily important. The resulting classification table predicted establishment success with 71% accuracy. Because not all exotic species are represented in quarantine records, a further discriminant model is described without interception data. Though with less accuracy (65%) than the full model, it still correctly predicted the success or failure of four species not used in the previous analysis. Techniques for improving the prediction accuracy are discussed. Predicting which species will establish in a new area appears an achievable goal, which will be a valuable tool for conservation biology. [source] Understanding and Modulating AgeingIUBMB LIFE, Issue 4-5 2005Suresh IS Rattan Abstract Ageing is characterized by a progressive accumulation of molecular damage in nucleic acids, proteins and lipids. The inefficiency and failure of maintenance, repair and turnover pathways is the main cause of age-related accumulation of damage. Research in molecular gerontology is aimed at understanding the genetic and epigenetic regulation of survival and maintenance mechanisms at the levels of transcription, post-transcriptional processing, post-translational modifications, and interactions among various gene products. Concurrently, several approaches are being tried and tested to modulate ageing in a wide variety of organisms. The ultimate aim of such studies is to improve the quality of human life in old age and prolong the health-span. Various gerontomodulatory approaches include gene therapy, hormonal supplementation, nutritional modulation and intervention by free radical scavengers and other molecules. A recent approach is that of applying hormesis in ageing research and therapy, which is based on the principle of stimulation of maintenance and repair pathways by repeated exposure to mild stress. A combination of molecular, physiological and psychological modulatory approaches can realize "healthy ageing" as an achievable goal in the not-so-distant future. IUBMB Life, 57: 297-304, 2005 [source] Hepatitis B vaccine: Risks and benefits of universal neonatal vaccinationJOURNAL OF PAEDIATRICS AND CHILD HEALTH, Issue 3 2001CR Macintyre Abstract: Global eradication of hepatitis B, which has infected over 2000 million people worldwide, is an achievable goal. Hepatitis B vaccine is effective and safe, and is recommended in Australia as a four-dose childhood schedule commencing with a neonatal dose. A neonatal dose has a greater impact on carriage, the main reservoir of transmission, due to the inverse relationship of age and risk of chronic carriage. Universal vaccination is clearly cost-effective in countries of high hepatitis B endemicity but less so in countries of low endemicity. Other factors affecting the perceived benefits of universal vaccination in low-risk countries include the use of the preservative thiomersal in hepatitis B vaccines, and case reports of multiple sclerosis (MS) and unexplained fever in recipients. Careful epidemiological studies have failed to confirm any risk of MS or fever with the hepatitis B vaccine, which is now thiomersal-free. Other arguments against universal vaccination include ,unnecessary' vaccination of low-risk neonates. However, selective vaccination programmes targeting at-risk neonates are often poorly implemented and do not protect against horizontal transmission in early childhood. Universal vaccination, which is safe and effective, is the only practical means of achieving global eradication of hepatitis B. [source] The Impact of Surgery in the Management of the Head and Neck Carcinoma Involving the Carotid Artery,THE LARYNGOSCOPE, Issue 10 2008Enver Ozer MD Abstract Objectives/Hypothesis: To demonstrate the feasibility of the carotid artery dissection and/or resection and reanastomosis, and to show its positive impact on survival and disease control rates for the head and neck carcinomas involving the carotid artery. Study Design: Tertiary center (Comprehensive Cancer Center). Case series review. Methods: The data of 90 patients with head and neck malignancies involving the carotid artery were operated for the carotid artery dissection and/or resection, and reanastomosis in the last 10 years were retrospectively reviewed and analyzed. Results: Eighty (89%) of the 90 patients' head and neck malignancies were squamous cell carcinoma. Fifty-two (65%) and 28 (35%) of 80 patients were recurrent and stage IV disease, respectively. There was no stage I to III disease. Carotid artery was dissected and preserved in 64 (71.1%) of the 90 patients. Eighteen (20%) of 90 patients needed carotid artery dissection with resection and reanastomosis. Eight (8.9%) patients were unresectable. Sixty (75%) of 80 patients needed reconstruction with regional or free flaps and grafts. Overall 2- and 5-year estimated survivals were 32.4% and 27.8% for all; 14.3% and 10.7% for recurrent; 64.3% and 57.8% for stage IV previously untreated; and 22.0% and 22.0% for carotid artery resected-reanastomosed patients, respectively. Conclusions: The carotid artery dissection without resection is an achievable goal in majority of patients with the advanced stage head and neck carcinoma involving the carotid artery. Resection and reanastomosis of carotid artery, especially in the previously untreated carotid involved patients, is a feasible surgery and achieves better survival and disease control rates when compared with the unresected or recurrent disease patients. [source] Darfur and the failure of the responsibility to protectINTERNATIONAL AFFAIRS, Issue 6 2007ALEX DE WAAL When official representatives of more than 170 countries adopted the principle of the ,responsibility to protect' (R2P) at the September 2005 World Summit, Darfur was quickly identified as the test case for this new doctrine. The general verdict is that the international community has failed the test due to lack of political will. This article argues that the failure is real but that it is more fundamentally located within the doctrine of R2P itself. Fulfilling the aspiration of R2P demands an international protection capability that does not exist now and cannot be realistically expected. The critical weakness in R2P is that the ,responsibility to react' has been framed as coercive protection, which attempts to be a middle way between classic peacekeeping and outright military intervention that can be undertaken without the consent of the host government. Thus far, theoretical and practical attempts to create this intermediate space for coercive protection have failed to resolve basic strategic and operational issues. In addition, the very act of raising the prospect of external military intervention for human protection purposes changes and distorts the political process and can in fact make a resolution more difficult. Following an introductory section that provides background to the war in Darfur and international engagement, this article examines the debates over the R2P that swirled around the Darfur crisis and operational concepts developed for the African Union Mission in Sudan (AMIS) and its hybrid successor, the UN,African Union Mission in Darfur (UNAMID), especially during the Abuja peace negotiations. Three operational concepts are examined: ceasefire, disarmament and civilian protection. Unfortunately, the international policy priority o bringing UN troops to Darfur had an adverse impact on the Darfur peace talks without grappling with the central question of what international forces would do to resolve the crisis. Advocacy for the R2P set an unrealistic ideal which became the enemy of achievable goals. [source] | ||||||||||||||||