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Accurate Localization (accurate + localization)
Selected AbstractsAccurate localization of supernumerary mediastinal parathyroid adenomas by a combination of structural and functional imagingJOURNAL OF MEDICAL IMAGING AND RADIATION ONCOLOGY, Issue 3 2004GC Mackie Summary Reoperation for refractory or recurrent hyperparathyroidism following parathyroidectomy carries the potential for increased morbidity and the possibility of failure to localize and remove the lesion intraoperatively. Reported herein are three cases demonstrating the combined use of sestamibi scintigraphy, CT and MR for accurate localization of mediastinal parathyroid adenomas. [source] Usefulness of diagnostic imaging in primary hyperparathyroidismINTERNATIONAL JOURNAL OF UROLOGY, Issue 1 2003KAZUYA SEKIYAMA Abstract Background : In patients with primary hyperparathyroidism, prevention of urinary stone recurrence can be achieved by surgical removal of the enlarged parathyroid gland. To ensure the efficacy of surgery for primary hyperparathyroidism, preoperative localization of the enlarged gland is important. In the present study, usefulness of diagnostic imaging for localization of the enlarged gland was investigated in primary hyperparathyroidism. Methods : We retrospectively examined the findings of imaging studies and clinical records in 79 patients (97 glands) who underwent surgical treatment for primary hyperparathyroidism at Chiba University Hospital between 1976 and 2000. The detection rates of accurate localization were investigated for imaging techniques, such as ultrasonography (US), computed tomography (CT), magnetic resonance imaging (MRI), thallium-201 and technetium-99m pertechnetate (Tl-Tc) subtraction scintigraphy and 99mTc-methoxyisobutylisonitrile (MIBI) scintigraphy, and analysed in relation to the size and weight of the gland and pathological diagnosis. Results : The detection rates by US, CT, MRI, Tl-Tc subtraction scintigraphy and MIBI scintigraphy were 70%, 67%, 73%, 38% and 78%, respectively. The overall detection rate changed from 50% to 88% before and after 1987. The detection rate of MIBI scintigraphy was superior to Tl-Tc subtraction scintigraphy. Conclusion : In primary hyperparathyroidism, improvement of accurate localization of an enlarged parathyroid gland was demonstrated along with recent advances in imaging techniques including MIBI scintigraphy. [source] Accurate localization of supernumerary mediastinal parathyroid adenomas by a combination of structural and functional imagingJOURNAL OF MEDICAL IMAGING AND RADIATION ONCOLOGY, Issue 3 2004GC Mackie Summary Reoperation for refractory or recurrent hyperparathyroidism following parathyroidectomy carries the potential for increased morbidity and the possibility of failure to localize and remove the lesion intraoperatively. Reported herein are three cases demonstrating the combined use of sestamibi scintigraphy, CT and MR for accurate localization of mediastinal parathyroid adenomas. [source] Improved spatial localization based on flow-moment-nulled and intra-voxel incoherent motion-weighted fMRINMR IN BIOMEDICINE, Issue 3 2003Allen W. Song Abstract Functional MRI signal based on the blood oxygenation level-dependent contrast can reveal brain vascular activities secondary to neuronal activation. It could, however, arise from vascular compartments of all sizes, and in particular, be largely influenced by contributions of large vein origins that are distant from the neuronal activities. Alternative contrasts can be generated based on the cerebral blood flow or volume changes that would provide complementary information to help achieve more accurate localization to the small vessel origins. Recent reports also indicated that apparent diffusion coefficient-based contrast using intravoxel incoherent motion (IVIM) weighting could be used to efficiently detect synchronized signal changes with the functional activities. It was found that this contrast has significant arterial contribution where flow changes are more dominant. In this study, a refined approach was proposed that incorporated the flow-moment-nulling (FMN) strategy to study signal changes from the brain activation. The results were then compared with those from conventional IVIM- and BOLD-weighted acquisitions. It was shown that the activated region using the new acquisition strategy had smaller spatial extent, which was contained within the activated areas from the other two methods. Based on the known characteristics of the conventional IVIM and BOLD contrasts, it was inferred that the FMN,IVIM acquisition had improved selective sensitivity towards smaller vessels where volume changes were prevalent. Therefore, such an acquisition method may provide more specific spatial localization closely coupled to the true neuronal activities. Copyright © 2003 John Wiley & Sons, Ltd. [source] | ||||||||||