Accumulated Experience (accumulated + experience)

Distribution by Scientific Domains


Selected Abstracts


Errors in technological systems

HUMAN FACTORS AND ERGONOMICS IN MANUFACTURING & SERVICE INDUSTRIES, Issue 4 2003
R.B. Duffey
Massive data and experience exist on the rates and causes of errors and accidents in modern industrial and technological society. We have examined the available human record, and have shown the existence of learning curves, and that there is an attainable and discernible minimum or asymptotic lower bound for error rates. The major common contributor is human error, including in the operation, design, manufacturing, procedures, training, maintenance, management, and safety methodologies adopted for technological systems. To analyze error and accident rates in many diverse industries and activities, we used a combined empirical and theoretical approach. We examine the national and international reported error, incident and fatal accident rates for multiple modern technologies, including shipping losses, industrial injuries, automobile fatalities, aircraft events and fatal crashes, chemical industry accidents, train derailments and accidents, medical errors, nuclear events, and mining accidents. We selected national and worldwide data sets for time spans of up to ,200 years, covering many millions of errors in diverse technologies. We developed and adopted a new approach using the accumulated experience; thus, we show that all the data follow universal learning curves. The vast amounts of data collected and analyzed exhibit trends consistent with the existence of a minimum error rate, and follow failure rate theory. There are potential and key practical impacts for the management of technological systems, the regulatory practices for complex technological processes, the assignment of liability and blame, the assessment of risk, and for the reporting and prediction of errors and accident rates. The results are of fundamental importance to society as we adopt, manage, and use modern technology. © 2003 Wiley Periodicals, Inc. Hum Factors Man 13: 279,291, 2003. [source]


Japan's strategic contributions to hydro-meteorological disaster mitigation in the world: planning to establish the UNESCO,PWRI Centre

HYDROLOGICAL PROCESSES, Issue 6 2006
Tetsuya Ikeda
Hydro-meteorological disasters such as floods are major challenges that need to be overcome in order to realize sustainable development and poverty alleviation for humankind. Devastating flood disasters have occurring in various locations throughout the world, and there has recently been rising concern that the intensity and frequency of catastrophic floods may be increasing. Being located on the eastern edge of monsoonal Asia and having climatic variations according to the seasonal and regional conditions, Japan has long suffered from numerous flood disasters, and thus has developed advanced flood management policies. This paper aims to discuss flood disasters in Japan and the recently improved flood management policies. In addition, this paper introduces a new plan attempted by the Public Works Research Institute (PWRI) of Japan that takes advantage of the wealth of long accumulated experience and knowledge in the hydro-meteorological field. The PWRI is now working toward the establishment of an International Centre on Water-related Hazard and Risk Management by acquiring UNESCO's auspices. In order to contribute to the global challenge of reducing devastating hydro-meteorological disasters all over the world, this centre aims to conduct research, capacity-building and training programmes, and information networking activities at the local, national, regional and global levels. The aim is to prevent and mitigate hydro-meteorological disasters from the viewpoint of sustainable and integrated river basin management. Copyright © 2006 John Wiley & Sons, Ltd. [source]


Formal pooling of health risks in sub-Saharan Africa: Reflections on the obstacles encountered

INTERNATIONAL SOCIAL SECURITY REVIEW, Issue 2 2002
Bruno Meessen
Over the past few years a number of institutional solutions to the pooling of health risks have been advanced in a great number of reform proposals for developing countries. The empirical arguments in favour of such recommendations have the full force of accumulated experience in countries that have long been industrialized. However, rural realities in Africa and Asia naturally have very little to do with past or present realities in western countries. Whereas the technical-cooperation and scientific community has relatively good knowledge of techniques, a number of recent experiences of the introduction of mutual benefit schemes in Africa seem to show that this approach is now enjoying some success. The low levels of membership in particular make it essential to tackle the problem fully. This article tries to identify the various possible explanations for this lack of enthusiasm in sub-Saharan Africa. [source]


Advances in adult living donor liver transplantation: A review based on reports from the 10th anniversary of the adult-to-adult living donor liver transplantation meeting in Tokyo

LIVER TRANSPLANTATION, Issue 6 2004
Yasuhiko Sugawara
In 1993, the Shinshu Group performed the first successful adult-to-adult living donor liver transplantation (LDLT). During the first 10 years of LDLT, many technical innovations have been reported. The major limitation of LDLT for adult recipients is the size of the graft. To overcome the problem, several graft types were designed, including left liver graft with caudate lobe, right liver, modified right liver, and right lateral sector and dual grafts. The necessity and criteria of reconstruction of middle hepatic vein is still on debate in right liver graft without trunk of middle hepatic vein. Biliary reconstruction remains a significant source of morbidity in LDLT. Donor safety must always be the primary consideration in LDLT and the selection criteria and management of the living donor must continue to be refined. On February 21, 2004, the 10th anniversary of the adult-to-adult LDLT meeting was held in Tokyo to review the accumulated experience and the presented information is summarized. (Liver Transpl 2004;10:715,720.) [source]


Teratogenicity of antiepileptic drugs: role of drug metabolism and pharmacogenomics

ACTA NEUROLOGICA SCANDINAVICA, Issue 1 2007
R. Sankar
The approach to clinical decision-making pertaining to the use of antiepileptic drugs (AEDs) during pregnancy has relied on previous accumulated experience and, since the 1990s, on data from pregnancy registries. The limitations of this process are that no information regarding the chemical attributes of the AED under consideration, nor the role of a number of enzyme systems that are known to interact with foreign compounds to modify their potential for harm, are included. The role of the hepatic mixed function oxidase system may be especially important in conferring teratogenic risk. However, systems such as epoxide hydrolase, glutathione reductase, superoxide dismutase and other toxin-scavenging systems may be important modifiers that lower the risk. Knowledge is also accumulating on the interactions of AEDs with molecular targets such as histone deacetylase and peroxisome proliferator-activated receptors that may play important roles in teratogenesis. While our knowledge of these factors are incomplete, progress can be achieved by beginning to include these concepts in our discussion on the topic and by promoting research that may improve our ability to individualize the analysis of risk for a specific patient with regards to specific AEDs. [source]