|
| ||
|
|
||
Acaricidal Activity (acaricidal + activity)
Selected AbstractsMilbemycin ,17 and Related Compounds Synthesized from Milbemycin A4: Synthetic Procedure and Acaricidal Activities.CHEMINFORM, Issue 13 2004Takahiro Tsukiyama Abstract For Abstract see ChemInform Abstract in Full Text. [source] Acaricidal activity against Panonychus citri of a ginkgolic acid from the external seed coat of Ginkgo bilobaPEST MANAGEMENT SCIENCE (FORMERLY: PESTICIDE SCIENCE), Issue 3 2006Weigao Pan Abstract An acaricidal substance extracted from the external seed coat of Ginkgo biloba L. was identified by UV (ultraviolet), IR (infrared), EI-MS (electron impact ion source mass spectrometry), 1H NMR (nuclear magnetic resonance) and 13C NMR as 6-[(Z)-10-heptadecenyl]-2-hydroxybenzoic acid (compound 1). Laboratory bioassay on citrus red mite, Panonychus citri (Mcg), showed that compound 1 possessed the following properties. (i) Powerful contact toxicity with an LC50 of 5.2 mg litre,1 after 24 h that was similar to that of pyridaben (LC50 = 3.4 mg litre,1) and significantly superior to that of omethoate (LC50 = 122 mg litre,1). Furthermore, its LC90 was 13.4 mg litre,1 after 24 h, which is significantly superior to both pyridaben (LC90 = 69.6 mg litre,1) and omethoate (LC90 = 453 mg litre,1). (ii) Quick-acting acaricidal activity. At identical concentrations, compound 1 was much faster-acting than pyridaben or omethoate. (iii) Compound 1 had strong corrosive action on the cuticle of P. citri but no phytotoxicity to plants. Copyright © 2006 Society of Chemical Industry [source] Acaricidal properties of piperazine and its derivatives against house-dust and stored-food mitesPEST MANAGEMENT SCIENCE (FORMERLY: PESTICIDE SCIENCE), Issue 6 2009Chi-Hoon Lee Abstract BACKGROUND: Piperazine derivatives possess pharmacological properties, yet the acaricidal activity of these compounds has not been investigated. This study was conducted to evaluate the colour alteration and acaricidal activity of piperazine derivatives against Dermatophagoides spp. and Tyrophagus putrescentiae (Schrank) using filter paper and fumigant methods. RESULTS: In a fumigant bioassay, 1-phenylpiperazine (7.83 µg cm,2) against D. farinae (Hughes) was found to be 4.7 times more toxic than DEET (36.84 µg cm,2), followed by benzyl benzoate (9.72 µg cm,2), piperazine (11.41 µg cm,2), 1-ethoxycarbonylpiperazine (20.14 µg cm,2) and 1-(2-methoxyphenyl)piperazine (22.14 µg cm,2). In a filter paper bioassay, 1-(2-methoxyphenyl)piperazine (3.65 µg cm,2) was 5.7 times more toxic than DEET (20.64 µg cm,2), followed by 1-ethoxycarbonylpiperazine (4.02 µg cm,2), 1-phenylpiperazine (4.75 µg cm,2), benzyl benzoate (7.83 µg cm,2) and piperazine (10.59 µg cm,2). Similar results have been exhibited with piperazine derivatives against D. pteronyssinus (Troussart). However, no activity against T. putrescentiae was observed for piperazine derivatives, except for piperazine. CONCLUSIONS: These results indicate that piperazine derivatives may be suitable as vapour-phase acaricide fumigants owing to their high volatility, acaricidal activity and safety. 1-Phenylpiperazine was found to be an excellent mite indicator based on the colour change it induced. Taken together, these findings indicate that piperazine derivatives may be used to replace existing problematical acaricides owing to their activity and ability to act as a mite indicator. Copyright © 2009 Society of Chemical Industry [source] The discovery of HNPC-A3066: a novel strobilurin acaricidePEST MANAGEMENT SCIENCE (FORMERLY: PESTICIDE SCIENCE), Issue 3 2009Aiping Liu Abstract BACKGROUND: Although more than ten strobilurin analogues have been commercialized since 1996 as fungicides, only one was available as an acaricide as of 2003. To search for novel strobilurin analogues with unique biological activities, a synthetic screening programme was carried out. RESULTS: Syntheses of compounds analogous to the commercialized fungicide metominostrobin and the acaricide fluacrypyrim led to the discovery of a lead compound, (E)-2-{2-[[3,5-bis(trifluoromethyl)phenoxy]methyl]phenyl}-2-(methoxyimino)- N -methylacetamide (3b), that showed moderate acaricidal activity against Tetranychus urticae Koch. Compound 3b has a 3,5-(CF3)2 -phenoxymethyl group instead of the unsubstituted phenoxy substituent in metominostrobin. Optimization of compound 3b was achieved by introducing an oxime ether bridge along with an alkylthio(alkyl) branch in place of the oxymethylene chain between two aromatic moieties, as well as by replacing the methoxyiminoacetamide group with a methoxyacrylate structure, leading to (E)- methyl 2-{2-[[[(Z)[1-(3,5-bis(trifluoromethyl)phenyl)-2-methylthioethylidene]amino]oxy] methyl]phenyl}-3-methoxyacrylate (6c) and (E)- methyl 2-{2-[[[(Z)[1-(3,5-bis(trifluoromethyl)phenyl)-1-methylthiomethylidene]amino]oxy]methyl]phenyl}-3-methoxyacrylate (9a, HNPC-A3066). CONCLUSION: The above two compounds (6c, 9a) were shown to exhibit potent acaricidal and fungicidal activity. Compound 9a (HNPC-A3066) also exhibits larvicidal and ovicidal activities against various acarids. The acaricidal potency is comparable with those of commercial acaricides such as fluacrypyrim, tebufenpyrad and chlorfenapyr. Copyright © 2008 Society of Chemical Industry [source] Acaricidal activity against Panonychus citri of a ginkgolic acid from the external seed coat of Ginkgo bilobaPEST MANAGEMENT SCIENCE (FORMERLY: PESTICIDE SCIENCE), Issue 3 2006Weigao Pan Abstract An acaricidal substance extracted from the external seed coat of Ginkgo biloba L. was identified by UV (ultraviolet), IR (infrared), EI-MS (electron impact ion source mass spectrometry), 1H NMR (nuclear magnetic resonance) and 13C NMR as 6-[(Z)-10-heptadecenyl]-2-hydroxybenzoic acid (compound 1). Laboratory bioassay on citrus red mite, Panonychus citri (Mcg), showed that compound 1 possessed the following properties. (i) Powerful contact toxicity with an LC50 of 5.2 mg litre,1 after 24 h that was similar to that of pyridaben (LC50 = 3.4 mg litre,1) and significantly superior to that of omethoate (LC50 = 122 mg litre,1). Furthermore, its LC90 was 13.4 mg litre,1 after 24 h, which is significantly superior to both pyridaben (LC90 = 69.6 mg litre,1) and omethoate (LC90 = 453 mg litre,1). (ii) Quick-acting acaricidal activity. At identical concentrations, compound 1 was much faster-acting than pyridaben or omethoate. (iii) Compound 1 had strong corrosive action on the cuticle of P. citri but no phytotoxicity to plants. Copyright © 2006 Society of Chemical Industry [source] | ||||||||||