Choice Reaction Time Task (choice + reaction_time_task)

Distribution by Scientific Domains


Selected Abstracts


Interactions between alcohol and caffeine in relation to psychomotor speed and accuracy

HUMAN PSYCHOPHARMACOLOGY: CLINICAL AND EXPERIMENTAL, Issue 3 2002
Michelle Mackay
Abstract Unlike other CNS depressants, alcohol intoxication can be associated with increased error rates, coupled with unaffected (or speeded) response rates during psychomotor and cognitive processing. The present study examined whether concurrent consumption of caffeine may differentially affect these aspects of alcohol and performance. A randomised, double-blind, placebo-controlled design was utilised in which 64 healthy young volunteers received either 0.66,g/kg alcohol, caffeine (110,120,mg), both or neither. Performance was assessed using a four choice reaction time task (FCRT) with elements of repetitive (predictable) and random stimuli sequences and the digit symbol substitution task (DSST). Individuals on alcohol made significantly more errors during both fixed and random FCRT sequences, and there was evidence of weak antagonism of these effects by caffeine on the latter measure. On the DSST test of psychomotor speed, alcohol was associated with a significant slowing, the caffeine group were significantly faster and there was clear antagonism of the effects of alcohol by caffeine. These findings confirm that alcohol consumption is associated a greater number of errors and provide some evidence for task-specific antagonism of alcohol's cognitive effects by caffeine. Copyright © 2002 John Wiley & Sons, Ltd. [source]


Histamine H1 receptor blockade predominantly impairs sensory processes in human sensorimotor performance

BRITISH JOURNAL OF PHARMACOLOGY, Issue 1 2009
P Van Ruitenbeek
Background and purpose:, Centrally active antihistamines impair cognitive performance, particularly sensorimotor performance. The aim of the present study was to further elucidate the scarcely studied subprocesses involved in sensorimotor performance, which may be affected by H1 receptor blockade. Better knowledge about the cognitive deficits associated with histamine dysfunction can contribute to better treatment of clinical disorders in which histamine hypofunction may be a contributing factor, such as in schizophrenia. Experimental approach:, Interactions of dexchlorpheniramine with specific task manipulations in a choice reaction time task were studied. Task demands were increased at the level of sensory subprocesses by decreasing stimulus quality, and at the level of motor subprocesses by increasing response complexity. A total of 18 healthy volunteers (9 female) aged between 18 and 45 years participated in a three-way, double-blind, crossover design. Treatments were single oral doses of 4 mg dexchlorpheniramine, 1 mg lorazepam and placebo. Behavioural effects were assessed by measuring reaction times and effects on brain activity by event-related potentials. Key results:, Dexchlorpheniramine significantly slowed reaction times, but did not significantly interact with task manipulations. However, it did significantly interact with stimulus quality, as measured by event-related potentials. Lorazepam slowed reaction times and interacted with perceptual manipulations, as shown by effects on reaction times. Conclusions and implications:, The results confirm that the histamine system is involved in sensory information processing and show that H1 blockade does not affect motoric information processing. Histamine hypofunction in clinical disorders may cause impaired sensory processing, which may be a drug target. [source]


What shields some can shackle others: the approach-related consequences of threat categorisations vary by agreeableness

EUROPEAN JOURNAL OF PERSONALITY, Issue 7 2005
Michael D. Robinson
It is common to think that threat categorisation tendencies (TCTs) should undermine a person's subjective well-being. However, recent research has suggested that the hedonic impact of such tendencies varies considerably according to a person's traits. The present research seeks to extend such a perspective by considering potential interactions between TCTs and the trait of agreeableness. TCTs were measured through the use of choice reaction time tasks contrasting the threat and non-threat categories. As expected, TCTs were not correlated with the trait of agreeableness, but interacted with this trait in predicting the dependent measures. Within three studies involving 184 undergraduates, TCTs were associated with the higher levels of approach-related behaviour and positive emotion among disagreeable individuals, but lower levels of these same variables among agreeable individuals. The authors suggest that threat categorisation tendencies psychologically protect or burden the individual, depending on the levels of agreeableness. Copyright © 2005 John Wiley & Sons, Ltd. [source]


Resource allocation and fluid intelligence: Insights from pupillometry

PSYCHOPHYSIOLOGY, Issue 1 2010
Elke Van Der Meer
Abstract Thinking is biological work and involves the allocation of cognitive resources. The aim of this study was to investigate the impact of fluid intelligence on the allocation of cognitive resources while one is processing low-level and high-level cognitive tasks. Individuals with high versus average fluid intelligence performed low-level choice reaction time tasks and high-level geometric analogy tasks. We combined behavioral measures to examine speed and accuracy of processing with pupillary measures that indicate resource allocation. Individuals with high fluid intelligence processed the low-level choice reaction time tasks faster than normal controls. The task-evoked pupillary responses did not differ between groups. Furthermore, individuals with high fluid intelligence processed the high-level geometric analogies faster, more accurately, and showed greater pupil dilations than normal controls. This was only true, however, for the most difficult analogy tasks. In addition, individuals with high fluid intelligence showed greater preexperimental pupil baseline diameters than normal controls. These results indicate that individuals with high fluid intelligence have more resources available and thus can solve more demanding tasks. Moreover, high fluid intelligence appears to be accompanied by more task-free exploration. [source]