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Catalytic Asymmetric Synthesis (catalytic + asymmetric_synthesis)
Selected AbstractsChemInform Abstract: Catalytic Asymmetric Syntheses of ICI-199441 and CP-99994 Using Nitro-Mannich Reaction.CHEMINFORM, Issue 33 2002Natsuko Tsuritani Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C-3 PositionADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 9 2010Feng Zhou Abstract The 3,3,-disubstituted oxindole structural motif is a prominent feature in many alkaloid natural products, which include all kinds of tetrasubstituted carbon stereocenters, spirocyclic or not, all-carbon or heteroatom-containing. The catalytic asymmetric synthesis of the tetrasubstituted carbon stereocenter at the C-3 position of the oxindole framework integrates new synthetic methods and chiral catalysts, reflects the latest achievements in asymmetric catalysis, and facilitates the synthesis of sufficient quantities of related compounds as potential medicinal agents and biological probes. This review summarizes the recent progress in this area, and applications in the total synthesis of related bioactive compounds. [source] Catalytic Asymmetric Synthesis of Branched Chiral Allylic Phenyl Ethers from (E)-Allylic AlcoholsADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 18 2009Angela Abstract The first di-,-amidate dipalladium complexes and a new di-,-carboxylate dipalladium complex of the COP (cobalt oxazoline palladacycle) palladium(II) catalyst family are reported and characterized crystallographically. The di-,-amidate complex 3 and its enantiomer (ent - 3) are the first asymmetric catalysts that allow commercially available, or readily accessible, (E)-2-alken-1-ols to be transformed to enantioenriched branched allylic aryl ethers upon reaction of their trichloroacetimidate derivatives with phenols. The 3-aryloxy-1-alkene products are formed in high enantiomeric purity (typically 90,98% ee) and useful yields (61,88%). [source] Catalytic Asymmetric Synthesis of Complex Polypropionates: Lewis Base Catalyzed Aldol Equivalents in the Synthesis of Erythronolide,B,ANGEWANDTE CHEMIE, Issue 14 2010Binita Chandra 8 aus 10: Stereoselektive, Lewis-Base-katalysierte aldolanaloge Reaktionen lieferten acht der zehn Stereozentren, die für die Synthese von Erythronolid,B benötigt werden. Insgesamt wurden sogar alle elf Stereozentren des Erythromycin-Aglycons direkt oder indirekt über katalytische asymmetrische aldolanaloge Additionen erhalten (siehe Schema). [source] Catalytic Asymmetric Synthesis of Substituted 3-Hydroxy-2-Oxindoles,ANGEWANDTE CHEMIE, Issue 4 2010Nadine Keinen Ärger mehr mit der konkurrierenden doppelten Addition gibt es, wenn chirale Scandium(III)- und Indium(III)-Komplexe zur Katalyse der Addition von Indolen und anderen ,-Nucleophilen an N-alkylierte und ungeschützte Isatine eingesetzt werden (siehe Bild). Die biologisch wichtigen substituierten 3-Hydroxy-2-oxindole entstehen dabei in hoher Ausbeute und mit hoher Enantioselektivität. Tf=Trifluormethansulfonyl. [source] ChemInform Abstract: Catalytic Asymmetric Synthesis of R207910.CHEMINFORM, Issue 39 2010Yutaka Saga Abstract The first asymmetric synthesis of the potent anti-tuberculosis drug (VI) involves two key catalytic transformations: an enantioselective proton migration reaction of dihydroquinolinone (I) using an in situ generated yttrium catalyst, and a CuF-catalyzed highly diastereoselective allylation of the resulting quinolinone (II). [source] ChemInform Abstract: Catalytic Asymmetric Synthesis of 2,5-Naphthylpyrrolidine.CHEMINFORM, Issue 32 2010Johannes F. Teichert Abstract Based on an Ir-catalyzed double allylic amination with ammonia, the chiral title compound (VI) is prepared. [source] ChemInform Abstract: Phosphine-Catalyzed Formation of Carbon,Sulfur Bonds: Catalytic Asymmetric Synthesis of ,-Thioesters.CHEMINFORM, Issue 30 2010Jianwei Sun Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Catalytic Asymmetric Synthesis of Branched Chiral Allylic Phenyl Ethers from (E)-Allylic Alcohols.CHEMINFORM, Issue 18 2010Angela C. Olson Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Practical Catalytic Asymmetric Synthesis of Diaryl-, Aryl Heteroaryl-, and Diheteroarylmethanols.CHEMINFORM, Issue 4 2010Luca Salvi Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: A Bench-Stable Homodinuclear Ni2,Schiff Base Complex for Catalytic Asymmetric Synthesis of ,-Tetrasubstituted anti-,,,-Diamino Acid Surrogates.CHEMINFORM, Issue 26 2008Zhihua Chen Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: En Route to an Efficient Catalytic Asymmetric Synthesis of AS-3201.CHEMINFORM, Issue 3 2008Tomoyuki Mashiko Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Convenient Preparation of Chiral Phase-Transfer Catalysts with Conformationally Fixed Biphenyl Core for Catalytic Asymmetric Synthesis of ,-Alkyl- and ,,,-Dialkyl-,-amino Acids: Application to the Short Asymmetric Synthesis of BIRT-377.CHEMINFORM, Issue 41 2007Yong-Gang Wang Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Catalytic Asymmetric Synthesis of Allylic Aryl Ethers.CHEMINFORM, Issue 29 2007Stefan F. Kirsch Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Direct Catalytic Asymmetric Synthesis of anti-1,2-Amino Alcohols and syn-1,2-Diols through Organocatalytic anti-Mannich and syn-Aldol Reactions.CHEMINFORM, Issue 23 2007S. S. V. Ramasastry Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Efficient Catalytic Asymmetric Synthesis of trans-5-Aryl-2-substituted Cyclohexanones by Rhodium-Catalyzed Conjugate Arylation of Racemic 6-Substituted Cyclohexenones.CHEMINFORM, Issue 19 2007Qian Chen Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Second Generation Catalytic Asymmetric Synthesis of Tamiflu: Allylic Substitution Route.CHEMINFORM, Issue 17 2007Tsuyoshi Mita Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Catalytic Asymmetric Synthesis of (S)-Oxybutynin and a Versatile Intermediate for Antimuscarinic Agents.CHEMINFORM, Issue 9 2005Shuji Masumoto Abstract For Abstract see ChemInform Abstract in Full Text. [source] Cu-Catalyzed Enantioselective Conjugate Addition of Alkylzincs to Cyclic Nitroalkenes: Catalytic Asymmetric Synthesis of Cyclic ,-Substituted Ketones.CHEMINFORM, Issue 44 2002Courtney A. Luchaco-Cullis Abstract For Abstract see ChemInform Abstract in Full Text. [source] ChemInform Abstract: Catalytic Asymmetric Synthesis of Cyclopentenones from Propargyl Malonates and Allylic Acetate by Successive Action of Homogeneous Palladium(II) and Cobalt on Charcoal Catalysts in a One-Pot Reaction.CHEMINFORM, Issue 11 2002Seung Uk Son Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Three-Component Catalytic Asymmetric Synthesis of Aliphatic Amines.CHEMINFORM, Issue 7 2002James R. Porter Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Catalytic Asymmetric Synthesis of 1,1,-Spirobi[indan-3,3,-dione] via a Double Intramolecular C,H Insertion Process.CHEMINFORM, Issue 52 2001Teruki Takahashi Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Catalytic Asymmetric Synthesis of Highly Functionalized Cyclopentenes by a [3 + 2] Cycloaddition.CHEMINFORM, Issue 48 2001Huw M. L. Davies Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Distinct Advantage of the in situ Generation of Quaternary Ammonium Fluorides under Phase-Transfer Conditions Toward Catalytic Asymmetric Synthesis.CHEMINFORM, Issue 34 2001Takashi Ooi Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Catalytic Asymmetric Synthesis of 3-(,-Hydroxy-,-carbonyl) Oxindoles by a ScIII -Catalyzed Direct Aldol-Type ReactionCHEMISTRY - A EUROPEAN JOURNAL, Issue 12 2010Ke Shen Abstract A direct catalytic asymmetric aldol-type reaction of 3-substituted-2-oxindoles with glyoxal derivatives and ethyl trifluoropyruvate, catalyzed by a chiral N,N, -dioxide,Sc(OTf)3 (Tf=trifluoromethanesulfonyl) complex, has been developed that tolerates a wide range of substrates. The reaction proceeds in good yields and excellent enantioselectivities (up to 93,% yield, 99:1 diastereomeric ratio (dr), and >99,% enantiomeric excess (ee)) under mild conditions, to deliver 3-(,-hydroxy-,-carbonyl) oxindoles with vicinal quaternary,tertiary or quaternary,quaternary stereocenters. Even with 1,mol,% catalyst loading or on scaleup (10,mmol of starting material), maintenance of ee was observed, which showed the potential value of the catalyst system. In studies probing the reaction mechanism, a positive nonlinear effect was observed and ScIII -based enolate intermediates were detected by using ESIMS. On the basis of the experimental results and previous reports, a possible catalytic cycle was assumed. [source] | ||||||||||||||||||||||