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Carboxymethyl Chitosan (carboxymethyl + chitosan)
Selected AbstractsAntibacterial activity of cationically modified cotton fabric with carboxymethyl chitosanJOURNAL OF APPLIED POLYMER SCIENCE, Issue 3 2008Amira M. El-Shafei Abstract A water-soluble carboxymethyl chitosan was prepared with a view to develop a multifunctional finish on cotton. Carboxymethyl chitosan (CMCTS) was synthesized by chemical reaction of chitosan with monochloroacetic acid under alkaline condition. The water soluble CMCTS was applied to cationized cotton with different concentrations. The treated fabrics were characterized through monitoring the textile physical properties and for the antibacterial activity against Escherichia coli DSMZ 498 and Micrococcus luteus ATCC 9341. The results obtained show that the physical properties of the treated fabrics are improved by increasing the CMCTS concentration, as well as the antibacterial activity. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2008 [source] Synthesis, Characterization and Drug Release Behavior of pH-Responsive O-carboxymethyl Chitosan-graft-poly(N-vinylpyrrolidone) Hydrogel Beads,ADVANCED ENGINEERING MATERIALS, Issue 12 2009Liwei Ma In this work, the carboxymethyl chitosan (CMCTS) grafted poly(N-vinylpyrrolidone) (PVP) copolymers were synthesized. The hydrogel beads containing VB2 were prepared from the copolymers by an ionic crosslinked. The experimental results shown that VB2 drug release rate from those beads decreased with the increasing grafting percentage, crosslinker concentration and pH value of the medium. Besides, the beads have the better control ability for releasing of model drug than CMCTS does. [source] Bioactivity of novel carboxymethyl chitosan scaffold incorporating MTA in a tooth modelINTERNATIONAL ENDODONTIC JOURNAL, Issue 10 2010R. Budiraharjo Budiraharjo R, Neoh KG, Kang ET, Kishen A. Bioactivity of novel carboxymethyl chitosan scaffold incorporating MTA in a tooth model. International Endodontic Journal, 43, 930,939, 2010. Abstract Aim, To characterise the bioactivity of a novel carboxymethyl chitosan (CMCS) scaffold with and without incorporating mineral trioxide aggregate (MTA) in a tooth model. Methodology, Cross-linked CMCS scaffold (CaC) and MTA-coated CaC (CaMT) scaffold were prepared by freeze-drying. The bioactivity of the scaffolds was tested in vitro in four different mineralisation solutions (bulk system) and ex vivo in simulated body fluid (SBF) in the tooth model. After mineralisation, the mineral deposits on the scaffolds were analysed using scanning electron microscopy, energy dispersive X-ray, and inductively coupled plasma mass spectroscopy. All data were statistically analysed using the two-sample t -test (P < 0.05). Results, Hydroxyapatite (HAP) deposition was observed on CaC and CaMT scaffolds after 1 week of mineralisation in the tooth model and in the bulk system. The deposition was significantly higher (P < 0.05) on CaMT scaffold than that on CaC scaffold. The amount of HAP formed in the tooth model was significantly lower (P < 0.05) than that in the bulk solution. Conclusions, The CMCS scaffolds are bioactive and capable of biomineralisation by forming HAP within a tooth model ex vivo. The bioactivity of the CMCS scaffold can be enhanced by incorporating MTA. [source] Preparation of quaternized carboxymethyl chitosan and its capacity to flocculate COD from printing wastewaterJOURNAL OF APPLIED POLYMER SCIENCE, Issue 1 2010Zhao-Sheng Cai Abstract A bioflocculant, quaternized carboxymethyl chitosan (QCMC), was developed by the quaternization of N,O-carboxymethyl chitosan (N,O-CMC) and characterized by FTIR, 1H-NMR, GPC, and potentiometry. The efficiency of the removal of chemical oxygen demand (COD) in printing wastewater by this flocculant was further reported. Results indicated that the capacity of QCMC to remove the COD from tested wastewater was the best one among the investigated flocculants. The pH had great influence on this capacity and the suitable pH for QCMC to treat the tested wastewater was about 5.0. The utilization of aid-flocculant, especially bentonite, could improve this capacity obviously, and the increase of mass ratio of bentonite to QCMC resulted in the increase of the capacities of complex flocculant to remove the COD from the tested wastewater. When the mass ratio of bentonite to QCMC was 40, pH of wastewater was 5.0 and amount of complex flocculant in the wastewater was from 2500 to 3142 mg L,1, the removal ratio of COD was more than 80%. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010 [source] Antibacterial activity of cationically modified cotton fabric with carboxymethyl chitosanJOURNAL OF APPLIED POLYMER SCIENCE, Issue 3 2008Amira M. El-Shafei Abstract A water-soluble carboxymethyl chitosan was prepared with a view to develop a multifunctional finish on cotton. Carboxymethyl chitosan (CMCTS) was synthesized by chemical reaction of chitosan with monochloroacetic acid under alkaline condition. The water soluble CMCTS was applied to cationized cotton with different concentrations. The treated fabrics were characterized through monitoring the textile physical properties and for the antibacterial activity against Escherichia coli DSMZ 498 and Micrococcus luteus ATCC 9341. The results obtained show that the physical properties of the treated fabrics are improved by increasing the CMCTS concentration, as well as the antibacterial activity. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2008 [source] Calcium-carboxymethyl chitosan hydrogel beads for protein drug delivery systemJOURNAL OF APPLIED POLYMER SCIENCE, Issue 5 2007Zonghua Liu Abstract In this study, carboxymethyl chitosan (CMC) hydrogel beads were prepared by crosslinking with Ca2+. The pH-sensitive characteristics of the beads were investigated by simulating gastrointestinal pH conditions. As a potential protein drug delivery system, the beads were loaded with a model protein (bovine serum albumin, BSA). To improve the entrapment efficiency of BSA, the beads were further coated with a chitosan/CMC polyelectrolyte complex (PEC) membrane by extruding a CMC/BSA solution into a CaCl2/chitosan gelation medium. Finally, the release studies of BSA-loaded beads were conducted. We found that, the maximum swelling ratios of the beads at pH 7.4 (17,21) were much higher than those at pH 1.2 (2,2.5). Higher entrapment efficiency (73.2%) was achieved in the chitosan-coated calcium-CMC beads, compared with that (44.4%) in the bare calcium-CMC beads. The PEC membrane limited the BSA release, while the final disintegration of beads at pH 7.4 still leaded to a full BSA release. Therefore, the chitosan-coated calcium-CMC hydrogel beads with higher entrapment efficiency and proper protein release properties were a promising protein drug carrier for the site-specific release in the intestine. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 103: 3164,3168, 2007 [source] | ||||||||||