Campestris L. (campestri + l)

Distribution by Scientific Domains
Chemistry75%

Kinds of Campestris L.

  • brassica campestri l.
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    Selected Abstracts

    Chinese Cabbage (Brassica campestris L.) does not Improve Glucose Tolerance, Serum Insulin, or Blood Lipid Profiles in a Rat Model of Type-2 Diabetes

    JOURNAL OF FOOD SCIENCE, Issue 9 2008
    M.S. Islam
    ABSTRACT:, The present study was conducted to investigate the effects of a low (0.5%) and a high (2.0%) dietary dose of freeze-dried Chinese cabbage (CC) (Brassica campestris L.) powder in a type-2 diabetes (T2D) model of rats. Five-week-old male Sprague,Dawley rats were fed a high fat (HF)-containing diet for 2 wk then randomly divided into 4 groups of 8 animals, namely: normal control (NC), diabetic control (DBC), Chinese cabbage low (CCL, 0.5%), and Chinese cabbage high (CCH, 2.0%) groups. Diabetes was induced by an intraperitoneal injection of streptozotocin (STZ; 40 mg/kg body weight) in all groups except the NC group. After 4 wk feeding of experimental diets, although food intake was not different among the DBC, CCL, and CCH groups, body weight gain was significantly (P < 0.05) higher in the CCH group compared to the DBC group. Relatively higher serum insulin concentrations and better glucose tolerance were observed in the CC-fed groups compared to the DBC group; however, the results were not significantly different. Fasting blood glucose, blood glycated hemoglobin (HbA1c), liver weight, and liver glycogen levels were not influenced by the CC-containing diets. Additionally, hypertriglyceridemic tendencies were observed in the CC-fed groups compared to the NC and DBC groups, while difference observed for total-, HDL-, and LDL-cholesterols between the groups were negligible. Results of this study suggest that up to 2% dietary dose of freeze-dried CC is not significantly effective to reduce diabetes-related symptoms in an HF diet-fed STZ-induced T2D model of rats. [source]

    A new method for the synthesis and herbicidal activity of 3-phenoxy-6-(1H- (substituted)pyrazol-1-yl) pyridazines

    JOURNAL OF HETEROCYCLIC CHEMISTRY, Issue 4 2009
    Fang-Zhong Hu
    A series of 3-substituted phenoxy-6-((substituted)1H -pyrazol-1-yl) pyridazines were synthesized from the condensation of various phenols and 3-chloro-6-(1H -pyrazol-1-yl) pyridazine 2 or 3-chloro-6-(5,-methyl-4-ethoxycarbonyl- 1H -pyrazol-1-yl) pyridazine 6 in N,N-dimethylformamide (DMF) at 120°C with K2CO3 as an acid receptor. The intermediates 2 or 6 were obtained from the cyclization of 3-chloro-6-hydrazinyl pyridazine 1 with 3-dimethylamino-acrylaldehyde or ethyl 2-((dimethylamino) methylene)-3-oxobutanoate in n -butanol under reflux, respectively, and side products 3 or 7 were also generated. All of the title compounds were confirmed by 1H NMR, infrared spectometry (IR) and elemental analyses. Preliminary bioassay indicated that some of the title compounds showed high inhibitory activity against Brassica campestris L. (B. campestris) and moderate inhibitory activity against Echinochloa crusgalli. For example, the inhibition percentages of compound 4b and 4c against B. campestris were both 94% at 10 ,g/mL. J. Heterocyclic Chem., (2009). [source]

    A steroid fraction of chloroform extract from bee pollen of Brassica campestris induces apoptosis in human prostate cancer PC-3 cells

    PHYTOTHERAPY RESEARCH, Issue 11 2007
    Yao-Dong Wu
    Abstract Bee pollen of Brassica campestris L. is widely used in China as a natural food supplement and an herbal medicine in strengthening the body's resistance against diseases including cancer. The present study was carried out to investigate the effect of a steroid fraction of chloroform extract from bee pollen of Brassica campestris L. on human cancer cell viability. Our studies show that among nine cancer cell lines of different origin (PC-3, LNCaP, MCF-7, Hela, BEL-7402, BCG-823, KB, A549 and HO8910), this steroid fraction displayed the strongest cytotoxicity in human prostate cancer PC-3 cells. The mode of cell death appeared to be apoptosis in PC-3 cells, as shown by flow-cytometric analysis and fluorescence microscopes. Caspase-3 activity was obviously enhanced after the cells were treated with the fraction. A time-dependent decrease in the expression of anti-apoptotic protein Bcl-2 was also observed by Western blot analysis. It is suggested that the steroid fraction could induce cytotoxicity in prostate cancer PC-3 cells by triggering apoptosis. The studies indicate that the steroid fraction of chloroform extract from bee pollen of Brassica campestris L. may be a promising candidate for the treatment of advanced prostate cancer. Copyright © 2007 John Wiley & Sons, Ltd. [source]