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Caffeoylquinic Acid (caffeoylquinic + acid)
Selected AbstractsIdentification of isomeric dicaffeoylquinic acids from Eleutherococcus senticosus using HPLC-ESI/TOF/MS and 1H-NMR methodsPHYTOCHEMICAL ANALYSIS, Issue 6 2002Ari Tolonen Abstract Liquid chromatography,electrospray time-of-flight mass spectrometry (HPLC-ESI/TOF/MS) and a novel NMR technique, developed to maximise the sensitivity obtained from the standard NMR spectrometer, have been applied to the identification of the phenolic constituents of Eleutherococcus senticosus. In addition, molecular modelling and dihedral bond angle calculations based on the vicinal 3JHH -coupling constants have been used in the unambiguous assignment of signals in the 1H-NMR spectra. 5,- O -Caffeoylquinic acid and three isomeric compounds, 1,,5,- O -dicaffeoylquinic acid, 3,,5,- O -dicaffeoylquinic acid and 4,,5,- O -dicaffeoylquinic acid, have been isolated and identified from a sample. The isolation and structure determination of the latter two compounds are reported for the first time from this plant. Copyright © 2002 John Wiley & Sons, Ltd. [source] Moringa oleifera: a food plant with multiple medicinal usesPHYTOTHERAPY RESEARCH, Issue 1 2007Farooq Anwar Abstract Moringa oleifera Lam (Moringaceae) is a highly valued plant, distributed in many countries of the tropics and subtropics. It has an impressive range of medicinal uses with high nutritional value. Different parts of this plant contain a profile of important minerals, and are a good source of protein, vitamins, , -carotene, amino acids and various phenolics. The Moringa plant provides a rich and rare combination of zeatin, quercetin, , -sitosterol, caffeoylquinic acid and kaempferol. In addition to its compelling water purifying powers and high nutritional value, M. oleifera is very important for its medicinal value. Various parts of this plant such as the leaves, roots, seed, bark, fruit, flowers and immature pods act as cardiac and circulatory stimulants, possess antitumor, antipyretic, antiepileptic, antiinflammatory, antiulcer, antispasmodic, diuretic, antihypertensive, cholesterol lowering, antioxidant, antidiabetic, hepatoprotective, antibacterial and antifungal activities, and are being employed for the treatment of different ailments in the indigenous system of medicine, particularly in South Asia. This review focuses on the detailed phytochemical composition, medicinal uses, along with pharmacological properties of different parts of this multipurpose tree. Copyright © 2006 John Wiley & Sons, Ltd. [source] Hierarchical scheme for liquid chromatography/multi-stage spectrometric identification of 3,4,5-triacyl chlorogenic acids in green Robusta coffee beansRAPID COMMUNICATIONS IN MASS SPECTROMETRY, Issue 15 2010Rakesh Jaiswal Liquid chromatography/multi-stage spectrometry (LC/MSn) (n,=,2,4) has been used to detect and characterize in green Robusta coffee beans eight quantitatively minor triacyl chlorogenic acids with seven of them not previously reported in nature. These comprise 3,4,5-tricaffeoylquinic acid (Mr 678); 3,5-dicaffeoyl-4-feruloylquinic acid, 3-feruloyl-4,5-dicaffeoylquinic acid and 3,4-dicaffeoyl-5-feruloylquinic acid (Mr 692); 3-caffeoyl-4,5-diferuloylquinic acid and 3,4-diferuloyl-5 - caffeoylquinic acid (Mr 706); and 3,4-dicaffeoyl-5-sinapoylquinic acid and 3-sinapoyl-4,5-dicaffeoylquinic acid (Mr 722). Structures have been assigned on the basis of LC/MSn patterns of fragmentation. A new hierarchical key for the identification of triacyl quinic acids is presented, based on previously established rules of fragmentation. Fifty-two chlorogenic acids have now been characterized in green Robusta coffee beans. In this study five samples of green Robusta coffee beans and fifteen samples of Arabica coffee beans were analyzed with triacyl chlorogenic acids only found in Robusta coffee bean extracts. These triacyl chlorogenic acids could be considered as useful phytochemical markers for the identification of Robusta coffee beans. Copyright © 2010 John Wiley & Sons, Ltd. [source] Detection of phenolic oxidation products in cider apple juice by high-performance liquid chromatography electrospray ionisation ion trap mass spectrometryRAPID COMMUNICATIONS IN MASS SPECTROMETRY, Issue 9 2004S. Bernillon Juice was prepared from cider apples of the cultivar "Kermerrien" under oxidative conditions. After isolation by solid-phase extraction, the phenolic fraction was subjected to high-performance liquid chromatography/electrospray ionisation mass spectrometry. SIM scans were performed at m/z values obtained in model solutions. The oxidation products, resulting from coupling between a molecule of caffeoylquinic acid and caffeoylquinic acid, catechin or dimeric flavan-3-ol, were detected. Copyright © 2004 John Wiley & Sons, Ltd. [source] Changes in Radical-scavenging Activity and Components of Mulberry Fruit During MaturationJOURNAL OF FOOD SCIENCE, Issue 1 2006Tomoyuki Oki ABSTRACT Extracts of mulberry fruits (Morus sp.) were prepared from 8 cultivars harvested at 4 stages of maturity, and their radicalscavenging activity, anthocyanin content, and total phenolic content were measured. The radical-scavenging activity was evaluated by a spectrophotometric assay using the 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) in a 96-well microplate. Mulberry fruit extracts exhibited the DPPH-scavenging activities, ranging from 2.5 to 20.3 ,mol-Trolox equiv/g-FW. Their activities were variable during maturation, and the highest activity was observed in the fully mature mulberry fruit in all cultivars. Anthocyanin was scarcely present in the immature mulberry fruits; however, its content increased as the fruit matured in all cultivars. On the other hand, all immature mulberry fruits contained non-anthocyanin phenolic compound. An on-line high-performance liquid chromatography (HPLC) method for the detection of DPPH-scavenging compounds revealed the difference in predominant radical scavengers between the immature and fully mature stages in the Miran 5 cultivar. Four major radical scavengers in the Miran 5 cultivar were assigned to 2 caffeoylquinic acids (chlorogenic acid and its isomer) and 2 anthocyanins (cyanidin 3-glucoside and cyanidin 3-rutinoside) in the immature and fully mature stages, respectively, by LC-ESI-MS/MS analysis. The change in the content of 4 compounds in mulberry fruits during maturation demonstrated that the most likely contributors to the DPPH-scavenging activity were caffeoylquinic acids in the immature mulberry and anthocyanins in the mature and fully mature mulberry. [source] | ||||||||||